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0  structures 389  species 0  interactions 3724  sequences 141  architectures

Clan: G-PATCH (CL0449)

Summary

DExH-box splicing factor binding site Add an annotation

This superfamily is characterised by domains which are related to the G-patch domain in proteins with RNA-binding/splicing activity. This domain affects RNA-splicing by binding to a DExH-box splicing factor.

This clan contains 2 families and the total number of domains in the clan is 3724. The clan was built by P Coggill.

Literature references

  1. Silverman EJ, Maeda A, Wei J, Smith P, Beggs JD, Lin RJ;, Mol Cell Biol. 2004;24:10101-10110.: Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. PUBMED:15542821 EPMC:15542821
  2. Boon KL, Auchynnikava T, Edwalds-Gilbert G, Barrass JD, Droop AP, Dez C, Beggs JD;, Mol Cell Biol. 2006;26:6016-6023.: Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. PUBMED:16880513 EPMC:16880513

Members

This clan contains the following 2 member families:

G-patch G-patch_2

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
G-patch (PF01585) 3420 (91.8%) View
G-patch_2 (PF12656) 304 (8.2%) View
Total: 2 Total: 3724 Clan alignment
 

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Family relationships

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Species distribution

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