Sequence alignment for CL0449

PF12656

SPP2_MAGO7/193-264AGAKEEEAFKQNFRDAPDVSTLE..DYEEMPVEEFGAA..LLRGMGWD.......---GKPRG-----PK..........
A8N6C4_COPC7/171-249TPISEADALKQDVDELPDVATLE..DYERVPVSQFGAA..MLRGMGWK......E---GQAAS-----RKGKGM......
B0X5P1_CULQU/132-210DNFVVPLKPEDLPLEGARESTLD..DYEAIPIESFGMA..MLRGMGFK......E---DPAKK-----KDKDDK......
C5DW30_ZYGRC/97-169NGQEHINLKLPDEDSLPEITKKE..EYEKVPVEEFGEA..LLRGMGWDG....KE---DERNG-----GD..........
C5DLQ4_LACTC/105-187REALALSRKPNSVVHLPTETAQE..EYETVPVEEFGDA..LLRGMGWNG...ELE---NEVVA-----KSAGKS......
SPP2_DEBHA/188-265PIPSEDEIVEQDISSKPDEDSIE..QYKEVPVDQFGAA..LLRGMGWK......Q---NKGKN-----IESAGK......
A9TPY5_PHYPA/144-222LKEIEDQKLKEDLANLPEEATLD..QYEELPVEEFGEA..LLRGMGWE......K---GKPIG-----RNSKTI......
A6ZNZ2_YEAS7/73-156IKLSENADTKKNDAPLVEYVTEK..EYNEVPVEEFGDA..LLRGMGWESDSERDS---KGDKT-----QSRNKD......
B9GZX9_POPTR/117-195SEDVLLEKLRYDLKRLPEDRGFE..EFEEMPVEDFAKA..LLKGYGWH......E---GRGVG-----KNSKED......
B6S330_9BILA/142-222ETNSSLKSEKAEEKEEEEEKEVENANYDEVPIEDFGMA..VLRGMGYK......E---DSGLG-----ISNKRN......
SPP2_SCHPO/164-235NVVNEKDAYRKDIDELPEPSNMK..DYSEIPVEEFGAA..MLRGMGWN.......---GQLSS-----KD..........
A5E6K4_LODEL/102-185SDSTTIIRRRHYVSDSESEPDQD.......AVDEFGAA..FLRGLGYD......E---DEDED-----EDKNGRAAGP..
C5MIB8_CANTT/93-173QQSFIKKRTMNNFDSDDESEESD..NEKRIPVEEFGAA..FLRGLGWN......D---NNDEE-----KDKKEE......
A7RK31_NEMVE/122-200ISGSDKDAVKMDIALRPEPTTLE..EYEAMPVSAFGAA..MLRGMGWK......K---GQAIG-----GSVKGL......
Q5CPI8_CRYPI/99-173IEILLNKKNSSNDTNEDDLDSSTNKDNFRIPVDKFGIA..MLRGMGYN......P---EIHNT-----KPK.........
A6S9P1_BOTFB/213-284DLVTEEDAYKRAIASAPDISTLE..DYDAVPVEEFGAA..LLRGMGWD......G---KERKG-----GG..........
B8N9T4_ASPFN/236-318GRYDEGTSFRADIASRPESATLD..QYNAIPVEEFGAA..LLRGMGWK......E---GQAVG-----KGKYG.SS....
SPP2_USTMA/198-276HQETESELLQHDIDSRPEAPTLD..DYAATPIDQFGMA..LLRGMGWK......E---GMGAG-----KGGKGP......
B4G4A4_DROPE/132-208KLVLPAVKADDLPLEGAKEASLD..DYESIPIQQFGLA..MLRGMGWV......D---PPP..-----KKKGSA......
Q4N0N3_THEPA/164-241NNNKTDVAVDDRVDNLGKMLRVDKSQYDKVPVENFGMA..MLMGMGYN......P---NNTQE-----NDNTMK......
A7UVL9_ANOGA/126-200ANFVVPLRAELRLEDSARQSNLD..DYESVPIEQFGVA..MLRGMGFT......G---DPTSE-----SDKLTP......
B2AXP4_PODAN/191-263GASSQPKKRKLNLESEDPDREPQAEDYEAVPIDDFGAA..LLRNFGWN.......---GQMQG-----KV..........
Q0UX49_PHANO/177-254PLHNDEDAFQSDLRSAPDAPTLD..AYEATPIEGFGAA..LLRGMGWK......D---SDAAG-----KNGAPA......
SPP2_NEUCR/220-293SSTASKRKRSHSPSSHDRDRSPDHSDYRAVPIDDFGAT..LLKQFGWD.......---GKMRG-----KVK.........
Q2H706_CHAGB/194-266ALMGSRIPKRKHLDSDAADREPRPEDYRSVPIDDFGAH..LLRNFGWD.......---GKMKG-----KV..........
A9V613_MONBE/153-231ERLDDAEKFKRDMQLRPAELSLQ..EYDRVPIEQFGTA..MLRGMGWQ......K---GEAIG-----GTNKGL......
A8Q836_MALGO/199-277QQPNEEEMFHRDVGTRPNEPTLD..DYQSMPVEEFGAA..MLRGMGWK......E---GMGAG-----KRRNGP......
Q54GS9_DICDI/195-274KYENETDKFKHDVESRPDESNLD..DYEETPVSIIGEA..LLRGMGWV......P---GKSIG-----STNKGL......
B6JY96_SCHJY/211-282PEDSAAALFKKQMGELPSASQVE..EYAEMPVEEFGAA..MLRGMGWN.......---NEYSA-----KD..........
A1CXM0_NEOFI/231-316VRLDETGSFRVDVASRPEPATLD..QYNAIPVEEFGAA..LLRGMGWK......E---GQLIG-----RGKYG.TSAT..
B6ABN7_CRYMR/110-184LKRKNQKQNEANDSLSKTSSELVYLKESKIPIDSFGMA..MLKGMGYD......P---SIHKT-----RPK.........
B8MKA9_TALSN/205-287SRYDETSSFRADVATRPDQASLD..AYDAVPVEEFGAA..LLRGMGWK......E---GQAIG-----RGNYG.NT....
B9WN42_CANDC/87-167KVETTKQSMIKALETENSEDESS..DNRKIPIDEFGAA..FLRGLGWK......E---EEEKT-----KDNNKS......
B2VZL7_PYRTR/177-251PAQTEEEEYINDIHNAPDGPTLE..AYEATPIEGFGAA..LLRGMGWK......G---EETTG-----NS..........
Q10NZ4_ORYSJ/153-231SGDLMLRRYKEDMASLPDHRGLD..EFRDVPVEGFGAA..LLAGYGWS......E---GKGIG-----RNNKGD......
Q16LD9_AEDAE/133-209DSMVVPLKPEDLPLDGGRESTMD..DYESVPIEKFGLA..MLRGMGWK......E---DPNAP-----KKSDKF......
A0EB76_PARTE/3-83NDVPVQERKNFTLSSKPDNTEDT...YSKAPVSQFAQN..LLSKMGFQ......E---GQPIG-----KNSQKSS.....
A7THM0_VANPO/109-188QHFDVTKMSHLVNGSLPETTTIE..EYEEVPVEEFGEA..LLRGMGWSG...QLD---DEKKS-----KKNSTL......
SPP2_EMENI/228-312GHNSETRSFRADVAARPESATLE..QYNTIPVEEFGAA..LLRGMGWK......E---GQAVG-----KGKYG.SAD...
Q55Z15_CRYNB/211-282KPLSEEDALKRDIEALPEESTLD..DYAAIPVSAFGEA..MARGMGWN.......---PSAQG-----TK..........
A8INC7_CHLRE/136-213AAAAEEKAYKDSVEDLPEVADLD..AYEAMPIEEFGRA..MLRGMGWE......E---GMGVG-----RNRKQ.......
Q8LEJ3_ARATH/110-188VEKMLLKSMRTDLESLPDAPEQE..DFESFPVDGFGEA..LLAGYGWK......P---GQGIG-----LKAKED......
B3RYJ9_TRIAD/127-205RVKGIESSEKLDIAMRPETSSLE..DYENMPISNFGQA..MLRGMGWS......V---GQGIG-----KTNKQV......
B7P250_IXOSC/140-218VPEGFETDEKVDVSLRAEEPSQE..DYESVPIEEYGLA..MLRGMGWH......P---GKPIG-----ARCTEV......
B7FWT3_PHATC/114-191TFQQETEQFKADIDTLPEEPTLDSEQYRRVPIGDFGAA..MLRGMGWS.......---GDDVS-----LKSGGD......
Q5M7L0_XENTR/127-205IPDGYEDGEKVDVSLRPDSAEAA..DYDAVPVEYYGMA..MLRGMGWK......E---GEGIG-----RTFKQD......
C1EGP9_MICSR/141-219LAEKELQAFKEDVEDLPEQATLD..DYEQMPIEDFGAA..MLRGMGWE......E---GKPVG-----RNNNGM......
C5JH42_AJEDS/255-338ERFDETKSFRADVASRPEPASLA..AYSAIPVEEFGAA..LLRGMGWK......D---GEPIG-----RGKYG.NTN...
Q6C7F8_YARLI/163-236QEQRELQALRQDINALPDMASVE..DYASMPVEDFGAA..LFRGMESA......L---PQRVV-----TQ..........
C4WWW6_ACYPI/115-192DTKIVEVPLIINSQEGMEMSTAE..DYESIPIDKFGLA..MLRGMGWK......P---TKGVG-----KNSQ........
Q01CV9_OSTTA/230-308LHEKELQAFKEDMEDLPEQASIE..EYEDMPIEDFGKA..MLRGMGWE......E---GKAVG-----RMHRGM......
B6HVD7_PENCW/232-317VHYSELGSFRTDVASRPEPANLD..AYNAIPVEEFGAA..LLRGMGWK......D---GQAIG-----RGNYS.SATA..
B9SAH9_RICCO/128-206TENIMLEKLRYDLERLPEDRGFD..EFKDVPVEGFGAA..LLAGYGWR......E---GRGIG-----RNAKED......
Q4S5Z8_TETNG/138-216VPDGFEDGDHVKVDLRPESSAEA..DYEQVPVEAYGYA..MIRGMGWK......K---SEGIG-----RTFKQN......
Q1JSM6_TOXGO/344-421TETSEKELLQEELNLLPDALSATSAEYSRIPVSEFGLA..MLRGMGYD......A---EKKEE-----TTKGAA......
Q4UCY1_THEAN/198-272LENKNNLESINNVENIKKILKLDKRQYEKVPVENFGIQ..MLMGMGYN......P---KINKE-----NNK.........
C3Z963_BRAFL/123-201APEGFETDSKLDVSIRPDEASLD..DYEAMPVEAFGMA..ALRGMGWT......P---GEGIG-----RTFKQH......
B8P0H2_POSPM/231-309PAPSEDDAYRQDVEELPEPATLD..DYERVPVSQFGAA..LLRGMGWT......P---GTAAS-----KKQKGP......
A7AWB1_BABBO/194-268IEQASNTVPILLRGKRDHEDTDVEPSYENVAVEEFGLA..MLLGMGFN......P---ATNTN-----KPK.........
A7RHK5_NEMVE/445-525KKVSPSSKVKKARKTLPASEVAVAQATLPIPEHNIGNQ..MLREMGWV......P---GKGLG-----PNQSGR......
B7PD50_IXOSC/721-803PEPPQTGTVHKEKVARPMPAQQNYEEPTKAGIGEDNIGNKMLKAMGWS......E---GQGLG-----KSNTGT......
A3GIA1_PICST/183-261VIPIDDAQFQRSLDEDPDEDSAE..EYEKVPVEQFGAA..LLRGMGWK......P---ETKPK-----NTTVDN......
C5FXX0_ARTOC/262-342SAYDETKSFRRDIESRPAPASLS..AYNAVPVEEFGAA..LLRGMGWK......E---GQPVG-----RGNYG.N.....
B6KRN4_TOXGO/3-70KKFYDRLLKGSGVQSRPFHSS.............FGAS..ILKKFGWE......E---GQGLG-----RENTGR......
SPP2_KLULA/93-170ESKFDFKGPSALRNNIPEKTNEE..EYEEVPVEGFGTA..LLRGMGWD......P---SAEND-----SSSEKS......
C4Y015_CLAL4/126-202KSVDDTSNLTIKMGDNDSAEDIVEEDYENVPVEQFGAA..LLRGMGWK......E---NDTKS-----SKGVD.......
B8CB44_THAPS/244-339PPPNDEEIFKQELAHHAADVDPTSNVYANVSIGDFGSA..LLRGMGWNG....SA---SGNIN-----NNGNSRLGGGAK
C5K841_PERM5/148-216CQVNKRRKTGENANDFDESK.....DAREIPIEEFGMA..MLRGMGFD......K---DKHVQ-----QP..........
MOS2_ARATH/127-205GEQLMLQSLRRDLMSLADDPTLE..DFESVPVDGFGAA..LMAGYGWK......P---GKGIG-----KNAKED......
SPP2_CANGA/70-148KNNIGDDSIVQELEALPEKVEDK..EYEEMPVEEFGAA..MLRGMGWT......D---ENELE-----DSKSHS......
A5DI61_PICGU/122-199NIIDNDSGMVINLEQSDEEKDVEEAEYDKVPVDQFGAA..LLRGMGWK......P---NNKRK-----DSPEPS......
SPP2_ASHGO/96-177KSAAKSGAGVVPLDQLPDPTGLE..EYSEVPVEEFGAA..LLRGMGWDGDEEEIE---GDRRG-----QK..........
MOS2_CAEEL/123-202GENEEESGKGEKIVVEDGRGDTEDADYSAIPIESFGLA..ILRGCNWK......D---GDGIG-----KNPQKV......
A8Q1K8_BRUMA/127-207LVESASLLTQKNGNKVDGEVSDVGADYDSVPIDVFGLA..ILRGCGWR......E---GEGIG-----KTNKKV......

PF01585

VPRT_JSRV/244-288-------------------------------PSPTVTD--LMLDQGLL------P...NQGLG.....KQHQGI------
CHERP_HUMAN/841-889-------------------------------EENKGHQ--MLVKMGWS------G...SGGLG.....AKEQGI------
SON_HUMAN/2305-2349-------------------------------TGGMGAV--LMRKMGWR------E...GEGLG.....KNKEGN------
RBM10_HUMAN/858-902-------------------------------SDNIGSR--MLQAMGWK------E...GSGLG.....RKKQGI------
TFP11_CAEEL/153-197-------------------------------NSNKIMK--MMQAMGYK------P...GEGLG.....AQGQGI------
O41289_MPMV/270-314-------------------------------PNDIVIA--QMLTQGYT------P...GKGLG.....KRENGI------
Q9SW24_ARATH/139-183-------------------------------VDGFGEA--LLAGYGWK------P...GQGIG....LKAKEDV------
PXR1_SCHPO/25-69-------------------------------TNRLGFK--LLSSYGWV------N...GNGLG.....EKQHGR------
YL271_YEAST/41-85-------------------------------IMPRGYK--MMENMGYK------E...GETLG.....SNESAL------
SP382_YEAST/61-106-------------------------------TYGIGAK--LLSSMGYV------A...GKGLG.....KDGSGI------
VPRT_SRV1/270-314-------------------------------PSDIVTA--QMLAQGYS------P...GKGLG.....KNENGI------
Q9VPY4_DROME/935-979-------------------------------SSNVGSR--LLQKMGWS------E...GQGLG.....RKNQGR------
YG0G_SCHPO/112-160-------------------------------PKSLGYR--VLSQYGWS------PQGDTAGLG.....LENQGR------
RBM6_HUMAN/1051-1095-------------------------------TSSKGGC--VQQATGWR------K...GTGLG.....YGHPGL------
MTR1_DROME/25-69-------------------------------YSNKAME--MMKKMGYE------N...DKGLG.....KSNQGR------
O65245_ARATH/52-95-------------------------------LEDVEQA--SLDKMGWK------....GKGLG.....KQEQGI------
Q9TYS1_CAEEL/637-681-------------------------------TGGIGRL--MLEKMGWR------P...GEGLG.....KDATGN------
SUGP1_HUMAN/562-607-------------------------------VENIGYQ--MLMKMGWK------E...GEGLG.....SEGQGI------
Q9SH49_ARATH/15-59-------------------------------KDSAAFK--LMKSMGWE------E...GEGLG.....KDKQGI------
Q22178_CAEEL/73-120-------------------------------HESKGFA--LMAKMGFK------P...GMTLGK..QREDEIRI------
GPTC1_CAEEL/145-194-------------------------------SNSIGVR--MLRSMGWR------E...GRGIGLANVKQKQKRG------
GPAN1_MOUSE/271-315-------------------------------TSSPGFR--LLLRGGWE------P...GMGLG.....PRGEGR------
RBM5_HUMAN/743-787-------------------------------HSNIGNK--MLQAMGWR------E...GSGLG.....RKCQGI------
PXR1_YEAST/25-70-------------------------------TSRFGHQ--FLEKFGWK------P...GMGLG....LSPMNSN------
DR111_ARATH/214-258-------------------------------QMTAAQR--MMAKMGWK------Q...GQGLG.....KSEQGI------
O94028_CANAX/83-127-------------------------------KYGIGAK--LLMKMGYQ------K...GKGLG.....VNQEGI------
YKR3_SCHPO/115-159-------------------------------TTGFGAK--MLEKMGYK------Q...GQGLG.....ANAEGI------
VPK4_HUMAN/111-155-------------------------------YSPTSQK--IMTKRGYI------P...GKGLG.....KNEDGI------
Q20966_CAEEL/209-254-------------------------------GLGIAAN--IMKRHGYK------E...GAGLG.....KSEQGM------
Q9VI83_DROME/72-116-------------------------------ADNKGFQ--LLAKMGYK------A...GSGLG.....ITSDAR------
Q61213_MOUSE/783-827-------------------------------YSAKAKN--IMAKMGYK------E...GKGLG.....HQEQGR------
YDMD_SCHPO/490-534-------------------------------TSNVSMK--MLNSMGWN------K...GSGLG.....TNENGI------
Q9SF87_ARATH/635-679-------------------------------TRGFGSK--MMAKMGFI------D...GGGLG.....KDGKGI------
C3H22_ARATH/300-344-------------------------------TRGIASK--MMASMGYR------E...GMGLG.....VSGQGI------
Q18418_CAEEL/248-292-------------------------------GGGVGMK--LMMKMGYK------V...GEGLG.....KRSDGI------
Q9VNC5_DROME/230-275-------------------------------EDNIGFQ--MLQKLGWK------E...GQGLG.....QDGAGI------
GPAN1_CAEEL/263-307-------------------------------PSNIGYR--LMCASGWT------E...EQGLG.....RNSDGQ------
O01886_CAEEL/244-294-------------------------------QKGIGGS--MLAKMGWK------P...GTGLG.....KNEQGR------
VPRT_SMRVH/275-319-------------------------------PNDTVMT--QMLSQGYL------P...GQGLG.....KNNQGI------
SQS1_YEAST/720-765-------------------------------NENIGRR--MLEKLGWK------S...GEGLG....IQGNKGI------
Q9SF87_ARATH/736-780-------------------------------TTGFGSR--MMARMGFV------E...GSGLG.....RESQGI------
Q22705_CAEEL/26-70-------------------------------DQKLSKK--LMEKMGWS------E...GDGLG.....RNRQGN------
TFP11_HUMAN/149-193-------------------------------TKGIGQK--LLQKMGYV------P...GRGLG.....KNAQGI------
Q9SHG6_ARATH/200-243-------------------------------TKGIGMK--LLEKMGYK------....GGGLG.....KNQQGI------
SPF45_MOUSE/235-279-------------------------------GGTVAHK--IMQKYGFR------E...GQGLG.....KHEQGL------
YAB4_SCHPO/252-301-------------------------------KENVALK--MLQRCGWK------E...GQGLG.....QHNQGI------
GPTC1_DROME/153-201-------------------------------RDKVAVR--ILKSMGWK------P...GQGVGPR.QTRKEKRQ------
ZGPAT_DROME/312-356-------------------------------TRGIGSK--LMEKMGYI------H...GTGLG.....SDGRGI------
Q9XWG6_CAEEL/433-477-------------------------------SGNVGFK--LLKSMGWS------E...GQGLG.....KEKQGH------
NKRF_HUMAN/551-594-------------------------------EDNIGNQ--LLRKMGWT------....GGGLG.....KSGEGI------
TFP11_DROME/167-211-------------------------------TRGIGAK--LLLQMGYE------P...GKGLG.....KDLQGI------
Q9VHB0_DROME/705-749-------------------------------TGGMGMA--LLQKMGWK------P...GEGLG.....RCKTGS------
GPAN1_DROME/240-284-------------------------------AKNRGLQ--LMVKQGWD------Q...EHGLG.....PSQSGR------
P89941_9BETR/85-129-------------------------------ESSTGRR--IMYKKGYQ------....ERGLG.....SRE.GR------
O59861_LENED/98-141-------------------------------PSNKGFA--MLQNSGWN------E...GEALG.....QDVVRR------

PF12656

SPP2_MAGO7/193-264.........TKDVKRRPN.Q------MGLGAKDLKGQ
A8N6C4_COPC7/171-249.......IEPYIPAARPA.L------LGIGAKEQEVY
B0X5P1_CULQU/132-210.......LLPEGPMMRPK.G------LGLGAERAPKD
C5DW30_ZYGRC/97-169...........SPAPRLP.F------LGIGAKALPNH
C5DLQ4_LACTC/105-187......KPVLPHEQFRPS.L------LGLGAKASQNT
SPP2_DEBHA/188-265.........PLLERRKKGVL------LGIGAKAVEDE
A9TPY5_PHYPA/144-222.......VTVPELVRRPG.T------LGLGAVPVPPK
A6ZNZ2_YEAS7/73-156........VSNVSQIHPD.G------LGIGAKLNKAI
B9GZX9_POPTR/117-195.......VQVKQYTKRTD.K------EGLGFLAASHD
B6S330_9BILA/142-222.......VDVFVPDMRPR.G------LGLGADRKVLE
SPP2_SCHPO/164-235.........AFDVNQRPT.F------LGMGAKPVDSE
A5E6K4_LODEL/102-185..SNKKQFDTAARNRRLGVT------LGIGAKVDNLE
C5MIB8_CANTT/93-173......KQQEILNHRQKGIT------LGIGAKPVDHE
A7RK31_NEMVE/122-200.......AEPIEYIPRSK.G------LGLGAEVRAEM
Q5CPI8_CRYPI/99-173...........IFKKRNYNQ------SGLGADKEIGS
A6S9P1_BOTFB/213-284..........KEVKRRQN.L------LGLGAKELKDA
B8N9T4_ASPFN/236-318....AVLDKPRIPERRPG.F------LGIGAKDASGG
SPP2_USTMA/198-276.......QQAAEPRKRAA.L------LGLGAKERPTG
B4G4A4_DROPE/132-208.......PVDEAPFLRPK.G------MGLGADKALKP
Q4N0N3_THEPA/164-241...........KYTKRIYER------GGLGTDTIMQN
A7UVL9_ANOGA/126-200...........GPELRPK.G------LGLGADKTIKG
B2AXP4_PODAN/191-263...........KEVKRHADL------AGLGARNLKAG
Q0UX49_PHANO/177-254........KIKQVKPRPA.L------LGIGAKEDAAA
SPP2_NEUCR/220-293...........EVTHKHANL------AGLGAKDAKGA
Q2H706_CHAGB/194-266...........KEVTRHANL------TGLGAKDAKGA
A9V613_MONBE/153-231.......VEPIEFVPRPS.G------LGLGATRDLSL
A8Q836_MALGO/199-277.......AHAPIIQRRAA.L------LGLGAKERASP
Q54GS9_DICDI/195-274.......VEPIEYIKRPGFR------LGLGAKPMDDD
B6JY96_SCHJY/211-282.........AFDVNRRPT.F------LGMGAKPLEEE
A1CXM0_NEOFI/231-316...DDRSQTPRIPERRPG.F------LGIGAKDVSGG
B6ABN7_CRYMR/110-184...........LYKKRTYDQ------GGLGSDLIIDS
B8MKA9_TALSN/205-287....SAANEARVPQRRPG.F------LGIGAKDIGGA
B9WN42_CANDC/87-167......TNLQNLSHRKQGIT------LGIGAKPIDEE
B2VZL7_PYRTR/177-251.......TKSKEVKRRPA.L------LGVGAKADAAV
Q10NZ4_ORYSJ/153-231.......TKVVEYDRRAG.T------QGLGYNPSEAD
Q16LD9_AEDAE/133-209.........PEGPVQRPK.G------MGLGAERAPKD
A0EB76_PARTE/3-83.....ALLKPIEFLSRGD.R------EGLGVNPMKTY
A7THM0_VANPO/109-188.........LPHEKARAE.F------AGIGATVPVTY
SPP2_EMENI/228-312...PSRASTPHIPARRPG.F------LGIGAKDVSNG
Q55Z15_CRYNB/211-282.........IHEPKLRPA.L------LGLGATALETP
A8INC7_CHLRE/136-213.......VDAIEYVRRPE.R------LGLGAQPVKVS
Q8LEJ3_ARATH/110-188.......VKIVEYEKWSG.N------EGFGFGKSDKA
B3RYJ9_TRIAD/127-205.......IKPIEFTPRYK.G------LGLGAERLVES
B7P250_IXOSC/140-218.......AKPIEAVLRPR.G------LGLGAESKLSK
B7FWT3_PHATC/114-191.........AELAISRPH.R------LGLGATPKLDA
Q5M7L0_XENTR/127-205.......VKPLEQKLRPK.G------LGLGADRSALK
C1EGP9_MICSR/141-219.......VAAVEFVPRSG.R------LGLGADPAPSK
C5JH42_AJEDS/255-338....ARATKPRITERRPG.Y------LGIGAKELPGN
Q6C7F8_YARLI/163-236........AAKVPDKRPA.L------LGLGAKTLEEH
C4WWW6_ACYPI/115-192......IIAASLPEIRSK.G------MGLGADKLIKS
Q01CV9_OSTTA/230-308.......VEAVEFIPRAA.R------LGLGAQPAEKD
B6HVD7_PENCW/232-317...AERAKNPRVPERRPG.L------LGIGAKDSSGG
B9SAH9_RICCO/128-206.......VKVKQYTKRTD.K------EGLGFVASVVS
Q4S5Z8_TETNG/138-216.......VTAVEHQVRPK.G------LGLGADRSLIK
Q1JSM6_TOXGO/344-421...........PKRKRTYNR------AGLGSEEEVER
Q4UCY1_THEAN/198-272...........KYIKRIYEK------GGLGTDIIMEN
C3Z963_BRAFL/123-201.......VDPLQLQVRPK.G------LGLGAVVRPTE
B8P0H2_POSPM/231-309.......IDPYLPEARPA.L------LGIGAKEKEVF
A7AWB1_BABBO/194-268...........EYKRRAYDR------AGLGADAHMKR
A7RHK5_NEMVE/445-525.......VDPVKATMRPK.G------LGLGHTWPSSK
B7PD50_IXOSC/721-803.......TNIVEVQRRVT.S------AGLGVRGATYG
A3GIA1_PICST/183-261........EKVLQHRQKGVL------VGIGAKAVEND
C5FXX0_ARTOC/262-342.....TPITPRVPERRAG.Y------LGVGAKDISGK
B6KRN4_TOXGO/3-70.......TDCLQIRRREE.N------VGLGHSDASET
SPP2_KLULA/93-170........TLLHEKPHPE.L------VGIGAKLTTAS
C4Y015_CLAL4/126-202...........VSHRQRGVT------LGIGSTPVEKE
B8CB44_THAPS/244-339RLGGSKPTDEEVIKPRPH.R------LGLGATPLPPP
C5K841_PERM5/148-216...........IFTERREGH------VGLGAKVVLPT
MOS2_ARATH/127-205.......VEIKEYKKWTA.K------EGLGFDPDRSK
SPP2_CANGA/70-148.......KKLPHEQIHPE.G------LGIGAKSQEMS
A5DI61_PICGU/122-199...........LENRKKGVV------LGIGAKPVETE
SPP2_ASHGO/96-177......TVLPHEQAGRAE.Y------LGIGASSDVDR
MOS2_CAEEL/123-202........ALKLPNRRPP.G------LGLGATPKNPV
A8Q1K8_BRUMA/127-207.......VPLRISTRRPK.G------LGLGAAIMSKP

PF01585

VPRT_JSRV/244-288-------ILPLDLKPNQD-R......KGLGCF-----
CHERP_HUMAN/841-889-------QDPIKGGDVRD-KWD..QYKGVGVA-----
SON_HUMAN/2305-2349-------KEPILVDFKTD-R......KGLVAV-----
RBM10_HUMAN/858-902-------VTPIEAQTRVR-G......SGLGAR-----
TFP11_CAEEL/153-197-------VEPVQAQLRKG-R......GAVGAY-----
O41289_MPMV/270-314-------PQPILVSGQFD-K......KGFGNF-----
Q9SW24_ARATH/139-183-------KIVEYEKWSGN-.......EGFGFG-----
PXR1_SCHPO/25-69-------IHNIKVSLKDD-T......LGIGAK-----
YL271_YEAST/41-85-------KEPIKVEINTK-R......RGIRAE-----
SP382_YEAST/61-106-------TTPIETQSRPM-H.....NAGLGMF-----
VPRT_SRV1/270-314-------LHPIPNQGQFD-K......KGFGNF-----
Q9VPY4_DROME/935-979-------TQIIEADGRSN-Y......VGLGNK-----
YG0G_SCHPO/112-160-------RAPVRAFRVKN-D.....TIGLGTK-----
RBM6_HUMAN/1051-1095-------ASSEEAEGRMR-G......PSVGAS-----
MTR1_DROME/25-69-------LEPIIAVQQDG-R......RGFGLK-----
O65245_ARATH/52-95-------TEPIKSGIRDR-R......LGLGKQ-----
Q9TYS1_CAEEL/637-681-------LEPLMLDVKSD-R......KGLIAE-----
SUGP1_HUMAN/562-607-------KNPVNKGTTTV-D.....GAGFGID-----
Q9SH49_ARATH/15-59-------KGYVRVTNKQD-T......SGVGLD-----
Q22178_CAEEL/73-120-------TEPIGVDIKAN-R......KGLGHE-----
GPTC1_CAEEL/145-194-------GESSEAQFDRE-Q......ASKVAP-----
GPAN1_MOUSE/271-315-------ANPIPTILKRD-Q......EGLGYR-----
RBM5_HUMAN/743-787-------TAPIEAQVRLK-G......AGLGAK-----
PXR1_YEAST/25-70-------TSHIKVSIKDD-N......VGLGAK-----
DR111_ARATH/214-258-------TTPLMAKKTDR-R......AGVIVN-----
O94028_CANAX/83-127-------INPIETKLRPK-G......LGVGAV-----
YKR3_SCHPO/115-159-------AEPVQSKLRPE-R......VGLGAV-----
VPK4_HUMAN/111-155-------KIPFEAKINQK-R......EGIGYP-----
Q20966_CAEEL/209-254-------STALSIEKTGV-R.....GGNIVAE-----
Q9VI83_DROME/72-116-------TEPVGITIKSG-R......GGLGRE-----
Q61213_MOUSE/783-827-------IEPISPNGNQD-R......QGLGFP-----
YDMD_SCHPO/490-534-------KEAIQPTMYLP-G......VGLGNK-----
Q9SF87_ARATH/635-679-------AQPIEAVQRPK-S......LGLGLD-----
C3H22_ARATH/300-344-------LNPILVKVLPA-K......RSLDYA-----
Q18418_CAEEL/248-292-------VHAIQARICKK-N......ASLDEV-----
Q9VNC5_DROME/230-275-------VDPVNKAPQRD-G.....NQGLGVS-----
GPAN1_CAEEL/263-307-------RFPIRTILKRN-R......AGLGAE-----
O01886_CAEEL/244-294-------VVPVAVYVEED-GQSSKEKTGFGYR-----
VPRT_SMRVH/275-319-------TQPITITPKKD-K......TGLGFH-----
SQS1_YEAST/720-765-------SEPIFAKIKKN-R......SGLRHS-----
Q9SF87_ARATH/736-780-------VNPLVAVRRPR-A......RGIGAE-----
Q22705_CAEEL/26-70-------ADSVKLKANTS-G......RGLGAD-----
TFP11_HUMAN/149-193-------INPIEAKQRKG-K......GAVGAY-----
Q9SHG6_ARATH/200-243-------VAPIEAQLRPK-N......MGMGYN-----
SPF45_MOUSE/235-279-------STALSVEKTSK-R......GGKIIV-----
YAB4_SCHPO/252-301-------INPLHVEISGF-VTE.TKHSKINDK-----
GPTC1_DROME/153-201-------ATARNSKEQYL-M......EHYGAE-----
ZGPAT_DROME/312-356-------VTPVSAQILPQ-G......RSLDAC-----
Q9XWG6_CAEEL/433-477-------VEPVATEVKNN-R......KGLGAN-----
NKRF_HUMAN/551-594-------REPISVKEQHK-R......EGLGLD-----
TFP11_DROME/167-211-------SHPVQAHVRKG-R......GAIGAY-----
Q9VHB0_DROME/705-749-------LQPLLLDVKLD-K......RGLVSR-----
GPAN1_DROME/240-284-------LYPVKTVLRKQ-R......TGLGIE-----
P89941_9BETR/85-129-------RDLAQPKGDFK-RQ....DTGFSWG-----
O59861_LENED/98-141-------RRIQRGDPSPW-.......VKIEEG-----

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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