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84  structures 3700  species 4  interactions 6906  sequences 86  architectures

Clan: HRDC-like (CL0426)

Summary

HRDC-like superfamily Add an annotation

Superfamily includes HRDC domain from helicases, RNA polymerase II subunit RBP4, RNase D C-terminal domains, and EXOSC10 HRDC domain-like families.

This clan contains 3 families and the total number of domains in the clan is 6906. The clan was built by P Coggill.

Members

This clan contains the following 3 member families:

Helicase_Sgs1 HRDC RNA_pol_Rpb4

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
HRDC (PF00570) 6087 (88.1%) View
RNA_pol_Rpb4 (PF03874) 790 (11.4%) View
Helicase_Sgs1 (PF11408) 29 (0.4%) View
Total: 3 Total: 6906 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 4 interactions for this clan. More...

Interacting families
A B
RNA_pol_Rpb4 S1
SHS2_Rpb7-N
HRDC HRDC
DNA_pol_A_exo1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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