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224  structures 4634  species 6  interactions 22171  sequences 139  architectures

Clan: FMN-binding (CL0336)

Summary

FMN-binding split barrel superfamily Add an annotation

This includes those related to the ferredoxin reductase-like FAD-binding domain and those that are Pyridoxine 5'-phosphate oxidase (PNP)-like.

This clan contains 8 families and the total number of domains in the clan is 22171. The clan was built by P Coggill.

Members

This clan contains the following 8 member families:

DUF385 DUF447 Flavin_Reduct FMN_bind_2 Pyrid_oxidase_2 Pyridox_ox_2 Pyridox_oxase_2 Pyridox_oxidase

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Pyridox_oxidase (PF01243) 8674 (39.1%) View
Flavin_Reduct (PF01613) 7912 (35.7%) View
Pyridox_ox_2 (PF12900) 1956 (8.8%) View
DUF385 (PF04075) 1560 (7.0%) View
FMN_bind_2 (PF04299) 884 (4.0%) View
Pyrid_oxidase_2 (PF13883) 676 (3.0%) View
Pyridox_oxase_2 (PF12766) 319 (1.4%) View
DUF447 (PF04289) 190 (0.9%) View
Total: 8 Total: 22171 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 6 interactions for this clan. More...

Interacting families
A B
Pyridox_oxidase Pyridox_oxidase
PNPOx_C
DUF2470
DUF447 DUF447
FMN_bind_2 FMN_bind_2
Flavin_Reduct Flavin_Reduct

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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