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26  structures 1437  species 2  interactions 2441  sequences 172  architectures

Clan: TAT (CL0300)

Summary

Twin-Arginine Translocation Motif Add an annotation

This motif is found in a wide range of secreted proteins. It is named after the conserved pair of arginines that is followed by a hydrophobic stretch.

This clan contains 2 families and the total number of domains in the clan is 2441. The clan was built by A Bateman.

Literature references

  1. Berks BC; , Mol Microbiol. 1996;22:393-404.: A common export pathway for proteins binding complex redox cofactors?. PUBMED:8939424 EPMC:8939424
  2. Berks BC, Sargent F, Palmer T; , Mol Microbiol. 2000;35:260-274.: The Tat protein export pathway. PUBMED:10652088 EPMC:10652088

Members

This clan contains the following 2 member families:

TAT_signal UCR_Fe-S_N

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
TAT_signal (PF10518) 1505 (61.7%) View
UCR_Fe-S_N (PF10399) 936 (38.3%) View
Total: 2 Total: 2441 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 2 interactions for this clan. More...

Interacting families
A B
UCR_Fe-S_N Cytochrom_B_N
Cytochrom_C1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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