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75  structures 5254  species 3  interactions 25679  sequences 1413  architectures

Clan: Patatin (CL0323)

Summary

Patatin/FabD/lysophospholipase-like superfamily Add an annotation

This superfamily of enzymes contains a Ser/Asp catalytic dyad. Members of this superfamily are all serine acylhydrolase enzymes.

This clan contains 3 families and the total number of domains in the clan is 25679. The clan was built by A Bateman.

Literature references

  1. Ghosh M, Tucker DE, Burchett SA, Leslie CC; , Prog Lipid Res. 2006;45:487-510.: Properties of the Group IV phospholipase A2 family. PUBMED:16814865 EPMC:16814865

Members

This clan contains the following 3 member families:

Acyl_transf_1 Patatin PLA2_B

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Acyl_transf_1 (PF00698) 13987 (54.5%) View
Patatin (PF01734) 10726 (41.8%) View
PLA2_B (PF01735) 966 (3.8%) View
Total: 3 Total: 25679 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
PLA2_B C2
Acyl_transf_1 Acyl_transf_1
MaoC_dehydratas

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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