Sequence alignment for CL0041

PF02758

NAL4E_MOUSE/6-89-------SDFGLMW-YLEELNKKEFMKFKELLQ...--------------....QEILQLGLKHISWTE--VKK.AS---
MEFV_MOUSE/5-88-------LGDHLLN-TLEELLPYDFEKFKFKLQ...--------------....NTSLEKGHSKIPRGH--MQM.AR---
NALP6_HUMAN/18-99-------ARELLLA-ALEELSQEQLKRFRHKL....--------------.....RDVGPDGRSIPWGR--LER.AD---
NAL11_HUMAN/7-87-------TDFDLLW-YLENLSDKEFQSFKKYL....--------------......ARKILDFKLPQFP--LIQ.MT---
NALP5_HUMAN/61-144-------SSYGLQW-CLYELDKEEFQTFKELLK...--------------....KKSSESTTCSIPQFE--IEN.AN---
IFI4_MOUSE/6-84-------KRIVLLR-GLECINKHYFSLFKSLL....--------------.........ARDLNLERDN--QEQ.YT---
PYDC3_MOUSE/10-88-------KQIVLLS-GLEYMNDYNFRALKSLL....--------------.........NHDLKLTKNM--QDD.YD---
IFI5A_MOUSE/6-84-------KRLVLLE-GLECINKHQFNLFKSLM....--------------.........VKDLNLEEDN--QEK.YT---
NAL13_HUMAN/13-103-------TNQGLLP-YLMALDQYQLEEFKLCLEPQQ--------------LMDFWSAPQGHFPRIPWAN--LRA.AD---
NALP9_BOVIN/7-90-------SDFGLLW-YLEELKKEEFWKFKELLK...--------------....QEPLKLKLKPIPWTE--LKK.AS---
NALP4_HUMAN/7-90-------SDFGLMW-YLEELKKEEFRKFKEHLK...--------------....QMTLQLELKQIPWTE--VKK.AS---
PYDC1_HUMAN/4-87-------KREAILK-VLENLTPEELKKFKMKLG...--------------....TVPLREGFERIPRGA--LGQ.LD---
Q5RGK3_DANRE/4-82-------VKQLLKN-SLDELREAELKEFQWCL....--------------........VNDHREISTAE--LEN.AD---
Q5RGA0_DANRE/4-82-------VKQLLKK-SLDELVEDTLKDFQWHL....--------------........MNDHREISKAE--MEN.AD---
NALP8_HUMAN/37-119-------CENGVML-YMRNVSHEELQRFKQLLL...--------------.....TELSTGTMPITWDQ--VET.AS---
MEFV_RAT/5-88-------RVDHLLN-TLEELLPYELEKFKFKLH...--------------....TTSLEKGHSRIPLSL--VKM.AR---
AIM2_HUMAN/6-83-------KEILLLT-GLDNITDEELDRFKFFL....--------------.........SDEFNIATGK--LHT.AN---
Q4SV51_TETNG/5-87-------VAKLLKD-YLEEMNDSRLSEFKWYLS...--------------.....QHKQNGCRPLQRSQ--LES.GT---
MEFV_HUMAN/5-88-------PSDHLLS-TLEELVPYDFEKFKFKLQ...--------------....NTSVQKEHSRIPRSQ--IQR.AR---
Q4VBV3_DANRE/5-86-------FKEHLQE-AFEDLGADNLRKFKSKL....--------------......GDRRQEPRVTKSA--IEKLKD---
NALP9_HUMAN/7-90-------SDFGLLW-YLKELRKEEFWKFKELLK...--------------....QPLEKFELKPIPWAE--LKK.AS---
IFIXL_MOUSE/6-83-------KRIVLLT-GLMGINDHDFRMVKSLL....--------------.........SKELKLN.KM--QDE.YD---
Q8V3S3_SWPV1/3-81-------LRYTIIS-VLERLTPYQFKTLLFLI....--------------.........QDDINISNDD--INV.LD---
Q9I9L7_DANRE/5-85-------IKDHLQD-ALSNIGADNLRRFQSRL....--------------......GDRKQEPRVRKST--IEKLKD---
NAL12_HUMAN/9-91-------GLCRLST-YLEELEAVELKKFKLYLG...--------------.....TATELGEGKIPWGS--MEK.AG---
NALP7_HUMAN/6-89-------LEWTLQT-LLEQLNEDELKSFKSLLW...--------------....AFPLEDVLQKTPWSE--VEE.AD---
NAL14_HUMAN/11-93-------PDFGLLL-YLEELNKEELNTFKLFLKE..--------------....TMEPEHGL..TPWNE--VKK.AR---
Q66JP4_MOUSE/6-89-------SDFGLMW-YLKELNKKEFIKFKEFLI...--------------....QEILKLKLKQISWTE--VKK.AS---
Q4U0E2_DANRE/4-85-------ITQLLSD-VLEDLVEAELKQFTRQLW...--------------.....IGVKPGVEPIPRGK--LEN.KD---
Q5F3J4_CHICK/5-88-------ESTILLE-ALEGLTLEDFQEFKKKLP...--------------.....HTDIKGGWNIGRDE--LEK.VT---
IF16_HUMAN/6-84-------KNIVLLK-GLEVINDYHFRMVKSLL....--------------.........SNDLKLNLKM--REE.YD---
MNDA_HUMAN/6-84-------KKILLLK-GFELMDDYHFTSIKSLL....--------------.........AYDLGLTTKM--QEE.YN---
ASC_HUMAN/4-87-------ARDAILD-ALENLTAEELKKFKLKLL...--------------....SVPLREGYGRIPRGA--LLS.MD---
Q6DJG0_XENLA/5-88-------VRDLLLE-TLEELGEKQFKKFKGKLN...--------------....DWEVNAGYKVIPKCR--LEK.AD---
Q5U2R8_RAT/6-84-------KRIVLLK-GLEPLSSHHFSLFKSLL....--------------.........ASDLKLERHM--QEQ.YT---
Q5SXI6_MOUSE/4-87-------VRCKLAQ-YLEDLEDVDLKKFKMHLE...--------------....DYPPEKGCIPVPRGQ--MEK.AD---
Q6UQE6_MOUSE/9-91-------GLYRLST-YLEELEAGELKKFKLFLG...--------------.....IAEDLSQDKIPWGR--MEK.AG---
IFI3_MOUSE/5-83-------KNIVLLK-GLENMEDYQFRTVKSLL....--------------.........RKELKLTKKM--QED.YD---

PF01335

Q9JHX4_RAT/3-86-------FHSCLYD.IAERLGNEELAALKFLCL--------------------------...DHIPQKK..QESIND---
Q9I8J3_DANRE/99-179-------YRKMLLK.ISEDMTEENFRAAKFLLD--------------------------.....LPRAK..LGRSTS---
CFLA_EHV2/2-75-------SHYSMID.TYFSLDEDETETYLYLCR--------------------------...D.LLKNK...GEFQC---
CFLA_MCV1/9-84-------SLPFLRH.LLEELDSHEDSLLLFLCH--------------------------...DAAPGCT..TVT...---
FADD_HUMAN/4-87-------FLVLLHS.VSSSLSSSELTELKFLCL--------------------------...GRVGKRK..LERVQS---
P88961_HHV8/94-170-------YQLTVLH.VDGELCARDIRSLIFLSK--------------------------...DTIGSRS..TPQ..T---
DEDD2_HUMAN/25-110-------SLHRMFEVVGGQLTECELELLAFLLD--------------------------...E.APGAAGGLARARS---
Q90WU1_CHICK/3-86-------FSQLLFV.ISEALDRTELASLKFLSL--------------------------...EHVTVRK..REDIEE---
CFLAR_HUMAN/2-79-------SAEVIHQ.VEEALDTDEKEMLLFLCR--------------------------...D.VAIDV..VPP..N---
VG71_SHV21/3-81-------LKTTVLH.ITDSFTDEEMYCLLFLIN--------------------------...GCIPRSC..NAV..N---
CASP8_MOUSE/3-86-------FQSCLYA.IAEELGSEDLAALKFLCL--------------------------...DYIPHKK..QETIED---
CFLAR_MOUSE/7-84-------SAEVIHQ.VEECLDEDEKEMMLFLCR--------------------------...D.VTENL..AAP..N---
Q8CD57_MOUSE/4-87-------FLVLLHS.LSGSLSGNDLMELKFLCR--------------------------...ERVSKRK..LERVQS---
Q99CX0_BHV4/95-177-------YKQLIFS.IGQNIDDEDLISIKFISM--------------------------...NYIGKSP...SKIKN---
CASP8_HUMAN/101-183-------YRVMLYQ.ISEEVSRSELRSFKFLLQ--------------------------...EEISKCK..LDDDMN---
CFLA_EHV2/93-170-------FRCLMAL.VNDFLSDKEVEEMYFLCA--------------------------PRLESHLEPG..SKK..S---
CFLA_MCV1/96-181-------YRKLMVC.VGEELDSSELRALRLFAC--------------------------.NLNPSLSTA..LSESSR---
O11300_MCV1/10-82-------FLRNLLA....ELDASEHEVLRFLCR--------------------------...DVAPASK..TAE...---
Q9IB62_XENLA/98-177-------YRQMLYE.LSENVTGEDEKRILFILP--------------------------......LHKK..HKENKT---
PEA15_HUMAN/4-87-------YGTLLQD.LTNNITLEDLEQLKSACK--------------------------...EDIPSEK..SEEITT---
Q9IB62_XENLA/3-86-------FNSMLLR.IDDGLGREDIEALKFLCR--------------------------...DVLRKNK..LLSVQS---
Q9JHX4_RAT/101-183-------YRVMLFK.LSEDMDKEDLKSFKFLLI--------------------------...TEIPKCK..LQDNSS---
Q9J2H2_9GAMA/94-168-------YKHLMLS.IDRQLSERDVKNLVFLTG--------------------------...DQLGRRR..NQS.PT---
Q90WU1_CHICK/101-183-------FRYLLFQ.LSENITKDDMKCFKFLLG--------------------------...KELPKCK..LSPETT---
Q9IB64_XENLA/113-193-------YRILLYD.ISQGLSKKEVEDLKYLLD--------------------------......LSTA..KTENAS---
DEDD_HUMAN/25-109-------SLHRMFDIVGTHLTHRDVRVLSFLFV--------------------------...DVIDDHE..RGLIRN---
O11300_MCV1/94-170-------YRLQVAA.INNMVGSEDLRVMC.LCA--------------------------...GKLLPPS..CTP.RC---
CASP8_HUMAN/3-86-------FSRNLYD.IGEQLDSEDLASLKFLSL--------------------------...DYIPQRK..QEPIKD---
VG71_SHV21/94-167-------HVLTLVN.VNNNLTAKDEKRLCFILD--------------------------...QFFPRNV..AAP.SV---
CFLAR_HUMAN/93-176-------YRVLMAE.IGEDLDKSDVSSLIFLMK--------------------------...DYMGRGK..ISKEKS---
Q8UVG5_DANRE/102-185-------YRVLMAD.VSENLDKEDLQSLIFLLS--------------------------...SILPKER..STRATS---
CFLAR_MOUSE/98-184-------YRVLLME.IGESLDQNDVSSLVFLTR--------------------------ITRDYTGRGK..IAKDKS---
Q8UVG5_DANRE/5-89-------FSTLVNK.VTASLSSDESKILLYLCT--------------------------...DLFNNSC..VEE..L---
CASPA_HUMAN/20-102-------FREKLLI.IDSNLGVQDVENLKFLCI--------------------------...GLVPNKK..LEKSSS---
CASP8_MOUSE/101-183-------YRVMLFK.LSEEVSELELRSFKFLLN--------------------------...NEIPKCK..LEDDLS---
Q9IB64_XENLA/17-100-------MNKLLFE.ISEDLDKTETLAMIFLCE--------------------------...KRVTAQE..KENIKD---
CASPA_HUMAN/115-193-------FRNLLYE.LSEGIDSENLKDMIFLLK--------------------------...DSLPKTE..MTS...---

PF14786

E8NH30_DROME/27-172YSRNTELRRVEDNDIYRLAKILDENSCWRKLM-SIIPKGM.DVQACSGAGCLNFP.AEIKKGFKYTAQD--VFQIDE--A
TUBE_DROVI/27-173YTRCTELRRVDDNDIYKLATILDVNGCWRKLM-SIIPKRL.DAQACSAPGALNYQEIAAKVGLKYTAQQ--ISLIDG--T
B0X4E9_CULQU/4-135YQRTTEIRKVTPFDLESLTEILEDD..WRTLF-YLIPRRIGDVDQPPGAYL...........TKYNGNQ--ERDLDK--H
Q171H8_AEDAE/4-133YTRSTEVRKVFELD..ELASVLEDD..WRTLF-YLIPRKIADVERPAGS....YP.I......RYNGTH--ESELDD--Y

PF00531

NFKB1_CHICK/816-891---------QQLYKLL.ETPDPSKN--WSTLA.EKL...------------------------GL.GIL--NNAFRL...
TNR6_MOUSE/223-306---------KYIPRIA..EDMTIQE--AKKFA.REN...------------------------NIKEGK--IDEIMH...
Q7QD54_ANOGA/47-126---------KRLAALL....EVNNK--WYELGEKQM...------------------------GYSTVE--LDSTQR...
Q7QH59_ANOGA/617-697---------AQLSEL...APSIGRD--WKKLA.TKL...------------------------GYSADE--IQYFES...
TR10B_MOUSE/273-356---------KFIFEYC.SDIVPFDS--WNRLM.RQL...------------------------GLTDNQ--IQMVKA...
TR10A_HUMAN/366-448---------LFFDKFA..NIVPFDS--WDQLM.RQL...------------------------DLTKNE--IDVVRAG.T
TR10B_HUMAN/340-422---------QCFDDFA..DLVPFDS--WEPLM.RKL...------------------------GLMDNE--IKVAKA...
DTHD1_HUMAN/679-764---------DNLLHWL.AEELSEEN--AESLS.STL...------------------------PLRRST--IQLIKL...
TR11B_MOUSE/293-365---------EQLLALM..ESLPGKK--............------------------------.ISPEE--IERTRK...
UNC5A_RAT/817-896---------QKIIASLDPPCSRGAD--WRTLA.QKL...------------------------HL.DSH--LSFFAS...
UNC5B_RAT/864-943---------QKICNSLDAPNSRGND--WRLLA.QKL...------------------------SM.DRY--LNYFAT...
TR11B_RAT/279-365---------SSVQRHIGHANLTTEQ--LRILM.ESLPGK------------------------KISPDE--IERTRKT.C
UNC5C_MOUSE/850-929---------QKLCSSLDAPQTRGHD--WRMLA.HKL...------------------------NL.DRY--LNYFAT...
TNR1A_BOVIN/373-457---------ATLYAVV..DGVPPSR--WKELV.RRL...------------------------GLSEHE--IERLEL...
IRAK2_HUMAN/14-94---------DDLCRNM..DALSEWD--WMEFA.SYV...------------------------ITDLTQ--LRKIKS...
DAPK_CAEEL/1307-1389---------CELACLLDPPHAMGRD--WSILA.VKL...------------------------QL.TDQ--VPDVDST.G
O57408_MELGA/275-357---------SSFNTFV..DLVPFPQ--WRRFG.RAL...------------------------GLRENN--LYQAEQN.D
O70510_RAT/13-96---------DIRMAIV..ADHLGLS--WTELA.REL...------------------------NFSVDE--INQIRV...
NFKB2_XENLA/826-901---------QRLEKLL.NEGQTGAD--WTELA.SRL...------------------------RL.QSL--VETYKN...
TNR21_HUMAN/416-498---------IDILKLV..AAQVGSQ--WKDIY.QFL..C------------------------NASERE--VAAFSN...
TNR6_PIG/228-311---------KYITRIA..EQMKITE--VKDFV.RKN...------------------------GIEETK--IDEIMH...
CRADD_MOUSE/117-198---------DQQINQL..AQRLGPE--WEPVV.LSL...------------------------GLSQTD--IYRCKA...
O96407_LITSI/145-224---------LSLPHV...ARLIGAD--WHRLA.RAL...------------------------EVPDID--IRQVRH...
O96458_STRPU/1012-1088---------EKLGSMLDDNYPTTQS--WFTLA.NRL...------------------------GL.SNM--LNFLKL...
ANK1_HUMAN/1404-1487---------EMKMAVI..SEHLGLS--WAELA.REL...------------------------QFSVED--INRIRV...
TNR16_CHICK/334-410---------EEVEKLL..SSSAEET--WRQLA.GEL...------------------------GYKEDL--IDCFTR...
NFKB1_HUMAN/817-892---------LQLYKLL.EIPDPDKN--WATLA.QKL...------------------------GL.GIL--NNAFRL...
TNR1A_RAT/364-448---------AMLYAVV..DGVPPTR--WKEFM.RLL...------------------------GLSEHE--IERLEL...
THOC1_RAT/249-331---------GERIESL..TNKLDEQ--WKILA.PYL...------------------------EIKDSD--IRQIEC...
NFKB2_CHICK/783-857---------QGLEQLL.NQYGSGSD--WMELA.KRL...------------------------GL.CSL--VETYKT...
NFKB2_HUMAN/776-851---------QNLEQLL.DGPEAQGS--WAELA.ERL...------------------------GL.RSL--VDTYRQ...
KPEL_DROME/43-121---------AQLCAHL....DALDV--WQQLA.TAV...------------------------KLYPDQ--VEQISSQ.K
FADD_HUMAN/98-181---------CAAFNVI..CDNVGKD--WRRLA.RQL...------------------------KVSDTK--IDSIED...
RIPK1_HUMAN/584-669---------DKHLDPI..RENLGKH--WKNCA.RKL...------------------------GFTQSQ--IDEIDHD.Y
Q24241_DROME/1442-1526---------DVILDDI..CSHLGSD--WPLLA.NVL...------------------------GVSQAD--IDLVKT...
UNC5_CAEEL/828-910---------DELARLLDMPNESHSD--WRGLA.KKL...------------------------HY.DRY--LQFFASF.P
MYD88_DANRE/23-101---------KKLGLFLNPTNTVAAD--WRTVA.ELM...------------------------DFTYLE--IKNFEK...
Q61304_MOUSE/1001-1084---------EMRMAVI..REHLGLS--WAELA.REL...------------------------QFSVED--INRIRV...
TNR6_RAT/220-303---------KYIWRTA..EKMKICD--AKKFA.RQH...------------------------KIPESK--IDEIEH...
Q6DIU6_XENTR/20-97---------YRFFHIM..DSLEETD--WKKFA.SMI...------------------------IPDMTE--LRLLEQQ.G
Q6DJ38_XENTR/115-196---------EKQLNLL..AGKLGPE--WEQIL.VHL...------------------------GLDHND--LYRCKE...
Q6DJ81_XENTR/230-311---------QTWDLFV..EHVPMEK--WAQFM.RSL...------------------------RLSDNT--VWEAKE...
Q6E5U7_ICTPU/222-303---------PKISEIL..GVRVILQ--VVRQQ.RL....------------------------.LSEGV--IDNITV...
Q6GLZ4_XENLA/237-318---------RSWDHFF..EHVPMER--WDQFM.RNL...------------------------HISANT--VYEAKE...
Q6JA22_XENLA/305-382---------SEVERLL.ADTSLGKD--WQRLA.SLL...------------------------GYEEET--IDTLGR...
Q6K198_DANRE/796-869---------SKLCGIL..IHGDVP.--WRELA.EKL...------------------------GM.LTL--THLYQD...
Q6NRK5_XENLA/1308-1393---------RKLSRLLDPPDPMGKD--WCLLA.MNL...------------------------GLPDLV--AKYNTNN.S
Q6Q782_ICTPU/100-183---------NCAIEVI..SEQLGRK--WIKYG.RKL...------------------------KIAETK--LEGIQE...
UN5CL_MOUSE/414-491---------EQLQMLLEPNSVTGND--WRRLA.SHL...------------------------GLCGMK--IRFLSC...
Q76B98_XENLA/237-318---------RSWDHFV..DQVPTPK--WDQFM.RTL...------------------------CLSPIS--VSEAKE...
Q7KU92_DROME/1420-1501---------DIRIVDL..SNLLGKD--WIQLA.PEI...------------------------GINGEE--IDEIIN...
Q7PT80_ANOGA/1055-1127---------EELCRLL....DAGSG--WRELG.SLL...------------------------DF.HSF--FTVWEQ...
Q7SYB2_DANRE/574-655---------NSQMDEI..AAKLGSQ--WKTLA.DHL...------------------------EMSDKE--IRVIESD.S
Q7T3M8_CHICK/322-403---------DCFFAFI..KEVPVKK--WRKLM.RT....------------------------HLEEND--IDKIIY...
Q7ZXL7_XENLA/573-655---------SEQIESF..ANKLGEH--WKTLA.PYL...------------------------DMKDLD--IKMIESD.T
Q7ZYE4_XENLA/22-101---------DEFCRCM..DSLSDWE--WMRFA.SSV...------------------------IDDQTV--LRRIRSY.E
Q7ZZX8_CHICK/576-661---------KKQLSLV..RENLGKQ--WKHCA.REL...------------------------GFSNSV--IEEIDHD.Y
Q800K8_PAROL/304-384---------KKCFELF..EEIEFDQ--HKRFF.RHL...------------------------GISDNV--IKSKELD.H
DAPK1_MOUSE/1311-1396---------RKLSRLLDPPDPMGKD--WCLLA.MNL...------------------------GLPDMV--AKHNVNN.R
Q861W6_FELCA/225-308---------KYISSIA..EQMKITQ--VREFV.RKN...------------------------GINEAK--IDEIKN...
Q8BR10_MOUSE/28-103---------CRFYKVM..DALEPAD--WCQFA.ALI...------------------------VRDQTE--LRLCER...
Q8BY25_MOUSE/116-192---------DTIRIKLDPCHPTVKN--WRNFA.SKW...------------------------GMPYDE--LCFLEQ...
Q8BYY1_MOUSE/338-411---------EEVEKLL.....NGDT--WRHLA.GEL...------------------------GYQPEH--IDSFTH...
Q8C1X0_MOUSE/31-109---------RRLSLFLNPRTPVAAD--WTLLA.EEM...------------------------GFEYLE--IRELET...
ANK2_MOUSE/3523-3606---------EERLAYI..ADHLGFS--WTELA.REL...------------------------DFTEEQ--IHQIRI...
Q8CD57_MOUSE/98-181---------QVAFDIV..CDNVGRD--WKRLA.REL...------------------------KVSEAK--MDGIEE...
NRADD_MOUSE/143-222---------EEVQRLL.MMGEPAKG--WQELA.GHL...------------------------GYQAEA--VETMAC...
Q8IUB6_HUMAN/5-88---------KYITTIA..GVMTLSQ--XKGFV.RKN...------------------------GVNEAK--IDEIKN...
UNC5D_MOUSE/862-939---------QRICATFDTPNAKGKD--WQMLA.QKN...------------------------SI.NRN--LSYFAT...
IRAK3_MOUSE/26-106---------GELCGIL.DSCDGPLG--WRGLA.ERL...------------------------SNSWLD--VRHIEKY.V
Q8MQG0_CAEEL/1498-1578---------EFVHQNV..LKGIGAD--WPRLG.RAL...------------------------EVPHRD--IQHIRQ...
Q8MV43_AEDAE/578-650---------SHLCGLL....NRKNL--WREVG.SLL...------------------------DF.NSF--FMIWET...
Q8VD70_MOUSE/303-383---------PQLYDVM..DAVPARR--WKEFV.RTL...------------------------GLREAE--IEAVEVE.I
EDAD_MOUSE/116-192---------DTIRIKLDPCHPTVKN--WRNFA.SKW...------------------------GMPYDE--LCFLEQ...
EDAR_ORYLA/403-476---------RMLSSSYSSDAAVVKT--WRHLA.ESF...------------------------GLKRDE--IGGM.....
MYD88_HUMAN/31-109---------RRLSLFLNVRTQVAAD--WTALA.EEM...------------------------DFEYLE--IRQLET...
Q9BDP0_AOTTR/226-309---------KYITVIA..EHMTISQ--VRDFV.RKN...------------------------GVNEAK--IDEIKN...
Q9DF34_DANRE/266-346---------KKTFDFF..EEIDVHY--HNRFF.RLI...------------------------GLSDNA--IKSAES...
MY88A_XENLA/26-105---------HRLCLYLNPDAVVAAD--WTRLA.EEM...------------------------GYDYLE--IRNFQR...
Q9DFV0_DANRE/349-429---------SKSFDLF..DSLDVRY--HNKFF.RSI...------------------------GVSDNS--IKLAET...
Q9DGH7_CHICK/153-236---------HHVPDIV..REMTLEQ--VMTFV.RHH...------------------------RLSEPT--IEETLL...
AND1A_MACFA/379-467---------SVLWRLA.SRHLQPRE--WKKLA.YSW...------------------------DFTEAH--VYAIEQQ.W
Q9IAR7_CHICK/275-357---------RSFNTFV..DYVPFPE--WKRFG.RAL...------------------------DLQEND--LYLAEQ...
Q9N9X2_GEOCY/23-103---------DHLTEI.....KEFIP--WKKVGPRLK...------------------------GISDGD--IDDIDRDGF
Q9NHG0_DROME/203-289---------VRLLDVV..STHLGEG--WKQVM.RDL...------------------------GMSEGQ--IDQAIID.H
Q9PRG7_XENLA/319-395---------EEVEKLL..SGSLEQT--WKSLA.GEL...------------------------GYQDEI--IDSFTR...
BG4_DROME/152-237---------TMVFKKI..SEELGRY--WRRLG.RSA...------------------------GIGEGQ--MDTIEE...
Q9VNI8_DROME/607-687---------EHIEEV...APLIGEP--WMKVG.KKI...------------------------GFTNDE--LLFFQM...

PF00619

CASP4_MOUSE/3-90-ENKHPDKPLKVLEQLGKEVLTE...YLEKLVQSNV----------------------------LKLKE--EDKQKF..N
BIRC3_MOUSE/441-524-LALIRKNKMVLFQHLT..CVTP...MLYCLLSARA----------------------------ITEQE--CNAVKQ...
VCLAP_EHV2/26-110-RLCLEELRVLLVSHLK...SHK...HLDHLRAKKI----------------------------LSRED--AEEVSS...
CASP5_HUMAN/61-147-KDNHKKKTVKMLEYLGKDVLHG...VFNYLAKHDV----------------------------LTLKE--EEKKKY..Y
CAR14_HUMAN/20-106-WEMMESHRHRIVRCIC...PSR...LTPYLRQAKV----------------------------LCQLD--EEEVLHSPR
CAR11_MOUSE/23-109-WDNVECNRHMLSRYIN...PAK...LTPYLRQCKV----------------------------IDEQD--EDEVLNAPM
IFIH1_HUMAN/115-200-LQLLNLLQPTLVDKLL...VRD...VLDKCMEEEL----------------------------LTIED--RNRIAAA.E
Q80UH6_MUSMC/8-94-QAQRSQLVALLISGSL.EGFES...ILDWLLSWDV----------------------------LSRED--YEGLSL..P
Q7ZXD2_XENLA/10-94-RKALQRLRVSLASEMI...IEE...LLDHLVSSEI----------------------------LTNNM--HSNIMA...
NALP1_HUMAN/1379-1462-LHFVDQYREQLIARVT..SVEV...VLDKLHGQ.V----------------------------LSQEQ--YERVLA...
CAR14_MOUSE/20-106-WDMLESHRCRIVQSIC...PSR...LTPYLRQAKV----------------------------LGQLD--EEEILH..S
APAF_DANRE/6-90-RSRLLRSKATLEQDIK...ASY...LMDHMISDGV----------------------------LTNDE--EAKVLS...
APAF_HUMAN/6-90-RNCLLQHREALEKDIK...TSY...IMDHMISDGF----------------------------LTISE--EEKVRN...
Q9Y1U6_PRIPA/7-91-NEHRKALIGFGDSSLPPLYLDP...ILDYLEVKQV----------------------------LPESK--INEIRR...
CASP2_RAT/37-121-QETLKKNRVVLAKQLL...LSE...LLEHLLEKDI----------------------------ITLEM--RELIQA...
Q6YH84_9VIRU/6-93-AQKIRKGRLAFVRLSKLETLQN...LIDEMLAERV----------------------------FNEGQ--AADILE..S
CASP1_HUMAN/3-90-DKVLKEKRKLFIRSMGEGTING...LLDELLQTRV----------------------------LNKEE--MEKVKR..E
Q80UH2_MUSSP/104-191-TRDLQSHRPAIVRRLY.NHVEA...MLELARERGF----------------------------LSQYE--CEEIRL..P
Q8JFQ3_CYPCA/17-103-WARLEDYRMLLIKTIE...PSR...ITPYLRQCKV----------------------------LSSED--EEQIYN...
ASC_HUMAN/112-195-LHFIDQHRAALIARVT..NVEW...LLDALYGK.V----------------------------LTDEQ--YQAVRA...
CASP1_CANFA/3-90-DKVLKDKRRLFVRSVDMGTING...LLDELFEKRV----------------------------LNHEE--MERVRC..A
CRADD_MOUSE/6-89-KQVLRSLRLELGAEVLVEGL.....VLQYLYQEGI----------------------------LTENH--IQEIKA...
Q6ZM93_DANRE/494-578-FTFLKKHHAALSQRLK..SVQS...LMDHLLEENV----------------------------ISQKE--YDSIRN...
RIPK2_HUMAN/437-524-QQWIQSKREDIVNQMTEACLNQ...SLDALLSRDL----------------------------IMKED--YELVST...
BIRC2_HUMAN/458-542-LSLIRKNRMALFQQLT..CVLP...ILDNLLKANV----------------------------INKQE--HDIIKQ...
CASP1_PIG/3-90-DKVLKEKRRLFVRSVAMGTING...LLDELLETRV----------------------------LNQEE--VEIVRG..E
CED3_CAERE/7-91-RSLLERNILVFSNKLQ...SEQ...ILDVLIAKDV----------------------------LNSDN--GDMINS...
Q8C3Q9_MOUSE/6-92-RQLLRRCRVRLVSELQ...VAE...LWDALLSREL----------------------------FTRDM--IEDIQQA.G
NOL3_HUMAN/9-96-SETIDRERKRLV.ETLQADSGL...LLDALLARGV----------------------------LTGPE--YEALDA...
CASPD_BOVIN/3-90-EDKHNKNPLKMLESLGKELISG...LLDDFVEKNV----------------------------LKLEE--EEKKKI..Y
ASC_BOVIN/112-195-LHFVDQHRAALIARVT..VVDG...VLDALYGK.V----------------------------LTEEQ--YQAVRA...
NOD1_MOUSE/20-105-IKLLKINREHLVTNIR..NTQC...LVDNLLENGY----------------------------FSAED--AEIVCA...
CASP1_FELCA/3-90-DKVLKGKRKQFINSVGMGTVNG...LLDELFEKNV----------------------------LNQEE--MERVKC..E
BIR_CHICK/451-535-LSLIRKNRMALFQRLT..SVLP...ILGSLLSAKV----------------------------ITELE--HDVIKQ...
BCL10_HUMAN/18-102-KDALENLRVYLCEKII...AER...HFDHLRAKKI----------------------------LSRED--TEEISC...
CED3_CAEEL/7-91-RSLLERNIMMFSSHLK...VDE...ILEVLIAKQV----------------------------LNSDN--GDMINS...
Q8JHU4_DANRE/470-557-ARWIAARREEVVRQMTEACLNQ...SLDALLSREL----------------------------LMRED--YELVVN...
Q8I6Y2_GEOCY/9-92-DSALRKLTPVFQRQLA...AKD...VRHDLYGRDQ----------------------------LTWNE--YERIGV...
CASPC_MOUSE/4-91-RRTHERDPIYKIKGLAKDMLDG...VFDDLVEKNV----------------------------LNGDE--LLKIGE..S
NLRC4_HUMAN/1-87-MNFIKDNSRALIQRMGMTVIKQ...ITDDLFVWNV----------------------------LNREE--VNIICC...
Q8K4I9_MERUN/3-90-DATLRSKRTKFINSVDGGIING...LLDELLEKRV----------------------------LNEEE--MERIKA..E
CASP2_CHICK/12-96-QEALKKNRVMLARELV...LKE...LMEHMIEKDI----------------------------ITIEM--VEMIQA...
ASC_DANRE/117-202-VNFIDEHWKELIDRVN..NVDP...ILDILRQKKV----------------------------ITNED--YCTIRN...
CAR10_MOUSE/28-114-WERIEGVRHRLTRALN...PAK...LTPYLRQCRV----------------------------LDEQD--EEEVLS..T
NOD2_HUMAN/31-121-QEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEV----------------------------LSWED--YEGFHL...
CARD8_HUMAN/345-429-AAFVKENHRQLQARMG..DLKG...VLDDLQDNEV----------------------------LTENE--KELVEQ...
Q6XZE5_HUMAN/8-93-SEIIERERKKLL.EILQHDPDS...ILDTLTSRRL----------------------------ISEEE--YETLEN...
O95601_HUMAN/3-90-EGNHRKKPLKVLESLGKDFLTG...VLDNLVEQNV----------------------------LNWKE--EEKKKY..Y
Q8CHK8_RAT/110-193-EHFVDQHRQALIARVT..KVDG...LLDALYGN.V----------------------------LTEGQ--YQAVRA...
ASC_MOUSE/110-193-GHFVDQHRQALIARVT..EVDG...VLDALHGS.V----------------------------LTEGQ--YQAVRA...
CAR18_HUMAN/3-90-DQLLRKKRRIFIHSVGAGTINA...LLDCLLEDEV----------------------------ISQED--MNKVRD..E
PIAP_PIG/198-282-LSLIRKNRMALFQHLT..CVLP...ILDSLLIARV----------------------------ISEQE--HDVIKQ...
CASP1_MOUSE/3-90-DKILRAKRKQFINSVSIGTING...LLDELLEKRV----------------------------LNQEE--MDKIKL..A
IFIH1_MOUSE/115-200-LHLLTLLQPTLVDKLL...IND...VLDTCFEKGL----------------------------LTVED--RNRISAA.G
CED4_CAEEL/7-90-CRALSTAHTRLIHDFE...PRD...ALTYLEGKNI----------------------------FTEDH--SELISK...
CAS1A_XENLA/2-89-TAQLNKVRRAIIDGCNPAMISD...LLDDLREKNV----------------------------LVDSE--VEHIKE..S
CASPC_HUMAN/4-91-EKPSNGVLVHMVKLLIKTFLDG...IFDDLMENNV----------------------------LNTDE--IHLIGK..C
Q9IB63_XENLA/6-90-RDILRRNRVRLVQSLQ...VKE...LWDLLVERGV----------------------------FSNDM--IEEIQR...
Q80VR5_MOUSE/6-90-RNCLLQHREALEKDIK...TSY...IMDHMISNGV----------------------------LSVIE--EEKVKS...
CASP9_HUMAN/6-92-RRLLRRCRLRLVEELQ...VDQ...LWDALLSREL----------------------------FRPHM--IEDIQRA.G

PF02758

NAL4E_MOUSE/6-89-----------.RE--DLAN-LLLK--HYEEKKAW----DMTFKIFQKMNRQ.DLMER-AGR------------------
MEFV_MOUSE/5-88-----------.PV--KLAS-LLIT--YYGEEYAV----RLTLQILRATNQR.QLAEE-LRK------------------
NALP6_HUMAN/18-99-----------.AV--DLAE-QLAQ--FYGPEPAL----EVARKTLKRADAR.DVAAQ-LQE------------------
NAL11_HUMAN/7-87-----------.KE--ELAN-VLPI--SYEGQYIW----NMLFSIFSMMRKE.DLCRK-IIG------------------
NALP5_HUMAN/61-144-----------.VE--CLAL-LLHE--YYGASLAW----ATSISIFENMNLR.TLSEK-ARD------------------
IFI4_MOUSE/6-84-----------.TI--QIAN-MMEE--KFPADSGL----GKLIEFCEEVPALRKRAEI-LKK------------------
PYDC3_MOUSE/10-88-----------.RI--KIAD-LMEE--KFPEDAGL----SKLIEVCEDIPELAARVDI-LRK------------------
IFI5A_MOUSE/6-84-----------.TF--QIAN-MMVK--KFPADAGL----DRLINFCERVPTLKKRAEI-LKK------------------
NAL13_HUMAN/13-103-----------.PL--NLSF-LLDE--HFPKGQAW----KVVLGIFQTMNLT.SLCEK-VRA------------------
NALP9_BOVIN/7-90-----------.RE--NVSK-LLSK--HYPGKLAW----DVTLNLFLQISRD.DLWRK-ARN------------------
NALP4_HUMAN/7-90-----------.RE--ELAN-LLIK--HYEEQQAW----NITLRIFQKMDRK.DLCMK-VMR------------------
PYDC1_HUMAN/4-87-----------.IV--DLTD-KLVA--SYYEDYAA----ELVVAVLRDMRML.EEAAR-LQR------------------
Q5RGK3_DANRE/4-82-----------.RL--KTVD-KLVS--CFKPERAL----KTTVDTLRKIKQN.ELAEE-LEN------------------
Q5RGA0_DANRE/4-82-----------.RR--NTVD-KLVS--CFGSERAV----KITVDTLRKLNQN.QLAED-LEN------------------
NALP8_HUMAN/37-119-----------.WA--EVVH-LLIE--RFPGRRAW----DVTSNIFAIMNCD.KMCVV-VRR------------------
MEFV_RAT/5-88-----------.PI--KLTR-LLLT--YYGEEYAV----RLTLQILRATNQR.QLAEE-LHK------------------
AIM2_HUMAN/6-83-----------.RI--QVAT-LMIQ--NAGAVSAV----MKTIRIFQKLNYM.LLAKR-LQE------------------
Q4SV51_TETNG/5-87-----------.RT--DTVD-QLVQ--TFGEDGAL----VVAVDILYRMGLN.HLATK-LAQ------------------
MEFV_HUMAN/5-88-----------.PV--KMAT-LLVT--YYGEEYAV----QLTLQVLRAINQR.LLAEE-LHR------------------
Q4VBV3_DANRE/5-86-----------.EI--DLAD-LMVG--VFTSKDAV----SVTVEILRAIKCI.AVADD-LLR------------------
NALP9_HUMAN/7-90-----------.KE--DVAK-LLDK--HYPGKQAW----EVTLNLFLQINRK.DLWTK-AQE------------------
IFIXL_MOUSE/6-83-----------.RV--KIAD-LMED--KFPKDAGV----VQLIKLYKQIPGLGDIANK-LKN------------------
Q8V3S3_SWPV1/3-81-----------.RV--DLAI-KIMN--KYNNYRAI----YFLYKVILRIHNTEYISGT-LQR------------------
Q9I9L7_DANRE/5-85-----------.EI--DLVD-LLVN--TFTSD.AV----SVTVDILRGIKCN.AVAEE-LLE------------------
NAL12_HUMAN/9-91-----------.PL--EMAQ-LLIT--HFGPEEAW----RLALSTFERINRK.DLWER-GQR------------------
NALP7_HUMAN/6-89-----------.GK--KLAE-ILVN--TSSENWIR----NATVNILEEMNLT.ELCKM-AKA------------------
NAL14_HUMAN/11-93-----------.RE--DLAN-LMKK--YYPGEKAW----SVSLKIFGKMNLK.DLCER-AKE------------------
Q66JP4_MOUSE/6-89-----------.RE--DLAN-LLLK--CYEENQAW----DMTFNILQKINRK.DLTER-ATE------------------
Q4U0E2_DANRE/4-85-----------.RQ--DVVD-SMVQ--QYSED.AG----TITVQTLRKIKQN.ERAKR-LES------------------
Q5F3J4_CHICK/5-88-----------HPS--SLIS-YMGD--SYREGAAM----DIAISLFEEMNQR.DLAEK-ILD------------------
IF16_HUMAN/6-84-----------.KI--QIAD-LMEE--KFRGDAGL----GKLIKIFEDIPTLEDLAET-LKK------------------
MNDA_HUMAN/6-84-----------.RI--KITD-LMEK--KFQGVACL----DKLIELAKDMPSLKNLVNN-LRK------------------
ASC_HUMAN/4-87-----------.AL--DLTD-KLVS--FYLETYGA----ELTANVLRDMGLQ.EMAGQ-LQA------------------
Q6DJG0_XENLA/5-88-----------.ED--DVAD-LIIS--FYAETYGI----EVTLGVLEAIGEM.KHHGK-LRK------------------
Q5U2R8_RAT/6-84-----------.KV--QIAD-MMED--EFPDDAGL----GKFIKFCEDLPALRKRAEI-LKR------------------
Q5SXI6_MOUSE/4-87-----------.HL--DLAT-LMID--FNGEEKAW----AMAVWIFAAINRR.DLWEK-AKK------------------
Q6UQE6_MOUSE/9-91-----------.PL--EMAQ-LMVA--HMGTREAW----LLALSTFQRIHRK.DLWER-GQG------------------
IFI3_MOUSE/5-83-----------.RI--QLAD-WMED--KFPKDAGL----DKLIKVCEHIKDLKDLAKK-LKT------------------

PF01335

Q9JHX4_RAT/3-86-----------VLV--LFQR.LQEE--GMLEEDNL....SFLKELLFHISRR-DLLSR-VLKSSPEEM------------
Q9I8J3_DANRE/99-179-----------FLD--ALIE.MEKQ--QRLGPDNL....DELYRILEKCD.K-QLAVM-IERFRNQSH------------
CFLA_EHV2/2-75-----------TRD--AFKF.LSDY--ACLS...A....ANQMELLFRVGRL-DLIR.-....RIFGQ------------
CFLA_MCV1/9-84-----------..Q--ALCS.LSQQ--RKLT...L....AALVEMLYVLQRM-DLLKS-RFGLSKEGA------------
FADD_HUMAN/4-87-----------GLD--LFSM.LLEQ--NDLEPGHT....ELLRELLASLRRH-DLLRR-VDDFEAGAA------------
P88961_HHV8/94-170-----------FLH--WVYC.MENL--DLLGPTDV....DALMSMLRSLSRV-DLQR.-....QVQTL------------
DEDD2_HUMAN/25-110-----------GLE--LLLE.LERR--GQCDESNL....RLLGQLLRVLARH-DLLPH-LARKRRRPV------------
Q90WU1_CHICK/3-86-----------PKA--FFQA.LQEK--GMIEVGDL....FFLKELLYRINRI-DLLAS-YLGSSREEM------------
CFLAR_HUMAN/2-79-----------VRD--LLDI.LRER--GKLS...V....GDLAELLYRVRRF-DLLKR-ILKMDRKAV------------
VG71_SHV21/3-81-----------ISD--LIIETLSKS--TQWD...I.....CLMQCLYVLRKI-GLLLN-LFQVTKEAV------------
CASP8_MOUSE/3-86-----------AQK--LFLR.LREK--GMLEEGNL....SFLKELLFHISRW-DLLVN-FLDCNREEM------------
CFLAR_MOUSE/7-84-----------VRD--LLDS.LSER--GQLS...F....ATLAELLYRVRRF-DLLKR-ILKTDKATV------------
Q8CD57_MOUSE/4-87-----------GLD--LFTV.LLEQ--NDLERGHT....GLLRELLASLSRH-DLLQR-LDDFEAGTA------------
Q99CX0_BHV4/95-177-----------YLD--WVRA.LEKV--AMVGPDNL....DLFETLFKQIHRM-DIVKM-IKNYRTRET------------
CASP8_HUMAN/101-183-----------LLD--IFIE.MEKR--VILGEGKL....DILKRVCAQIN.K-SLLKI-INDYEEFSK------------
CFLA_EHV2/93-170-----------FLR--LASL.LEDL--ELLGGDKL....TFLRHLLTTIGRA-DLVK.-......NLQ------------
CFLA_MCV1/96-181-----------FVE--LVLA.LENV--GLVSPSSV....SVLADMLRTLRRL-DLCQQ-LVEYEQQEQ------------
O11300_MCV1/10-82-----------..D--ALRA.LQRR--RLLT...L....SSMAELLCALRRF-DVLKV-RFGMTRECA------------
Q9IB62_XENLA/98-177-----------FLD--VLCQ.LEKE--NAITEDNV....KLLEEVFRKVS.P-DLLKI-IEKYKERGD------------
PEA15_HUMAN/4-87-----------GSA--WFSF.LESH--NKLDKDNL....SYIEHIFEISRRP-DLLTM-VVDYRTRVL------------
Q9IB62_XENLA/3-86-----------GHE--LFQQ.LMTE--DLINEDNY....FLLGELLYIINHH-SLLHD-LGTNKVEVQ------------
Q9JHX4_RAT/101-183-----------LLD--IFVE.MEKR--TILAENNL....VTLKSICFRVN.R-SLLGR-IDDYERSST------------
Q9J2H2_9GAMA/94-168-----------FFR--WLSQ.MEKA--ALVSPSNY....MVLSDLLQAVSRR-DVAK.-.......VV------------
Q90WU1_CHICK/101-183-----------MPD--VFIE.MEKK--GILKEDNL....TVLKTICGKVD.K-SLLKK-IEDYELNLL------------
Q9IB64_XENLA/113-193-----------ILE--IFLE.LEKV--GKLHPDDL....QKLKHDLETIGCK-NLSRN-IEDYERISE------------
DEDD_HUMAN/25-109-----------GRD--FLLA.LERQ--GRCDESNF....RQVLQLLRIITRH-DLLPY-VTLKRRRAV------------
O11300_MCV1/94-170-----------LVD--LVSA.LEDV--GAISPQDV....SVLVTLLHAVCRY-DLSV.-....ALSAV------------
CASP8_HUMAN/3-86-----------ALM--LFQR.LQEK--RMLEESNL....SFLKELLFRINRL-DLLIT-YLNTRKEEM------------
VG71_SHV21/94-167-----------ILC--VFSN.MLCE--MHVL.ECL....CQLKKCLKQIGRS-DLAK.-.......TV------------
CFLAR_HUMAN/93-176-----------FLD--LVVE.LEKL--NLVAPDQL....DLLEKCLKNIHRI-DLKTK-IQKYKQSVQ------------
Q8UVG5_DANRE/102-185-----------FLD--VVVE.LEKL--NEVSCEKL....DFLEKCLKNIRRN-DLVKK-IQAYRNRGQ------------
CFLAR_MOUSE/98-184-----------FLD--LVIE.LEKL--NLIASDQL....NLLEKCLKNIHRI-DLNTK-IQKYTQSSQ------------
Q8UVG5_DANRE/5-89-----------RGD--LLAF.AQQN--PNQA.GQPHSGNALLMELMFQMKRY-DLLRK-VFGTNKQQV------------
CASPA_HUMAN/20-102-----------ASD--VFEH.LLAE--DLLSEEDP....FFLAELLYIIRQK-KLLQ.-HLNCTKEEV------------
CASP8_MOUSE/101-183-----------LLE--IFVE.MEKR--TMLAENNL....ETLKSICDQVN.K-SLLGK-IEDYERSST------------
Q9IB64_XENLA/17-100-----------AKT--LFLC.LKKK--DLICYNDL....SFLKELLYRIGRN-DLLRG-KLGVRTEEI------------
CASPA_HUMAN/115-193-----------.LS--FLAF.LEKQ--GKIDEDNL....TCLEDLCKTVV.P-KLLRN-IEKYKREKA------------

PF14786

E8NH30_DROME/27-172ANRLPPDQSK-SQM--MIDE-WKTS-GKLNERPTV----GVLLQLLVQAELF-SAADF-VALDFLNESTPARPVDGPGAL
TUBE_DROVI/27-173AERLTPGQSI-SQV--MIDE-WKTS-GKLNERPTV----GVLLQLLVHAEIY-SAADF-VALHFLNEPKPERPTDGPAAH
B0X4E9_CULQU/4-135AS...QERRC-ALQ--LLEE-WGSS-GKLQDRPTL----EHLLKLLVKGNMF-RAADE-VAVNLLKEDPPARPQSGPAAR
Q171H8_AEDAE/4-133G.RI.QNTAR-ARI--LLEE-WGTS-GRKGERPTL----GHLYTLVDKGGMI-RAVRH-IE.KLLKVPESAQPDSGPAAP

PF00531

NFKB1_CHICK/816-891SP......SP-SKT--LLDN-YKIS......GGTV----QELIAALTQMDHT-EAIEV.IQKAL----------------
TNR6_MOUSE/223-306DSI.QDTAEQ-KVQ--LLLC-WYQS...HGKSDAY----QDLIKGLKKAECR-RTLDK.FQDMV----------------
Q7QD54_ANOGA/47-126CCQ.RNNRSP-AEQ--LLDK-WGNY......NHTI----TELFVVLSREKLY-NCMEL.IKRYV----------------
Q7QH59_ANOGA/617-697EHA.T.VADQ-CCH--LLTL-WFDD....DMDASL----DNLAYILEGLDMI-PAADA.VKQMI----------------
TR10B_MOUSE/273-356ETL.V.TREA-LYQ--MLLK-WRHQ...TGRSASI----NHLLDALEAVEER-DAMEK.IEDYA----------------
TR10A_HUMAN/366-448AGP.G...DA-LYA--MLMK-WVNK...TGRNASI----HTLLDALERMEER-HAREK.IQDLL----------------
TR10B_HUMAN/340-422EAA.G.HRDT-LYT--MLIK-WVNK...TGRDASV----HTLLDALETLGER-LAKQK.IEDHL----------------
DTHD1_HUMAN/679-764KNP.DDLTEQ-IHE--FLCF-WKKS..LPTFTDKL----RLLARHLRKIGRS-DLAEE.LKFKW----------------
TR11B_MOUSE/293-365TC...KSSEQ-LLK--LLSL-WRIK...NGDQDTL----KGLMYALKHLKTS-HFPKT.VTHSL----------------
UNC5A_RAT/817-896KP......SP-TAM--ILNL-WEAR...HFPNGNL----GQLAAAVAGLGQP-DAGLF.TVSEA----------------
UNC5B_RAT/864-943KA......SP-TGV--ILDL-WEAR...QQDDGDL----NSLASALEEMGKS-EMLVA.MTTDG----------------
TR11B_RAT/279-365KPS.....EQ-LLK--LLSL-WRIK...NGDQDTL----KGLMYALKHLKAY-HFPKT.VTHSL----------------
UNC5C_MOUSE/850-929KS......SP-TGV--ILDL-WEAQ...NFPDGNL----SMLAAVLEEMGRH-ETVVS.LAAEG----------------
TNR1A_BOVIN/373-457ENG.RHLREA-QYS--MLAA-WRRR..TPRREATL----ELLGRVLRDMDLL-GCLEN.IEEAL----------------
IRAK2_HUMAN/14-94MER.VQGVSI-TRE--LLWW-WGMR......QATV----QQLVDLLCRLELY-RAAQI.ILNWK----------------
DAPK_CAEEL/1307-1389QSL.....SR-TDQ--LLNE-WAIH...HPEQASV----GNLCRILVELGRC-DARDA.LYRTV----------------
O57408_MELGA/275-357RES.G...EP-LYQ--MLIM-WLNK...EGSKASV----NTLLETLSQISLS-GVADI.IASEL----------------
O70510_RAT/13-96ENP.NSLISQ-SFM--LLKK-WVTR...DGKNATT----DALTSVLTKINRI-DIVTL.LEGPI----------------
NFKB2_XENLA/826-901TS......SP-TES--LLRN-YELA......GGNL----KELINTLQSMGLN-EGVEL.LCKSE----------------
TNR21_HUMAN/416-498GYT.A.DHER-AYA--ALQH-WTIR....GPEASL----AQLISALRQHRRN-DVVEK.IRGLM----------------
TNR6_PIG/228-311DNP.KDTAEQ-KVQ--LLRN-WYLY...HGKKDAY----CTLIQGLRKAKLS-ALADK.INDIV----------------
CRADD_MOUSE/117-198NHP.HNVHSQ-VVE--AFVR-WRQR...FGKQATF----LSLHKGLQAVEAD-PSL...LQHML----------------
O96407_LITSI/145-224QFV.G...LE-AIT--ILRI-WRFL...KKEQATP----AALRSAFQRIGRD-DVVRE.MNRAE----------------
O96458_STRPU/1012-1088VP......SP-TAV--ILKQ-FEAM......DGTI----KELRDVLSSMNHI-EAVAL.LDQAV----------------
ANK1_HUMAN/1404-1487ENP.NSLLEQ-SVA--LLNL-WVIR...EGQNANM----ENLYTALQSIDRG-EIVNM.LEGSG----------------
TNR16_CHICK/334-410EE......SP-ARA--LLAD-WSAK.....ETATL----DALLVALRKIQRG-DIAES.LYSES----------------
NFKB1_HUMAN/817-892SP......AP-SKT--LMDN-YEVS......GGTV----RELVEALRQMGYT-EAIEV.IQAAS----------------
TNR1A_RAT/364-448QNG.RCLREA-HYS--MLEA-WRRR..TPRHEATL----DVVGRVLCDMNLR-GCLEN.IRETL----------------
THOC1_RAT/249-331.YS.EDMKKR-AKQ--LLVA-WKDQ...EGVHETT----DNLIGALNKSGLS-DLAES.LTNDT----------------
NFKB2_CHICK/783-857TP......SP-A.S--ALRS-YELP......GGSL----GGLLEALDSMGLR-GAVRM.LRKPE----------------
NFKB2_HUMAN/776-851TT......SP-SGS--LLRS-YELA......GGDL----AGLLEALSDMGLE-EGVRL.LRGPE----------------
KPEL_DROME/43-121QRG.R...SA-SNE--FLNI-WGGQ.....YNHTV----QTLFALFKKLKLH-NAMRL.IKDYV----------------
FADD_HUMAN/98-181RYP.RNLTER-VRE--SLRI-WKNT...EKENATV----AHLVGALRSCQMN-LVADL.VQEVQ----------------
RIPK1_HUMAN/584-669ERD.G.LKEK-VYQ--MLQK-WVMR..EGIKGATV----GKLAQALHQCSRI-DLLSS.LIYVS----------------
Q24241_DROME/1442-1526EFLLNDSVKQ-SMA--MLQL-WLEH....GGILTG----NVLAEALYKIGRS-DIVEKSFKNAE----------------
UNC5_CAEEL/828-910DC......SP-TSL--LLDL-WEAS..SSGSARAV----PDLLQTLRVMGRP-DAVMV.LERFL----------------
MYD88_DANRE/23-101RD......CP-FEK--VLTD-WETR.....PDATV----ANLLSILEKAERK-DVISE.LKEIL----------------
Q61304_MOUSE/1001-1084ENP.NSLLDQ-STA--LLTL-WVDR...EGENAKT----SPQKPALYRSWTL-PTASY.ILDQD----------------
TNR6_RAT/220-303NSP.QDAAEQ-KIQ--LLQC-WYQS...HGKTGAC----QALIQGLRKANRC-DIAEE.IQAMV----------------
Q6DIU6_XENTR/20-97SR......SR-TEE--VVWA-WSNR......NAVV----GELLSILRSLNLL-RALDV.FESWR----------------
Q6DJ38_XENTR/115-196QNR.YNLQSQ-IVE--GFVK-WKQR...MGSKATM----LQLWQALQAAEAD-..LSV.MQQIL----------------
Q6DJ81_XENTR/230-311NNR.DNAREQ-NIA--MLRA-WYQQ.....NPGDV----NDLLASLHDINLH-TPART.IASIL----------------
Q6E5U7_ICTPU/222-303ENP.HDASER-AYH--LLKA-WYEK...HGKTGAY----RTLRENLIAIGKR-SKADE.VRELI----------------
Q6GLZ4_XENLA/237-318NNR.GNSREQ-KIA--MLQA-WYQQ.....NSGDV----NDLLATLHAIHLH-TPART.IVRIL----------------
Q6JA22_XENLA/305-382GE......DP-VHT--LLTD-WSSK.....ESSTL----EVLCAALVNMERA-DVVEN.LNSAN----------------
Q6K198_DANRE/796-869SA......SP-CQK--LLES-YQLS......GGPV----DGLVEALQALGVR-EGVRL.LRDSQ----------------
Q6NRK5_XENLA/1308-1393VQR.DFLPSP-ICA--LLQD-LNNS.....PESTI----SLLMYKLRELGRR-DAADF.LLKAS----------------
Q6Q782_ICTPU/100-183KHP.RNLEEQ-VRE--WFKE-WMKM...HKAEAKV----DELIRALRDCTLN-YTADV.VQMNL----------------
UN5CL_MOUSE/414-491QR......SP-AAA--ILEL-FEEQ......NGSL----QELHYLMTSMERL-DCASA.IQNYL----------------
Q76B98_XENLA/237-318NNR.DNSREQ-KIA--MLQA-WHQQ.....KSGDV----NKLLSYLHSIQLH-TPART.IVQKL----------------
Q7KU92_DROME/1420-1501QNT.DSIARQ-AQS--MIRL-YKDK.....PNYDI----LSLETALKNIGRD-DIMKK.CKSGR----------------
Q7PT80_ANOGA/1055-1127AP......SP-ARM--LLGY-FEMQ......QLHL----DRLIDMLRVLELR-DPIRS.IDEMI----------------
Q7SYB2_DANRE/574-655EDV.D...LQ-AKM--LLVA-WQDR...EGSQATM----ESLVTALNAAGFN-NIADN.L.SET----------------
Q7T3M8_CHICK/322-403NWP.NDIDEQ-SYQ--MLLM-WKNK...MGEKQSI----IKLLDELWDIDTR-.AYSN.IVHTL----------------
Q7ZXL7_XENLA/573-655EDA.K...MR-AKL--LLLG-WQER...EGGQANI----EILISALNSAGLN-ELAEN.LTNDS----------------
Q7ZYE4_XENLA/22-101RTG.V...SV-TGE--LMWS-WGQK......LPTL----QELVDRLQKLELY-RALGI.LQQWA----------------
Q7ZZX8_CHICK/576-661ERD.G.LKEK-VHQ--MLHK-WIMG..QGSKGATV----GKIAKALFGCRKL-DLLTS.LMQMS----------------
Q800K8_PAROL/304-384YE......DK-IHD--LLNI-WLEQ...EGREASL----NKLLKALLDLNQR-RTAET.VKEKA----------------
DAPK1_MOUSE/1311-1396ASR.DFLPSP-VHA--LLQE-WTSY.....PESTV----GILISKLRELGRR-DAADF.LLKAS----------------
Q861W6_FELCA/225-308DNL.QDTAEQ-KVQ--LLRN-WYQL...HGRKGAY----YALVKGLRKANLC-ALAEK.IEDMV----------------
Q8BR10_MOUSE/28-103SE......QR-TAS--VLWP-WINR......NARV----ADLVHILTHLQLL-RARDI.ITAWH----------------
Q8BY25_MOUSE/116-192RPQ.....SP-TLE--FLFR-NSQR........TV----GQLMEALPAVPQG-RCGED.PAQVG----------------
Q8BYY1_MOUSE/338-411EA......CP-VRA--LLAS-WGAQ.....DSATL----DALLAALRRIQRA-DIVES.LCSES----------------
Q8C1X0_MOUSE/31-109RP......DP-TRS--LLDA-WQGR.....SGASV----GRLLELLALLDRE-DILKE.LKSRI----------------
ANK2_MOUSE/3523-3606ENP.NSLQDQ-SHA--LLKY-WLER...DGKHATD----TILIECLTKINRM-DIVHL.LETNT----------------
Q8CD57_MOUSE/98-181KYP.RSLSER-VRE--SLKV-WKNA...EKKNASV----AGLVKALRTCRLN-LVADL.VEEAQ----------------
NRADD_MOUSE/143-222DQ......MP-AYT--LLRN-WAAQ...EGNRATL----RVLEDALAAIGRE-DVVQV.LSSPA----------------
Q8IUB6_HUMAN/5-88DNV.QDTAEQ-KVQ--LLRN-WHQL...HGKKEAY----DTLIKDLKKANLC-TLAEK.IQTII----------------
UNC5D_MOUSE/862-939QS......SP-SAV--ILNL-WEAR...HQQDGDL----DSLACALEEIGRT-HT..K.LSNIT----------------
IRAK3_MOUSE/26-106NQG.K...SG-TRE--LLWS-WAQK......NKTI----GDLLEVLQDMGHQ-RAIHL.IINYG----------------
Q8MQG0_CAEEL/1498-1578NYP.G...QE-CKN--TLKI-WIHL...KKEDANQ----DNLDQALRQIGRD-DIVRS.IAYGE----------------
Q8MV43_AEDAE/578-650SV......NP-AGM--LLNY-FEMQ......KVKL----EHLIDVLQALDQK-EAIHY.IDEMI----------------
Q8VD70_MOUSE/303-383CR....FRDQ-QYE--MLKR-WRQQ.....QPAGL----GAIYAALERMGLE-GCAED.LRSRL----------------
EDAD_MOUSE/116-192RPQ.....SP-TLE--FLFR-NSQR........TV----GQLMELCRLYHRA-DVEKI.LRRWV----------------
EDAR_ORYLA/403-476........SD-GLQ--LFER-VSTA......GYSI----PDLLARLVQIERL-DAVES.LCADV----------------
MYD88_HUMAN/31-109QA......DP-TGR--LLDA-WQGR.....PGASV----GRLLELLTKLGRD-DVLLE.LGPSI----------------
Q9BDP0_AOTTR/226-309DNI.KDTAEQ-KVQ--LLRN-WYQL...HGKKDAY----DTLINGLKKANLT-ALVEK.IQNII----------------
Q9DF34_DANRE/266-346LFP.E...DR-VYE--LLKI-WMEK...EGLKADF----NSLIDALIYLDQR-LSAEN.IIAKA----------------
MY88A_XENLA/26-105YP......DS-TMK--LLED-WEKK....CFRATV----GGLLEMLKKMERN-DILTD.LGPLI----------------
Q9DFV0_DANRE/349-429QQP.M...DK-VYD--LLRV-WMQK...EGLRANI----NTLLQALLDLDQR-YSAEH.IASKA----------------
Q9DGH7_CHICK/153-236DNS.NNTSEQ-KIK--LFQK-WYQK...HGMGGAY----ETLICSLRDLKMR-TAADK.IERKL----------------
AND1A_MACFA/379-467TGT.RSYQEH-GHR--MLLI-WLHGVSTAGENPS.----KALFEGLVTIGRR-DLAEL.AVASV----------------
Q9IAR7_CHICK/275-357HDR.V.SCEP-FYQ--MLNT-WLNQ...QGSKASV----NTLLETLPRIGLS-GVADI.IASEL----------------
Q9N9X2_GEOCY/23-103DQP.....DK-RRR--LVNL-WAQT...NGSQATY----YALVEALLKAHMR-ADAEK.VCNLL----------------
Q9NHG0_DROME/203-289QMH.GNIREV-IYQ--LLLQ-WIRS..SADGVATV----GRLTTLLWESQHR-ELRAA.HETGL----------------
Q9PRG7_XENLA/319-395EE......FP-VRA--MLSD-WSSK.....DSATT----DALYTALRKIQRD-DIAQS.LNSDS----------------
BG4_DROME/152-237RYP.HDLKSQ-ILR--LLQL-IEEDD.CHDPKHFL----LRLCRALGDCGRN-DLRKR.VEQIM----------------
Q9VNI8_DROME/607-687EHP.T.ANVA-CVK--MLTN-WISD....DDDATL----ENWAYMLEGLEMN-KAAEA.VKAII----------------

PF00619

CASP4_MOUSE/3-90NAE...RSDK.RWV..FVDA.MKKK-----HSKVG----EMLLQTFFS..VD-PGSHH-GEANL----------------
BIRC3_MOUSE/441-524KPH...TL.Q.AST..LIDT.VLAK-----GNTAA----TSFRNSLRE..ID-PALYR-DIFVQ----------------
VCLAP_EHV2/26-110RAT...SRSR.AGL..LVDM.CQ.D-----HPRGF----QCLKESCKNEVGQ-EHLVD-LLERA----------------
CASP5_HUMAN/61-147DTK...IEDK.ALI..LVDS.LR.K-----NRVAH----QMFTQTLLN..MD-QKITS-VKPLL----------------
CAR14_HUMAN/20-106LTN...SAMR.AGH..LLDL.LKTR-----GKNGA----IAFLESLKF..HN-PDVYT-LVTGL----------------
CAR11_MOUSE/23-109LPS...KINR.AGR..LLDI.LHTK-----GQRGY----VVFLESLEF..YY-PELYK-LVTGK----------------
IFIH1_HUMAN/115-200NNG...NESG.VRE..LLKR.IV.Q-----KENWF----SAFLNVLRQ.TGN-NELVQ-ELTGS----------------
Q80UH6_MUSMC/8-94GQP...LSHS.ARR..LLDT.VWNK-----GVWGC----QKLLEAMQE..AQ-ANSHT-FELHG----------------
Q7ZXD2_XENLA/10-94YRS...DYAQ.NVA..LLNL.LPKR-----GPRAF----SAFCNALHS.TNQ-EHLAQ-QVEKE----------------
NALP1_HUMAN/1379-1462ENT...RPSQ.MRK..LFSL.SQSW-----DRKCK----DGLYQALKE..TH-PHLIM-ELWEK----------------
CAR14_MOUSE/20-106SRF...TNSA.MRVGHLLDL.LKAR-----GKNGA----IAFLESLKF..HN-PDVYT-LVTGL----------------
APAF_DANRE/6-90KAT...RKEQ.AVA..LLET.LLRK-----DNRAY----ISFYNALIR.ESY-GDLAS-LLHSD----------------
APAF_HUMAN/6-90EPT...QQQR.AAM..LIKM.ILKK-----DNDSY----VSFYNALLH.EGY-KDLAA-LLHDG----------------
Q9Y1U6_PRIPA/7-91......MSNG.RLD..LMRS.LTKQ-----GSIAF----DEFFLSLVH.SQQ-VHLAD-SLRPL----------------
CASP2_RAT/37-121KGG...SFSQ.NVE..LLNL.LPKR-----GPQAF----DAFCEALRE.TRQ-GHLED-LLLTT----------------
Q6YH84_9VIRU/6-93NDT...RADI.ARA..LIDS.VTKQ-----GDVAC----SLFAGAIAR..QD-VVLAD-AMGIS----------------
CASP1_HUMAN/3-90NAT...VMDK.TRA..LIDS.VIPK-----GAQAC----QICITYICE..ED-SYLAG-TLGLS----------------
Q80UH2_MUSSP/104-191IFT...SSQR.ARR..LLDL.AAVK-----ANGLA----AFLLQHVRE.LPA-PLPLP-YEAAE----------------
Q8JFQ3_CYPCA/17-103DPSLVIRRRK.VGM..LLDI.LQRT-----GLKGY----EAFLESLEL..DY-PDVYR-KITGK----------------
ASC_HUMAN/112-195EPT...NPSK.MRK..LFSF.TPAW-----NWTCK----DLLLQALRE..SQ-SYLVE-DLERS----------------
CASP1_CANFA/3-90HST...VMDQ.ARV..LIDS.VLRK-----GPNAC----QIFISNICN..ED-IHLAQ-TLGLS----------------
CRADD_MOUSE/6-89QTT...GLRK.TML..LLDI.LPSR-----GPKAF----DTFLDSLQE...F-PWVRE-KLEKA----------------
Q6ZM93_DANRE/494-578CTS...VKQQ.TGQ..LIDL.VLSK-----GNAAA----EVFRNWIKK..ND-VYLLR-ELMAQ----------------
RIPK2_HUMAN/437-524KPT...RTSK.VRQ..LLDT.TDIQ-----GEEFA----KVIVQKLKD.NKQ-MGLQP-YPEIL----------------
BIRC2_HUMAN/458-542KTQ...IPLQ.ARE..LIDT.ILVK-----GNAAA----NIFKNCLKE..ID-STLYK-NLFVD----------------
CASP1_PIG/3-90NAT...VMDK.ARA..LIDS.VIRK-----GPQAC----QICINHICG..DD-PHLAG-VLELS----------------
CED3_CAERE/7-91CRT...ERDK.RKE..QVKA.VQRR-----GDEAF----DRFYDALRD.TGH-ELLAA-VLEPL----------------
Q8C3Q9_MOUSE/6-92SGS...RRDQ.ARQ..LVTD.LETR-----GRQAL----PLFISCLED.TGQ-GTLAS-LLQSG----------------
NOL3_HUMAN/9-96LPD...AERR.VRR..LLLL.VQGK-----GEAAC----QELLRCAQRTAGA-PDPAW-DWQHA----------------
CASPD_BOVIN/3-90DAK...LQDK.ARV..LVDS.IRQK-----NQEAG----QVFVQTFLN..ID-KNSTS-IKAPE----------------
ASC_BOVIN/112-195ERT...SSDK.MRK..LFSF.SPAW-----NMTCK----DLLLQALRD..TQ-PYLVD-DLEQS----------------
NOD1_MOUSE/20-105CPT...KPDK.VRK..ILDL.VQSK-----GEEVS----EFFLYVLQQ.LED-AYVDL-RLWLS----------------
CASP1_FELCA/3-90NAT...VMDK.ARA..LIDS.VLRK-----GPRAC----QIFICHICE..ED-THLAE-TLGLS----------------
BIR_CHICK/451-535TTQ...TPSQ.ARE..LIDT.VLVK-----GNAAA----SIFRNCLKD..FD-PVLYK-DLFVE----------------
BCL10_HUMAN/18-102RTS...SRKR.AGK..LLDY.LQ.E-----NPKGL----DTLVESIRREKTQ-NFLIQ-KITDE----------------
CED3_CAEEL/7-91CGT...VREK.RRE..IVKA.VQRR-----GDVAF----DAFYDALRS.TGH-EGLAE-VLEPL----------------
Q8JHU4_DANRE/470-557QTT...RTAK.VRK..LLDT.CERH-----SEEFC----RVVVRKLQD.NKQ-MGLQP-YPDLS----------------
Q8I6Y2_GEOCY/9-92ART...DGEA.ADE..LMKA.LRRR-----DSSVL----DILVECLAE..QQ-EANAD-LIKKI----------------
CASPC_MOUSE/4-91ASF...ILNK.AEN..LVEN.FLEK-----TDMAG----KIFAGHIAN..SQ-EQLSL-QFSND----------------
NLRC4_HUMAN/1-87EKV...EQDA.ARG..IIHM.ILKK-----GSESC----NLFLKSLKE..WN-YPLFQ-DLNGQ----------------
Q8K4I9_MERUN/3-90NAT...VKDK.ARH..LCDS.VTQK-----GPEAS----QILITYICK..EA-CFVAK-KMELE----------------
CASP2_CHICK/12-96KSG...SFSQ.NVE..FLNL.LPKR-----GPNAF----SAFCEALQE.TKQ-QHLAE-MILKT----------------
ASC_DANRE/117-202KET...PQKK.MRE..LLTGPITCA-----GNKGK----EVLYDALRE..SN-KFLMD-DLEDA----------------
CAR10_MOUSE/28-114YRFP.CRANR.TGR..LIDI.LRCR-----GKRGF----EAFLEALEF..YY-PEHFT-LLTGQ----------------
NOD2_HUMAN/31-121LGQ...PLSHLARR..LLDT.VWNK-----GTWAC----QKLIAAAQE..AQ-ADSQS-PKLHG----------------
CARD8_HUMAN/345-429EKT...RQSK.NEA..LLSM.VEKK-----GDLAL----DVLFRSISE..RD-PYLVS-YLRQQ----------------
Q6XZE5_HUMAN/8-93VTD...LLKK.SRK..LLIL.VQKK-----GEATC----QHFLKCLFS..TF-PQSAA-ICGLR----------------
O95601_HUMAN/3-90DAK...TEDK.VRV..MADS.MQEK-----QRMAG----QMLLQTFFN..ID-QISPN-KKGDK----------------
Q8CHK8_RAT/110-193ETP...NQNK.MRK..LFSF.APAW-----NLTCK----NLFLEALRQ..TQ-PYLVT-DLEQS----------------
ASC_MOUSE/110-193ETT...SQDK.MRK..LFSF.VPSW-----NLTCK----DSLLQALKE..IH-PYLVM-DLEQS----------------
CAR18_HUMAN/3-90NDT...VMDK.ARV..LIDL.VTGK-----GPKSC----CKFIKHLCE..ED-PQLAS-KMGLH----------------
PIAP_PIG/198-282KTQ...TSLQ.ARE..LIDI.ILVK-----GNYAA----TIFKNSLQE..ID-PMLYK-HLFVQ----------------
CASP1_MOUSE/3-90NIT...AMDK.ARD..LCDH.VSKK-----GPQAS----QIFITYICN..ED-CYLAG-ILELQ----------------
IFIH1_MOUSE/115-200NSG...NESG.VRE..LLRR.IV.Q-----KENWF----STFLDVLRQ.TGN-DALFQ-ELTGG----------------
CED4_CAEEL/7-90MST...RLER.IAN..FLRI.YRRQ-----ASELG----PLIDFFNYN..NQ-SHLAD-FLEDY----------------
CAS1A_XENLA/2-89NNT...NRDR.CRA..MIDS.VKKK-----GDDPS----NILLESLVK..NH-KTLAK-SLGLH----------------
CASPC_HUMAN/4-91LKF...VVSN.AEN..LVDD.ITET-----AQIAG----KIFREHLWN..SK-KQLSS-DISSD----------------
Q9IB63_XENLA/6-90EGT...RRDQ.ARK..LLVE.LETR-----GSQAF----PLFLLCLKE.TAQ-HDLAD-FLQSD----------------
Q80VR5_MOUSE/6-90QAT...QYQR.AAA..LIKM.ILNK-----DNCAY----ISFYNALLH.EGY-KDLAA-LLQSG----------------
CASP9_HUMAN/6-92SGS...RRDQ.ARQ..LIID.LETR-----GSQAL----PLFISCLED.TGQ-DMLAS-FLRTN----------------

PF02758

NAL4E_MOUSE/6-89----
MEFV_MOUSE/5-88----
NALP6_HUMAN/18-99----
NAL11_HUMAN/7-87----
NALP5_HUMAN/61-144----
IFI4_MOUSE/6-84----
PYDC3_MOUSE/10-88----
IFI5A_MOUSE/6-84----
NAL13_HUMAN/13-103----
NALP9_BOVIN/7-90----
NALP4_HUMAN/7-90----
PYDC1_HUMAN/4-87----
Q5RGK3_DANRE/4-82----
Q5RGA0_DANRE/4-82----
NALP8_HUMAN/37-119----
MEFV_RAT/5-88----
AIM2_HUMAN/6-83----
Q4SV51_TETNG/5-87----
MEFV_HUMAN/5-88----
Q4VBV3_DANRE/5-86----
NALP9_HUMAN/7-90----
IFIXL_MOUSE/6-83----
Q8V3S3_SWPV1/3-81----
Q9I9L7_DANRE/5-85----
NAL12_HUMAN/9-91----
NALP7_HUMAN/6-89----
NAL14_HUMAN/11-93----
Q66JP4_MOUSE/6-89----
Q4U0E2_DANRE/4-85----
Q5F3J4_CHICK/5-88----
IF16_HUMAN/6-84----
MNDA_HUMAN/6-84----
ASC_HUMAN/4-87----
Q6DJG0_XENLA/5-88----
Q5U2R8_RAT/6-84----
Q5SXI6_MOUSE/4-87----
Q6UQE6_MOUSE/9-91----
IFI3_MOUSE/5-83----

PF01335

Q9JHX4_RAT/3-86----
Q9I8J3_DANRE/99-179----
CFLA_EHV2/2-75----
CFLA_MCV1/9-84----
FADD_HUMAN/4-87----
P88961_HHV8/94-170----
DEDD2_HUMAN/25-110----
Q90WU1_CHICK/3-86----
CFLAR_HUMAN/2-79----
VG71_SHV21/3-81----
CASP8_MOUSE/3-86----
CFLAR_MOUSE/7-84----
Q8CD57_MOUSE/4-87----
Q99CX0_BHV4/95-177----
CASP8_HUMAN/101-183----
CFLA_EHV2/93-170----
CFLA_MCV1/96-181----
O11300_MCV1/10-82----
Q9IB62_XENLA/98-177----
PEA15_HUMAN/4-87----
Q9IB62_XENLA/3-86----
Q9JHX4_RAT/101-183----
Q9J2H2_9GAMA/94-168----
Q90WU1_CHICK/101-183----
Q9IB64_XENLA/113-193----
DEDD_HUMAN/25-109----
O11300_MCV1/94-170----
CASP8_HUMAN/3-86----
VG71_SHV21/94-167----
CFLAR_HUMAN/93-176----
Q8UVG5_DANRE/102-185----
CFLAR_MOUSE/98-184----
Q8UVG5_DANRE/5-89----
CASPA_HUMAN/20-102----
CASP8_MOUSE/101-183----
Q9IB64_XENLA/17-100----
CASPA_HUMAN/115-193----

PF14786

E8NH30_DROME/27-172ISLE
TUBE_DROVI/27-173ISLD
B0X4E9_CULQU/4-135IDIE
Q171H8_AEDAE/4-133IDVD

PF00531

NFKB1_CHICK/816-891----
TNR6_MOUSE/223-306----
Q7QD54_ANOGA/47-126----
Q7QH59_ANOGA/617-697----
TR10B_MOUSE/273-356----
TR10A_HUMAN/366-448----
TR10B_HUMAN/340-422----
DTHD1_HUMAN/679-764----
TR11B_MOUSE/293-365----
UNC5A_RAT/817-896----
UNC5B_RAT/864-943----
TR11B_RAT/279-365----
UNC5C_MOUSE/850-929----
TNR1A_BOVIN/373-457----
IRAK2_HUMAN/14-94----
DAPK_CAEEL/1307-1389----
O57408_MELGA/275-357----
O70510_RAT/13-96----
NFKB2_XENLA/826-901----
TNR21_HUMAN/416-498----
TNR6_PIG/228-311----
CRADD_MOUSE/117-198----
O96407_LITSI/145-224----
O96458_STRPU/1012-1088----
ANK1_HUMAN/1404-1487----
TNR16_CHICK/334-410----
NFKB1_HUMAN/817-892----
TNR1A_RAT/364-448----
THOC1_RAT/249-331----
NFKB2_CHICK/783-857----
NFKB2_HUMAN/776-851----
KPEL_DROME/43-121----
FADD_HUMAN/98-181----
RIPK1_HUMAN/584-669----
Q24241_DROME/1442-1526----
UNC5_CAEEL/828-910----
MYD88_DANRE/23-101----
Q61304_MOUSE/1001-1084----
TNR6_RAT/220-303----
Q6DIU6_XENTR/20-97----
Q6DJ38_XENTR/115-196----
Q6DJ81_XENTR/230-311----
Q6E5U7_ICTPU/222-303----
Q6GLZ4_XENLA/237-318----
Q6JA22_XENLA/305-382----
Q6K198_DANRE/796-869----
Q6NRK5_XENLA/1308-1393----
Q6Q782_ICTPU/100-183----
UN5CL_MOUSE/414-491----
Q76B98_XENLA/237-318----
Q7KU92_DROME/1420-1501----
Q7PT80_ANOGA/1055-1127----
Q7SYB2_DANRE/574-655----
Q7T3M8_CHICK/322-403----
Q7ZXL7_XENLA/573-655----
Q7ZYE4_XENLA/22-101----
Q7ZZX8_CHICK/576-661----
Q800K8_PAROL/304-384----
DAPK1_MOUSE/1311-1396----
Q861W6_FELCA/225-308----
Q8BR10_MOUSE/28-103----
Q8BY25_MOUSE/116-192----
Q8BYY1_MOUSE/338-411----
Q8C1X0_MOUSE/31-109----
ANK2_MOUSE/3523-3606----
Q8CD57_MOUSE/98-181----
NRADD_MOUSE/143-222----
Q8IUB6_HUMAN/5-88----
UNC5D_MOUSE/862-939----
IRAK3_MOUSE/26-106----
Q8MQG0_CAEEL/1498-1578----
Q8MV43_AEDAE/578-650----
Q8VD70_MOUSE/303-383----
EDAD_MOUSE/116-192----
EDAR_ORYLA/403-476----
MYD88_HUMAN/31-109----
Q9BDP0_AOTTR/226-309----
Q9DF34_DANRE/266-346----
MY88A_XENLA/26-105----
Q9DFV0_DANRE/349-429----
Q9DGH7_CHICK/153-236----
AND1A_MACFA/379-467----
Q9IAR7_CHICK/275-357----
Q9N9X2_GEOCY/23-103----
Q9NHG0_DROME/203-289----
Q9PRG7_XENLA/319-395----
BG4_DROME/152-237----
Q9VNI8_DROME/607-687----

PF00619

CASP4_MOUSE/3-90----
BIRC3_MOUSE/441-524----
VCLAP_EHV2/26-110----
CASP5_HUMAN/61-147----
CAR14_HUMAN/20-106----
CAR11_MOUSE/23-109----
IFIH1_HUMAN/115-200----
Q80UH6_MUSMC/8-94----
Q7ZXD2_XENLA/10-94----
NALP1_HUMAN/1379-1462----
CAR14_MOUSE/20-106----
APAF_DANRE/6-90----
APAF_HUMAN/6-90----
Q9Y1U6_PRIPA/7-91----
CASP2_RAT/37-121----
Q6YH84_9VIRU/6-93----
CASP1_HUMAN/3-90----
Q80UH2_MUSSP/104-191----
Q8JFQ3_CYPCA/17-103----
ASC_HUMAN/112-195----
CASP1_CANFA/3-90----
CRADD_MOUSE/6-89----
Q6ZM93_DANRE/494-578----
RIPK2_HUMAN/437-524----
BIRC2_HUMAN/458-542----
CASP1_PIG/3-90----
CED3_CAERE/7-91----
Q8C3Q9_MOUSE/6-92----
NOL3_HUMAN/9-96----
CASPD_BOVIN/3-90----
ASC_BOVIN/112-195----
NOD1_MOUSE/20-105----
CASP1_FELCA/3-90----
BIR_CHICK/451-535----
BCL10_HUMAN/18-102----
CED3_CAEEL/7-91----
Q8JHU4_DANRE/470-557----
Q8I6Y2_GEOCY/9-92----
CASPC_MOUSE/4-91----
NLRC4_HUMAN/1-87----
Q8K4I9_MERUN/3-90----
CASP2_CHICK/12-96----
ASC_DANRE/117-202----
CAR10_MOUSE/28-114----
NOD2_HUMAN/31-121----
CARD8_HUMAN/345-429----
Q6XZE5_HUMAN/8-93----
O95601_HUMAN/3-90----
Q8CHK8_RAT/110-193----
ASC_MOUSE/110-193----
CAR18_HUMAN/3-90----
PIAP_PIG/198-282----
CASP1_MOUSE/3-90----
IFIH1_MOUSE/115-200----
CED4_CAEEL/7-90----
CAS1A_XENLA/2-89----
CASPC_HUMAN/4-91----
Q9IB63_XENLA/6-90----
Q80VR5_MOUSE/6-90----
CASP9_HUMAN/6-92----

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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