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52  structures 3672  species 2  interactions 6801  sequences 66  architectures

Clan: RMMBL_DRMBL (CL0398)

Summary

RNA/DNA-metabolising metallo-beta-lactamase motif Add an annotation

This clan contains the fifth motif found in RNA and DNA metabolising metallo-beta-lactamases. The fifth motif appears to be specific to function [1].

This clan contains 2 families and the total number of domains in the clan is 6801. The clan was built by J Mistry.

Literature references

  1. Callebaut I, Moshous D, Mornon JP, de Villartay JP; , Nucleic Acids Res 2002;30:3592-3601.: Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family. PUBMED:12177301 EPMC:12177301

Members

This clan contains the following 2 member families:

DRMBL RMMBL

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
RMMBL (PF07521) 6209 (91.3%) View
DRMBL (PF07522) 592 (8.7%) View
Total: 2 Total: 6801 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 2 interactions for this clan. More...

Interacting families
A B
RMMBL Lactamase_B
Beta-Casp

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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