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116  structures 6017  species 4  interactions 46990  sequences 209  architectures

Clan: DNA-mend (CL0382)

Summary

DNA breaking-rejoining enzyme superfamily Add an annotation

This is a superfamily of DNA recombinases, topoisomerases and integrases.

This clan contains 7 families and the total number of domains in the clan is 46990. The clan was built by A Bateman.

Members

This clan contains the following 7 member families:

DUF3435 DUF3504 Flp_C Integrase_1 Phage_Integr_2 Phage_integrase Topoisom_I

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Phage_integrase (PF00589) 44346 (94.4%) View
Topoisom_I (PF01028) 1273 (2.7%) View
DUF3435 (PF11917) 446 (0.9%) View
DUF3504 (PF12012) 439 (0.9%) View
Integrase_1 (PF12835) 412 (0.9%) View
Phage_Integr_2 (PF13009) 56 (0.1%) View
Flp_C (PF05202) 18 (0.0%) View
Total: 7 Total: 46990 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 4 interactions for this clan. More...

Interacting families
A B
Flp_C Flp_N
Flp_C
Phage_integrase Phage_integrase
Phage_int_SAM_1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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