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34  structures 22  species 2  interactions 52  sequences 2  architectures

Clan: Pept_Inhib_IE (CL0096)

Summary

Peptidase Inhibitor Clan IE Add an annotation

The members of this clan are all cystine rich domains, which form a knottin scaffold. This clan should also contain alpha-amylase but currently this family is a singleton and can not be put into Pfam. Also see [1].

This clan contains 2 families and the total number of domains in the clan is 52. The clan was built by RD Finn.

Literature references

  1. Gelly JC, Gracy J, Kaas Q, Le-Nguyen D, Heitz A, Chiche L; , Nucleic Acids Res 2004;32:D156-D159.: The KNOTTIN website and database: a new information system dedicated to the knottin scaffold. PUBMED:14681383 EPMC:14681383

Members

This clan contains the following 2 member families:

CarbpepA_inh Squash

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Squash (PF00299) 37 (71.2%) View
CarbpepA_inh (PF02977) 15 (28.8%) View
Total: 2 Total: 52 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 2 interactions for this clan. More...

Interacting families
A B
Squash Trypsin
Squash

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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