Sequence alignment for CL0400

PF10439

Q8DVP7_STRMU/1-72M.N-----TQ...AFEQFNVMDNEALSTVEG.....G.........GMIRCALGTAGSAGLGFVGGMGAGTVTLPV....
A3FKG3_9LACO/1-67M..-----..........KVLNECQLQTVVG.....G......KNWSVAKCGGTIGTNIAIGAWRGARAGSFFGQP....
Q8DSA3_STRMU/1-59M..-----...EKQYNNFKILNTDALENIQG.....G........GRAPRCAALVGASIYDGLAV...............
Q5FI73_LACAC/1-70M..-----.......EKLMVLNEEKLSYVIG.....G......GNPKVAHCASQIGRSTAWGAVSGAATGTAVGQA....
Q73F42_BACC1/1-68M..-----........NLETLTEKELLEISA.....G.........GAGKCVAGIASGAALGFLNGASYTWEFGPAVI..
A1KWV2_STAAU/1-68M..-----..........KKLETKELVSING.....G......KKNTWQQNVSGAIGSTVAGAGLGGAICGP........
Q6XVH3_LACSK/1-59M..-----.......KNVQSLSKEELVLVVG.....G........YTAKQCLQAIGSWGIAGTGAGA.............
O85756_9LIST/1-67M..-----.......HKVKKLNNQELQQIVG.....G........YSSKDCLKDIGKGIGAGTVAGAAGGGLAAG.....
O54454_STRTR/1-72M..-----..NTITICKFDVLDAELLSTVEG.....G........YSGKDCLKDMGGYALAGAGSGALWGAPAGG.....
Q9ETC8_STRPN/1-84M..-----..DTKIMEQFHEMDITMLSSIEG.....G.......KNNWQTNVLEGGGAAFGGWGLGTAICAASGVGAPFM
Q5M2W2_STRT2/1-71M.A-----TQ...TIENFNTLDLETLASVEGGGCSWG...........GFAKQGVATGVGNGLRLGIKTRTW........
Q08GB9_LACAM/1-73M..-----.......SKAEVLNEEELTDVVG.....G...THGHNGKVAKCGGYILRGAGTGALTGALTGTAAGAA....
Q8KWI0_9LACO/1-60M..-----......MKEFTVLTECELAKVDG.....G........KRGPNCVGNFLGGLFAGAAAGVPLG..........
Q8DS95_STRMU/1-75M.N-----TQ...AFEQFNVMDNEALSAVEG.....G........GRGWNCAAGIALGAGQGYMATAGGTAFLGPYAI..
Q03D40_LACC3/1-67M..-----.......SKTRKLSELELQQFVG.....G........SDSNKCLMGLVGGWAIGGLNGAGSLSGFGP.....
O54455_STRTR/1-64M..-----....KQYNGFEVLHELDLANVTG.....G...........QINWGSVVGHCIGGAIIGGAFSGG........
LAFX_LACJO/1-59M..-----...........KLNDKELSKIVG.....G........NRWGDTVLSAASGAGTGIKACKSFGP.........
A5MPT6_STRPN/1-63M..-----.......NTYCNINETMLSEVYG.....G........NSGGAAVVAALGCAAGGVKYGKILGP.........
Q9A139_STRP1/1-69M..-----......IKFAEEIQKEELFHIIG.....G........YSATDCKNHLIGGITSGAIAGGVGAGMATLG....
Q8DWB7_STRMU/1-67M.D-----TQ...AFEQFDVMDSQTLSTVEG.....G.............KVSGGEAVAAIGICATASAA..........
Q8DSB5_STRMU/1-79MMN-----TR...TLEQFDAMDVDMLAAVEG.....G.........NWGQCIVGTGSSALAGGLAGAGTGAAVSAPAAEG
LAFA_LACJO/1-70M..-----.......KQFNYLSHKDLAVVVG.....G.......RNNWQTNVGGAVGSAMIGATVGGTICGP........
A5LX13_STRPN/1-73M..-----..NTKMLSQLEVMDTEMLAKVEG.....G........YSSTDCQNALITGVTTGIITGGTGAGLATLG....
A5MYA6_STRPN/1-54M.N-----TK...MMSQFSVMDNEMLDRIEG.....G.................IFGVDDALFWAG..............
Q2MDB2_BACCE/1-70M..-----.......ENLQMLTEEELMEIEG.....G.....GWWNSWGKCVAGTIGGAGTGGLGGAAAGSAVPV.....
Q9ZEU9_LACPN/1-65M..-----.........YKELTVDELALIDG.....G....KKKKKKVACTWGNAATAAASGAVXGILGGP.........
Q08GC2_LACAM/1-61M..-----..........KQLNSEQLQNIIG.....G........NRWTNAYSAALGCAVPGVKYGKKLGGV........
O85757_9LIST/1-56M..-----........KKELLNKNEMSRIIG.....G...........KINWGNVGGSCVGGAVIGGA............
Q5LYA7_STRT1/1-74M.A-----TQ...TIENFNTLDLETLASVEG.....G...........GCSWRGAGGATVQGAIGGAFGGNVVLPVVGSV
Q8DSA2_STRMU/1-63M.N-----TH...VLEQFDVMDSQVPSAIEG.....G...........GCSWKGADKAGFSGGVGGLIGA..........
Q035H7_LACC3/1-68M..-----......SYNYRQIDDFQLSGVSG.....G....KKKFDCAATFVTGITAGIGSGTITGLAGGP.........
Q08GC0_LACAM/1-68M..-----.......SRVEVLNEEELSAVVG.....GTGGKRARQRKISNCVNYIRMGASSVGGAGAV............
Q08GC3_LACAM/1-75M..-----.......SKGEVLNEDELTAVVG.....G..SKGKGRNNWAGNTIGIVSSAATGAALGSAICGP........
Q9XDR7_9LACO/1-70M..-----.......KNFNTLSFETLANIVG.....G.......RNNWAANIGGVGGATVAGWALGNAVCGP........
Q1J813_STRPF/1-76MMN-----TK...TMEQFEVMNSEMLAGVEG.....G.......WGGWGEAIAGLLGGFAPSPTLDQLNGKWPIRKPSK.

PF03047

CSP4_STRMT/1-31MKN........TVNLDKFVELKEKDLQNIQG-----G-------------------------------------------
Q8RMF1_9STRE/1-31MEK........TVKLEQFKKLTEKELQEIQG-----G-------------------------------------------
Q08GI9_STRMU/1-32MKK.......TPSLKNDFKEIKTDELEIIIG-----G-------------------------------------------
O33645_STRGN/1-38MKKK.NKQNLLPKELQQFEILTDNKLQTVIG-----G-------------------------------------------
O33596_STRAP/1-39MKKLFAKKEVVKKEVVEFKELNDEQLDKIIG-----G-------------------------------------------
A2RMB0_LACLM/1-32MEN.......VKNSLELFTELTDEELENIHG-----G-------------------------------------------
CSP_STROR/1-31MKN........TEKLEQFKEVTEAELQEIRG-----G-------------------------------------------
Q030T1_LACLS/1-30MAE.........DSLKDFQTLGDNELMEIKG-----G-------------------------------------------
Q18LC8_STRPY/1-31MNN........KKTKNNFSTLSESELLKVIG-----G-------------------------------------------
O33615_STRCV/1-39MKKIFSKKEITKVEVESFKELTDEQLNKIVG-----G-------------------------------------------
A5LA85_STRPN/1-31MDK........KQNLTSFQELTTTELNQITG-----G-------------------------------------------
Q8RTK8_9LACO/1-25MKK..............FKELKENELTAITG-----G-------------------------------------------
Q02VE6_LACLS/1-32MKT.......QELNLKQFVMLSEKELQEISG-----G-------------------------------------------
Q93R18_9LACT/1-32MKN.......SEHDLKPFKILSDKELQEVNG-----G-------------------------------------------
A8B010_STRGC/1-38MKKK.NKQNLLPKELQQFEILTERKLEQVTG-----G-------------------------------------------
A5LBY3_STRPN/1-31MKN........TVKLEQFVALKEKDLQKIKG-----G-------------------------------------------
Q9RMH8_LACCU/1-30MES.........NKLEKFANISNKDLNKITG-----G-------------------------------------------
O33617_STRCR/1-35MKN....TQKNFKTIAQFPVLNEKELKEVLG-----G-------------------------------------------
Q8DSB2_STRMU/1-30MNT.........QKLNQFETMDTETLATIEG-----G-------------------------------------------
Q03J26_STRTD/1-30MAN.........NTINNFETLDNHALEQVVG-----G-------------------------------------------

PF04369

LCNA_LACLC/1-60M-----------KNQLNFNIVSDEELSEANG-----G-------------KLTFIQSTAAGDLYYNTNTHKY--------
Q9RPV5_LEUME/1-53M-----------QDKTNFKILSDSELSTISG-----G-------------.......KGVLGWLSMASSALT--------
LCNB_LACLC/1-60M-----------KNQLNFNIVSDEELAEVNG-----G-------------SLQYVMSAGPYTWYKDTRTGKT--------

PF04604

Q48WM6_STRP1/1-48MKNSKD......ILTNAIEEVSEKELMEVAG-----G-------------------KK.GSGWFATITD-----------
A0FL76_9ENTE/1-51MMNAT.......ENQIFVETVSDQELEMLIG-----G-------------------A..GRGWIKTLTK-----------
Q09I51_STRSL/1-56MKSTNNQSIAEIAAVNSLQEVSMEELDQIIG-----A-------------------...GNGVVLTLTH-----------
LANB_STRP9/1-50MTKEH.......EIINSIQEVSLEELDQIIG-----A-------------------G..KNGVFKTISH-----------
A0SXQ1_STRMU/1-50MKQSN.......EMLELIQEVSLDELDQVIG-----G-------------------M..GKGAVGTISH-----------
O85355_BUTFI/1-47MNK.........ELNALTNPIDEKELEQILG-----G-------------------...GNGVIKTISH-----------
A0SXQ2_STRMU/1-53MKKGTQLYL...EALEALQEIKVEELDTFIG-----G-------------------...GGRASNTISS-----------
LANA_STRMU/1-53MNKLNS......NAVVSLNEVSDSELDTILG-----G-------------------NRWWQGVVPTVSY-----------
LANA_RUMGN/1-47MRN.........DVLTLTNPMEEKELEQILG-----G-------------------...GNGVLKTISH-----------
P71449_9LACT/1-50MKEQ........NSFNLLQEVTESELDLILG-----A-------------------KG.GSGVIHTISH-----------
A6MER2_STRMC/1-53MKNNNKICQ...DALESLQELKLEEVDELLG-----G-------------------...AGHGVNTISA-----------
Q50848_MICVA/1-46MT..........NAFQALDEVTDAELDAILG-----G-------------------...GSGVIPTISH-----------
LANNA_STAWA/1-56MENSKVMKDI..EVANLLEEVQEDELNEVLG-----A-------------------KK.KSGVIPTVSH-----------
O31051_STRPY/1-51MEEKMCL.....GALNALQEFQIEELDNLLG-----G-------------------...RGHGVNTISA-----------
Q09II3_STRSL/1-55MAKQQMNLVEI.EAMNSLQELTLEELDNVLG-----A-------------------...GGGVIQTISH-----------

PF08129

Q9L9U6_ENTFL/1-57M--------------KQYKVLNEKEMKKPIG-----G-----------ESVFSKIGNAVGPAAYWILKG-----------
Q8VPA2_ENTFL/1-57M--------------KQYKVLNEKEMKKTIG-----G-----------ESVFSKIGNAVGPAAYWILKG-----------

PF10439

Q8DVP7_STRMU/1-72..VGTVSGA......ALGGWSGAAVGA
A3FKG3_9LACO/1-67..VSVGTGA......LIGASAGAIGGS
Q8DSA3_STRMU/1-59..VGDPVGV........AMAAGTIAAG
Q5FI73_LACAC/1-70..VGALGGA......LFGGSMGVIKGS
Q73F42_BACC1/1-68..YGGGVGA......LAGGVAGGIGSC
A1KWV2_STAAU/1-68..ACAVVGA.HYGPIIWAGVSGATGAF
Q6XVH3_LACSK/1-59..AGGPAGA......FVGAHVGVIAGS
O85756_9LIST/1-67..LGAIPGA......FVGAHFGVIGGS
O54454_STRTR/1-72..VGALPGA......FVGAHVGAIAGG
Q9ETC8_STRPN/1-84G.ACGYIGA.KFGVDLWAGVTGATGGF
Q5M2W2_STRT2/1-71..QGAVAGA......AGGAIVGGVGYG
Q08GB9_LACAM/1-73..VGAFGGA......MFGGSIGIIKGS
Q8KWI0_9LACO/1-60.....PAGI......VGGANLGMVGGA
Q8DS95_STRMU/1-75..GTGAFGA......IAGGIGGALNSC
Q03D40_LACC3/1-67..AGVTIGG......LYGTLSGILTGY
O54455_STRTR/1-64..AAAGVGC......LVGSGKAIINGL
LAFX_LACJO/1-59..WGMAICG......VGGAAIGGYFGY
A5MPT6_STRPN/1-63..WGAAIGG......IGGAVVCGYLAY
Q9A139_STRP1/1-69..VGGVAGA......FAGAHVGAIAGG
Q8DWB7_STRMU/1-67..IGGLAGATLVTPYCVGTW.GLIRSH
Q8DSB5_STRMU/1-79GGLGPIAGA......AIGWDLGAISGA
LAFA_LACJO/1-70..ACAVAGA.HYLPILWTAVTAATGGF
A5LX13_STRPN/1-73..VAGLAGA......FVGAHIGAIGGG
A5MYA6_STRPN/1-54..LGYVAGS......IVDTAIDDFTNQ
Q2MDB2_BACCE/1-70..IGTGIGG......AIGGVSGGLTGA
Q9ZEU9_LACPN/1-65..TGALAGA......IWGVSQCASNNL
Q08GC2_LACAM/1-61..WGAVIGG......VGGAAVCGLAGY
O85757_9LIST/1-56..LGGLGGA......GGGCITGAIGSI
Q5LYA7_STRT1/1-74..PGYLAGG......VLGGAGGTVAYG
Q8DSA2_STRMU/1-63..GGNPVGG......VLGIA.GGLDAY
Q035H7_LACC3/1-68..FGIIGGA......VVGGNLGAVGSA
Q08GC0_LACAM/1-68..VGGLGGA......LLGGSLGVIAGS
Q08GC3_LACAM/1-75..GCGFVGA.HWGAVGWTAVASFSGAF
Q9XDR7_9LACO/1-70..ACGFVGA.HYVPIAWAGVTAATGGF
Q1J813_STRPF/1-76..PCSPYGT........GGTPNTCNGL

PF03047

CSP4_STRMT/1-31--EIRQTHN------------------
Q8RMF1_9STRE/1-31--DWRFLNS------------------
Q08GI9_STRMU/1-32--SGSLSTF------------------
O33645_STRGN/1-38--SQKGVYA------------------
O33596_STRAP/1-39--DSRIRMG------------------
A2RMB0_LACLM/1-32--QNMSMTD------------------
CSP_STROR/1-31--DKRLPYF------------------
Q030T1_LACLS/1-30--DLSTNIR------------------
Q18LC8_STRPY/1-31--DIFKLVI------------------
O33615_STRCV/1-39--DSRIRMG------------------
A5LA85_STRPN/1-31--EWWEELL------------------
Q8RTK8_9LACO/1-25--SFVGYYL------------------
Q02VE6_LACLS/1-32--GGWGSAF------------------
Q93R18_9LACT/1-32--MSWWQAI------------------
A8B010_STRGC/1-38--DVRSNKI------------------
A5LBY3_STRPN/1-31--EMRLSKF------------------
Q9RMH8_LACCU/1-30--GFWGGLG------------------
O33617_STRCR/1-35--DLRNIFL------------------
Q8DSB2_STRMU/1-30--MTWAEIG------------------
Q03J26_STRTD/1-30--SGWMDYI------------------

PF04369

LCNA_LACLC/1-60--VYQQTQN------AFGAAANTIV--
Q9RPV5_LEUME/1-53--GPQQPNS------PWLAKIKNHK--
LCNB_LACLC/1-60--ICKQTID------TASYTFGVMA--

PF04604

Q48WM6_STRP1/1-48--DCPN...----------..SVFVCC
A0FL76_9ENTE/1-51--DCPNVIS----------SICAGTII
Q09I51_STRSL/1-56--ECNL.AT----------WTKKLKCC
LANB_STRP9/1-50--ECHL.NT----------WAFLATCC
A0SXQ1_STRMU/1-50--ECRY.NS----------WAFLATCC
O85355_BUTFI/1-47--ECHM.NT----------WQFIFTCC
A0SXQ2_STRMU/1-53--DCRW.NS----------LQAIFSCC
LANA_STRMU/1-53--ECRM.NS----------WQHVFTCC
LANA_RUMGN/1-47--ECNM.NT----------WQFLFTCC
P71449_9LACT/1-50--EVIY.NS----------WNFVFTCC
A6MER2_STRMC/1-53--ECRW.NS----------LQAIFSCC
Q50848_MICVA/1-46--ECHM.NS----------FQFVFTCC
LANNA_STAWA/1-56--DCHM.NS----------FQFVFTCC
O31051_STRPY/1-51--ECRW.NS----------LQAIFTCC
Q09II3_STRSL/1-55--ECRM.NS----------WQFLFTCC

PF08129

Q9L9U6_ENTFL/1-57--LGNMSDV-------NQADRINRKKH
Q8VPA2_ENTFL/1-57--LGNMSDV-------NQADRINRKKH

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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