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264  structures 4170  species 7  interactions 11982  sequences 47  architectures

Clan: GlnB-like (CL0089)

Summary

GlnB-like superfamily Add an annotation

The members of this clan are characterised by the fact the domains, each comprised of four beta-strand and two alpha helices, tend to form tetrameric structures [1].

This clan contains 9 families and the total number of domains in the clan is 11982. The clan was built by RD Finn.

Literature references

  1. Cho Y, Sharma V, Sacchettini JC; , J Biol Chem 2003;278:8333-8339.: Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis. PUBMED:12511575 EPMC:12511575

Members

This clan contains the following 9 member families:

CutA1 DUF190 DUF2007 DUF3240 DUF3582 DUF970 HisG_C Nit_Regul_Hom P-II

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
P-II (PF00543) 4823 (40.3%) View
HisG_C (PF08029) 1973 (16.5%) View
CutA1 (PF03091) 1667 (13.9%) View
DUF2007 (PF09413) 1038 (8.7%) View
DUF970 (PF06153) 826 (6.9%) View
DUF3582 (PF12122) 749 (6.3%) View
DUF190 (PF02641) 725 (6.1%) View
DUF3240 (PF11582) 148 (1.2%) View
Nit_Regul_Hom (PF10126) 33 (0.3%) View
Total: 9 Total: 11982 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 7 interactions for this clan. More...

Interacting families
A B
P-II P-II
AA_kinase
Ammonium_transp
DUF190 DUF190
CutA1 CutA1
HisG_C HisG
HisG_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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