Sequence alignment for CL0466

PF13180

B5GKK1_9ACTO/268-357----------------------------------------------------------PVIGATVSL-EEN.........
Q7VJB0_HELHP/178-253----------------------------------------------------------GDLGIRFEN-SKA.........
C3XFI7_9HELI/161-241----------------------------------------------------------GDIGVRFDV-ASA.........
A7ZFX4_CAMC1/179-256----------------------------------------------------------GDIGVKFLQ-KED.........
Q0S4Y2_RHOSR/404-487----------------------------------------------------------AVIGIQVPS-QDA.........
A4BWR3_9FLAO/100-182----------------------------------------------------------VGIGVQFRM-ISD.........
D3UIB8_HELM1/171-246----------------------------------------------------------GDIGVRTQG-NI..........
B5JGE0_9BACT/505-583----------------------------------------------------------GWLGASTSG-SGG.........
D1BL26_VEIPT/269-359----------------------------------------------------------PYIGVWAVD-RQTAARN.....
C4FCZ3_9BIFI/468-561----------------------------------------------------------VALGVTVKT-DTVEAD......
C5EYC1_9HELI/179-257----------------------------------------------------------GDIGIRVIQ-NQE.........
A6DE20_9PROT/159-227----------------------------------------------------------GDIGIEVNQ-DMI.........
D3HBS1_STRM6/289-384----------------------------------------------------------PALGIQMVN-LSNINTSDIR.R
B6BJX8_9PROT/225-327----------------------------------------------------------AHMGIGTQK-MENETLRRV...
B1VP64_STRGG/452-541----------------------------------------------------------PVIGATVTM-EEK.........
D2R087_PIRSD/256-349----------------------------------------------------------GFLGVAPSL-LTPDER......
B0R2X2_HALS3/244-350----------------------------------------------------------AYLGVSFTP-VTPTVADA....
B6JPD1_HELP2/170-247----------------------------------------------------------GDIGVRLEE-HHK.........
A5YS57_9EURY/308-391----------------------------------------------------------PGIGITHVV-NET.........
O34248_WOLSU/167-244----------------------------------------------------------GDLLIRFEK-NRR.........
B9CXW4_WOLRE/332-409----------------------------------------------------------GDVGAVFEE-RDG.........
D4FIA0_STAEP/304-394----------------------------------------------------------PSIGIGLIN-LSDIPENYR...
E7FRR7_9LACO/328-425----------------------------------------------------------PALGISLVD-LDYVSEADRSQT
A2RH30_STRPG/301-396----------------------------------------------------------PALGISMVN-LNDLSTNALS.Q
A6C000_9PLAN/277-369----------------------------------------------------------AYLGVQLDP-EFSIATAG....
Q30TR4_SULDN/163-240----------------------------------------------------------GDIGIRVKD-ENS.........
C5EVE7_9FIRM/145-228----------------------------------------------------------SGIGAMISQ-NRT.........
B4V7R0_9ACTO/417-506----------------------------------------------------------PVISVSVDI-QSK.........
C9A6A9_ENTCA/295-392----------------------------------------------------------PALGIQTID-LGSITSQQQEQI
D1XW98_9BACT/96-178----------------------------------------------------------AGIGALIRY-DMV.........
A0AKF7_LISW6/118-196----------------------------------------------------------KAAGQEVKV-TYD.........
A0RM44_CAMFF/175-252----------------------------------------------------------GDIGVTFSD-DNG.........
B6BLX6_9PROT/163-240----------------------------------------------------------GDIGIRVDD-IKK.........
C9ZC44_STRSW/506-595----------------------------------------------------------PVIGASVSL-EEG.........
B1XQ68_SYNP2/485-563----------------------------------------------------------PYLGLTVTD-QNN.........
A9B2Z4_HERA2/473-551----------------------------------------------------------PQLGIRSKA-VDG.........
A6C5H9_9PLAN/245-325----------------------------------------------------------AALGATVTT-GFD.........
Q315Q4_DESDG/369-449----------------------------------------------------------SRMGFTLVM-AEG.........
D5SYB3_PLAL2/269-351----------------------------------------------------------GLMGISFTG-NDL.........
C3XM71_9HELI/174-251----------------------------------------------------------GDIGVRVVE-NAS.........
C0D033_9CLOT/153-236----------------------------------------------------------SGIGAMLSQ-NRN.........
Q1D977_MYXXD/477-552----------------------------------------------------------GWLGVTTRG-SGT.........
A7VHN2_9CLOT/119-202----------------------------------------------------------AGIGVVVRQ-DEE.........
A5Z6X7_9FIRM/108-190----------------------------------------------------------SGIGALVSQ-NAE.........
A3YT34_CAMJU/170-244----------------------------------------------------------GDIGVDFVV-REN.........
C2LWC8_STAHO/306-396----------------------------------------------------------PSIGIGLLN-LSDIPDSYK...
C8X5D5_DESRD/676-755----------------------------------------------------------PVLGLQVRS-QDG.........
B2IZX7_NOSP7/201-295----------------------------------------------------------GYLGVGMQP-VRLPKNLKT...
B5HUE3_9ACTO/403-492----------------------------------------------------------AKIGASVSL-EDS.........
D2QHW4_SPILD/97-182----------------------------------------------------------NGIGALIGQ-RQ..........
B6W6V2_9FIRM/283-372----------------------------------------------------------GITGINLDL-LLQSNNID....
A2TY74_9FLAO/100-182----------------------------------------------------------VGIGVQFRM-IKD.........

PF00595

DVL1_MOUSE/251-336TVTLNME..RH-----------------------------------------------HFLGISIVG-QSN---DR....
ZO1_MOUSE/23-107TVTLHRA..PG-----------------------------------------------FGFGIAISG-GRD---NPHF..
ZO1_MOUSE/186-261KVTLVKS.RKN-----------------------------------------------EEYGLRLAS-...---......
ZO1_MOUSE/423-501KLVKFR...KG-----------------------------------------------DSVGLRLAG-GND---V.....
AFAD_HUMAN/1009-1090TVTLKK....Q-----------------------------------------------NGMGLSIVA-AKG---AGQ...
PTN3_HUMAN/510-595LIRITPD..ED-----------------------------------------------GKFGFNLKG-GVD---QK....
SP4B_BACSU/103-184DLKVIP...GG-----------------------------------------------QSIGVKLHS-VGV---LV....
CTPA_SYNP2/102-182SLKVSTS.GEL-----------------------------------------------SGVGLQINV-NPE---V.....
PDLI1_RAT/5-82QIVLQ....GP-----------------------------------------------GPWGFRLVG-GKD---FE....
APBA1_HUMAN/656-740DVFIEKQ..KG-----------------------------------------------EILGVVIVE-SGW---GS....
APBA2_MOUSE/569-653ELQLEKH..KG-----------------------------------------------EILGVVVVE-SGW---GS....
APBA2_MOUSE/660-733TVLIKRP.DLK-----------------------------------------------YQLGFSVQ.-...---......
ZO1_HUMAN/23-107TVTLHRA..PG-----------------------------------------------FGFGIAISG-GRD---NPHF..
ZO1_HUMAN/186-261KVTLVKS.RKN-----------------------------------------------EEYGLRLAS-...---......
ZO1_HUMAN/423-501KLVKFR...KG-----------------------------------------------DSVGLRLAG-GND---V.....
DLG1_DROME/216-300DIQLER...GN-----------------------------------------------SGLGFSIAG-GTD---NPHI..
DLG1_DROME/330-418EIDLVK...GG-----------------------------------------------KGLGFSIAG-GIG---NQHI..
DLG1_DROME/506-584TITIQK...GP-----------------------------------------------QGLGFNIVG-GED---G.....
PDLI4_HUMAN/4-81SVTLR....GP-----------------------------------------------SPWGFRLVG-GRD---FS....
DSH_DROME/252-337TVSINME..AV-----------------------------------------------NFLGISIVG-QSN---RG....
DVL1L_HUMAN/251-336TVTLNME..RH-----------------------------------------------HFLGICIVG-QSN---DR....
DVL2_XENLA/254-339TVTLNME..KY-----------------------------------------------NFLGISIVG-QSN---ER....
EM55_TAKRU/73-151EVAFEKN..QS-----------------------------------------------EPLGVTLKL-NDK---Q.....
EM55_HUMAN/71-149LIQFEKV..TE-----------------------------------------------EPMGITLKL-NEK---Q.....
GSPC_KLEPN/190-270ELRAQPQ.NIL-----------------------------------------------HYLNISPVM-VND---K.....
DEGQ_ECOLI/257-346QLIDFGE.IKR-----------------------------------------------GLLGIKGTE-MSA---DIAKAF
DEGQ_ECOLI/365-444SASAEMI..TP-----------------------------------------------ALEGATLSD-GQL---KD....
DEGS_ECOLI/248-336LIRDGRV..IR-----------------------------------------------GYIGIGGRE-IAP---LHAQGG
DEGS_HAEIN/242-322KIMRDGR.VIR-----------------------------------------------GYFGVQSDI-SSS---SE....
HTOA_HAEIN/268-358QQILEFGQVRR-----------------------------------------------GLLGIKGGE-LNA---DLAKAF
HTOA_HAEIN/377-455QLSSKTE..LP-----------------------------------------------ALDGATLKD-YDA---KG....
DEGPL_BARHE/289-378QQLIEKGLVQR-----------------------------------------------GWLGVQIQP-VTK---EISDSI
DEGP_ECOLI/279-368QMVEYGQ.VKR-----------------------------------------------GELGIMGTE-LNS---ELAKAM
DEGP_SALTY/280-369QMVEYGQ.VKR-----------------------------------------------GELGIMGTE-LNS---ELAKAM
DEGP_SALTY/386-464QSQVDS...ST-----------------------------------------------IFSGIEGAE-MSN---KG....
LIMK1_HUMAN/165-255LVSIPAS..SH-----------------------------------------------GKRGLSVSI-DPP---HGPPGC
LIMK1_MOUSE/165-255LVSIPAS..AH-----------------------------------------------GKRGLSVSI-DPP---HGPPGC
LIMK1_RAT/165-255LVSIPAS..AH-----------------------------------------------GKRGLSVSI-DPP---HGPPGC
LIMK2_CHICK/152-236LISMPAA..TD-----------------------------------------------GKRGFSVSV-EGG---CSS...
LIMK2_HUMAN/152-236LISMPAT..TE-----------------------------------------------GRRGFSVSV-ESA---CSN...
LIMK2_RAT/152-236LISMPAT..TE-----------------------------------------------CRRGFSVSV-ESA---SSN...
LIN2_CAEEL/546-624LVQFQKD..TQ-----------------------------------------------EPMGITLKV-NED---G.....
NOS1_HUMAN/17-96SVRLFKR..KV-----------------------------------------------GGLGFLVKE-RVS---K.....
NOS1_RAT/17-96SVRLFKR..KV-----------------------------------------------GGLGFLVKE-RVS---K.....
PRC_HAEIN/244-328SFNESIN.LSL-----------------------------------------------EGIGTTLQS-EDD---......
DLG4_RAT/65-149EITLER...GN-----------------------------------------------SGLGFSIAG-GTD---NPHI..
DLG4_RAT/160-244EIKLIK...GP-----------------------------------------------KGLGFSIAG-GVG---NQHI..
DLG4_RAT/313-391RIVIHR...GS-----------------------------------------------TGLGFNIVG-GED---G.....
PTN4_HUMAN/516-602VLIRMKP.DEN-----------------------------------------------GRFGFNVKG-GYD---QK....
PTP1_CAEEL/616-703VTIKMRP.DRH-----------------------------------------------GRFGFNVKG-GAD---QN....
SIPA1_MOUSE/682-754ELALPRD..GQ-----------------------------------------------GRLGFEVDA-...---......
APBA1_HUMAN/746-820TTVLIRRPDLR-----------------------------------------------YQLGFSVQ.-...---......
RSEP_ECOLI/203-277EPDKED...PV-----------------------------------------------SSLGIRPRG-PQI---......
Y918_HAEIN/202-273DPEKES...AF-----------------------------------------------EALGIMPMR-PKI---......
PSMD9_YEAST/99-191RSHVLL...NQ-----------------------------------------------HFDNMNVKS-NQD---ARRNND
NM111_YEAST/290-375QWLLKPY.DEC-----------------------------------------------RRLGLTSER-ESE---ARAK..
YQI7_CAEEL/25-114EVIDAHG.QVT-----------------------------------------------IRVGFKIGG-GID---QDPTKA
PRC_ECOLI/238-320NTEMSL...SL-----------------------------------------------EGIGAVLQM-DDD---......

PF14685

D0KPY8_SULS9/713-798----------------------------------------------------------GGLGAEFEY.DES---N..KC.
TRIC_SULTO/556-640----------------------------------------------------------GGLGADYEY.DKE---N..KC.
TRI_THEVO/723-810----------------------------------------------------------GRIACDFKY.S..---N..GE.
TRI_THEAC/763-849----------------------------------------------------------GRIACDFKL.D..---G..DH.
Q4J6J4_SULAC/709-795----------------------------------------------------------GGLGAEFNY.D..---EQREC.
D6TD68_9CHLR/771-861----------------------------------------------------------GFLGVDWSY.DAE---K..QR.
A7NMU6_ROSCS/788-877----------------------------------------------------------GKLGADLRY.DAE---T..DS.
A5US97_ROSS1/783-872----------------------------------------------------------GRLGADLRY.DAE---T..DS.
D3Q8U1_STANL/765-853----------------------------------------------------------GYLGADFTV.D..---T.DGA.
Q8ZXG0_PYRAE/721-807----------------------------------------------------------GGLGAEFKW.D..---G..KC.
B1KFH4_SHEWM/759-846----------------------------------------------------------GLLGADFEV.K..---N..GL.
A8UNS9_9FLAO/762-851----------------------------------------------------------GLLGCDIEL.V..---N..GN.
E8WXR8_ACISM/803-890----------------------------------------------------------GLLGADYTI.V..---N..NQ.
D2AWH2_STRRD/739-825----------------------------------------------------------GKLGVDWSF.E..---D..GL.
E6PEL4_9ZZZZ/754-843----------------------------------------------------------GFLGADYRW.D..---G..ERN
F2L4Y9_THEU7/718-804----------------------------------------------------------GGLGAEFAW.D..---G..SC.
Q020G3_SOLUE/804-893----------------------------------------------------------GLLGADYEI.V..---N..GR.
A3UJ31_9RHOB/772-861----------------------------------------------------------GLLGADFTL.E..---G..GR.
E1ICY4_9CHLR/759-849----------------------------------------------------------GFLGADLAY.DPE---T..DS.
C2G1Q2_9SPHI/768-857----------------------------------------------------------GMLGADYKI.T..---D..NR.
A4BZR3_9FLAO/755-842----------------------------------------------------------GLLGADLEK.N..---R..GR.
D9PGC5_9ZZZZ/747-836----------------------------------------------------------GYLGIDWEI.A..---N..ST.
B0VF46_CLOAI/747-837----------------------------------------------------------GKLGIDYRY.NAR---K..KG.
A9BIW8_PETMO/751-841----------------------------------------------------------GYLGADLIL.D..---E..DRK
B3QU45_CHLT3/747-837----------------------------------------------------------GLLGADISY.STE---K..KA.
D9QMJ3_BRESC/796-884----------------------------------------------------------GLLGADYAI.Q..---G..GR.
C6WJJ9_ACTMD/754-843----------------------------------------------------------GLLGADLERGE..---D..GS.
E4NAZ7_KITSK/757-844----------------------------------------------------------GLLGADLVR.D..---G..EV.
D9Y1R2_9ACTO/760-849----------------------------------------------------------GLLGADVSR.H.E---D..GS.
C7Q5E5_CATAD/793-881----------------------------------------------------------GLLGADLAP.D..---E.DGV.
D6B076_9ACTO/767-856----------------------------------------------------------GLLGADLAR.D.E---E..GV.
B4D285_9BACT/824-912----------------------------------------------------------GYLGCDYAL.E..---Q..GA.
D4VA73_BACVU/751-841----------------------------------------------------------GLLGAELSR.D..---K.GGF.
E1WP31_BACF6/758-848----------------------------------------------------------GLLGAEITR.D..---K.SGF.
E4RW77_LEAB4/768-855----------------------------------------------------------GYLGIDWQA.D..---G..NH.
B5G810_9ACTO/757-846----------------------------------------------------------GLLGADISR.H.E---D..GQ.
D0TG11_9BACE/757-847----------------------------------------------------------GLLGAEVSR.D..---K.SGF.
C1N9P1_MICPC/828-915----------------------------------------------------------GRLGCDLVW.D..---A..KMR
D9UTL0_9ACTO/419-505----------------------------------------------------------GLLGADFTC.R..---D..GA.
D2ARY8_STRRD/732-815----------------------------------------------------------GLLGADLSW.N.G---D..GR.
B5GPX5_STRCL/828-913----------------------------------------------------------GMLGADLVR.R..---D..GR.
B5HKU3_9ACTO/746-831----------------------------------------------------------GLLGANFVL.R..---E..GG.
D6B1U4_9ACTO/818-904----------------------------------------------------------GLLGANLVR.V..---G..DQ.
D9WLZ7_9ACTO/795-883----------------------------------------------------------GLLGADFTP.T.E---D..GG.
D5ZWH5_9ACTO/838-925----------------------------------------------------------GLLGANLVP.R..---E..EG.
D6K3M6_9ACTO/906-993----------------------------------------------------------GLLGADLVR.R..---D..AG.
E4NBJ1_KITSK/740-825----------------------------------------------------------GLLGANAHR.A.P---D..GR.

PF04495

Q2LYW0_DROPS/69-205LTVYSSKTQTVRELTL.TP...............STSWGGQ.................GLLGVSIRFCSFE---------
Q0U7P0_PHANO/83-216LGVFSAKGQKIREVYISVP...............STN.....................PTLGISLQWSPLA---------
Q6BX19_DEBHA/130-306LDVWSAKGGIVRQVILPLDKFEPSSKDDADESELSLFNDSF.................SQVGLTLQSQHLN---------
A5DBW3_PICGU/154-329LDVWSAKGGIIRQVRLPLNKPDELKD.ETSVDSSKLFYGLF.................AEIGVVLSSQHLN---------
GORS2_MOUSE/69-205MLIYSSKTLELREASV.TP...............SNLWGGQ.................GLLGVSIRFCSFD---------
Q5CNE5_CRYHO/133-257LRVYQFLSYDERI.............................................SGLGIGVHWEEIS---------
Q5F353_CHICK/69-205MLVYSSKTLELRETSV.TP...............SNMWGGQ.................GLLGVSIRFCSFD---------
Q5U3V8_DANRE/70-206MEVYSTKTMRMRELEV.VP...............SNMWGGQ.................GLLGASVRFCSFQ---------
Q4SNY6_TETNG/69-235MLVYSSKTLELREATV.TP...............SNLWGGQ.................GLLGVSIRFCSFE---------
Q0IEU2_AEDAE/69-205MTVFSSKTQNIRVVNI.MP...............STTWGGQ.................GLLGVSIRFCSFE---------
A6ZZA4_YEAS7/141-282ISIISKESDDLDDVSLNHDER...........RPSSGEAHQ................FQALGFKVQWTPLI---------
Q5KDT5_CRYNJ/68-205LRVYNTKSQRVREA....................SKASGDPNA.............KPSLLGLSLRVCNPA---------
Q6PC76_DANRE/69-205MQVYSSKTLELREATV.TP...............SNMWGGQ.................GLLGVSIRFCSFE---------
YAT2_SCHPO/80-213LEVFSLKGQITRKVNIKIN...............SDE......................KIGMVLQWASIA---------
GORS1_MOUSE/68-204LEVFNMKTMKVREVEV.VP...............SNMWGGQ.................GLLGASVRFCSFR---------
Q4UCI6_THEAN/70-205LTVYNARKKNIRDVYI.VP................QKWDGI.................GLLGLTLKFGLFS---------
Q54C46_DICDI/73-210LIVYNIKSDTTREVSI.TP...............STTWGGQ.................GLAGISIRYCSWE---------
Q2UN33_ASPOR/80-214FEIWSAKGQKTHTASIPIS...............PSN.....................PTLGVALQLAPLS---------
A7ARE9_BABBO/70-205LNVYNARQKSLRLIKI.TP................RKWDGV.................GLLGLSVRFAEFT---------
E9BPI9_LEIDB/103-265FTTFNLYSRTYRDVYC.VP...............SDEWGGG.................GLLGCSIEWTRAD---------
Q4Q3U9_LEIMA/103-265FTTFNLYSRTYRDVYC.VP...............SDEWGGG.................GLLGCSIEWTRAD---------
Q7QJA4_ANOGA/69-205MTVYSSKTQNIRLVDI.TP...............SSTWGGQ.................GLLGVSIRFCSFE---------
A1DMR0_NEOFI/97-231FEIWSAKGQKTHSVSIPVP...............PSN.....................PTLGLALQLAPLS---------
Q6GLD6_XENTR/71-207LEVYNTKSMKVREVEV.TP...............SNMWGGQ.................GLLGASVRFCSFQ---------
Q28J72_XENTR/69-205MVVYSSKTLELRETSV.TP...............SNMWGGQ.................GLLGVSIRFCSFE---------
Q5CZ04_CRYPI/133-257LRVYQFLSYDERI.............................................SGLGIGVHWEEIS---------
Q5ZK65_CHICK/69-205LEVYNIKTMKIREVEV.VP...............SNMWGGQ.................GLLGASVRFCSFQ---------
Q22G20_TETTS/89-227MVIYDILQRKIRIVKV.VP...............NKDWSNQ................QNLLGVMLRLENYL---------
Q2YDP4_BOVIN/69-205LEVFNMKTMKVREVEV.VP...............SNMWGGQ.................GLLGASVRFCSFR---------
Q386P4_TRYB2/73-244LTVYNLYIHNYRDVHC.VA...............SSTWGGG.................GLLGCSVEWCQAE---------
Q4N0A2_THEPA/102-237LSIYNARKKNIRDVYI.VP................QKWDGI.................GLLGLTLKFGLFN---------
Q4PFN7_USTMA/83-237LNVWNSKRQQLRQVSL.VP...............SREWSSQPSTSSINGTSSRATSQPSLLGLSLRLCNPS---------
Q2HFQ7_CHAGB/78-211LGLWSAKGQRTRALHVPVP...............ANT.....................ASLGLALQWTPVA---------
Q0CI81_ASPTN/81-215FEIWSAKGQKTHRVSIPVS...............PDN.....................PTLGLALQLAPLS---------
A5DW42_LODEL/191-326LESF.........................................................GLTVESQHLS---------
A7EGH4_SCLS1/79-212LGLWSAKGQRTRTIHIPVP...............SDT.....................PSLGLTLQWTSLS---------
A6RJ89_BOTFB/62-195ANLFAQEGQRTRTIHIPVP...............SDT.....................PSLGLTLQWTSLS---------

PF12812

B8MUN1_TALSN/264-341AITPDRFV--------------------------------------------------SVAGATFHDLSYQ------QAR
NM111_PICST/379-456SITPDRYV--------------------------------------------------DVGGASFNNLSYQ------VAR
NM111_PICGU/388-465SITPSRYV--------------------------------------------------DIAGASFNDLSYQ------VAR
NM111_LODEL/379-456AITPDRFV--------------------------------------------------HVAGASFNNLSYQ------VAR
B9W6Q0_CANDC/376-453SITPNRFV--------------------------------------------------VVAGASFNDLSYQ------IAR
C5MEA8_CANTT/370-447DITPNRFV--------------------------------------------------SVAGATFNDMSYQ------IAR
NM111_YEAS7/392-469AITPHRYV--------------------------------------------------EVCGATFHELSYQ------MAR
NM111_CANGA/374-451AITPSKYV--------------------------------------------------EVCGATFNELSYQ------MAR
NM111_ASHGO/372-449AITPSRYV--------------------------------------------------EVCGATFNELSYQ------MAR
NM111_KLULA/388-465IITPSRYV--------------------------------------------------EVCGANFHELSYQ------MAR
C4R214_PICPG/366-443AITPARYL--------------------------------------------------EVCGASFNDLSYQ------MAR
NM111_YARLI/360-439SITPDRYV--------------------------------------------------EVCGASFQDLSYQ------LAR
B6JWG1_SCHJY/372-448AIAPDRYV--------------------------------------------------EVCGATFHNLSYQ------LAR
B2RIG1_PORG3/398-471VITGESTG--------------------------------------------------NVLGASFKDLSAE------QMR
A6SSR9_BOTFB/12-90DLETDRAI--------------------------------------------------SFCGAILHR.PHH------AVR
B2WNT3_PYRTR/845-923DLETDRLV--------------------------------------------------SFCGATFHR.PHQ------AVR
C4Y709_CLAL4/134-212SMNTSRVV--------------------------------------------------FWCGALLQE.PHQ------SVR
NM111_KLULA/861-937ETT..RIV--------------------------------------------------VFAGCVLQA.PHH------AVR
Q6CHS4_YARLI/371-442ALSCTEFV--------------------------------------------------KFGGMTFHNMTYQ------LVR
B6QC43_PENMQ/337-413AIVPTRIL--------------------------------------------------NDSGASFHNVPYR------TAV
B9H391_POPTR/179-254LITPDCFL--------------------------------------------------EVSGAVIHRLSYQ------QAR
B8AHP7_ORYSI/375-450SITPNHFL--------------------------------------------------EVSGAVIHPLSYQ------QAR
A9RQ61_PHYPA/347-422SITPNMFL--------------------------------------------------EVSGGVLHALSYQ------QAR
A8JH35_CHLRE/368-444TVTPNCFL--------------------------------------------------ELAGGAVHALSYQ------QAR
C1EGI7_MICSR/349-424DVTPSRFL--------------------------------------------------EVCGGVVHALSYQ------QAR
C1N456_MICPC/359-434AITPSRML--------------------------------------------------EIAGGVVNALSYQ------QAR
B6K3R7_SCHJY/399-475SVTPSRFL--------------------------------------------------EVGGTIFHDLSYQ------LAR
YH05_SCHPO/393-469NVTPSRFL--------------------------------------------------EVGGAVLHDLSYQ------LAR
B8FNF0_DESAA/337-420KIT..RFA--------------------------------------------------TFAGGTFHPLTPE------IRL
NM111_MAGO7/393-469SITPDRFV--------------------------------------------------SVAGGSFHSLSYQ------QAR
B2ASP9_PODAN/396-472KITPDRFV--------------------------------------------------SVAGGSFHELSYQ------QAR
B2WNT3_PYRTR/372-451AITPDKFV--------------------------------------------------SVAGASFHDLSYQ------QAR
C0NX23_AJECG/394-470EITPARYV--------------------------------------------------TVAGATFHDLSYQ------QAR
B6HPJ1_PENCW/491-567DITPDRFV--------------------------------------------------TVAGASFHDLSYQ------QSR

PF13180

B5GKK1_9ACTO/268-357.......MDGATISDQGAGSDPAVT-PG--GPAAK------GG.--LKS..............GDTITQL--D-------
Q7VJB0_HELHP/178-253.........I.............VK-SI--DPFVP------QNP--FKP..............QDKILSI--N-------
C3XFI7_9HELI/161-241.........ENATFV........VQ-FS--DPFFP------SNP--FKR..............GDTLISI--N-------
A7ZFX4_CAMC1/179-256.........KFF...........VG-LV--DPLGR------GKM--MMV..............DDELVTI--N-------
Q0S4Y2_RHOSR/404-487.......ANGATVVE........VT-AG--SPAEK------AG.--IPK..............GSVITKV--D-------
A4BWR3_9FLAO/100-182.........SITVIQ........PI-KG--GPSIR------AG.--IKA..............GDRILMA--N-------
D3UIB8_HELM1/171-246.......................VL-QI--DPFFP------NNP--FLP..............DDKILKI--Q-------
B5JGE0_9BACT/505-583.........IVKVTS........VP-SD--TPAAA------AG.--LCV..............DDEIIAL--D-------
D1BL26_VEIPT/269-359..NVSYEGEGLLIVQ........LD-ST--GPAAQ------AG.--LVE..............GDTIAQI--D-------
C4FCZ3_9BIFI/468-561....GVTRAGARITSSST..GNAVV-KG--GPADK------AG.--LKS..............GDTIVAF--D-------
C5EYC1_9HELI/179-257........DRVE...........VS-LI--DPFFE------NNP--FKY..............GDIIMMV--N-------
A6DE20_9PROT/159-227.......................VK-YI--DPFYV------KG.--IKL..............GDKIISI--N-------
D3HBS1_STRM6/289-384LNIPSNVTSGVVVRS........VQ-SN--MPANG------H..--LEK..............YDVITKV--D-------
B6BJX8_9PROT/225-327.NKMDDNTTGVLIID........VA-QK--SAAFD------K..--IKP..............GDVLLSI--D-------
B1VP64_STRGG/452-541.......TGGAAISAEGAGGTPAVT-PN--GPAAK------AG.--LKA..............GDVITKF--N-------
D2R087_PIRSD/256-349....RAGKLGARIAD........VV-PA--TPAAK------AG.--LAM..............GDIVTHV--G-------
B0R2X2_HALS3/244-350..NGLTESRGLLVMS........VD-PS--GPSAG------RL.--VGSDATTIVDGGAVRVGGDIVLAV--N-------
B6JPD1_HELP2/170-247.........RLV...........VA-QF--DPFFP------KNP--FLK..............NDEILAI--N-------
A5YS57_9EURY/308-391........NAIEVLTP......GNG-QI--TYNNQ------QM.--LLV..............GDIITHV--D-------
O34248_WOLSU/167-244.........EPV...........VA-LI--DPFIE------ENL--FRL..............GDRVLSL--E-------
B9CXW4_WOLRE/332-409.........KFY...........TK-SV--DPLGR------GAA--LMT..............GDEVLSI--N-------
D4FIA0_STAEP/304-394KELHTHKDKGVYVAK........VD-SE--NA...------...--IKK..............GDIITGI--D-------
E7FRR7_9LACO/328-425LNLPSKVTSGVVVMK........VN-SS--SPLKK------TD.--ISK..............YDVIVSL--G-------
A2RH30_STRPG/301-396INIPTSVTGGIVVAE........VK-EG--MPASG------K..--LAQ..............YDVITEI--D-------
A6C000_9PLAN/277-369.RLKMDRVRGARVVK........VI-SN--TPASR------AN.--LKY..............DDIILSF--G-------
Q30TR4_SULDN/163-240.........VVI...........VK-ES--NPFVE------SNQ--LKV..............GDVILEF--D-------
C5EVE7_9FIRM/145-228.......TGLCTIVK........VF-EG--SPALE------AG.--MQP..............GDIIYKV--G-------
B4V7R0_9ACTO/417-506.......AEGAKISDSGASAGDLVD-PN--GPAGK------AG.--LKP..............GDLITQF--G-------
C9A6A9_ENTCA/295-392LKVPSSVTSGVVIYS........VN-NA--TPAEQ------AG.--LQQ..............YDVITKI--D-------
D1XW98_9BACT/96-178.......LKRVTIDE........PY-EK--QPAAE------AG.--LKK..............GDILLAI--D-------
A0AKF7_LISW6/118-196.........GVYVLS........VK-ED--VPAAD------V..--LHA..............GDLITEI--D-------
A0RM44_CAMFF/175-252.........TIT...........VK-SA--NPFGA------GKE--LLT..............GDTIVSV--N-------
B6BLX6_9PROT/163-240.........SIT...........IT-RV--NPFIK------DNP--FQE..............GDTIVDF--A-------
C9ZC44_STRSW/506-595.......TGGAKITNSGGGGSESIT-AN--GPADK------AG.--LKP..............GDVITKL--D-------
B1XQ68_SYNP2/485-563.........RTLVQT........VN-VD--SPAHQ------AG.--IDP..............EDELLAI--T-------
A9B2Z4_HERA2/473-551.........RVQITH........VL-DG--GDADR------AG.--LAA..............GDELIAL--D-------
A6C5H9_9PLAN/245-325........SNINVAE........IL-EE--SDAYR------KG.--LRL..............GDEIVSF--A-------
Q315Q4_DESDG/369-449.........RVTVQD........VA-ED--SPARR------AG.--FRA..............GDVLRSA--D-------
D5SYB3_PLAL2/269-351.......SGDAPVVE.......RVR-FQ--SPAAA------AG.--ILV..............NDVIVAA--D-------
C3XM71_9HELI/174-251.........GVE...........VS-VV--DPFFK------KNP--FKY..............GDVITSI--N-------
C0D033_9CLOT/153-236.......TGLCTIVR........VF-EN--SPAFE------AG.--MKP..............GDILYKV--E-------
Q1D977_MYXXD/477-552............VAV........VM-DG--SPAQD------AG.--LYV..............EDDLVAL--N-------
A7VHN2_9CLOT/119-202.......TGYAIAVS........IT-ED--SPASE------VD.--IKP..............DDLICKI--D-------
A5Z6X7_9FIRM/108-190.......TGIITVVK........AF-AD--APAAK------AG.--VKN..............GDIIYKV--K-------
A3YT34_CAMJU/170-244.......................KI-YV--NNVRK------NPQ--FLI..............NDQVISV--D-------
C2LWC8_STAHO/306-396KELKTDRDTGVYIAK........VS-HS--SE...------...--LKV..............GDIITKV--D-------
C8X5D5_DESRD/676-755.........GVVVQN........IH-DG--TPAVA------SG.--LRT..............GDHILRF--Q-------
B2IZX7_NOSP7/201-295.ALNLTSATGVIVVN........VE-SS--GPADN------AG.--VLL..............GDILVTF--D-------
B5HUE3_9ACTO/403-492.......SGGAKITTEGAGGSAPVE-SG--GPAAK------AG.--LKP..............GDVITKL--D-------
D2QHW4_SPILD/97-182.........GKSIVL.......MVY-EG--TPAEK------SG.--LQI..............GDEVLKV--D-------
B6W6V2_9FIRM/283-372.PKTVGSEDGVY...........VQ-SV--SDDAR------NY.--FRK..............GDIIVGI--D-------
A2TY74_9FLAO/100-182.........SITVIQ........PI-KG--GPSIK------AG.--IKA..............GDRILMA--N-------

PF00595

DVL1_MOUSE/251-336......GDGGIYIGS--------IM-KG..GAVAA------DGR--IEP--------------GDMLLQV..N-------
ZO1_MOUSE/23-107....QSGETSIVISD--------VL-KG..GPAEG------Q..--LQE--------------NDRVAMV..N-------
ZO1_MOUSE/186-261.........HIFVKE--------IS-QD..SLAAR------DGN--IQE--------------GDVVLKI..N-------
ZO1_MOUSE/423-501.........GIFVAG--------VL-ED..SPAAK------EG.--LEE--------------GDQILRV..N-------
AFAD_HUMAN/1009-1090......DKLGIYVKS--------VV-KG..GAADV------DGR--LAA--------------GDQLLSV..D-------
PTN3_HUMAN/510-595........MPLVVSR--------IN-PE.SPADTC------IPK--LNE--------------GDQIVLI..N-------
SP4B_BACSU/103-184........VGFHQIN--------TS-EGKKSPGET------AG.--IEA--------------GDIIIEM..N-------
CTPA_SYNP2/102-182........DVLEVIL--------PL-PG..SPAEA------AG.--IEA--------------KDQILAI..D-------
PDLI1_RAT/5-82........QPLAISR--------VT-PG.SKAAIA------N..--LCI--------------GDLITAI..D-------
APBA1_HUMAN/656-740......ILPTVIIAN--------MM-HG..GPAEK------SGK--LNI--------------GDQIMSI..N-------
APBA2_MOUSE/569-653......ILPTVILAN--------MM-NG..GPAAR------SGK--LSI--------------GDQIMSI..N-------
APBA2_MOUSE/660-733.........NGIICS--------LM-RG..GIAER------GG.--VRV--------------GHRIIEI..N-------
ZO1_HUMAN/23-107....QSGETSIVISD--------VL-KG..GPAEG------Q..--LQE--------------NDRVAMV..N-------
ZO1_HUMAN/186-261.........HIFVKE--------IS-QD..SLAAR------DGN--IQE--------------GDVVLKI..N-------
ZO1_HUMAN/423-501.........GIFVAG--------VL-ED.SPAAKE------G..--LEE--------------GDQILRV..N-------
DLG1_DROME/216-300.....GTDTSIYITK--------LI-SG..GAAAA------DGR--LSI--------------NDIIVSV..N-------
DLG1_DROME/330-418.....PGDNGIYVTK--------LM-DG..GAAQV------DGR--LSI--------------GDKLIAVRTN-------
DLG1_DROME/506-584........QGIYVSF--------IL-AG..GPADL------GSE--LKR--------------GDQLLSV..N-------
PDLI4_HUMAN/4-81........APLTISR--------VH-AG.SKAALA------A..--LCP--------------GDLIQAI..N-------
DSH_DROME/252-337......GDGGIYVGS--------IM-KG..GAVAL------DGR--IEP--------------GDMILQV..N-------
DVL1L_HUMAN/251-336......GDGGIYIGS--------IM-KG..GAVAA------DGR--IEP--------------GDMLLQV..N-------
DVL2_XENLA/254-339......GDGGIYIGS--------IM-KG..GAVAA------DGR--IEP--------------GDMLLQV..N-------
EM55_TAKRU/73-151.........RCSVAR--------IL-HG..GMIHR------QGS--LHE--------------GDEIAEI..N-------
EM55_HUMAN/71-149.........SCTVAR--------IL-HG..GMIHR------QGS--LHV--------------GDEILEI..N-------
GSPC_KLEPN/190-270........LSGYRLN--------PG-KD..PALFR------QSG--LRE--------------NDLAIAL..N-------
DEGQ_ECOLI/257-346...NLDVQRGAFVSE--------VL-PG.SGSAKA------G..--VKA--------------GDIITSL..N-------
DEGQ_ECOLI/365-444......GGKGIKIDE--------VV-KG.SPAAQA------G..--LQK--------------DDVIIGV..N-------
DEGS_ECOLI/248-336...GIDQLQGIVVNE--------VS-PD.GPAANA------G..--IQV--------------NDLIISV..D-------
DEGS_HAEIN/242-322........EGIVITD--------VS-PN.SPAAKS------G..--IQV--------------GDVILKL..N-------
HTOA_HAEIN/268-358...NVSAQQGAFVSE--------VL-PK..SAAEK------AG.--LKA--------------GDIITAM..N-------
HTOA_HAEIN/377-455.......VKGIEITK--------IQ-PN.SLAAQR------G..--LKS--------------GDIIIGI..N-------
DEGPL_BARHE/289-378...GLKEAKGALITD--------PL-KG..PAAKA------G..--IKA--------------GDVIISV..N-------
DEGP_ECOLI/279-368...KVDAQRGAFVSQ--------VL-PN.SSAAKA------G..--IKA--------------GDVITSL..N-------
DEGP_SALTY/280-369...KVDAQRGAFVSQ--------VM-PN.SSAAKA------G..--IKA--------------GDVITSL..N-------
DEGP_SALTY/386-464......QDKGVVVSS--------VK-AN.SPAAQI------G..--LKK--------------GDVIIGA..N-------
LIMK1_HUMAN/165-255...GTEHSHTVRVQG--------VD-PG.CMSPDV------KNS--IHV--------------GDRILEI..N-------
LIMK1_MOUSE/165-255...GTEHSHTVRVQG--------VD-PG.CMSPDV------KNS--IHV--------------GDRILEI..N-------
LIMK1_RAT/165-255...GTEHSHTVRVQG--------VD-PG.CMSPDV------KNS--IHI--------------GDRILEI..N-------
LIMK2_CHICK/152-236......YATGVQVKE--------VN-RM.HISPDV------RNA--IHP--------------ADRILEI..N-------
LIMK2_HUMAN/152-236......YATTVQVKE--------VN-RM.HISPNN------RNA--IHP--------------GDRILEI..N-------
LIMK2_RAT/152-236......YATTVQVKE--------VN-RM.HISPNN------RNA--IHP--------------GDRILEI..N-------
LIN2_CAEEL/546-624.........RCFVAR--------IM-HG..GMIHR------QAT--LHV--------------GDEIREI..N-------
NOS1_HUMAN/17-96........PPVIISD--------LI-RG..GAAEQ------SGL--IQA--------------GDIILAV..N-------
NOS1_RAT/17-96........PPVIISD--------LI-RG..GAAEQ------SGL--IQA--------------GDIILAV..N-------
PRC_HAEIN/244-328.........EISIKS--------LV-PG..APAER------SKK--LHP--------------GDKIIGV..G-------
DLG4_RAT/65-149.....GDDPSIFITK--------II-PG..GAAAQ------DGR--LRV--------------NDSILFV..N-------
DLG4_RAT/160-244.....PGDNSIYVTK--------II-EG..GAAHK------DGR--LQI--------------GDKILAV..N-------
DLG4_RAT/313-391........EGIFISF--------IL-AG..GPADL------SGE--LRK--------------GDQILSV..N-------
PTN4_HUMAN/516-602........MPVIVSR--------VA-PG.TPADLC------VPR--LNE--------------GDQVVLI..N-------
PTP1_CAEEL/616-703........YPVIVSR--------VA-PG.SSADKC------QPR--LNE--------------GDQVLFI..D-------
SIPA1_MOUSE/682-754.........EGFITH--------VE-RF..TFAET------TG.--LRP--------------GARLLRV..C-------
APBA1_HUMAN/746-820.........NGIICS--------LM-RG..GIAER------GG.--VRV--------------GHRIIEI..N-------
RSEP_ECOLI/203-277.........EPVLEN--------VQ-PN..SAASK------AG.--LQA--------------GDRIVKV..D-------
Y918_HAEIN/202-273.........EMVLSK--------VV-QN..SPAEK------AG.--LQI--------------GDKILKE..N-------
PSMD9_YEAST/99-191DQAIQYTIPFAFISE--------VV-PG.SPSDKA------D..--IKV--------------DDKLISI..G-------
NM111_YEAST/290-375....FPENIGLLVAE--------TV-LR.EGPGYD------K..--IKE--------------GDTLISI..N-------
YQI7_CAEEL/25-114..PFKYPDSGVYITN--------VE-SG..SPADV------AG.--LRK--------------HDKILQV..N-------
PRC_ECOLI/238-320.........YTVINS--------MV-AG..GPAAK------SKA--ISV--------------GDKIVGV..G-------

PF14685

D0KPY8_SULS9/713-798.YKITKIYVGDSTNE--------NE-RS--PLRDP------GVQ--LNV--------------GDCIKNI--D-------
TRIC_SULTO/556-640.YKIARIYVGDPTNE--------NE-RS--PLRDP------GVQ--LNI--------------GDCIKAV--D-------
TRI_THEVO/723-810.YVISDILYGDPSNE--------NE-KS--PFLLS------TLD--ADI--------------GDAVIEI--D-------
TRI_THEAC/763-849.YVVAKAYAGDYSNE--------GE-KS--PIFEY------GID--P.T--------------GYLIEDI--D-------
Q4J6J4_SULAC/709-795.FKIVKIYSGDPTNE--------GE-RS--PLKDP------GVE--LNE--------------GDCIYSI--D-------
D6TD68_9CHLR/771-861.YLITRIVKGDTANS--------HE-TS--PLTLP------GLE--VAV--------------GDAVLAI--N-------
A7NMU6_ROSCS/788-877.YIVERIVAGDVWNE--------RA-SS--PLARP------GVN--IAP--------------GDRLIAI--G-------
A5US97_ROSS1/783-872.YVVERVIRGDVWDE--------RA-SS--PLAQP------GIN--IVP--------------GDRLIAV--G-------
D3Q8U1_STANL/765-853.HTIAKIYTGDPWKP--------DA-TS--SLLRP------GVD--ARV--------------GDTVVAV--N-------
Q8ZXG0_PYRAE/721-807.WRIAKIFVGDPSYE--------NE-KS--PLLAP------GVD--VRE--------------GDCIISI--A-------
B1KFH4_SHEWM/759-846.YRIKNIYTGEAWNP--------HL-KA--PLAVP------GNK--VSV--------------GDYILEV--D-------
A8UNS9_9FLAO/762-851.FRISKIYNGERWNP--------NL-KA--PLAQP------GIK--VNE--------------GDYLLAI--N-------
E8WXR8_ACISM/803-890.YCIAKLYDGGHWNP--------NM-TG--PLTQP------GLN--VHV--------------GDCITAI--G-------
D2AWH2_STRRD/739-825.YRVARIVNGDRWDP--------EV-TS--PLNRL------GVD--VRP--------------GDVVLAV--N-------
E6PEL4_9ZZZZ/754-843GYRIERIYRGDSWDR--------SA-DS--PLAEP------GLE--VRE--------------GDYLLSI--A-------
F2L4Y9_THEU7/718-804.WRVAKIFVGDPANE--------GE-RS--PLAAP------GLD--VKE--------------GDCVLSI--G-------
Q020G3_SOLUE/804-893.YRFKKIYAGESWNP--------QV-QS--PLTQP------GLN--VNE--------------GDYLLAV--N-------
A3UJ31_9RHOB/772-861.YRIARIYSGESWNP--------FL-TA--PLASP------GLD--VSA--------------GDFILAI--N-------
E1ICY4_9CHLR/759-849.YRISRILRGDTWDE--------RA-SS--PLGRP------GLG--LQV--------------GDRLVAI--N-------
C2G1Q2_9SPHI/768-857.YQISKIYTRMEWNP--------DL-QA--PLAEP------GIE--VSE--------------GMFIVSV--N-------
A4BZR3_9FLAO/755-842.YQFKKIYKGERWNP--------TI-TA--PLGAP------GIN--VHE--------------GDYLLAI--N-------
D9PGC5_9ZZZZ/747-836.YRIKKIISGAPWDS--------EV-RS--PLLMP------GLK--VKA--------------GDYILAV--N-------
B0VF46_CLOAI/747-837.YEIIRILKGDYWLS--------EN-RS--PFMNP------GLN--VSE--------------GWIIKAV--N-------
A9BIW8_PETMO/751-841LYKISHIVKGDIWDE--------KN-KP--PLLGP------GVE--VKE--------------GDYLLAI--N-------
B3QU45_CHLT3/747-837.FEVTGLPKGDFWKE--------GE-AS--PLHTP------GVN--VQV--------------GDLILEV--N-------
D9QMJ3_BRESC/796-884.WCITKIYGPTAFSP--------DV-TG--PLAQP------GVD--ARV--------------GDCVLSV--D-------
C6WJJ9_ACTMD/754-843.WRIARVIPGETSDP--------AA-RS--PLSAP------GVA--VRA--------------GDVITAV--D-------
E4NAZ7_KITSK/757-844.WRVARVLPGESSDP--------RA-RS--PLAAP------GAA--VRP--------------GDALLAV--N-------
D9Y1R2_9ACTO/760-849.WRVDRILPAETSDP--------EA-RS--PLAAP------GVA--VRP--------------GDAIVAV--A-------
C7Q5E5_CATAD/793-881.WRIVKILPGDNSVP--------AA-RS--PLLAP------GIA--ARV--------------GDAITAV--D-------
D6B076_9ACTO/767-856.WRVERVLPSETSDP--------HA-YS--PLAAP------GVA--VRA--------------GDAILAV--D-------
B4D285_9BACT/824-912.YRIAHIIIAAPWD.--------NV-RS--PLMQP------GVN--VHE--------------GDWLLAV--D-------
D4VA73_BACVU/751-841.YRIDKILPGAIYSQ--------KL-RS--PLTEP------GIG--VKE--------------GDYITAI--D-------
E1WP31_BACF6/758-848.FRLEKIFPGASWSK--------EL-RS--PLTEP------GVD--VRV--------------GEYIVAI--D-------
E4RW77_LEAB4/768-855.YKVGKIIRGASWDA--------EV-RS--PLEKS------GIK--..E--------------GSYILEV--N-------
B5G810_9ACTO/757-846.WRVDRVLPSETSDP--------HA-RS--PLAGP------GIA--VRA--------------GDALLAI--G-------
D0TG11_9BACE/757-847.FRLEKILPGASWSK--------EL-RS--PLTEP------GVE--AKA--------------GEYIVAI--D-------
C1N9P1_MICPC/828-915GYRITHIVGGDQWDD--------LT-GG--ALRKP------GLN--VAV--------------GDAIVAL--N-------
D9UTL0_9ACTO/419-505.WELRRILPGESSDP--------RA-RS--PLAGT------GIR--..E--------------GAVLTHV--D-------
D2ARY8_STRRD/732-815.WQVDRVLPGESSDV--------HA-RS--PLAVP------GAG--IQQ--------------GETLLAV--D-------
B5GPX5_STRCL/828-913.WVVRRILPGESSDS--------KA-RS--PLAGT------GIP--..E--------------GAVITHV--D-------
B5HKU3_9ACTO/746-831.WTVRRILPGDSSDS--------KA-RS--PLAGT------GIR--..E--------------GAVLTHV--D-------
D6B1U4_9ACTO/818-904.WVLRRILPGDSSDT--------KA-RS--PLAGT------GIR--..E--------------GAALTHV--D-------
D9WLZ7_9ACTO/795-883.WQISRILPGESSDS--------RA-RS--PLAGS------GIR--..E--------------GARLTHV--D-------
D5ZWH5_9ACTO/838-925.WTVKRILAGDSSDS--------RA-RS--PLAGT------GIR--..E--------------GAVLTQV--D-------
D6K3M6_9ACTO/906-993.WVVKRILPGDSSDS--------RA-RS--PLAGA------GIR--..D--------------GAVLTHV--D-------
E4NBJ1_KITSK/740-825.WLVDRILPGESSDP--------KA-RA--PLAGH------GLR--..D--------------GDELLAV--D-------

PF04495

Q2LYW0_DROPS/69-205----GANESVWHILE--------VH.PN--SPAEL------AG.--LRAY-------------SDYVIGA--D.......
Q0U7P0_PHANO/83-216----.LAEDVWHILD--------VA.PN--SPADV------AG.--LLPY-------------GDYVIGS--PE......
Q6BX19_DEBHA/130-306----.TATYVWRILN--------TH.HN--SPAFQ------AQ.--LIPY-------------SDYIIGC--DSAYPQDA
A5DBW3_PICGU/154-329----.TATYVWRILQ--------TH.MG--SPAFQ------AQ.--LVPY-------------SDYIIGC--DSASPDEP
GORS2_MOUSE/69-205----GANENVWHVLE--------VE.SN--SPAAL------AG.--LRPH-------------SDYIIGA--D.......
Q5CNE5_CRYHO/133-257----...TKGIRVVN--------IQ.DS--SPAQA------AG.--LISN-------------EDYIVAS--S.......
Q5F353_CHICK/69-205----GANENVWHVLE--------VE.PN--SPAAL------AG.--LRPH-------------SDYIIGA--D.......
Q5U3V8_DANRE/70-206----GANENVWHVLD--------VE.SN--SPAAL------AG.--LQEH-------------SDFIVGA--D.......
Q4SNY6_TETNG/69-235----GANENVWHVLE--------VE.PN--SPAAL------AG.--LRPH-------------TDYIIGA--D.......
Q0IEU2_AEDAE/69-205----GANENVWHILE--------VH.PS--SPAEE------AG.--LIPF-------------TDYIIGA--D.......
A6ZZA4_YEAS7/141-282----.ASTFTYHILN--------VNIPD--GPAQS------AG.--LIPD-------------EDYIIGC--QD......
Q5KDT5_CRYNJ/68-205----HALESVYHVLD--------VL.EG--SPAEM------AG.--LVPW-------------GDYVLAW--SG......
Q6PC76_DANRE/69-205----GANENVWHVLE--------VE.PN--SPAAL------AG.--LRPH-------------TDYIIGA--D.......
YAT2_SCHPO/80-213----PAVDAIWHILN--------VI.DD--SPVAR------AS.--LVPY-------------EDYIVGT--PE......
GORS1_MOUSE/68-204----RASEHVWHVLD--------VE.PS--SPAAL------AG.--LCPY-------------TDYIVGS--D.......
Q4UCI6_THEAN/70-205----.CLDEGAHIVH--------VY.DK--SPAQK------AG.--LMPI-------------TDYLLGT--NL......
Q54C46_DICDI/73-210----KTLENVWHVLD--------VY.LN--SPAHE------AE.--LQTR-------------LDYIVGT--PD......
Q2UN33_ASPOR/80-214----.STQHIWHVLN--------IPSPL--SPAYR------AG.--LLPH-------------SDYIIGT--PS......
A7ARE9_BABBO/70-205----.AMDEGAHVIN--------VH.DG--SPAKK------AG.--LMPI-------------TDYLLGT--NL......
E9BPI9_LEIDB/103-265----ACPERCVHVVD--------VL.EG--SPAAC------STE--LQAN-------------RDYIIGM--QTVQE...
Q4Q3U9_LEIMA/103-265----ACPERCVHVVD--------VL.EG--SPAAC------STE--LQAN-------------RDYIIGM--QTVQE...
Q7QJA4_ANOGA/69-205----GANENVWHILE--------VH.PS--SPAEE------AG.--LIPF-------------TDYIIGA--D.......
A1DMR0_NEOFI/97-231----.STQHIWHVLS--------IPSPL--SPAYR------AG.--LLPH-------------SDYIIGT--PS......
Q6GLD6_XENTR/71-207----GANEHVWHVLD--------VE.PN--SPAAL------AG.--LQSH-------------TDYIVGS--D.......
Q28J72_XENTR/69-205----GANENVWHVLE--------VE.PN--SPAAL------AG.--LRAH-------------SDYIIGA--D.......
Q5CZ04_CRYPI/133-257----...TKGIRVVN--------IQ.DS--SPAQA------AG.--LISN-------------EDYIVAS--S.......
Q5ZK65_CHICK/69-205----GANEHVWHVLD--------VE.PA--SPAAV------GG.--LQPY-------------TDYIVGS--D.......
Q22G20_TETTS/89-227----NSHDNTFKVVT--------VD.EN--SPAKI------AG.--LQAK-------------QDYIIGL--KK......
Q2YDP4_BOVIN/69-205----RASEHVWHVLD--------VE.PS--SPAAL------AG.--LRPY-------------TDYVVGS--D.......
Q386P4_TRYB2/73-244----KCVERCWHVVD--------VI.PG--SPVAK------CGE--IKEG-------------RDYIIGI--QKADE...
Q4N0A2_THEPA/102-237----.CLDEGAHIVH--------VY.DK--SPAQK------AG.--LMPI-------------TDYLLGT--NL......
Q4PFN7_USTMA/83-237----QALSHVWHILE--------IL.EG--SPAES------AG.--LVPF-------------GDFVIGW--PG......
Q2HFQ7_CHAGB/78-211----.VVSNIWHVLD--------VP.AN--SPADA------AG.--LLPY-------------SDYILGT--PE......
Q0CI81_ASPTN/81-215----.STQNIWHVLN--------IPSPL--SPAYR------AG.--LLPH-------------SDYIIGT--PS......
A5DW42_LODEL/191-326----.TATYVWRILN--------TH.PG--SPAFR------SQ.--LVPH-------------SDFIIGC--DSAFPN.D
A7EGH4_SCLS1/79-212----.TVSNIWHILD--------VP.AN--SPADL------AG.--LLPY-------------SDYILGT--PE......
A6RJ89_BOTFB/62-195----.TVSNIWHILD--------VP.AN--SPADL------AG.--LLPY-------------SDYILGT--PE......

PF12812

B8MUN1_TALSN/264-341LYAIACR..GVYVCE-----------AA--GSFKI......DDN..TPS--------------GWIIDSV--G-------
NM111_PICST/379-456CYCIPVK..GVFIND-----------AS--GSFEF......ASY..EKS--------------GWLLETV--D-------
NM111_PICGU/388-465CFCIPVR..GVFIND-----------GS--GSFEL......SPF..EKN--------------GWLLEYV--D-------
NM111_LODEL/379-456CYCLPVR..GLYVCD-----------GS--GSFEF......SNQ..DTL--------------GFIVETV--D-------
B9W6Q0_CANDC/376-453CYGLPVK..GVFVNG-----------GT--GSFEF......SPQ..DTL--------------GWMIESV--D-------
C5MEA8_CANTT/370-447SFGLPVK..GVFVNH-----------GA--GSFEF......SSQ..DTL--------------GWFIQAV--D-------
NM111_YEAS7/392-469FYALPVR..GVFLSS-----------AS--GSFNF......DSK..ERV--------------GWIVDSI--D-------
NM111_CANGA/374-451FYALPIR..GVFLSS-----------AS--GSFNF......DNK..EKI--------------GWIVDSV--N-------
NM111_ASHGO/372-449YYAIPVR..AVFLSS-----------AT--GSFCF......DTK..EKL--------------GWIVDEV--N-------
NM111_KLULA/388-465CYALPVK..GVFVAS-----------AT--GSFDL......DPK..EKT--------------GWVIDFV--D-------
C4R214_PICPG/366-443LYAIPVR..GVFANR-----------AS--GSFTL......DTR..DRC--------------GWIIDSL--D-------
NM111_YARLI/360-439IYAIPVR..GVYVSE-----------VG--GSFRL......DGQGNESK--------------GWVVDSI--D-------
B6JWG1_SCHJY/372-448QYALPVR..RVFISE-----------PT--GSFYL......EG...SDY--------------GYLLESI--A-------
B2RIG1_PORG3/398-471SYGVSYG..VEVTSV-----------SS--GKFKD......AG...IKK--------------GFIILSI--N-------
A6SSR9_BOTFB/12-90QQISKLHSEVYVAAR-----------TR--GSPSY......QYN..LTP--------------TNFVTHV--N-------
B2WNT3_PYRTR/845-923QQISKIHSDVYISSR-----------AR--GSPAY......MYG..LAP--------------TNFVTHV--N-------
C4Y709_CLAL4/134-212QLMEKIPSEVYVARK-----------SA--GGPMT......QYG..ISN--------------SVFITHV--N-------
NM111_KLULA/861-937QVKTSIPSEVYAVSR-----------GT--SSLAL......QYG..IEV--------------TNFITHV--N-------
Q6CHS4_YARLI/371-442STNEPID..GVIVAC-----------GG--PTD.............VNC--------------RSKLYKI--N-------
B6QC43_PENMQ/337-413CWKVPLK..GMFLAS-----------SA--INFSL......GD...ESN--------------SYIISSI--N-------
B9H391_POPTR/179-254NFCFQCG..LVYVSD-----------PG--YMLSR......AG...IPR--------------HAIIKKF--A-------
B8AHP7_ORYSI/375-450NFRFKCG..LVYVAE-----------AG--YMLSR......AS...VPR--------------HAIIKKL--A-------
A9RQ61_PHYPA/347-422NLHFVCG..IVYVAE-----------PG--YMLSC......AG...VPR--------------HAIIKKM--A-------
A8JH35_CHLRE/368-444NNRAVVG..QVYVAE-----------PG--YMLGR......AN...VPK--------------CAIITGL--N-------
C1EGI7_MICSR/349-424NFQLPVG..SVYVAE-----------PG--YVLGL......AG...LSK--------------HAIITSL--N-------
C1N456_MICPC/359-434NFQLPCG..GVYVAE-----------PG--YVLGV......AN...VPK--------------HAILTSL--G-------
B6K3R7_SCHJY/399-475SYQCAFNS.GTFVA.-----------AS--GMLNW......SG...GTR--------------DFLVTKL--A-------
YH05_SCHPO/393-469SYQFSLNS.GTYVA.-----------SS--GMLNW......SS...GTR--------------DFLVTRL--A-------
B8FNF0_DESAA/337-420DLDIASD..GVYLSQ-----------AE--LGSTFGSVGYSSSRNPDRK--------------GVVVQGI--N-------
NM111_MAGO7/393-469LYGVACK..GVYVCE-----------AT--GSFRF.......ET..SDN--------------GWILQTI--D-------
B2ASP9_PODAN/396-472LYGVACK..GVYVCE-----------AG--GSWRF.......ES..SEC--------------GWLIQTV--D-------
B2WNT3_PYRTR/372-451LYAISLKGAGVYVCE-----------AA--GSFRF......ADG..YTS--------------GWLIQEV--D-------
C0NX23_AJECG/394-470LYAIACK..GVYVCE-----------AA--GSFKL.......EN..TFS--------------GWIVDTV--D-------
B6HPJ1_PENCW/491-567LYAIATR..GVYVCE-----------SA--GSFKL.......EN..TVA--------------GWIIDSI--D-------

PF13180

B5GKK1_9ACTO/268-357-------------------------------------D-----TII...DSG.......PT-------------------
Q7VJB0_HELHP/178-253-------------------------------------G-----AKV...QTS.......DE-------------------
C3XFI7_9HELI/161-241-------------------------------------D-----IAP...KDW.......AE-------------------
A7ZFX4_CAMC1/179-256-------------------------------------G-----IKP...KSL.......RE-------------------
Q0S4Y2_RHOSR/404-487-------------------------------------D-----RVI...TSG.......DA-------------------
A4BWR3_9FLAO/100-182-------------------------------------K-----DTLFSKNLR.......TE-------------------
D3UIB8_HELM1/171-246-------------------------------------N-----KIA...RKS.......LN-------------------
B5JGE0_9BACT/505-583-------------------------------------Q-----SRV....DE.......KQ-------------------
D1BL26_VEIPT/269-359-------------------------------------G-----KDI...TTL.......LE-------------------
C4FCZ3_9BIFI/468-561-------------------------------------G-----HAV...NST.......AS-------------------
C5EYC1_9HELI/179-257-------------------------------------G-----EAI...PNV.......SQ-------------------
A6DE20_9PROT/159-227-------------------------------------N-----KKA....TP.......KN-------------------
D3HBS1_STRM6/289-384-------------------------------------D-----KEI...ASS.......TD-------------------
B6BJX8_9PROT/225-327-------------------------------------C-----NKIENDGTVEFRHHQFTS-------------------
B1VP64_STRGG/452-541-------------------------------------D-----TVI...DSG.......PT-------------------
D2R087_PIRSD/256-349-------------------------------------E-----VPV...IDD.......LH-------------------
B0R2X2_HALS3/244-350-------------------------------------G-----TRV...HTL.......ED-------------------
B6JPD1_HELP2/170-247-------------------------------------N-----QKV...HSL.......AE-------------------
A5YS57_9EURY/308-391-------------------------------------G-----IQI...TNN.......ER-------------------
O34248_WOLSU/167-244-------------------------------------G-----RAI...GSR.......SE-------------------
B9CXW4_WOLRE/332-409-------------------------------------G-----EKM...ESL.......RE-------------------
D4FIA0_STAEP/304-394-------------------------------------G-----KQI...KDD.......TD-------------------
E7FRR7_9LACO/328-425-------------------------------------G-----KKV...SGL.......SS-------------------
A2RH30_STRPG/301-396-------------------------------------G-----KIV...NSI.......SD-------------------
A6C000_9PLAN/277-369-------------------------------------G-----IDV...LDQ.......NH-------------------
Q30TR4_SULDN/163-240-------------------------------------T-----RKV...KDS.......AS-------------------
C5EVE7_9FIRM/145-228-------------------------------------D-----TMVA.SESL.......DV-------------------
B4V7R0_9ACTO/417-506-------------------------------------G-----KQI...DSG.......PS-------------------
C9A6A9_ENTCA/295-392-------------------------------------D-----TEV...STT.......TD-------------------
D1XW98_9BACT/96-178-------------------------------------N-----IDI...TNK......DTK-------------------
A0AKF7_LISW6/118-196-------------------------------------G-----QAF...QSS.......QE-------------------
A0RM44_CAMFF/175-252-------------------------------------S-----KVP...NNL.......RE-------------------
B6BLX6_9PROT/163-240-------------------------------------G-----KKV...KDS.......AT-------------------
C9ZC44_STRSW/506-595-------------------------------------D-----HVI...DSG.......PT-------------------
B1XQ68_SYNP2/485-563-------------------------------------N-----YRT....NA.......EQ-------------------
A9B2Z4_HERA2/473-551-------------------------------------G-----WRI....DE.......DG-------------------
A6C5H9_9PLAN/245-325-------------------------------------G-----RPI...RSV.......NQ-------------------
Q315Q4_DESDG/369-449-------------------------------------G-----AQV...NSL.......WD-------------------
D5SYB3_PLAL2/269-351-------------------------------------N-----IPI...ARL.......GN-------------------
C3XM71_9HELI/174-251-------------------------------------G-----EMI...SNL.......AS-------------------
C0D033_9CLOT/153-236-------------------------------------D-----KVVA.NESL.......TI-------------------
Q1D977_MYXXD/477-552-------------------------------------G-----WKV....DG.......AT-------------------
A7VHN2_9CLOT/119-202-------------------------------------D-----YEIQESDDL.......DY-------------------
A5Z6X7_9FIRM/108-190-------------------------------------G-----KEVT.GVDI.......NN-------------------
A3YT34_CAMJU/170-244-------------------------------------G-----LPA...NDL.......RK-------------------
C2LWC8_STAHO/306-396-------------------------------------S-----KKV...DDD.......TD-------------------
C8X5D5_DESRD/676-755-------------------------------------D-----RAE...TDV.......AS-------------------
B2IZX7_NOSP7/201-295-------------------------------------G-----VTV...GDT.......GD-------------------
B5HUE3_9ACTO/403-492-------------------------------------D-----HVI...DSG.......PT-------------------
D2QHW4_SPILD/97-182-------------------------------------G-----VDL...KTR.......KD-------------------
B6W6V2_9FIRM/283-372-------------------------------------G-----EKV...KDM.......SN-------------------
A2TY74_9FLAO/100-182-------------------------------------S-----DTLFGKNLR.......TG-------------------

PF00595

DVL1_MOUSE/251-336-------------------------------------D.....VNF---ENM-------.S-------------------
ZO1_MOUSE/23-107-------------------------------------G.....VSM---DNV-------.E-------------------
ZO1_MOUSE/186-261-------------------------------------G.....TVT---ENM-------.S-------------------
ZO1_MOUSE/423-501-------------------------------------N.....VDF---TNI-------.I-------------------
AFAD_HUMAN/1009-1090-------------------------------------G.....RSL---VGL-------.S-------------------
PTN3_HUMAN/510-595-------------------------------------G.....RDI---SEH-------.T-------------------
SP4B_BACSU/103-184-------------------------------------G.....QKI---EKM-------.N-------------------
CTPA_SYNP2/102-182-------------------------------------G.....IDT---RNI-------.G-------------------
PDLI1_RAT/5-82-------------------------------------G.....EDT---SSM-------.T-------------------
APBA1_HUMAN/656-740-------------------------------------G.....TSL---VGL-------.P-------------------
APBA2_MOUSE/569-653-------------------------------------G.....TSL---VGL-------.P-------------------
APBA2_MOUSE/660-733-------------------------------------G.....QSV---VAT-------.A-------------------
ZO1_HUMAN/23-107-------------------------------------G.....VSM---DNV-------.E-------------------
ZO1_HUMAN/186-261-------------------------------------G.....TVT---ENM-------.S-------------------
ZO1_HUMAN/423-501-------------------------------------N.....VDF---TNI-------.I-------------------
DLG1_DROME/216-300-------------------------------------D.....VSV---VDV-------.P-------------------
DLG1_DROME/330-418-------------------------------------GS...EKNL---ENV-------.T-------------------
DLG1_DROME/506-584-------------------------------------N.....VNL---THA-------.T-------------------
PDLI4_HUMAN/4-81-------------------------------------G.....EST---ELM-------.T-------------------
DSH_DROME/252-337-------------------------------------D.....VNF---ENM-------.T-------------------
DVL1L_HUMAN/251-336-------------------------------------D.....VNF---ENM-------.S-------------------
DVL2_XENLA/254-339-------------------------------------D.....INF---ENM-------.S-------------------
EM55_TAKRU/73-151-------------------------------------G.....KSV---ANQ-------.T-------------------
EM55_HUMAN/71-149-------------------------------------G.....TNV---TNH-------.S-------------------
GSPC_KLEPN/190-270-------------------------------------G.....LDL---RDK-------.E-------------------
DEGQ_ECOLI/257-346-------------------------------------G.....KPL---NSF-------.A-------------------
DEGQ_ECOLI/365-444-------------------------------------R.....DRV---NSI-------.A-------------------
DEGS_ECOLI/248-336-------------------------------------N....KPAI---SAL-------.E-------------------
DEGS_HAEIN/242-322-------------------------------------N.....QEG---ISA-------.R-------------------
HTOA_HAEIN/268-358-------------------------------------G.....QKI---SSF-------.A-------------------
HTOA_HAEIN/377-455-------------------------------------R.....QMI---ENI-------.R-------------------
DEGPL_BARHE/289-378-------------------------------------G.....EKI---NDV-------.R-------------------
DEGP_ECOLI/279-368-------------------------------------G.....KPI---SSF-------.A-------------------
DEGP_SALTY/280-369-------------------------------------G.....KPI---SSF-------.A-------------------
DEGP_SALTY/386-464-------------------------------------Q.....QPV---KNI-------.A-------------------
LIMK1_HUMAN/165-255-------------------------------------G.....TPI---RNV-------.P-------------------
LIMK1_MOUSE/165-255-------------------------------------G.....TPI---RNV-------.P-------------------
LIMK1_RAT/165-255-------------------------------------G.....TPI---RNV-------.P-------------------
LIMK2_CHICK/152-236-------------------------------------G.....API---RTL-------.Q-------------------
LIMK2_HUMAN/152-236-------------------------------------G.....TPV---RTL-------.R-------------------
LIMK2_RAT/152-236-------------------------------------G.....TPV---RTL-------.R-------------------
LIN2_CAEEL/546-624-------------------------------------G.....MSV---ANR-------.S-------------------
NOS1_HUMAN/17-96-------------------------------------G.....RPL---VDL-------.S-------------------
NOS1_RAT/17-96-------------------------------------D.....RPL---VDL-------.S-------------------
PRC_HAEIN/244-328-------------------------------------QATGDIEDV---VGW-------.R-------------------
DLG4_RAT/65-149-------------------------------------E.....VDV---REV-------.T-------------------
DLG4_RAT/160-244-------------------------------------S.....VGL---EDV-------.M-------------------
DLG4_RAT/313-391-------------------------------------G.....VDL---RNA-------.S-------------------
PTN4_HUMAN/516-602-------------------------------------G.....RDI---AEH-------.T-------------------
PTP1_CAEEL/616-703-------------------------------------G.....RDV---STM-------.S-------------------
SIPA1_MOUSE/682-754-------------------------------------G.....QTL---PKL-------.G-------------------
APBA1_HUMAN/746-820-------------------------------------G.....QSV---VAT-------.P-------------------
RSEP_ECOLI/203-277-------------------------------------G.....QPL---TQW-------..-------------------
Y918_HAEIN/202-273-------------------------------------L.....TAL---P..-------.W-------------------
PSMD9_YEAST/99-191-------------------------------------N.....VHA---ANH-------.S-------------------
NM111_YEAST/290-375-------------------------------------G.....ETI---SSF-------MQ-------------------
YQI7_CAEEL/25-114-------------------------------------G.....ADF---TMM-------.T-------------------
PRC_ECOLI/238-320-------------------------------------QTGKPMVDV---IGW-------.R-------------------

PF14685

D0KPY8_SULS9/713-798-------------------------------------G-----ED.---.AN-------GN-------------------
TRIC_SULTO/556-640-------------------------------------G-----EEV---K..-------YN-------------------
TRI_THEVO/723-810-------------------------------------G-----IPI---GKG-------KS-------------------
TRI_THEAC/763-849-------------------------------------G-----ETV---GAG-------SN-------------------
Q4J6J4_SULAC/709-795-------------------------------------G-----EKV---RK.-------GS-------------------
D6TD68_9CHLR/771-861-------------------------------------G-----QRV---SSE-------RT-------------------
A7NMU6_ROSCS/788-877-------------------------------------S-----WRV---GRD-------VS-------------------
A5US97_ROSS1/783-872-------------------------------------G-----HRV---GRN-------VS-------------------
D3Q8U1_STANL/765-853-------------------------------------G-----QPV---GPT-------TS-------------------
Q8ZXG0_PYRAE/721-807-------------------------------------G-----VRL---GPN-------AP-------------------
B1KFH4_SHEWM/759-846-------------------------------------G-----QPL---DAS-------IN-------------------
A8UNS9_9FLAO/762-851-------------------------------------G-----TKL---SSG-------IN-------------------
E8WXR8_ACISM/803-890-------------------------------------G-----KPL---TAA-------ED-------------------
D2AWH2_STRRD/739-825-------------------------------------G-----QPV---GPS-------AG-------------------
E6PEL4_9ZZZZ/754-843-------------------------------------G-----ARL---SAE-------IA-------------------
F2L4Y9_THEU7/718-804-------------------------------------G-----TAL---GPD-------TP-------------------
Q020G3_SOLUE/804-893-------------------------------------G-----QEL---QGT-------ED-------------------
A3UJ31_9RHOB/772-861-------------------------------------G-----QDL---TAS-------DN-------------------
E1ICY4_9CHLR/759-849-------------------------------------G-----RRL---SAT-------RS-------------------
C2G1Q2_9SPHI/768-857-------------------------------------G-----VEL---TAD-------MN-------------------
A4BZR3_9FLAO/755-842-------------------------------------G-----VSL---TSK-------MN-------------------
D9PGC5_9ZZZZ/747-836-------------------------------------G-----QKL---DIN-------KA-------------------
B0VF46_CLOAI/747-837-------------------------------------G-----IPV---TKT-------IP-------------------
A9BIW8_PETMO/751-841-------------------------------------G-----IEI---KDK-------.I-------------------
B3QU45_CHLT3/747-837-------------------------------------G-----QSL---SKN-------QS-------------------
D9QMJ3_BRESC/796-884-------------------------------------D-----RAV---SAD-------MD-------------------
C6WJJ9_ACTMD/754-843-------------------------------------G-----RQV---DPL-------TG-------------------
E4NAZ7_KITSK/757-844-------------------------------------G-----RPV---DPV-------TG-------------------
D9Y1R2_9ACTO/760-849-------------------------------------G-----QPV---DPV-------TG-------------------
C7Q5E5_CATAD/793-881-------------------------------------G-----LPV---PPR-------VG-------------------
D6B076_9ACTO/767-856-------------------------------------G-----QPV---DPV-------TG-------------------
B4D285_9BACT/824-912-------------------------------------G-----RPL---DTK-------QD-------------------
D4VA73_BACVU/751-841-------------------------------------G-----IST---ATV-------DN-------------------
E1WP31_BACF6/758-848-------------------------------------G-----VPT---NTV-------KD-------------------
E4RW77_LEAB4/768-855-------------------------------------G-----LPI---STN-------KD-------------------
B5G810_9ACTO/757-846-------------------------------------G-----RPV---DPL-------LG-------------------
D0TG11_9BACE/757-847-------------------------------------G-----VPT---NSV-------ND-------------------
C1N9P1_MICPC/828-915-------------------------------------R-----VTL---TEE-------VG-------------------
D9UTL0_9ACTO/419-505-------------------------------------G-----RPV---DPV-------TG-------------------
D2ARY8_STRRD/732-815-------------------------------------G-----RPV---PPQ-------.G-------------------
B5GPX5_STRCL/828-913-------------------------------------G-----RPV---DPV-------AG-------------------
B5HKU3_9ACTO/746-831-------------------------------------G-----RPV---DEL-------AG-------------------
D6B1U4_9ACTO/818-904-------------------------------------G-----RPV---DPV-------TG-------------------
D9WLZ7_9ACTO/795-883-------------------------------------G-----RQV---DPV-------AG-------------------
D5ZWH5_9ACTO/838-925-------------------------------------G-----RPV---DPV-------AG-------------------
D6K3M6_9ACTO/906-993-------------------------------------G-----RPV---DPV-------TG-------------------
E4NBJ1_KITSK/740-825-------------------------------------G-----RPP---DPV-------RG-------------------

PF04495

Q2LYW0_DROPS/69-205...AIRH..............................ENDDLFTLI---DTH------EQQ...................
Q0U7P0_PHANO/83-216...GLVR..............................GESGLGELV---EDF------LNR...................
Q6BX19_DEBHA/130-306EGKGLLAK............................GGESLLSRTV---MSY------YNLHYSAS..............
A5DBW3_PICGU/154-329QGQGLLTS............................GGEALLSRVV---LNY------YNQHYSKT..............
GORS2_MOUSE/69-205...TVMN..............................ESEDLFSLI---ETH------EAK...................
Q5CNE5_CRYHO/133-257...TLMRP...........................FYSTDDFLVFV---KRN------DKV...................
Q5F353_CHICK/69-205...TVMN..............................ETEDLFSLI---ETH------EAK...................
Q5U3V8_DANRE/70-206...QVLQ..............................DSEDFFSLI---EAH------EGK...................
Q4SNY6_TETNG/69-235...TVMNEVSEAKGSHPSHLHPLWNVTCPFCSPSSSLQSEDLFSLI---ESH------EGK...................
Q0IEU2_AEDAE/69-205...SILH..............................ESEDLFTLI---ESH------KGR...................
A6ZZA4_YEAS7/141-282...GLLAT............................GGETLLQDIV---RSR------ANY...................
Q5KDT5_CRYNJ/68-205...GPLH..............................SENDFYNLI---EAH------VDK...................
Q6PC76_DANRE/69-205...TVMN..............................ESEDLFSLI---ETH------EGK...................
YAT2_SCHPO/80-213...GMMT..............................GEKALSDLI---ESH------LNR...................
GORS1_MOUSE/68-204...QILQ..............................ESEDFFTLI---ESH------EGK...................
Q4UCI6_THEAN/70-205...QLFY..............................DLDCVRIHV---ANK------VDK...................
Q54C46_DICDI/73-210...LILN..............................EQEDFFTLI---NNN------MYR...................
Q2UN33_ASPOR/80-214...GTLR..............................GESALGELV---EDH------LDR...................
A7ARE9_BABBO/70-205...QLFV..............................DSDCVRVHV---GER------VDE...................
E9BPI9_LEIDB/103-265TLITLIK..............................SQKDFYSRL---EAW------HEEQRWALERKQL.........
Q4Q3U9_LEIMA/103-265TLITLIK..............................SQKDFYCRL---EAW------HEEQRWALERKQF.........
Q7QJA4_ANOGA/69-205...SILH..............................ESEDLFTLI---ESH------EGR...................
A1DMR0_NEOFI/97-231...GTLR..............................GDAALGELV---EDH------LNR...................
Q6GLD6_XENTR/71-207...QILQ..............................ESEDFYALV---EAH------EGK...................
Q28J72_XENTR/69-205...TVMN..............................ESEDLFSLI---ETH------EGK...................
Q5CZ04_CRYPI/133-257...TLMRP...........................FYSTDDFLVFV---KKN------DKV...................
Q5ZK65_CHICK/69-205...QILQ..............................ESEDFFSLI---ESH------EGK...................
Q22G20_TETTS/89-227...YKYE..............................GLDELINII---FDN------EGQ...................
Q2YDP4_BOVIN/69-205...QILQ..............................ESEDFFSLI---ESH------EGK...................
Q386P4_TRYB2/73-244LVTALIK..............................DEDDLYTRV---ELW------RTAQSAALRRLQRNSFVPTGAS
Q4N0A2_THEPA/102-237...QLFY..............................GLDCVRIHV---ANK------VDK...................
Q4PFN7_USTMA/83-237...GVLQ..............................AEGDFYELV---EAH------TDR...................
Q2HFQ7_CHAGB/78-211...GVLH..............................GEGGLSELV---EDH------IGR...................
Q0CI81_ASPTN/81-215...GTLR..............................GESALGELV---EDH------LNR...................
A5DW42_LODEL/191-326GAKGLLRH............................GGEHLLSNTV---SSY------YNHHYSHS..............
A7EGH4_SCLS1/79-212...GVLH..............................GESGLGELV---EDH------IGR...................
A6RJ89_BOTFB/62-195...GVLH..............................GESGLGELV---EDH------IGR...................

PF12812

B8MUN1_TALSN/264-341-------------------------------------R-----QPT---RNL----------------------------
NM111_PICST/379-456-------------------------------------D-----MPT---PDL----------------------------
NM111_PICGU/388-465-------------------------------------D-----KPT---PNL----------------------------
NM111_LODEL/379-456-------------------------------------D-----KPV---ANL----------------------------
B9W6Q0_CANDC/376-453-------------------------------------D-----EIV---ENL----------------------------
C5MEA8_CANTT/370-447-------------------------------------D-----VPV---GNL----------------------------
NM111_YEAS7/392-469-------------------------------------N-----KET---PDL----------------------------
NM111_CANGA/374-451-------------------------------------Y-----QDT---PNL----------------------------
NM111_ASHGO/372-449-------------------------------------N-----QPT---PTL----------------------------
NM111_KLULA/388-465-------------------------------------N-----KET---PTL----------------------------
C4R214_PICPG/366-443-------------------------------------H-----KDT---PDL----------------------------
NM111_YARLI/360-439-------------------------------------D-----IDT---PDL----------------------------
B6JWG1_SCHJY/372-448-------------------------------------H-----KPV---PDL----------------------------
B2RIG1_PORG3/398-471-------------------------------------R-----QPV---SSG----------------------------
A6SSR9_BOTFB/12-90-------------------------------------G-----KPT---PDL----------------------------
B2WNT3_PYRTR/845-923-------------------------------------N-----VPT---PNL----------------------------
C4Y709_CLAL4/134-212-------------------------------------D-----QET---PDL----------------------------
NM111_KLULA/861-937-------------------------------------D-----QST---PDL----------------------------
Q6CHS4_YARLI/371-442-------------------------------------G-----KKI---SNL----------------------------
B6QC43_PENMQ/337-413-------------------------------------N-----HPT---RNV----------------------------
B9H391_POPTR/179-254-------------------------------------D-----DEI---SQL----------------------------
B8AHP7_ORYSI/375-450-------------------------------------G-----EDI---ENL----------------------------
A9RQ61_PHYPA/347-422-------------------------------------G-----EEI---DNL----------------------------
A8JH35_CHLRE/368-444-------------------------------------G-----KPT---PDL----------------------------
C1EGI7_MICSR/349-424-------------------------------------N-----VPT---PDL----------------------------
C1N456_MICPC/359-434-------------------------------------N-----TPT---PDL----------------------------
B6K3R7_SCHJY/399-475-------------------------------------N-----IPT---PNL----------------------------
YH05_SCHPO/393-469-------------------------------------N-----KPT---PTL----------------------------
B8FNF0_DESAA/337-420-------------------------------------G-----QPV---RNL----------------------------
NM111_MAGO7/393-469-------------------------------------N-----KKV---PDL----------------------------
B2ASP9_PODAN/396-472-------------------------------------H-----KKT---PDL----------------------------
B2WNT3_PYRTR/372-451-------------------------------------N-----QPT---PDL----------------------------
C0NX23_AJECG/394-470-------------------------------------K-----RPT---KNL----------------------------
B6HPJ1_PENCW/491-567-------------------------------------K-----RPV---RNL----------------------------

PF13180

B5GKK1_9ACTO/268-357----------LI......GEIW.THQPGD-----KVKITYKR......DGKERTTEVTL-----------
Q7VJB0_HELHP/178-253----------AE......WVMS.NLKKDS-----LAQVTLLR......NGKTLNLKVKV-----------
C3XFI7_9HELI/161-241----------LE......LIIS.NLMPDE-----VAQIKIKR......GENVKNIKVKA-----------
A7ZFX4_CAMC1/179-256----------LN......EMVL.FAPKGA-----RLDIIVKR......DREQLLFQVPV-----------
Q0S4Y2_RHOSR/404-487----------LI......AAIR.SHAPGD-----NVSITYTDG....NGSNTKTVDVTL-----------
A4BWR3_9FLAO/100-182----------AI......PKYL.KGRPNT-----EVKLQIYR......KSTDSLFNVKI-----------
D3UIB8_HELM1/171-246----------VE......WVIS.NLKEGE-----RVRVLVERK....IDKKTITKELSV-----------
B5JGE0_9BACT/505-583----------LK......RIVG.LLGAGK-----EVELLVSR......QGLLRTLKVTL-----------
D1BL26_VEIPT/269-359----------LK......ERID.AKSPGD-----TVLVSYTH......NGKMKSTQIKL-----------
C4FCZ3_9BIFI/468-561----------LL......GFVR.ATALGD-----KATLTIVR......DGKTMDVDVTL-----------
C5EYC1_9HELI/179-257----------FN......RVVF.DLKEGS-----TIPVRIQR......DGTIHNISVKV-----------
A6DE20_9PROT/159-227----------FS......KYVL.LGKVGE-----VVLIKTNK..........LTIPLRI-----------
D3HBS1_STRM6/289-384----------LQ......SALY.NHSIGD-----TIKITYYR......NGKEETTSIKL-----------
B6BJX8_9PROT/225-327----------YK......YYID.KKQLGE-----SVTVRVLR......DGKKQKISVQL-----------
B1VP64_STRGG/452-541----------LI......GEIW.TRKPGE-----KVTLTYER......DGKEATAEVTL-----------
D2R087_PIRSD/256-349----------LI......RLLS.GMFAGS-----EVTLTVERGSSTLLNARKLDLEVLL-----------
B0R2X2_HALS3/244-350----------VL......SLLALHTSPGD-----TVSVRLLR......DGDRRTVDVEL-----------
B6JPD1_HELP2/170-247----------FE......WVVS.NLKYQS-----LVKVEIKR......NHKIKEVTLKV-----------
A5YS57_9EURY/308-391----------LA......TVLIQNHSPGD-----TVELTIVS......GDTTRTVEIEL-----------
O34248_WOLSU/167-244----------LE......NQIY.GLAPGR-----EVRVSVMR......EGEVVSFETRV-----------
B9CXW4_WOLRE/332-409----------LN......ERIL.FAKKGE-----KLKFEVRR......GDEILKFNLAV-----------
D4FIA0_STAEP/304-394----------LR......TYLYESKKPGE-----TVTLKVIR......DGKTQDINVKL-----------
E7FRR7_9LACO/328-425----------LR......TALY.GHKVGD-----TVEIQYYH......KGELKKANVKL-----------
A2RH30_STRPG/301-396----------LQ......SSLY.GHDIND-----TIKVTFYR......GTTKKKADIKL-----------
A6C000_9PLAN/277-369----------LI......NLVS.LTPIDN-----RVSVVLLR......SGRKVNVMVEL-----------
Q30TR4_SULDN/163-240----------FM......RNIL.FSSIGS-----THNVKIKR......DNKIVTLRAIT-----------
C5EVE7_9FIRM/145-228----------LV......NNYI.KGKEGT-----PVEITVYR......ADKDEYVDLTV-----------
B4V7R0_9ACTO/417-506----------LI......SEIW.THKPGD-----VVKLTYVR......DGKPNTVDITL-----------
C9A6A9_ENTCA/295-392----------LQ......SALY.KHKVGD-----TITVTFYR......GDEEKTAEVKL-----------
D1XW98_9BACT/96-178----------FV......SQHL.RGDAGT-----SFILKVLR......PTTNKMMKLKI-----------
A0AKF7_LISW6/118-196----------FI......DYIH.GKKVGD-----TVKINYKH......GDKKEEANIKL-----------
A0RM44_CAMFF/175-252----------IN......EMIL.FAPKDA-----VLKFDINR......DGKNQSYSIKM-----------
B6BLX6_9PROT/163-240----------LM......RKIL.FSKVGS-----THSVKIKR......DSKYFTFKVKT-----------
C9ZC44_STRSW/506-595----------LI......GEIW.THRPGD-----KVTLTYTR......DGKTRTADVTL-----------
B1XQ68_SYNP2/485-563----------LN......HRLQ.NYQAGD-----TISITIFH......QDQLKTLAVTL-----------
A9B2Z4_HERA2/473-551----------LN......KRLA.DYPIGA-----TVQLSFFR......RDELLHVPVTF-----------
A6C5H9_9PLAN/245-325----------FK......NILG.IYPAGW-----TLPLVYRR......DEKKNTIYVRL-----------
Q315Q4_DESDG/369-449----------MH......KAGMQAAREKR-----PVVFGVQR......DGAMLSLELSV-----------
D5SYB3_PLAL2/269-351----------LK......HVLG.RKYAGD-----QLQLKILR......KKDPLEVTIPL-----------
C3XM71_9HELI/174-251----------FR......RVVF.DLKKGL-----VVPVQIKR......NGVSMEVQAQV-----------
C0D033_9CLOT/153-236----------LV......NNYI.KGQEGS-----QVHITVYR......QEKDEYVEMTL-----------
Q1D977_MYXXD/477-552----------LL......SRCE.ERRPGE-----TVRLTVFR......RDRLLEIPVVL-----------
A7VHN2_9CLOT/119-202----------LV......TKI..RGEEGT-----DVTLEIYR......PSERKYHTVTI-----------
A5Z6X7_9FIRM/108-190----------VV......TEM..KGEKGT-----TVDITVYR......ESEKKYIDFTI-----------
A3YT34_CAMJU/170-244----------LN......EKIL.FADRGS-----TLYFQVLR......DNMDLNISTEV-----------
C2LWC8_STAHO/306-396----------LR......TYLYQNKKPGE-----TVKLTVIR......DGKTKDVSVTL-----------
C8X5D5_DESRD/676-755----------LV......EAVR.ACTPGQ-----RVNLQVRR......GDTLQTVSLDT-----------
B2IZX7_NOSP7/201-295----------VL......ALLNSSDRIGK-----TVNLQVIR......GGVLIELAIAV-----------
B5HUE3_9ACTO/403-492----------LI......GEIW.THKPGD-----KVKITYER......DGQTHTVDLTL-----------
D2QHW4_SPILD/97-182----------RDGGPLDPGKLL.KGQNNT-----AVKLTVSR......YGQKAPLELSV-----------
B6W6V2_9FIRM/283-372----------LK......KLLL.NYSIGD-----KAKVQIVR......SGEKKSVDFEF-----------
A2TY74_9FLAO/100-182----------SV......PKYL.KGKPNT-----DVSLQVYR......KSNDSLFNVNI-----------

PF00595

DVL1_MOUSE/251-336----------ND------DAVRVLREIVSQ..TGPISLTVA-----------------------------
ZO1_MOUSE/23-107----------HA------FAVQQLRKSGK.....NAKITIR-----------------------------
ZO1_MOUSE/186-261----------LT------DAKTLIERSKG.....KLKMVVQ-----------------------------
ZO1_MOUSE/423-501----------RE------EAVLFLLDLPKG...EEVTILAQ-----------------------------
AFAD_HUMAN/1009-1090----------QE------RAAELMTRTSS.....VVTLEVA-----------------------------
PTN3_HUMAN/510-595----------HD------QVVMFIKASRESH.SRELALVIR-----------------------------
SP4B_BACSU/103-184----------DV------APFIQKAGKTG....ESLDLLIK-----------------------------
CTPA_SYNP2/102-182----------LE------EAAARMRGKKG....STVSLTVK-----------------------------
PDLI1_RAT/5-82----------HL------EAQNKIKGCVD.....NMTLTVS-----------------------------
APBA1_HUMAN/656-740----------LS------TCQSIIKGLKNQ...SRVKLNIV-----------------------------
APBA2_MOUSE/569-653----------LA------TCQGIIKGLKNQ...TQVKLNIV-----------------------------
APBA2_MOUSE/660-733----------HE------KIVQALSNSVG.....EIHMKTM-----------------------------
ZO1_HUMAN/23-107----------HA------FAVQQLRKSGK.....NAKITIR-----------------------------
ZO1_HUMAN/186-261----------LT------DAKTLIERSKG.....KLKMVVQ-----------------------------
ZO1_HUMAN/423-501----------RE------EAVLFLLDLPKG...EEVTILAQ-----------------------------
DLG1_DROME/216-300----------HA------SAVDALKKAGN.....VVKLHVK-----------------------------
DLG1_DROME/330-418----------HE------LAVATLKSITD.....KVTLIIG-----------------------------
DLG1_DROME/506-584----------HE------EAAQALKTSGG.....VVTLLAQ-----------------------------
PDLI4_HUMAN/4-81----------HL------EAQNRIKGCHD.....HLTLSVS-----------------------------
DSH_DROME/252-337----------ND------EAVRVLREVVQK..PGPIKLVVA-----------------------------
DVL1L_HUMAN/251-336----------ND------DAVRVLREIVSQ..TGPISLTVA-----------------------------
DVL2_XENLA/254-339----------ND------DAVRVLRDIVHK..PGPIVLTVA-----------------------------
EM55_TAKRU/73-151----------VD------QLQKILKETNG.....VVTMKII-----------------------------
EM55_HUMAN/71-149----------VD------QLQKAMKETKG.....MISLKVI-----------------------------
GSPC_KLEPN/190-270----------QA------RQVLAQLPELT.....EITLTVE-----------------------------
DEGQ_ECOLI/257-346----------EL------RSRIATTEPGT.....KVKLGLL-----------------------------
DEGQ_ECOLI/365-444----------EM------RKVLAAKPA.......IIALQIV-----------------------------
DEGS_ECOLI/248-336----------TM------DQVAEIRPGS......VIPVVVM-----------------------------
DEGS_HAEIN/242-322----------EM------MQIIANTKPNS.....KVLVTIL-----------------------------
HTOA_HAEIN/268-358----------EI------RAKIATTGAGK.....EISLTYL-----------------------------
HTOA_HAEIN/377-455----------EL------NKVLETEPS.......AVALNIL-----------------------------
DEGPL_BARHE/289-378----------DL------AKRIANMSPGE.....TVTLGVW-----------------------------
DEGP_ECOLI/279-368----------AL------RAQVGTMPVGS.....KLTLGLL-----------------------------
DEGP_SALTY/280-369----------AL------RAQVGTMPVGS.....KISLGLL-----------------------------
DEGP_SALTY/386-464----------EL------RKILDSKPS.......VLALNIQ-----------------------------
LIMK1_HUMAN/165-255----------LD------EIDLLIQETSR.....LLQLTLE-----------------------------
LIMK1_MOUSE/165-255----------LD------EIDLLIQETSR.....LLQLTLE-----------------------------
LIMK1_RAT/165-255----------LD------EIDLLIQETSR.....LLQLTLE-----------------------------
LIMK2_CHICK/152-236----------VE------EVEDLIRKTSQ.....TLQLLIE-----------------------------
LIMK2_HUMAN/152-236----------VE------EVEDAISQTSQ.....TLQLLIE-----------------------------
LIMK2_RAT/152-236----------VE------EVEDAINQTSQ.....TLQLLIE-----------------------------
LIN2_CAEEL/546-624----------VE------SLQEMLRDARG.....QVTFKII-----------------------------
NOS1_HUMAN/17-96----------YD------SALEVLRGIAS.....ETHVVLI-----------------------------
NOS1_RAT/17-96----------YD------SALEVLRGIAS.....ETHVVLI-----------------------------
PRC_HAEIN/244-328----------LE------DLVEKIKGKKG....TKVRLEIE-----------------------------
DLG4_RAT/65-149----------HS------AAVEALKEAGS.....IVRLYVM-----------------------------
DLG4_RAT/160-244----------HE------DAVAALKNTYD.....VVYLKVA-----------------------------
DLG4_RAT/313-391----------HE------QAAIALKNAGQ.....TVTIIAQ-----------------------------
PTN4_HUMAN/516-602----------HD------QVVLFIKASCERH.SGELMLLVR-----------------------------
PTP1_CAEEL/616-703----------HD------HVVQFIRSARSGLNGGELHLTIR-----------------------------
SIPA1_MOUSE/682-754----------PE------TAAQMLRSAP......KVCVTVL-----------------------------
APBA1_HUMAN/746-820----------HE------KIVHILSNAVG.....EIHMKTM-----------------------------
RSEP_ECOLI/203-277----------VT------FVMLVRDNPGK.....SLALEIE-----------------------------
Y918_HAEIN/202-273----------QD------FIKQVEQGE.......SFSIKVE-----------------------------
PSMD9_YEAST/99-191----------KL------QNIQMVVMKNED...RPLPVLLL-----------------------------
NM111_YEAST/290-375----------VD------KIQDENVGK.......EIQLVIQ-----------------------------
YQI7_CAEEL/25-114----------HD------RAVKFIKQSK......VLHMLVA-----------------------------
PRC_ECOLI/238-320----------LD------DVVALIKGPKG....SKVRLEIL-----------------------------

PF14685

D0KPY8_SULS9/713-798----------IY------SHLINKDQ...-----.VILDVITA.----DG..KNKRVTV-----------
TRIC_SULTO/556-640----------IL------SYLVNKDQ...-----.VVLDVITK.----G...KTKRVTV-----------
TRI_THEVO/723-810----------IY------EALVGKGN..R-----SVLVKIRKK.----DN..SVRSGFV-----------
TRI_THEAC/763-849----------IY------RVLSEKAG..T-----SARIRLSGK.----GG..DKRDLMI-----------
Q4J6J4_SULAC/709-795----------IN------SHFINKDQ...-----.AILEVLTS.----DG..KNRTVSV-----------
D6TD68_9CHLR/771-861----------PQ------ELLVNQAR..H-----EVQLTIEDA.----ET.QEIRTVTV-----------
A7NMU6_ROSCS/788-877----------PH------EVLVNQAG..C-----DVLLTFRKA.----DG..TLRAVTV-----------
A5US97_ROSS1/783-872----------PH------ELLINQAG..S-----DVLLTFMKM.----DG..TLRSVTV-----------
D3Q8U1_STANL/765-853----------VA------QLLVNQAD..Q-----EVRLSLRRG.----EA..DPHVVVV-----------
Q8ZXG0_PYRAE/721-807----------PE------YALLNRTS..D-----VVTVEVER..----GG..EVKAFTV-----------
B1KFH4_SHEWM/759-846----------LY------SLFVGKVD..K-----QVRLTVSPN.----GK..AKKAHTL-----------
A8UNS9_9FLAO/762-851----------PY------SLLEQTSG..R-----EINITVNSK.----PSLTDARTVLV-----------
E8WXR8_ACISM/803-890----------IQ------RPLEGTAG..H-----AVTLRLATG.----SA..PARDITI-----------
D2AWH2_STRRD/739-825----------PD------ERLVNQAD..Q-----EVQLTVRR..----GQ..DKRTFNV-----------
E6PEL4_9ZZZZ/754-843----------PE------RLLVNTAG..S-----EIALGIANK.----RG..DERTIVV-----------
F2L4Y9_THEU7/718-804----------PE------AALLNRAG..D-----VLWIETRRG.----D...AVRRFPV-----------
Q020G3_SOLUE/804-893----------VS------RLLENTSG..K-----HVLLKIASD.----AAGANAREITV-----------
A3UJ31_9RHOB/772-861----------IH------ALLQGTVD..N-----QITLTVADT.----ANGRSARDIIV-----------
E1ICY4_9CHLR/759-849----------PG------ELLVNQAG..A-----DLLLSIAPA.----AG.GEVRTLTI-----------
C2G1Q2_9SPHI/768-857----------IY------SLFNQTAG..K-----QTVIMVNSK.----PSLVGAKEVVV-----------
A4BZR3_9FLAO/755-842----------PY------LLLEQTAG..R-----EIYIKVNDI.----PS..EKEARTV-----------
D9PGC5_9ZZZZ/747-836----------PW------TSFEGLAD..K-----PVELTINDK.----PSIEGAKKILV-----------
B0VF46_CLOAI/747-837----------PE------RLTLNLAG..Q-----QVQLTVSSP.----DN.KEEKVVTI-----------
A9BIW8_PETMO/751-841----------PN------EFLVNYSG..K-----DVEIVVSSS.----DNIDHKRKYVV-----------
B3QU45_CHLT3/747-837----------FG------ELLVSMAG..Q-----EITLTVANA.----KK.ENMRRVRI-----------
D9QMJ3_BRESC/796-884----------IQ------SALEGTAG..R-----MVTLRLGAS.----SG.ANGRDVTV-----------
C6WJJ9_ACTMD/754-843----------PA------PLLVGTAG..K-----PVELVVRPGG----DG..DPRRVVV-----------
E4NAZ7_KITSK/757-844----------PA------PLLAGTAD..H-----PVELTVRGA.----DG..AERHPVV-----------
D9Y1R2_9ACTO/760-849----------PA------PLLVGTAG..K-----AVELTVSPA.----GG.GELRHAVV-----------
C7Q5E5_CATAD/793-881----------PA------ALLAGKAD..Q-----PTELVLQTQ.----SG..KRTVVVV-----------
D6B076_9ACTO/767-856----------PG------PLLVGTAG..K-----PVELTVSPA.----GG.GDPRHTVV-----------
B4D285_9BACT/824-912----------PW------AAFQGLGD..K-----AVMLTVNDK.----PNMEGSRNVLV-----------
D4VA73_BACVU/751-841----------IY------SLLAGKAN..V-----LTELSINRT.----ASSKGARKVVI-----------
E1WP31_BACF6/758-848----------MY------SLLVGKAEIPT-----EISLNVKPQ.----LS..GARKVVI-----------
E4RW77_LEAB4/768-855----------PY------YYFAGLNN..V-----AVELTYNDK.----PSLEGAKRAIV-----------
B5G810_9ACTO/757-846----------PG------PLLAGTAG..H-----VTELTIGPA.----GG.GEPRHVVV-----------
D0TG11_9BACE/757-847----------MY------KLLIGKAN..V-----PTELSLNSK.----PQLAGARKIVV-----------
C1N9P1_MICPC/828-915----------VD------EVLTGKGG..A-----EVMVTFKRG.----D....VVSVRV-----------
D9UTL0_9ACTO/419-505----------PA------PLLAGAAG..T-----SVELTFAST.----AG.GPPRRVAV-----------
D2ARY8_STRRD/732-815----------PA------SLLVGAAD..K-----AVELTLGG..----.....GRRVVV-----------
B5GPX5_STRCL/828-913----------PF------PMLAGAGG..T-----TVELTFRTD.----DG..GARRVAV-----------
B5HKU3_9ACTO/746-831----------PS------PLLAAAGG..T-----TVELTFTPA.----EG..EGRSRRV-----------
D6B1U4_9ACTO/818-904----------PY------PLLAGAGG..T-----TVELTFRAA.----EG.GRSRRVAV-----------
D9WLZ7_9ACTO/795-883----------PS------PLLTAAGG..T-----TVELTFASP.----DGEGPPRRVAV-----------
D5ZWH5_9ACTO/838-925----------PD------PLLAGAGG..T-----TVELTFRPA.----GGNGPPRRVAV-----------
D6K3M6_9ACTO/906-993----------PF------PLLAGAGA..T-----TVELTFTTA.----EGEGPSRRVAI-----------
E4NBJ1_KITSK/740-825----------PA------PLLAGTGG..S-----TVELTVRH..----EN..RIRRIAV-----------

PF04495

Q2LYW0_DROPS/69-205..........PL------KMYVYNLDDDA-----CREVTIKPNTAWGGE...GALGCGIGFGYLHRIPVQ
Q0U7P0_PHANO/83-216..........PL------RLIVYNHEYDV-----TRPVTITPSRGWGGE...GALGCVLGFGALHRIPPS
Q6BX19_DEBHA/130-306.....QEDNVPI------TLYVYNHDYDI-----LRPVTVNLSRSWGTGQNRGILGCDVGYGLLHRIPEV
A5DBW3_PICGU/154-329.....NDDFVPI------TLYVYNHDYDI-----LRPVTVNLSRSWGTGHNKGVLGCDVGYGLLHRIPEV
GORS2_MOUSE/69-205..........PL------KLYVYNTDTDN-----CREVIITPNSAWGGE...GSLGCGIGYGYLHRIPTR
Q5CNE5_CRYHO/133-257..........PL------SLVVYNTETEV-----TREIFITPNSGWGGK...GLLGCDIAAGPLYDIPLR
Q5F353_CHICK/69-205..........PL------KLYVYNTDTDN-----CREVVITPNSAWGGE...GSLGCGIGYGYLHRIPTR
Q5U3V8_DANRE/70-206..........PL------KLLIYNTETDK-----CREVVVTPNGAWGGE...GSLGCGIGYGYLHRIPAQ
Q4SNY6_TETNG/69-235..........GL------KLYVYNTDTDN-----CREVVITPNSAWGGD...GSLGCGIGYGYLHRIPTK
Q0IEU2_AEDAE/69-205..........PL------KMYVYNIDRDA-----CREVTITPNDKWGGE...GSLGCGIGYGYLHRIPIR
A6ZZA4_YEAS7/141-282..........DL------VLYVYNKVSDC-----VRPITV..HIGPDGR.....LGCNVGYGFLHRIPTV
Q5KDT5_CRYNJ/68-205..........PL------RLFVYNADLDN-----LREVVLYPTRQWGGE...GLIGCGIGYGLLHRIPRP
Q6PC76_DANRE/69-205..........GL------KLYVYNTDTDN-----CREVVITPNSAWGGE...GSLGCGIGYGYLHRIPTR
YAT2_SCHPO/80-213..........PL------RLYIYNHYRDS-----TRQVTIVPNRHWGGN...GAIGCGVGHGVLHRLPAP
GORS1_MOUSE/68-204..........PL------KLMVYNSESDS-----CREVTVTPNAAWGGE...GSLGCGIGYGYLHRIPTQ
Q4UCI6_THEAN/70-205..........EV------VLIVYNSVTET-----VRRALIVPRENWGGR...GTLGCDLAKGYIHRIPYV
Q54C46_DICDI/73-210..........PI------QLYVYSSLTEQ-----IRLVTITPNKNWGGS...GSLGCDIGFGLLHRIPTK
Q2UN33_ASPOR/80-214..........TL------VLWVYNSEFDV-----VREVELVPTRGWGGE...GALGAELGYGALHRLPVG
A7ARE9_BABBO/70-205..........DV------TLYVYNSVTET-----IRKTVITPRHGWGGS...GTLGCDLANGYIHRIPLV
E9BPI9_LEIDB/103-265FPNEMVEVPHVL------LFLVYNSENNT-----VEEVEV....EMGTNP.DAAVGISVATGLLHIIPSV
Q4Q3U9_LEIMA/103-265FPNERVEVPHVL------LFLVYNSESNT-----IEEVEV....EMGTNP.EAAVGISVATGLLHIIPSV
Q7QJA4_ANOGA/69-205..........PL------KMYVYNTDLDR-----CREVTITPNSKWGGE...GSLGCGIGYGYLHRIPIR
A1DMR0_NEOFI/97-231..........TL------VLWVYNSEFDV-----VREVELVPTRGWGGE...GALGAELGYGALHRLPVG
Q6GLD6_XENTR/71-207..........PL------KLLVYNTETDS-----CREVFVTPNSAWGGE...GSLGCGIGYGYLHRIPLK
Q28J72_XENTR/69-205..........PL------KLYVYNTDTDN-----CREVVITPNTAWGGE...GSLGCGIGYGYLHRIPTR
Q5CZ04_CRYPI/133-257..........PL------SLVVYNTETEV-----TREIFITPNSGWGGK...GLLGCDIAAGPLYDIPLR
Q5ZK65_CHICK/69-205..........PL------KLMVYNTEADS-----IREVVVTPNGAWGGE...GSLGCGIGYGYLHRIPTQ
Q22G20_TETTS/89-227..........EI------ELVVFNISDKS-----VRSVMLKPQMNWGGR...GLIGCEFGGGYLNQLPVI
Q2YDP4_BOVIN/69-205..........AL------KLMVYNSESDS-----CREVTVTPNAAWGGE...GSLGCGIGYGYLHRIPTQ
Q386P4_TRYB2/73-244REDRGLQTAGQL------LLLVYDSVNIE-----VKEVLV....DFGNDI.YAPLGMNLATGLLHLIPSP
Q4N0A2_THEPA/102-237..........EV------VLIVYNSVTET-----VRRALIVPRENWGGR...GTLGCDLAKGYIHRIPYV
Q4PFN7_USTMA/83-237..........AL------RLYVYNSDYDH-----TREVIIVPNREWGGE...GLLGCGVGYGLLHRIPKP
Q2HFQ7_CHAGB/78-211..........PL------RLYVYNNEYNV-----TREVTIQPSRDWGGE...GALGCVLGYGALHRLPAP
Q0CI81_ASPTN/81-215..........TL------VLWVYNSEFDV-----VREVELVPTRGWGGE...GALGAELGFGALHRLPVG
A5DW42_LODEL/191-326.....GEDNVPI------TLYVYNHDYDI-----LRPVTVNLSRSWGNGHNRGILGCDVGYGLIHRIPEV
A7EGH4_SCLS1/79-212..........PL------RLYVYNNEYNV-----TREITIHPSRDWGGD...GALGCTLGYGALHRLPAP
A6RJ89_BOTFB/62-195..........PL------RLYIYNNEYNV-----TREVTIHPSRDWGGD...GALGCTLGYGALHRLPAP

PF12812

B8MUN1_TALSN/264-341----------QE------FIQVMKTIPDR-----------------------------------------
NM111_PICST/379-456----------DT------LIEVMKMIPDC-----------------------------------------
NM111_PICGU/388-465----------DA------FVEVMKSIPDR-----------------------------------------
NM111_LODEL/379-456----------DE------FVEVMKQLPDC-----------------------------------------
B9W6Q0_CANDC/376-453----------DE------FVGVMKKIPDC-----------------------------------------
C5MEA8_CANTT/370-447----------DE------FVEAMKNVPDK-----------------------------------------
NM111_YEAS7/392-469----------DT------FIEIMKTIPDR-----------------------------------------
NM111_CANGA/374-451----------DA------FVEVMKTIPDK-----------------------------------------
NM111_ASHGO/372-449----------DT------FIEVMSTIPDC-----------------------------------------
NM111_KLULA/388-465----------DD------FIEVMKTIPDE-----------------------------------------
C4R214_PICPG/366-443----------DT------FIEVLKSIPDC-----------------------------------------
NM111_YARLI/360-439----------DT------FIKVIAAIPDG-----------------------------------------
B6JWG1_SCHJY/372-448----------DA------FIEVMKTLPDR-----------------------------------------
B2RIG1_PORG3/398-471----------AD------VSDIVR...EA-----------------------------------------
A6SSR9_BOTFB/12-90----------EA------FLKVVIQIPDN-----------------------------------------
B2WNT3_PYRTR/845-923----------SA------FLTEIKKIKDN-----------------------------------------
C4Y709_CLAL4/134-212----------ET------FVKITNDIPDN-----------------------------------------
NM111_KLULA/861-937----------DT------FLKVVKEIPDN-----------------------------------------
Q6CHS4_YARLI/371-442----------TE------LKEFFKNA.VH-----------------------------------------
B6QC43_PENMQ/337-413----------IE------GEKVLSKLKDR-----------------------------------------
B9H391_POPTR/179-254----------ED------VISVLSKL.CK-----------------------------------------
B8AHP7_ORYSI/375-450----------GD------LIACISKL.SR-----------------------------------------
A9RQ61_PHYPA/347-422----------DK------FISVFFKL.SR-----------------------------------------
A8JH35_CHLRE/368-444----------IT------FATVLRTLPHG-----------------------------------------
C1EGI7_MICSR/349-424----------DA------FANAYARL.EE-----------------------------------------
C1N456_MICPC/359-434----------DA------FAAAYAKL.KE-----------------------------------------
B6K3R7_SCHJY/399-475----------EA------LTKVILGLRDN-----------------------------------------
YH05_SCHPO/393-469----------DA------FIDVLVQLTDN-----------------------------------------
B8FNF0_DESAA/337-420----------DD------FIRLASALKHN-----------------------------------------
NM111_MAGO7/393-469----------ET------FIQVVKNIPDK-----------------------------------------
B2ASP9_PODAN/396-472----------DT------FIDVLKGIPDK-----------------------------------------
B2WNT3_PYRTR/372-451----------DT------FIQVMKKIPDR-----------------------------------------
C0NX23_AJECG/394-470----------DE------FIEVVKTIPDR-----------------------------------------
B6HPJ1_PENCW/491-567----------NE------FVEVMKNIPDR-----------------------------------------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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