Sequence alignment for CL0005

PF00050

ISK6_BOVIN/30-80CAEFKDP.......KVYCT...RESNP--HC------GSDGQ---TYGN--KCAF....CKAVM.KS-----------GG
AGRIN_CHICK/199-244CKKT............ACP...VVVAP--VC------GSDYS---TYSN--ECELEKAQC.....NQ-----------QR
AGRIN_CHICK/274-319CPAS.............CS..GVAESI--VC------GSDGK---DYRS--ECDLNKHAC.....DK-----------QE
AGRIN_CHICK/417-462CDRIT............CD...GTYRP--VC------ARDSR---TYSN--DCERQKAEC.....HQ-----------KA
AGRIN_CHICK/492-536CQQV.............CQ...GRYDP--VC------GSDNR---TYGN--PCELNAMAC.....VL-----------KR
AGRIN_CHICK/557-601CPTE.............CV...PSSQP--VC------GTDGN---TYGS--ECELHVRAC.....TQ-----------QK
AGRIN_CHICK/622-666CPR..............CE..QQPLAQ--VC------GTDGL---TYDN--RCELRAASC.....QQ-----------QK
AGRIN_CHICK/706-751CDFT.............CL..AVPRSP--VC------GSDDV---TYAN--ECELKKTRC.....EK-----------RQ
AGRIN_CHICK/923-969CPSP............LCS..EANMTK--VC------GSDGV---TYGD--QCQLKTIAC.....RQ-----------GQ
ISK1_BOVIN/32-79CTNEVNG..........CP...RIYNP--VC------GTDGV---TYSN--ECLL....CMENK.ER-----------QT
AGRIN_RAT/167-212CPTT.............CF..GAPDGT--VC------GSDGV---DYPS--ECQLLSHAC.....AS-----------QE
AGRIN_RAT/237-284MLLRPEN..........CP...AQHTP--IC------GDDGV---TYEN--DCVMSRIGA.....TR-----------GL
AGRIN_RAT/311-356CDRVT............CD...GSYRP--VC------AQDGH---TYNN--DCWRQQAEC.....RQ-----------QR
AGRIN_RAT/385-429CQRV.............CS...GIYDP--VC------GSDGV---TYGS--VCELESMAC.....TL-----------GR
AGRIN_RAT/450-494CPSE.............CV...ESAQP--VC------GSDGH---TYAS--ECELHVHAC.....TH-----------QI
AGRIN_RAT/515-559CPR..............CE..HPPPGP--VC------GSDGV---TYLS--ACELREAAC.....QQ-----------QV
AGRIN_RAT/600-645CDFS.............CQ..SVPRSP--VC------GSDGV---TYGT--ECDLKKARC.....ES-----------QQ
AGRIN_RAT/818-864CPTLT............CP..EANSTK--VC------GSDGV---TYGN--ECQLKAIAC.....RQ-----------RL
FST_HUMAN/118-164CAPD.............CSN.ITWKGP--VC------GLDGK---TYRN--ECALLKARC.....KE-----------QP
FST_HUMAN/192-239CNRI.............CPEPASSEQY--LC------GNDGV---TYSS--ACHLRKATC.....LL-----------GR
FST_HUMAN/270-316CDEL.............CPD.SKSDEP--VC------ASDNA---TYAS--ECAMKEAAC.....SS-----------GV
IAC1_BOVIN/14-61CKVYTEA..........CT...REYNP--IC------DSAAK---TYSN--ECTF....CNEKM.NN-----------DA
ISK2_HUMAN/36-84CSQYRLPG.........CP...RHFNP--VC------GSDMS---TYAN--ECTL....CMKIR.EG-----------GH
IACA_PIG/7-57CNVYRSH.......LFFCT...RQMDP--IC------GTNGK---SYAN--PCIF....CSEKG.LR-----------NQ
IOV7_CHICK/28-85CSLYASGIGKDGTSWVACP...RNLKP--VC------GTDGS---TYSN--ECGI....CLYNR.EH-----------GA
IOV7_CHICK/94-150CSPYLQV.VRDGNTMVACP...RILKP--VC------GSDSF---TYDN--ECGI....CAYNA.EH-----------HT
IOV7_CHICK/159-216CSKYPSTVSKDGRTLVACP...RILSP--VC------GTDGF---TYDN--ECGI....CAHNA.EQ-----------RT
IOV7_CHICK/225-282CDQYPTRKTTGGKLLVRCP...RILLP--VC------GTDGF---TYDN--ECGI....CAHNA.QH-----------GT
IOV7_CHICK/356-413CSKYKTSTLKDGRQVVACT...MIYDP--VC------ATNGV---TYAS--ECTL....CAHNL.EQ-----------RT
IOV7_CHICK/422-472CREFQKV.......SPICT...MEYVP--HC------GSDGV---TYSN--RCFF....CNAYV.QS-----------NR
IOVO_PIPPP/8-56CSDHPKP.........ACL...QEQKP--LC------GSDNK---TYDN--KCSF....CNAVV.DS-----------NG
IOVO_CASCA/6-54CSEYPKP.........VCS...PEYMP--LC------GSDSK---TYNN--KCDF....CSAVV.ES-----------NG
IOVO_CHICK/29-86CSRFPNATDKEGKDVLVCN...KDLRP--IC------GTDGV---TYTN--DCLL....CAYSI.EF-----------GT
IOVO_CHICK/94-151CSSYANTTSEDGKVMVLCN...RAFNP--VC------GTDGV---TYDN--ECLL....CAHKV.EQ-----------GA
IOVO_COTJA/5-62CSRFPNTTNEEGKDEVVCP...DELRL--IC------GTDGV---TYNH--ECML....CFYNK.EY-----------GT
IOVO_COTJA/70-127CSRYPNTTSEDGKVTILCT...KDFSF--VC------GTDGV---TYDN--ECML....CAHNV.VQ-----------GT
IOVO_EUDEL/5-51CSGYPKP.........ACT...LEFFP--LC------GSDNQ---TYSN--KCAF....C..NA.AV-----------EK
IOVO_FRACO/5-53CSEYPKPG.........CT...MEYRP--VC------GSDNI---TYGN--KCNF....CNAVV.KS-----------NG
ISK1_RAT/32-79CPKQIMG..........CP...RIYDP--VC------GTNGI---TYPS--ECSL....CFENR.KF-----------GT
ISK3_RAT/32-79CPNTLVG..........CP...RDYDP--VC------GTDGK---TYAN--ECIL....CFENR.KF-----------GT
IPSG_CANFA/12-64CSNYKGKGS.....QIACP...RLHQP--IC------GTDHK---TYSN--ECMF....CALTL.NK-----------KF
IPSG_CANFA/68-115CTEYSDM..........CT...MDYRP--LC------GSDGK---NYSN--KCSF....CNAVK.KS-----------RG
IPSG_FELCA/8-60CSQYNRKGS.....GITCS...KEWKP--IC------GIDHK---TYSN--ECMF....CQLNQ.NK-----------RF
IPSG_FELCA/64-111CTNYSA..........ICT...MEYFP--LC------GSDGQ---EYSN--KCLF....CNEVV.KR-----------RG
IPSG_MELME/16-68CSKYNAKGS.....QFACS...RHLDP--VC------GTDHR---TYSN--ECMF....CMLTQ.NK-----------RF
ISK1_ANGAN/12-61CGEMSAMHA........CP...MNFAP--VC------GTDGN---TYPN--ECSL....CFQRQ.NT-----------KT
ISK1_CANFA/10-57CNLKVNG..........CN...KIYNP--IC------GSDGI---TYAN--ECLL....CLENK.KR-----------QT
ISK4_PIG/37-86CEHMTESPD........CS...RIYDP--VC------GTDGV---TYES--ECKL....CLARI.EN-----------KQ
SPRL1_COTJA/468-521CQDPAA...........CPS.TKDYKR--VC------GTDNK---TYDG--TCQLFGTKCQLEGTKM-----------GR
SPRL1_RAT/426-479CQDPET...........CPP.AKILDQ--AC------GTDNQ---TYAS--SCHLFATKCMLEGTKK-----------GH
SPRC_BOVIN/95-149CQDPTS...........CPAPIGEFEK--VC------SNDNK---TFDS--SCHFFATKCTLEGTKK-----------GH

PF07648

SPRL1_MOUSE/448-495CPPA------------------KILDQ..AC......GTDNQ...TYAS..SCHLFATKC-----RLEG......TKKGH
FSTL1_MOUSE/56-96CKPH------------------KR..P..VC......GSNGK...TYLN..HCELHRDAC-----LT...........GS
Q95011_CAEEL/330-376CPKD------------------EKKIP..IC......DNRNM...THPT..LCSFIQYNC-----EARN.......NEDE
Q95011_CAEEL/138-183CTNT------------------EFD.P..VC......DTNGS...VYRN..LCVFQMRRC-----ELQ........LESQ
SO3A1_HUMAN/477-511CQTD------------------SFT.P..VC......GADGI...TYLS..ACFAGC...-----...............
SO5A1_HUMAN/561-603CKIH------------------EYE.P..VC......GSDGI...TYFN..PCLAGCVNS-----GN..........LST
ISK5_HUMAN/721-761CTRE------------------SD..P..VR......DADGK...SYNN..QCTMCKAKL-----ER...........EA
ISK5_HUMAN/111-151CPDY------------------YE..A..VC......GTDGK...TYDN..RCALCAENA-----KT...........GS
ISK5_HUMAN/451-491CTRE------------------ND..P..IQ......GPDGK...MHGN..TCSMCEAFF-----QQ...........EE
ISK5_HUMAN/510-551CTRE------------------HN..P..VR......GPDGK...MHGN..KCAMCASVF-----KL..........EEE
ISK5_HUMAN/581-621CTRE------------------ND..P..IE......GLDGK...IHGN..TCSMCEAFF-----QQ...........EA
ISK5_HUMAN/239-283CTRE------------------SD..P..VR......GPDGR...MHGN..KCALCAEIF-----KQRF.......SEEN
ISK5_HUMAN/863-905CTRE------------------NN..P..VR......GPYGK...MHIN..KCAMCQSIF-----DRE.........ANE
ISK5_HUMAN/930-971CPRE------------------ND..P..VH......GADGK...FYTN..KCYMCRAVF-----LT..........EAL
ISK5_HUMAN/175-214CTRE------------------ND..P..VL......GPDGK...THGN..KCAMCAELF-----L............KE
ISK5_HUMAN/788-833CTRE------------------SD..P..VR......GPDGK...THGN..KCTMCKEKL-----EREA......AEKKK
FSTA_DANRE/277-319CPES------------------RSEEA..VC......ASDNT...TYPS..ECAMKQAAC-----SL...........GV
ISK5_HUMAN/646-691CTRE------------------ND..P..VR......GPDGK...THGN..KCAMCKAVF-----QKEN......EERKR
HTRA3_MOUSE/87-132CRCR------------------WTH.T..VC......GTDGH...TYAD..VCALQAASR-----RALQ.......VSGT
Q9W269_DROME/546-588CDYV------------------RYS.P..VC......GENNM...TYIS..ACHAGCKKL-----LV..........NSE
SO1A2_HUMAN/445-486CPSK------------------IWD.P..VC......GNNGL...SYLS..ACLAGCETS-----IG...........TG
SPRC_CAEEL/80-135CPEL------------------DGDPMDKVC......ANNNQ...TFTS..LCDLYRERC-----LCKRKSKECSKAFNA
ISK1_STRCA/23-63CAKI------------------FD..P..VC......GTDNI...LYSN..ECLLCFQNL-----QR...........KT
CO6_HUMAN/793-837CSHH------------------SED....LCV....FDTDSN...DYFTSPACKFLAEKC-----LN...........NQ
IPSG_MARMT/28-68CTRH------------------ER..P..VC......GTDHR...TYSN..ECMFCMLTQ-----NK...........GF
SO4A1_HUMAN/510-553CQPE------------------HYS.P..VC......GSDGL...MYFS..LCHAGCPAA-----TE...........TN
SO1A1_RAT/445-486CSTN------------------TWD.P..VC......GDNGV...AYMS..ACLAGCKKF-----VG...........TG
HTRA1_XENLA/91-134CPSN------------------Q...P..VC......GSDGK...TYSS..LCRLQAESK-----AVQG.......RGVA
Q95LZ2_MACFA/275-315CTRE------------------ND..P..IR......GPDGK...MHGN..LCSMCQVYF-----QA...........EN
TICN2_MOUSE/139-180CHMA------------------QLA.S..VC......GSDGH...TYSS..VCKLEQQAC-----LS...........SK
Q9D5W6_MOUSE/486-527CTTS------------------EYN.P..VC......GRDET...QYFS..PCFAGCKAT-----KK...........LR
TICN3_HUMAN/142-183CPVV------------------YPS.P..VC......GSDGH...TYSF..QCKLEYQAC-----VL...........GK
Q9VUD9_DROME/298-342CPKA------------------SLS....IC......ASNGKCVVNFPG..QCELSQWNC-----FN..........TKN
Q8K4K9_RAT/491-532CTTS------------------LYS.S..VC......GRDEK...EYFS..PCFAGCSAT-----KV...........QQ
FSTL3_MOUSE/123-165CEGL------------------PAGFQ..VC......GSDGA...TYRD..ECELRTARC-----RG...........HP
SO2A1_MOUSE/449-493CPDS------------------VFH.P..VC......GDNGV...EYLS..PCHAGCSSL-----NVS........SAAS
HTRA3_HUMAN/81-126CRCR------------------WSH.A..VC......GTDGH...TYAN..VCALQAASR-----RALQ.......LSGT
CFAI_RAT/70-109CPKA------------------GT..P..VC......ATNGR...GYPT..YCHLKSFEC-----L............HP
Q8UVG4_LEUER/460-501CSGS------------------QWE.P..VC......ADSGV...TYVS..PCLAGCKTS-----SG...........VG
Q9VUD8_DROME/260-310CTKF------------------EYS.P..IC......AHNGICIHEFAN..QCVMNTFNC-----KHRDL.....SFRAV
IPSG_PANLE/20-60CSKQ------------------LK..P..IC......GIDHK...TYSN..ECMFCLLNQ-----NK...........QF
LDTI_HIRME/6-40CPKI------------------LK..P..VC......GSDGR...TYAN..SCIARCNG.-----...............
AGRIN_DISOM/214-255CPKN------------------KQF.K..VC......GSDGV...TYAN..ECQLKTIAC-----RQ...........GS
SO1B3_HUMAN/465-506CDES------------------QWE.P..VC......GNNGI...TYLS..PCLAGCKSS-----SG...........IK
MCPI_MELCP/101-141CTLE------------------YN..P..QC......GTDGR...TYGN..PCQLKVAEC-----ES...........DG
THBI_RHOPR/60-101CDGD------------------EYK.P..VC......GSDDI...TYDN..NCRLECASI-----SS...........SP
TICN1_HUMAN/139-180CPVA------------------QSA.M..VC......GSDGH...SYTS..KCKLEFHAC-----ST...........GK
WFKN1_HUMAN/120-157CEKE------------------....PSFTC......ASDGL...TYYN..RCYMDAEAC-----LR...........GL
Q6NW92_DANRE/91-134CKSG------------------V...P..VC......GTDGR...NYNS..GCALRAASA-----RALQ.......EKQP
RECK_HUMAN/716-750CDQV------------------QD..P..VC......DTDHM...EHNN..LCTLY....-----.............QR
MCPI_MELCP/53-93CTKE------------------YN..P..QC......GTDGV...TYAN..PCTLEYAKC-----KS...........DG
RECK_HUMAN/635-671CADQ------------------FV..P..VC......GQNGR...TYPS..ACIARCV..-----.............GL
IACS_PIG/48-88CTRE------------------MD..P..IC......GTNGK...SYAN..PCIFCSEKL-----GR...........NE
IOVO_MELGA/86-126CNKA------------------LN..P..VC......GTDGV...TYDN..ECVLCAHNL-----EQ...........GT
FST_PIG/122-164CSNI------------------TWKGP..VC......GLDGK...TYRN..ECALLKARC-----KE...........QP
HTRA4_HUMAN/108-152CPTL------------------GGA....VC......GSDRR...TYPS..MCALRAENR-----AARR.......LGKV
IPSG_PANLE/71-111CTME------------------YF..P..LC......GSDGK...VYSN..KCSFCNEVV-----KR...........RG
IBD3_HIRME/6-40CTKE------------------LHR....VC......GSDGV...TYDN..ECLATCHG.-----...............
SO1B2_MOUSE/460-503CDKN------------------QWE.P..VC......GENGV...TYIS..PCLAGCKSF-----RG...........DK
IOV7_CHICK/307-347CPFI------------------LQE....VC......GTDGV...TYSN..DCSLCAHNI-----EL...........GT
Q95LZ2_MACFA/345-385CTRE------------------ND..P..IQ......GPDGK...VHGN..TCSMCEVFF-----QA...........EE
Q8QGV0_CYPCA/183-222CPRQ------------------QN.....TC......ALDGS...VYYS..MCQANAISC-----RT...........KT
Q9W271_DROME/470-512CDYV------------------HYA.P..VC......SADNI...TFIS..ACHAGCSER-----TK..........DAL
IPSG_VULVU/24-64CPRH------------------LQ..P..IC......GTDHN...TYSN..ECMFCALTL-----NK...........EF
Q8SY02_DROME/486-527CSRT------------------NYD.P..IC......GVDGV...MYYS..PCYAGCVQE-----EH...........AN
AGRIN_RAT/97-137CPAT------------------VA..P..VC......GSDAS...TYSN..ECELQRAQC-----NQ...........QR
IPSG_MELME/79-119CTMD------------------YL..P..LC......GSDGN...NYSN..KCLFCNAVL-----RS...........RG
Q8T926_TETTH/32-76CPEI------------------YS..P..VCAIQQQTGNFSQVKKDYSN..KCEACS...-----.............QS
SO1C1_HUMAN/482-523CSET------------------KWE.P..MC......GENGI...TYVS..ACLAGCQTS-----NR...........SG
FST_PIG/196-239CPEP------------------TSS.EQYLC......GNDGV...TYSS..ACHLRKATC-----LL...........GR
FST_PIG/274-316CPES------------------KSEEP..VC......ASDNA...TYAS..ECAMKEAAC-----SS...........GV
SPRC_RABIT/103-151CPAP------------------VGE.FEKVC......SNDNK...TFDS..SCHFFATKC-----TLEG......TKKGH
Q9VP16_DROME/519-563CANV------------------YDENDEIIC......GSDGY...MYTG..ETQLQCYSS-----CL...........NI

PF00050

ISK6_BOVIN/30-80K--INLKHRGK-C
AGRIN_CHICK/199-244R--IKVISKGP-C
AGRIN_CHICK/274-319N--VFKKFDGA-C
AGRIN_CHICK/417-462A--IPVKHSGP-C
AGRIN_CHICK/492-536E--IRVKHKGP-C
AGRIN_CHICK/557-601N--ILVAAQGD-C
AGRIN_CHICK/622-666S--IEVAKMGP-C
AGRIN_CHICK/706-751N--LYVTSQGA-C
AGRIN_CHICK/923-969L--ITVKHVGQ-C
ISK1_BOVIN/32-79P--VLIQKSGP-C
AGRIN_RAT/167-212H--IFKKFNGP-C
AGRIN_RAT/237-284L--LQKVRSGQ-C
AGRIN_RAT/311-356A--IPPKHQGP-C
AGRIN_RAT/385-429E--IQVARRGP-C
AGRIN_RAT/450-494S--LYVASAGH-C
AGRIN_RAT/515-559Q--IEEAHAGP-C
AGRIN_RAT/600-645E--LYVAAQGA-C
AGRIN_RAT/818-864D--ISTQSLGP-C
FST_HUMAN/118-164E--LEVQYQGR-C
FST_HUMAN/192-239S--IGLAYEGK-C
FST_HUMAN/270-316L--LEVKHSGS-C
IAC1_BOVIN/14-61D--IHFNHFGE-C
ISK2_HUMAN/36-84N--IKIIRNGP-C
IACA_PIG/7-57K--FDFGHWGH-C
IOV7_CHICK/28-85N--VEKEYDGE-C
IOV7_CHICK/94-150N--ISKLHDGE-C
IOV7_CHICK/159-216H--VSKKHDGK-C
IOV7_CHICK/225-282E--VKKSHDGR-C
IOV7_CHICK/356-413N--LGKRKNGR-C
IOV7_CHICK/422-472T--LNLVSMAA-C
IOVO_PIPPP/8-56T--LTLSHFGK-C
IOVO_CASCA/6-54T--LTLGHFGK-C
IOVO_CHICK/29-86N--ISKEHDGE-C
IOVO_CHICK/94-151S--VDKRHDGG-C
IOVO_COTJA/5-62N--ISKEQDGE-C
IOVO_COTJA/70-127S--VGKKHDGE-C
IOVO_EUDEL/5-51N--VTLNHIGE-C
IOVO_FRACO/5-53T--LTLSHFGK-C
ISK1_RAT/32-79S--IHIQRRGT-C
ISK3_RAT/32-79S--IRIQRRGL-C
IPSG_CANFA/12-64E--VRKLQDTA-C
IPSG_CANFA/68-115T--IFLAKHGE-C
IPSG_FELCA/8-60Q--LRKLHDNK-C
IPSG_FELCA/64-111T--LFLAKYGQ-C
IPSG_MELME/16-68S--VRILQDNN-C
ISK1_ANGAN/12-61D--ILITKDDR-C
ISK1_CANFA/10-57S--ILVEKSGP-C
ISK4_PIG/37-86D--IQIVKDGE-C
SPRL1_COTJA/468-521Q--LHLDYMGA-C
SPRL1_RAT/426-479Q--LQLDYFGA-C
SPRC_BOVIN/95-149K--LHLDYIGP-C

PF07648

SPRL1_MOUSE/448-495Q..LQLDYFGA.C
FSTL1_MOUSE/56-96K..IQVDYDGH.C
Q95011_CAEEL/330-376E..RVLVHIKS.C
Q95011_CAEEL/138-183R..IQLAEDRKFC
SO3A1_HUMAN/477-511N..STNLTGCA.C
SO5A1_HUMAN/561-603G..IRNYTECT.C
ISK5_HUMAN/721-761E..RKNEYSRS.R
ISK5_HUMAN/111-151Q..IGVKSEGE.C
ISK5_HUMAN/451-491R..ARAKAKRE.A
ISK5_HUMAN/510-551E..KKNDKEEK.G
ISK5_HUMAN/581-621K..EKERAEPR.A
ISK5_HUMAN/239-283S..KTDQNLGK.A
ISK5_HUMAN/863-905R..KKKDEEKS.S
ISK5_HUMAN/930-971E..RAKLQEKP.S
ISK5_HUMAN/175-214A..ENAKREGE.T
ISK5_HUMAN/788-833K..EDEDRSNT.G
FSTA_DANRE/277-319L..LEVKHSGS.C
ISK5_HUMAN/646-691K..EEEDQRNA.A
HTRA3_MOUSE/87-132P..VRQLQKGA.C
Q9W269_DROME/546-588G..KKIFYDCS.C
SO1A2_HUMAN/445-486I..NMVFQNCS.C
SPRC_CAEEL/80-135K..VHLEYLGE.C
ISK1_STRCA/23-63N..VRIKRRGT.C
CO6_HUMAN/793-837Q..LHFLHIGS.C
IPSG_MARMT/28-68G..VRILQDNE.C
SO4A1_HUMAN/510-553VDGQKVYRDCS.C
SO1A1_RAT/445-486T..NMVFQDCS.C
HTRA1_XENLA/91-134A..IIPIQRGD.C
Q95LZ2_MACFA/275-315E..EKKKAEAQ.A
TICN2_MOUSE/139-180Q..LAVRCEGP.C
Q9D5W6_MOUSE/486-527K..EKTYYNCS.C
TICN3_HUMAN/142-183Q..ISVKCEGH.C
Q9VUD9_DROME/298-342V..FHQVHDAE.C
Q8K4K9_RAT/491-532N..EKTYYNCS.C
FSTL3_MOUSE/123-165D..LRVMYRGR.C
SO2A1_MOUSE/449-493K..QPIYLNCS.C
HTRA3_HUMAN/81-126P..VRQLQKGA.C
CFAI_RAT/70-109E..IKFSNNGT.C
Q8UVG4_LEUER/460-501K..STEFHNCS.C
Q9VUD8_DROME/260-310D..EDVCRLGV.C
IPSG_PANLE/20-60Q..IRKLYDDK.C
LDTI_HIRME/6-40...VSIKSEGS.C
AGRIN_DISOM/214-255V..INILHQGP.C
SO1B3_HUMAN/465-506K..HTVFYNCS.C
MCPI_MELCP/101-141R..ITLDHPGE.C
THBI_RHOPR/60-101G..VELKHEGP.C
TICN1_HUMAN/139-180S..LATLCDGP.C
WFKN1_HUMAN/120-157H..LHIVP....C
Q6NW92_DANRE/91-134E..IRVHNTGR.C
RECK_HUMAN/716-750G..KSLSYKGP.C
MCPI_MELCP/53-93E..ITFDHAGP.C
RECK_HUMAN/635-671Q..DHQFEFGS.C
IACS_PIG/48-88K..FDFGHWGH.C
IOVO_MELGA/86-126S..VGKKHDGE.C
FST_PIG/122-164E..LEVQYQGK.C
HTRA4_HUMAN/108-152P..AVPVQWGN.C
IPSG_PANLE/71-111T..LFLAKYGQ.C
IBD3_HIRME/6-40...ASVAHDHA.C
SO1B2_MOUSE/460-503KLMNIEFYDCS.C
IOV7_CHICK/307-347S..VAKKHDGR.C
Q95LZ2_MACFA/345-385E..EKKKKEGK.S
Q8QGV0_CYPCA/183-222P..IFSHFSSS.C
Q9W271_DROME/470-512G..RTIYTGCE.C
IPSG_VULVU/24-64E..VRKLQDTA.C
Q8SY02_DROME/486-527S..LKRYHNCS.C
AGRIN_RAT/97-137R..IRLLRQGP.C
IPSG_MELME/79-119A..LFLAKHGQ.C
Q8T926_TETTH/32-76E..TQFVVPGN.C
SO1C1_HUMAN/482-523K..NIIFYNCT.C
FST_PIG/196-239S..IGLAYEGK.C
FST_PIG/274-316L..LEVKHSGS.C
SPRC_RABIT/103-151K..LHLDYIGP.C
Q9VP16_DROME/519-563S..VTIKSKGS.C

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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