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97  structures 918  species 5  interactions 3101  sequences 27  architectures

Clan: PF (CL0431)

Summary

Profilin-like superfamily Add an annotation

The families here all show the Profilin-like fold, and represent both the Profilin (actin-binding protein) (55770) and the Roadblock/LC7 domain-type (103196) superfamilies.

This clan contains 3 families and the total number of domains in the clan is 3101. The clan was built by A Bateman.

Members

This clan contains the following 3 member families:

MAPKK1_Int Profilin Robl_LC7

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Robl_LC7 (PF03259) 1879 (60.6%) View
Profilin (PF00235) 1081 (34.9%) View
MAPKK1_Int (PF08923) 141 (4.5%) View
Total: 3 Total: 3101 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 5 interactions for this clan. More...

Interacting families
A B
Robl_LC7 Robl_LC7
MAPKK1_Int
Profilin Actin
Profilin
MAPKK1_Int Robl_LC7

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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