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289  structures 4585  species 2  interactions 15156  sequences 56  architectures

Clan: Phospoesterase (CL0171)

Summary

inositol polyphosphate 1 phosphatase like superfamily Add an annotation

Members of this clan show metal-dependent / lithium sensitive phosphomonoesterase activity. The clan includes inositol polyphosphate 1 phosphatase and fructose 1,6-bisphosphatase [1].

This clan contains 3 families and the total number of domains in the clan is 15156. The clan was built by A Bateman.

Literature references

  1. York JD, Ponder JW, Majerus PW; , Proc Natl Acad Sci U S A 1995;92:5149-5153.: Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. PUBMED:7761465 EPMC:7761465

Members

This clan contains the following 3 member families:

FBPase FBPase_glpX Inositol_P

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Inositol_P (PF00459) 10135 (66.9%) View
FBPase (PF00316) 2715 (17.9%) View
FBPase_glpX (PF03320) 2306 (15.2%) View
Total: 3 Total: 15156 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 2 interactions for this clan. More...

Interacting families
A B
Inositol_P Inositol_P
FBPase FBPase

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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