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191  structures 2992  species 4  interactions 11034  sequences 281  architectures

Clan: B_Fructosidase (CL0143)

Summary

Beta fructosidase superfamily Add an annotation

This beta fructosidase superfamily [4] is composed of glycosyl hydrolase families. The members of this clan adopt a five-bladed beta-propeller fold [2-3]. The beta-fructosidase superfamily is also known as furanosidase superfamily [4].

This clan contains 5 families and the total number of domains in the clan is 11034. The clan was built by J Mistry.

Literature references

  1. Hettwer U, Jaeckel FR, Boch J, Meyer M, Rudolph K, Ullrich MS; , Appl Environ Microbiol 1998;64:3180-3187.: Cloning, nucleotide sequence, and expression in Escherichia coli of levansucrase genes from the plant pathogens Pseudomonas syringae pv. glycinea and P. syringae pv. phaseolicola. PUBMED:9726857 EPMC:9726857
  2. Nurizzo D, Turkenburg JP, Charnock SJ, Roberts SM, Dodson EJ, McKie VA, Taylor EJ, Gilbert HJ, Davies GJ; , Nat Struct Biol 2002;9:665-668.: Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold. PUBMED:12198486 EPMC:12198486
  3. Alberto F, Bignon C, Sulzenbacher G, Henrissat B, Czjzek M; , J Biol Chem 2004;279:18903-18910.: The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases. PUBMED:14973124 EPMC:14973124
  4. Naumoff DG; , Proteins. 2001;42:66-76.: beta-fructosidase superfamily: homology with some alpha-L-arabinases and beta-D-xylosidases. PUBMED:11093261 EPMC:11093261

Members

This clan contains the following 5 member families:

DUF377 Glyco_hydro_32N Glyco_hydro_43 Glyco_hydro_62 Glyco_hydro_68

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Glyco_hydro_43 (PF04616) 5170 (46.9%) View
Glyco_hydro_32N (PF00251) 4354 (39.5%) View
DUF377 (PF04041) 965 (8.7%) View
Glyco_hydro_68 (PF02435) 358 (3.2%) View
Glyco_hydro_62 (PF03664) 187 (1.7%) View
Total: 5 Total: 11034 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 4 interactions for this clan. More...

Interacting families
A B
Glyco_hydro_68 Glyco_hydro_68
Glyco_hydro_43 Glyco_hydro_43
Glyco_hydro_32N Glyco_hydro_32N
Glyco_hydro_32C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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