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22  structures 5258  species 2  interactions 54224  sequences 211  architectures

Clan: ABC_membrane (CL0241)

Summary

ABC transporter membrane domain clan Add an annotation

This clan includes families that are the membrane components of ABC transporter complexes. In general these regions are composed of six transmembrane helices [1].

This clan contains 4 families and the total number of domains in the clan is 54224. The clan was built by A Bateman.

Literature references

  1. Chang G; , J Mol Biol. 2003;330:419-430.: Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation. PUBMED:12823979 EPMC:12823979

Members

This clan contains the following 4 member families:

ABC_membrane ABC_membrane_2 ABC_membrane_3 SbmA_BacA

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
ABC_membrane (PF00664) 51056 (94.2%) View
ABC_membrane_2 (PF06472) 2221 (4.1%) View
SbmA_BacA (PF05992) 817 (1.5%) View
ABC_membrane_3 (PF13748) 130 (0.2%) View
Total: 4 Total: 54224 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 2 interactions for this clan. More...

Interacting families
A B
ABC_membrane ABC_tran
ABC_membrane

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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