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497  structures 5019  species 13  interactions 35666  sequences 221  architectures

Clan: Flavoprotein (CL0042)

Summary

Flavoprotein Add an annotation

Members of this clan are FMN or FAD-binding redox proteins. Flavoproteins act in various electron-transport systems as functional analogues of ferredoxin. They are characterised by an open twisted alpha/beta structure consisting of five parallel beta-sheets connected by alpha-helices which surround the sheet.

This clan contains 7 families and the total number of domains in the clan is 35666. The clan was built by RD Finn.

Members

This clan contains the following 7 member families:

Flavodoxin_1 Flavodoxin_2 Flavodoxin_3 Flavodoxin_4 Flavodoxin_5 Flavodoxin_NdrI FMN_red

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
FMN_red (PF03358) 11795 (33.1%) View
Flavodoxin_1 (PF00258) 10556 (29.6%) View
Flavodoxin_2 (PF02525) 7847 (22.0%) View
Flavodoxin_NdrI (PF07972) 2192 (6.1%) View
Flavodoxin_5 (PF12724) 1747 (4.9%) View
Flavodoxin_4 (PF12682) 1133 (3.2%) View
Flavodoxin_3 (PF12641) 396 (1.1%) View
Total: 7 Total: 35666 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 13 interactions for this clan. More...

Interacting families
A B
Flavodoxin_1 p450
NAD_binding_1
Flavodoxin_1
FAD_binding_1
Lactamase_B
Flavodoxin_2
FMN_red
FMN_red Flavodoxin_1
Flavodoxin_2
FMN_red
Flavodoxin_2 Flavodoxin_1
Flavodoxin_2
FMN_red

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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