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20  structures 4464  species 2  interactions 9322  sequences 54  architectures

Clan: Trigger_C (CL0262)

Summary

Trigger factor/SurA domain Add an annotation

This helical domain is found in two families of chaperones. It is found at the N terminus of the SurA proteins and at the C-terminus of the trigger factors where presumably it shares a common but as yet unknown function.

This clan contains 4 families and the total number of domains in the clan is 9322. The clan was built by A Bateman.

Literature references

  1. Ferbitz L, Maier T, Patzelt H, Bukau B, Deuerling E, Ban N; , Nature. 2004;431:590-596.: Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins. PUBMED:15334087 EPMC:15334087

Members

This clan contains the following 4 member families:

SurA_N SurA_N_2 SurA_N_3 Trigger_C

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Trigger_C (PF05698) 4501 (48.3%) View
SurA_N_3 (PF13624) 2783 (29.9%) View
SurA_N (PF09312) 1802 (19.3%) View
SurA_N_2 (PF13623) 236 (2.5%) View
Total: 4 Total: 9322 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 2 interactions for this clan. More...

Interacting families
A B
SurA_N Rotamase
SurA_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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