Sequence alignment for CL0477

PF12950

B5ICQ9_ACIB4/763-920------KPFLVG.....KD.IKRY---------------RIEFR..................DRY-----------LILI
A0ZFG2_NODSP/1317-1435------KSLLRG.....EN.IGRY---------------IFDYK..................GEY-----------VWYV
A8UVR7_9AQUI/309-431------LPILNG.....RN.LKVG---------------KVIYE...................PL-----------TGYW
A8YXG9_LACH4/1021-1141------RPYIDG.....NN.VSRY---------------KLSWN..................GEY-----------IKYG
B1QKZ3_CLOBO/563-681------IKIYKG.....KN.IKKF---------------.ICYS..................YFY-----------YDFK
Q648L9_9ARCH/754-875------GKWLFG.....KD.ISRY---------------KQEWS..................GEW-----------LSYG
A1HPY6_9FIRM/461-579------PGLISG.....SQ.VNRY---------------CLKYQ..................GHW-----------LNID
Q1CU50_HELPH/387-501------IPIFRG.....SD.ILKD---------------RLKAP..................SQF-----------INAD
C5CH49_KOSOT/887-1032------KPYLTG.....KE.IKRY---------------SIEWK..................GKY-----------IILA
Q02YN3_LACLS/1013-1132------RKYLDG.....EN.VSRY---------------ALTWN..................GEW-----------LKYG
A6C2K5_9PLAN/396-510------LPVYKG.....AD.LQPG---------------SLREP..................STY-----------LPAD
B7A9M4_THEAQ/290-405------VPVLTG.....RN.LKPG---------------WVDYE..................KNH-----------SGLW
D5UBA4_BRAM5/209-336------KKVLFG.....KN.VHRY---------------SFEWT..................GFY-----------VNYD
Y3402_METJA/955-1077------LPYLEG......N.VYRY---------------ETKLKL.................KNY-----------VDFS
Q12U44_METBU/826-966------KKFIEG.....KD.LSRY---------------SISDR..................GLY-----------LDYL
B9DU79_STRU0/1021-1140------RPYLDG.....EN.VSRY---------------KLTWN..................GEY-----------VKYG
D0LRP5_HALO1/739-867------YPLYFG.....RDELRPF---------------RLLWR..................GRY-----------LRRA
A4CM25_ROBBH/762-881------VKEIKG.....KG.VHRY---------------SLNWT..................PSY-----------VKWG
B8JFL3_ANAD2/737-854------FPVLKG.....RD.IERY---------------AADPI...................RF-----------IHYD
D6XZV1_BACIE/524-637------EVVLKG.....KD.IYKY---------------NFVPG..................RNY-----------LEFL
B5YJE4_THEYD/332-454------LPLLNG.....RN.LKCN---------------EIIYE...................NL-----------TGYW
Q24XG1_DESHY/339-452------EVIYRG.....SD.VYKY---------------RCLPG..................QNF-----------IRFE
B0JLC9_MICAN/1017-1136------KKLLDG.....RN.INKY---------------SISWD..................GFY-----------LDYD
C4G3N9_ABIDE/491-604------EQILSG.....NN.IFKY---------------KFKNS..................SKY-----------IEFR
B3QU01_CHLT3/277-390------TPALTG.....RN.LSPG---------------KIDYE..................TNH-----------TNFW
C4GI54_9NEIS/774-890------KPLLRG.....SL.INRY---------------ENLWSE.................DSW-----------IEYG
A5N0R0_CLOK5/377-495------VEILKG.....EN.IKKF---------------QVLNN...................YY-----------YDFI
A6GW88_FLAPJ/761-878------LPLIDG.....AE.INRY---------------ELSTP..................NKY-----------FNFI
Q3IQE9_NATPD/931-1083------HPILRG.....NE.IKKY---------------DIGIPDEHVIYTNGVQIDDYPQAKSY-----------LSEY
C9L6V5_RUMHA/544-657------EMVLKG.....AD.ILKY---------------HINTT..................TNY-----------ITFE
D5UBA8_BRAM5/218-336------FPVIVG.....SD.INRY---------------TKTWG..................GKY-----------VYYV
Q647Q6_9ARCH/759-878------RPLLRG.....SL.IDKW---------------HIRWNN.................DYW-----------ISFG
Q72IB2_THET2/280-395------VPVLTG.....RN.LLPG---------------RIDYE..................TPY-----------SGLY
C0R107_BRAHW/240-364------KKLLKG.....KN.IKKY---------------KIEFD..................NNY-----------LIFE
Q6E3B7_9BACT/299-413------VPVLTG.....RN.LHAG---------------WIDYE..................TCY-----------SGYW
Q9APD5_GEOSE/455-582------KKYLGGKSFSKKNEVQKY---------------KIDWE..................GYY-----------INYD
C2LZV9_STAHO/856-975------KQLLEG.....KD.VKKY---------------YVEWNE.................KKW-----------ISYG
A8SWJ6_9FIRM/502-615------EGVITG.....AD.VYRY---------------RYGEP..................ERF-----------IASD
B0VG24_CLOAI/333-455------LPLLNG.....KN.LKCN---------------MINYN...................NL-----------TGYW
Q6UQ63_GEOSE/393-512------YPLLRG.....RN.IGYY---------------EILDT................CSGEF-----------VS..

PF01420

T1S1_METJA/225-407PEDWE.VFEIKD--------IFEV....KTGTTPSTKKSEYWEN------------------GEI...........NWIT
Q38085_9VIRU/6-167AREWK.DFSLEE--------LFTV.RGTKTTPLIILRKNNKKRE------------------KQL...........PYVT
T1SP_ECOLX/15-201EVEWL...PLSK--------VFNL....RNGYTPSKTKKEFWAN------------------GDI...........PWFR
O25209_HELPY/1-179MSEWQ.TFCLKD--------LGKI....VGGATPPTN..NPKNY------------------GNKI..........SWIT
Q7P6F9_FUSNV/5-165QKKWK.SFKISE--------IFRI....ESCKCGNA...SLLED------------------GDD...........LFYR
O25519_HELPY/109-276PKGVE.FRKLGE--------VCES...TNKKTLKISEVSEVKNK------------------GMY...........PVIN
T1SX_MYCGE/198-359QSQMH.EITLGE--------IFNF....KSGKYLKSE..ERLEE------------------GKF...........PYYG
O27024_METTH/222-387PVDWD.VVNLED--------VVEI...HDNKRIPLSEKERIKMK------------------GDY...........PYCG
Q0I2C2_HAES1/191-347DVEWK.EIFIEE--------VAEI....YSGKDIYE...RERTI------------------GNT...........PYIT
Q9ZJE8_HELPJ/211-381GLTWQ.HFKLGD--------LFEI......EKTLSFNKDALTQG------------------QDY...........DYIT
Q47280_ECOLX/200-383EVEWK...TLGE--------I.........GNFTYGYAAKAMDS------------------GDA...........RFVR
T1SX_MYCGE/10-171NINWT.KRTIDS--------LFDL....KKGEMLEKE..LITPE------------------GKY...........EYFN
O27024_METTH/15-193PVDWG.VSRVSE--------VFDV....FTGTTPSTKIDEFWDD------------------GDV...........VWVT
T1S_SALTY/7-187PEGWA.TSTINE--------MCNL......NPKLKLD..DDLDV------------------GFM...........PMAG
T1S_SALTY/225-410PSLWK.ISEIGQ--------FADV....KGGKRLPKGESLIAEN------------------TGF...........PYIR
T1S1_ECOLX/200-381EVEWK...TLGE--------IGKW....YGGGTPSKNKIEFWEN------------------GSI...........PWIS
O30379_MYCPL/91-256PSIFK.NYKLGQ--------ILNL....EKGKSKYNAKYVSQNI------------------GIY...........NLYS
O68172_9LACT/234-414ADDWE.ERKLGD--------IAPL....RGGYAFKSS..KFRKT------------------GV............PIVR
O52274_LACLL/215-398VDDWE.QRKLGE--------MLVN....LEAGVSVNS..SDYDT------------------GYF...........ILKT
T1S1_ECOLX/15-183EVEWL...PLGE--------ITKY....EQPTKYLVKAKDYHDT------------------YTI...........PVLT
T1SH_MYCPN/62-225NIPFE.TFQVKD--------ICEI....RRGRAITKAY.IRNNP------------------GEN...........PVYS
Q0I2C1_HAES1/15-176KVEWK.EFFLNE--------ICNI....NSGVRLTK...ANMNE------------------GKM...........PFIG
O54432_9LACT/215-394ADDWE.DRKLGE--------LASF....SKGNGYTKN..DLVEF------------------GD............PIIL
T1SA_MYCPN/147-310KEENK.YYKLGE--------IAQKVLVGGEKPADFSK..EKNEV------------------YKY...........PILS
Y1531_METJA/22-203PEDWE.VRELKD--------ILEV....IRNGLTAK...QNKDK------------------IGY...........PITR
T1SD_ECOLX/7-162PVDWK.TVELGE--------LIKL....STGKLDAN...AADND------------------GQY...........PFFT
T1SH_METJA/22-201PKDWD.VKKIKD--------IGEV....AGGSTPSTKI.KEYWG------------------GDI...........PWIT
O52188_STRTR/21-198TDDWE.ERKLGE--------LANI....VGGGTPSTSN.PEYWD------------------GDI...........DWYA
T1SB_MYCPN/179-342GEEYK.LFKLKD--------IAKKILVGGEKPSDFQK..EKDQV------------------YKY...........PILS
Q88AU8_PSESM/13-174YVTSV.DGRQAG--------VFHA....HKGRRLIA...AHRKA------------------GTT...........PFVG
Q1WR64_LACS1/1-159MVKFQ.KFRIGD--------LFTA....ESGDTDLKK..VDIEN------------------NGV...........PVIT
Q17V99_HELAH/11-175AVKWG.EFRLGD--------LFEA....SNGDFDIQKR.HINHR------------------GEF............VIT
T4BB_BACCO/4-164LIKYS.TFLISD--------LFDV....VIGKTIDGNKAQRNEN------------------GT............PYIT
Q88AU8_PSESM/192-354ELNYM.PMFITD--------VFES..MNAAGKWFDFAKACLSGK------------------PFA...........PYIA
O25479_HELPY/241-404PKGVE.FRKLGE--------VCEI...LDNRRIPIAK..NKRNP------------------GIY...........PYYG
T1SI_HAEIN/195-369IDEMNKVIELGD--------VGPV....RMCKRILKN..QTASS------------------GDI...........PFYK
Q4HPG5_CAMUP/917-1080PLKWK.SFKCEE--------LFSV....KSNPQLNKDSFSFSEN------------------APY...........PYFT
O68173_9LACT/224-383ADDWE.ERKLGD--------ITKI....STGKLDAN...AMVEN------------------GKY...........DFYT
O25479_HELPY/13-194PKGVE.FKTLEE--------VFEI....KNGYTPSKNNPEFWKN------------------GTI...........PWFR
Q0I2C2_HAES1/12-173DVKWK.EMYFID--------IFDN...IYIAKSTDQ...NKLKV------------------GNV...........PFIG
Q1WR64_LACS1/216-380NGKKV.NVSNDG--------LFNI...MSTKKKINAN..TITFG------------------GKY...........PYVA
T1SG_MYCPN/114-279NIPFE.TFQIRD--------ICEI....NRGREINEKY.LRENP------------------GEF...........PVYS
T1SI_HAEIN/16-176EVEWK...PLDE--------VANI...VNNARKPVKS..SLRVS------------------GNI...........PYYG
Q2HWD3_HELPX/11-179AIKWG.EFKLGD--------LFEI....YTGSLLSQ...EDLAK------------------GDI...........VRIS
Q1CRB1_HELPH/11-176AIKWG.EFSYET--------IYEL...QKTTKLLSKK..DCVEN------------------GKI...........PLFT
O34140_KLEPN/2-158GSKWK.ECELGD--------FIEL....KRGYDLPK...STRNE------------------GSI...........PIIS
T1S1_METJA/17-197PEDWE.IVELKD--------VCKK...IKAGGTPKTSVEEYYKN------------------GTI...........PFVK
T1SX_MYCPN/10-171NSNWT.KKTLGS--------LFEL....KKGEMLEKE..LLAPD------------------GKY...........EYFN
T1SB_ECOLX/22-192HDSWL.RISMDS--------VANI....TNGFAFKSSEFNNRKD------------------GV............PLIR
T1SH_HAEIN/1-179MSDWK.EYSLGD--------IS........RNISRRF..DFNAY------------------PNV...........VFIN
O28563_ARCFU/140-319PKEWE.VVRLGD--------VLEL........CQYGLSVPLKDK------------------GKY...........PVIR
O54432_9LACT/15-189TDDWE.ERKFGE--------VWKK...SSERNLNLEYSPKQVLS------------------VAQ...........MKLN
Y1218_METJA/22-191PEDWE.VVRIGD--------FIKY.IKGKKPAVMV....DEELE------------------GYY...........PYLS
T1S_SALPO/237-404GLAKRQGLNGNE--------ITIL......RLADFKD..AQRII------------------GNE...........RKIK
T4BB_BACCO/178-337DLSWS.QFKMDE--------IFSI....NSGVRLTK...ADMKP------------------GNI...........PFIG
T1SD_ECOLX/213-385PNNWS.WMRFDQ--------VADI.ASKLKSPLDYPNTIHLAPN------------------HIE...........SWTG
Q47280_ECOLX/15-181EVEWV...TLGS--------MADI....GTGSSNRQ...DESEN------------------GIY...........PFYV
O52274_LACLL/14-189TDDWE.KRKLKD--------FT...IKTGKKNSEGEDHPAYSVS------------------NKL...........GLVS
Q50356_MYCPL/215-384PSIFK.NYKLGE--------IAKI....LSGKTPSTAK.KELWK------------------KEI...........PFFG
O68169_9LACT/228-396ADDWE.ERKLGE--------VATF....LNGRAYKQD..ELLDS------------------GKY...........KVLR
Q4HPG5_CAMUP/705-862GGEWR.DIEIHK--------LFTP....QNGDFDIQK..LHLND------------------KGH...........QVVS
T1SH_HAEIN/266-440PRGWE.MKALSD--------LGQI....ICGKTPSKS..NKEFY------------------GDDV..........PFIK
Y1218_METJA/220-404PEDWE.VVKLKE--------VVDI....QSGKYFKYS..EFCEN------------------GVKCLKIDNVGFGKIFWE
T1SP_ECOLX/220-383EVEGK.RKTLGE--------IMKM....RAGQHISAH..NIIER------------------KEE...........SYIY
Q1JWR8_DESAC/162-320PTKWS.KFTIGS--------LFDV....IKGKRLTK...AQRRP------------------GMV...........RFIG

PF12950

B5ICQ9_ACIB4/763-920PSGWTNEHKKGRSAWEWFSSEYPAIAKHLAQFEEKAKKRWDKGEYWWELRPCDYYEEFEKPKIMF..P------------
A0ZFG2_NODSP/1317-1435PKIMTSHR...........................R.TARPGNKLRFE...........QPKVLI..R------------
A8UVR7_9AQUI/309-431IKPEHKTK...........................L.......RKFFD...........RPHIVVGLG------------
A8YXG9_LACH4/1021-1141.QNLAAMR...........................D.......PILFE...........GKRILV..R------------
B1QKZ3_CLOBO/563-681DKNIKGGT...........................K.....DLKKLKY...........KGKILV..R------------
Q648L9_9ARCH/754-875PWLA.APR...........................E.......ERFFI...........GPRLLF..R------------
A1HPY6_9FIRM/461-579PRLLYKGG...........................W......QAEVVR...........QRKILV..R------------
Q1CU50_HELPH/387-501LKDCQQVA...........................P.......LSLYQ..........AREKIVY..K------------
C5CH49_KOSOT/887-1032KDGIDIPH............DYPAIYEHLSQYKEALEKRWDKGKYWYNLRPCAYYSEFEKPKIVW..G------------
Q02YN3_LACLS/1013-1132.KHLARMR...........................D.......PRIFD...........NPRILV..R------------
A6C2K5_9PLAN/396-510FSLYHQVA...........................P.......RELYQ..........APEKLIY..R------------
B7A9M4_THEAQ/290-405MPKERAKE...........................L.......RDFYA...........TPHLVV..A------------
D5UBA4_BRAM5/209-336KSLIDKSK...........................KEYGNLCEEKYFE...........NPKILL..R------------
Y3402_METJA/955-1077KHKNNEKL...................................INLFM..........SPEKIFI..R------------
Q12U44_METBU/826-966PKMMYGPR...........................V.......PEFFE...........SPKLIT..R------------
B9DU79_STRU0/1021-1140.ENLAAPR...........................D.......KEIFE...........KPRILV..R------------
D0LRP5_HALO1/739-867AIPERNSK...........................ARYAGAGQRAWHE...........TPKLLL..R------------
A4CM25_ROBBH/762-881KWLMSPKS...................................EHYYK...........QHKILL..R------------
B8JFL3_ANAD2/737-854RERLDRPQ...........................T.......PEHFL..........VPEKLLI..R------------
D6XZV1_BACIE/524-637SNDFQQVA...........................P.......ERFYR..........AKEKLIY..R------------
B5YJE4_THEYD/332-454IKKADINK...........................L.......RGYFN...........IPHIVVGLG------------
Q24XG1_DESHY/339-452PKSFQQIA...........................P.......IDLYR..........AKEKLIY..R------------
B0JLC9_MICAN/1017-1136ITKIHSCK...........................R.......RDIFE..........TKEKLLF..R------------
C4G3N9_ABIDE/491-604PELYQQVA...........................P.......TEYYR..........AKEKLIY..R------------
B3QU01_CHLT3/277-390VKHSGAAT...........................L.......REFYG...........FAHIVI..G------------
C4GI54_9NEIS/774-890.EWLAAPR...........................D.......SKIFE..........AEEKIVV..R------------
A5N0R0_CLOK5/377-495PCNIKGGT...........................S.....DIKKLTT...........KNKIII..R------------
A6GW88_FLAPJ/761-878SENIKSGG...........................D.......FSIYE...........RLRIVI..R------------
Q3IQE9_NATPD/931-1083REKLANRS...........................D..GAFKGKEWFELNIPLSTEVLDSNKILC..P------------
C9L6V5_RUMHA/544-657PENFQQVA...........................P.......TEIYR..........AQEKLLY..R------------
D5UBA8_BRAM5/218-336PEKLHSNT...........................R.......ENIFK..........TKEKIII..R------------
Q647Q6_9ARCH/759-878.DWLAEPR...........................Y.......SANYD..........VPEKIVI..R------------
Q72IB2_THET2/280-395FPQAEVHR...........................L.......KPFYA...........FPRLVV..G------------
C0R107_BRAHW/240-364RKKLNRAR...........................P.......DEVWN..........SDKKIIT..Q------------
Q6E3B7_9BACT/299-413MAHERAAE...........................L.......RAFYG...........FPHLVV..A------------
Q9APD5_GEOSE/455-582QESLQKLG...........................N...KLPPLDNFE...........RSKIIF..C------------
C2LZV9_STAHO/856-975.EWLGNCR...........................K.......KEYFT...........KPRLLI..R------------
A8SWJ6_9FIRM/502-615ISLYQQAA...........................P.......ERIYR..........APEKLIY..R------------
B0VG24_CLOAI/333-455VKKQDVNK...........................I.......RMYFG...........YPHIVVGLG------------
Q6UQ63_GEOSE/393-512KDFIENSK...........................K.......SRYIK...........EKRIVC..Q------------

PF01420

T1S1_METJA/225-407PLDLSRLN--------------EKIYIGSSERKVTKIALEKCNLNLIP----------.KGSIIISTR........A...
Q38085_9VIRU/6-167TK.STYN.--------------..............GIDDFFSGFTEE----------.GNVITIDS.........A...
T1SP_ECOLX/15-201MDDIREN.--------------...GRILGSSLQKISSCAVKGGKLFP----------.ENSILISTS........A...
O25209_HELPY/1-179PK.DLSTL--------------QGRYIKKGSRSISRLGFKSCSCVLLP----------.KHAILFSSR........A...
Q7P6F9_FUSNV/5-165GAKKNDN.--------------...........GVIRRVKRIDSLVSK----------.GNCIMFICDGD......G...
O25519_HELPY/109-276SGRDLYG.--------------..................YYHDFNND----------.GENITIASRGE..........
T1SX_MYCGE/198-359AG.IDNT.--------------.................GFVAEPNTE----------.KDTISIISNG.......Y...
O27024_METTH/222-387AN......--------------..............GIIDYINDYIFN----------.GEFVLLAEDGGDY....S...
Q0I2C2_HAES1/191-347AT.ANNN.--------------............GIGYFVGNENKTME----------.SECISVNRN........G...
Q9ZJE8_HELPJ/211-381RT.SQNQ.--------------...........GVLQTTGFVNAENL.----------.NPPFTWSLG........L...
Q47280_ECOLX/200-383IT.DINK.--------------..DGKLSKENPMYVELNEENEKYTLD----------.KNDLLMARTG.......A...
T1SX_MYCGE/10-171GG.VKNS.--------------.................GRTDKFNTF----------.KNTISVIVG........G...
O27024_METTH/15-193PA.DMSNL--------------NGIMIADSERKVTVKALKRTNLNLIP----------.KLSILISTR........A...
T1S_SALTY/7-187VP.TTYL.--------------.....GKCNFETKKWSEVKKGFTQFQ----------.NDDVIFAKITPCFENGKA...
T1S_SALTY/225-410AGQLKNG.--------------..........TVLPEGQLYLEEYIQK----------SISRYTVSSGDLYITIVGA...
T1S1_ECOLX/200-381PKDMGRT.--------------...LVDSSEDYITEEAVLHSSTKLIP----------.ANSIAIVVR........S...
O30379_MYCPL/91-256SK.TRDQ.--------------..............GIFGKINSYDFN----------.GEYILITTHG.......A...
O68172_9LACT/234-414ISNILSS.--------------....GEVGGDFAYYDEQDKDDKYILP----------DKSAVLAMSG........A...
O52274_LACLL/215-398SAIKMGN.--------------...IDLLEVKSIVSEEVARAKTPLIK----------.NSIIISRMNTPELVGASGLVR
T1S1_ECOLX/15-183AG......--------------.........KTFILGYTNETHGIYQA----------SKAPVIIFDD............
T1SH_MYCPN/62-225AA.TTND.--------------..............GELGRIKDCDFD----------.GEYITWTTN........G...
Q0I2C1_HAES1/15-176AT.DSNN.--------------............GITSFISNTNKSLD----------.KNVLGVNYN........G...
O54432_9LACT/215-394YG.RLYT.--------------...........KYETVIEKVDTFVNK----------.KDKSIISGGSEVIVPASG...
T1SA_MYCPN/147-310NN.SKAE.--------------..............EFLVYSKTFRVE----------.EKSITVSAR........G...
Y1531_METJA/22-203IETISDS.--------------.......KIDITKLGYVEDIKQEDIA----------.KYRLIIGDILFSHINSEE...
T1SD_ECOLX/7-162CA......--------------..............ESVSQINSWAFD----------.TSAVLLAGN........G...
T1SH_METJA/22-201PK.DLANY--------------EYIYISRGERNITEKAVKECSLRIFP----------.KGTILLTSR........A...
O52188_STRTR/21-198PAEIGEQ.--------------..SYVSKSKKTITELGLKNSSARILP----------.VGTVLFTSR........A...
T1SB_MYCPN/179-342NS.RKAD.--------------..............DFLGYSKTFRIA----------.EKSITVSAR........G...
Q88AU8_PSESM/13-174AS.RVNN.--------------..............SITGFADTPALF----------PGGWITLIYNGD......G...
Q1WR64_LACS1/1-159SGVQNYG.--------------.............ILGLATRKAKVIP----------.KNTITVD..............
Q17V99_HELAH/11-175AGLSNNG.--------------.............VLGQSDIKAKVFE----------.SHTITID..............
T4BB_BACCO/4-164RK.ATRN.--------------...........GFEFMIDGEKEKLYS----------.GKLPVITIG........N...
Q88AU8_PSESM/192-354RSGGGNG.--------------............VGSFVPHQGFAPPN----------AGNAITIGV.............
O25479_HELPY/241-404AN......--------------..............GIQDYIDSYIFD----------.GDFVLVG..............
T1SI_HAEIN/195-369IG.TFGK.--------------.....KPDAYISNELFQEYKQKYSYP----------KKGDILISAS........G...
Q4HPG5_CAMUP/917-1080RT.CLNN.--------------...........GIAGYVEYLDEEHKI----------KGESIAVGML............
O68173_9LACT/224-383SGIKKYR.--------------...................IDVAAFE----------.GPSITIAGNG.......A...
O25479_HELPY/13-194MEDIREN.--------------...GRILKDSIQHITPKALKGKKLFP----------.KNSIIISTK........A...
Q0I2C2_HAES1/12-173RS.SINN.--------------...........GLQGEYFVEKEKINK----------.GNSLTISMV............
Q1WR64_LACS1/216-380RG.ENQN.--------------...........GIRGYINFDENYLNP----------.EKTISFGQ.............
T1SG_MYCPN/114-279SA.TTNG.--------------..............GLIGKINDYDFH----------.GEYVTWTTGG.......A...
T1SI_HAEIN/16-176AN......--------------..............NIQDYVEGYTHE----------.GEFVLIAED........G...
Q2HWD3_HELPX/11-179VKSDNNG.--------------...........VYGHFDTLKNKKARH----------FENFISVN..............
Q1CRB1_HELPH/11-176SD.SKNN.--------------...........GIVGYVNCKPSYKLK----------NNQCMVVFGD............
O34140_KLEPN/2-158SS......--------------..............GFTDFHDKPMVK----------.GPGVVTGRY........G...
T1S1_METJA/17-197IEDITNS.--------------.NKYLTNTKIKITEEGLNNSNAWIVP----------.KNSVLFAMY........G...
T1SX_MYCPN/10-171GG......--------------.............IKASGRTNEFNTF----------.KNTISIIIG........G...
T1SB_ECOLX/22-192IRDVLKG.--------------..........NTSTYYSGQIPEGYWV----------YPEDLIVGMD........G...
T1SH_HAEIN/1-179TGDVLNN.--------------...KFLHCEISNVKDLPGQAKKAIKK----------.GDILYSEIR........P...
O28563_ARCFU/140-319MDEIVNG.--------------...YVVTDIAKYADLDEETFKNFKLE----------.KGDVLFNRTNSLELV..G...
O54432_9LACT/15-189PS.NRNEQ--------------DDYMKTYNVLHKGDIAFEGNKSKSFA----------FGRFVLDDLQD.......G...
Y1218_METJA/22-191TE.YLRD.--------------.........GIASKFVKITNKEIIVN----------.ENDILLLWDG.......S...
T1S_SALPO/237-404LD.SKEE.--------------....................NKYSLE----------.NDDILVIRV........N...
T4BB_BACCO/178-337ATDSNNG.--------------.............ITEFTSSTNASFD----------.GNVLGVNYN........G...
T1SD_ECOLX/213-385KASGYQT.--------------...........ILEDGVTSAKHEFYT----------.GQIIYSKIR........P...
Q47280_ECOLX/15-181RS......--------------..............KNILKSDTFEFD----------.EVAIVIPGE........G...
O52274_LACLL/14-189QT.KQFD.--------------.........GSRLDFLDKTAYKFVNQ----------.GEFAYNPAR........I...
Q50356_MYCPL/215-384PG.DLDN.--------------..........MVPKRFITFNEKMIKR----------.SGTILFSSA........A...
O68169_9LACT/228-396VGNFYTN.--------------.........DSWYYSNMELGDKYYVD----------.KGDLVYTWS........A...
Q4HPG5_CAMUP/705-862AGLENNG.--------------.............VIGKTDIKARIFP----------.KNTLTCD..............
T1SH_HAEIN/266-440IP.DMHN.--------------.QVFITQTTDNLSVVGANYQSKKYIP----------.AKSICVSCI........A...
Y1218_METJA/220-404TVSFLPE.--------------..............DYLNKYPQLVLK----------.SGDIVLALNRPIIGGKI....
T1SP_ECOLX/220-383PC.FGGN.--------------..............GIRGYVKEKSHD----------.GEHLLIGRQG.......A...
Q1JWR8_DESAC/162-320ASEKNNG.--------------..............VTDLNDLLPTFP----------.GGQLTVAYN........G...

PF12950

B5ICQ9_ACIB4/763-920-DIAL.RMQ....ATYDDK----A-----F--YCVN--TAYIIP.......................VGDKYLL------
A0ZFG2_NODSP/1317-1435-DTGN.GLM....GTYEEL----N-----F--YVK.--DVLIISHQQKCT.................KTLKILV------
A8UVR7_9AQUI/309-431-FRGDGQIG....SAYDYR----V-----Y--PWMG--DVYHLLRKNTLLNANFD............LTEREVV------
A8YXG9_LACH4/1021-1141-QIPS.KKVYSIEAMVTNA----D-----L--IN..--DRNSMIIKDFNK.................IKPLALL------
B1QKZ3_CLOBO/563-681-KTGN.EII....AAYDEE----G-----I--IIEQ--SLYGIINLKQN..................FSHKYIL------
Q648L9_9ARCH/754-875-EVPG..VGKRIQATFVEE----R-----Y--YHGH--SITPFKPDGGNN.................LSLLYLL------
A1HPY6_9FIRM/461-579-QTGY.NII....ACIDEQ----G-----Y--YHLN--NIHSFVLKNNE..................VSLEYLL------
Q1CU50_HELPH/387-501-FISS.KLV....FFCDNE----Q-----R--LFLN--SANMFVLKENFP.................INANALK------
C5CH49_KOSOT/887-1032-NLAK.TAS....FAYDNF----G-----K--YVNA--PACIMP.......................TSEIWLL------
Q02YN3_LACLS/1013-1132-QIPT.YSTHAIEAMFIDE----E-----Y--IN..--DVNSAIITEIS..................MNPLYIL------
A6C2K5_9PLAN/396-510-FISS.RLV....FHYDTA----Q-----S--YFLN--SVNMLVTEPEFP.................ITGQQLC------
B7A9M4_THEAQ/290-405-HTKGTRVV....AAWDER----A-----Y--PWRE--EFHLLPKEGVR..................LDPSSLV------
D5UBA4_BRAM5/209-336-DISK.RPD....AIFDNE----K-----Y--YSVN--TLYSIQFVDGIE.................YNYLYLL------
Y3402_METJA/955-1077-RIVN.RQDRIM.ASYGNI----E-----G--VVKK--DLYVFVLKPDTP.................INYFYLL------
Q12U44_METBU/826-966-HVSG.KNDSLI.FTIDKM----G-----Y--YSDH--GLIMSTDYENLNSKNRTSFSDYTVDSKHNYQIELLL------
B9DU79_STRU0/1021-1140-QIPS.KSTYAVEAVYTDS----D-----V--IN..--DLNSMVITDIQ..................VNPFYLL------
D0LRP5_HALO1/739-867-RTGD.SVR....AAADLE----G-----R--YASN--NFFLVLARRDVGCA...............LNLDGLC------
A4CM25_ROBBH/762-881-QITGEYFF....AVLDME----Q-----Y--FADQ--SLYVCTYYNSKPK................TNLWFYL------
B8JFL3_ANAD2/737-854-RVGE.RLV....ATYDDQ----Q-----L--FCVH--TLYTVRPKSPG..................VRLKMLL------
D6XZV1_BACIE/524-637-FINK.KLV....FAYDNN----Q-----T--LTLN--SANILIPKIEG..................YDIKYVM------
B5YJE4_THEYD/332-454-FRENGRVA....AAYDEK----C-----Y--PWMG--DVYHLIRKTNLFNLNFD............MSEQEVV------
Q24XG1_DESHY/339-452-FIGG.SLV....FAYDNS----Q-----T--LTLN--SANIVIPKLEG..................LNIKYIL------
B0JLC9_MICAN/1017-1136-RVSR.TLI....FTYDNS----Q-----Y--YALN--TLVVVNLKKGIN.................FDIKFLL------
C4G3N9_ABIDE/491-604-FISN.RIV....MAYDNK----S-----T--LTLN--SCNVLIPQIPG..................LYTKYVM------
B3QU01_CHLT3/277-390-HTKGARVV....AAYDEK----C-----Y--PWRE--EFHLVPKVN....................VHERQIV------
C4GI54_9NEIS/774-890-QTGD.RII....ATVIGK----D-----I--ICRN--NLHIVIAQQ....................RNHKFLL------
A5N0R0_CLOK5/377-495-KTGK.HLI....SALDTK----G-----S--IIEQ--SLYGIICLDER..................FSPYYIL------
A6GW88_FLAPJ/761-878-QIGQ.TPI....IGICEP----K-----I--LTSN--TLYNLYMKTED..................YSLKYVF------
Q3IQE9_NATPD/931-1083-DISE.ENN....FAYDTE----A-----T--HILN--TAYLLRATDDSD.................YSLKYLT------
C9L6V5_RUMHA/544-657-FISN.QFV....FAYDDK----Q-----T--LSLN--SCNIVIPKIPG..................IKIKYVL------
D5UBA8_BRAM5/218-336-QTSN.KII....GTYDDE----S-----F--FTLA--STFIIKQFNEE..................IDYKALL------
Q647Q6_9ARCH/759-878-QTGD.SLI....ATLDRK----Q-----F--VVRD--NLYTIVPRSND..................IKPPYIL------
Q72IB2_THET2/280-395-HTRHYRVV....AAWDGR----A-----Y--PWRE--EFHLLPKEGVR..................VDWEGVV------
C0R107_BRAHW/240-364-RISG.GLHPII.AALDTE----N-----Y--YSFA--STNLIIIKDEFKDV...............YSYELIC------
Q6E3B7_9BACT/299-413-HTKGTRVV....CAMDER----C-----Y--PWRE--EFHLTPKQVG...................IDQHTVM------
Q9APD5_GEOSE/455-582-QHAR.VIT....ATFDEK----G-----E--WVTK--DVFPIAFESSKLPDSP.............FSLKYFT------
C2LZV9_STAHO/856-975-EITSPTIY....CAYTEK----E-----F--YNTV--SIINVINKTEE..................ISLFYIL------
A8SWJ6_9FIRM/502-615-FINR.QLV....FAYDDR----R-----H--LTLN--SCNVVIPRVAG..................LDMKYIM------
B0VG24_CLOAI/333-455-FRENGKVA....AAFDEK----C-----Y--PWMG--DVYHLVRENSLFNCHFD............LETEEVV------
Q6UQ63_GEOSE/393-512-QVVNMKKERRVTFALVEE----N-----Y--VLGN--SCNFISVMDNDYN................IDLYAIL------

PF01420

T1S1_METJA/225-407.PVGY--------VAVLTV....E.....S..TFNQ..GCKGLFQKNNDSVN...TE----------FYAYYLK....FK
Q38085_9VIRU/6-167.TDGY--------VFYQLN....N.....F..SASD..HVEKLIP...KFKL...NK----------YIALFLV....NC
T1SP_ECOLX/15-201.TIGE--------HALITV....P.....H..LANQ..RFTCLALKE.SYADCFDIK----------FLFYYCF...SLA
O25209_HELPY/1-179.PIGY--------VAIAEK....R.....L..CTNQ..GFKSIIP...NKKI....Y----------FEFLYYL....LK
Q7P6F9_FUSNV/5-165.SCGY--------TNYISD....D........FIGS..TTTSVGY...NENL...NV----------YIGTFIT....TI
O25519_HELPY/109-276.YAGF--------INYFNE....K.....F..FAGG..LCYPYKVKDTNELL...TK----------FLYFYLK...TNE
T1SX_MYCGE/198-359.SLGN--------IRYHEI....P.....W..FNGT..GSIALEPMNNEIYV....P----------FFYCALK....YL
O27024_METTH/222-387.SFGS--------SAYIMN...GK.....F..WVNN..HAHVIEALP.SKIT.....----------NRFLLHI....LI
Q0I2C2_HAES1/191-347.SVGY--------AFYHCY....E.....A..LYGN..DTRKLKPFIK.......NK----------YTALFIT....HA
Q9ZJE8_HELPJ/211-381.LQMD--------FFYRKK....S.....W..YAGQ..FMRKITPK..TEIKNKINS----------RIAHYFT....TL
Q47280_ECOLX/200-383.TFGK--------TMIFEE....D........YPAV..YAGFLIKLNLNETI...IN----------AKYYWHFAQSDFF
T1SX_MYCGE/10-171.SCGY--------VRLADK....N.....F..FCGQ..SNCTLNLLDPLELD...LK----------FAYYALK....SQ
O27024_METTH/15-193.PVGY--------VALNTV....E.....C..VFNQ..GCKALVPK..SHVD...TR----------YFAYYLL....IN
T1S_SALTY/7-187.VVIK--------EFPNGY....G........AGST..EYYVLRSI..NGLI....N----------PHWLFAL....VK
T1S_SALTY/225-410.CIGD--------AGIIPD..........V..YNNA..NLTENAAKICNLNENIFNR----------FLSLWLR..SSYL
T1S1_ECOLX/200-381.SILD--------KVLPSALIKVP.....A..TLNQ..DMKAVIPHE.NILV....K----------YIYHMIGSRGSDI
O30379_MYCPL/91-256.YAGT--------VKYVNE....K.....F..STTS..NCFILKVNE.NIVK...TK----------FLSYLLL....LQ
O68172_9LACT/234-414.TTGK--------VSILSQTDYDK.....V..YQNQ..RVGYFQSV.........DY----------IDYGFIS....TI
O52274_LACLL/215-398ESIDN--------IFLPDR..........L..WQGQ..VAGNFSP...EWLI.....----------.QSINIA....AN
T1S1_ECOLX/15-183.FTTA--------NKWVDF....D........FKAKSSAMKMVTSCDDNKTL...LK----------YVYYWLN......
T1SH_MYCPN/62-225.YAGV--------VFYRNG....K.....F..NASQ..DCGVLKVKNKKICT....K----------FLSFLLK......
Q0I2C1_HAES1/15-176.SVVE--------NFYHPY....E.....C..IFSD..DVKRVSFKDEQGQN....K----------RCYMFLK....QM
O54432_9LACT/215-394.ESSE--------DISRAS....VVGKSGI..ILGG..DLNIIKPVN.........Y----------IDSIFLA....LT
T1SA_MYCPN/147-310.TIGA--------VFYRDF....A.....Y..LPAV..SLICFVPKE.........E----------FDIRFLF....HA
Y1531_METJA/22-203.HIGK--------VAIYEG..........KPEFLLH..GMNLLLLRPNKNKI...EP----------YYLLYLL....RH
T1SD_ECOLX/7-162.SFSI--------KKYTGK..........F..NAYQ..RTYVIEPILIK......TE----------FLYWLLR....GN
T1SH_METJA/22-201.PIGY--------VAIAKN....P.....L..TTNQ..GFRNIIPK..DGVV...SE----------YLYYLFK..TKTM
O52188_STRTR/21-198.GIGN--------TAILAK....E.....A..TTNQ..GFQSIVPDQ........NK----------LDSYFIF....SR
T1SB_MYCPN/179-342.TIGA--------VFYRDF....S.....Y..LPAV..SLICFIPKP.........E----------FNINFLF....HA
Q88AU8_PSESM/13-174.GTGH--------AKYQPA....P.....F..NASD..DVIALEPIS.KQAT....E----------PALLLIA....SM
Q1WR64_LACS1/1-159.MFGN--------VYFRDF....E.....Y..KMVT..HARVFSLIP.KQNI...TR----------SIGLYFQ....TC
Q17V99_HELAH/11-175.MFGC--------AFYRSF....P.....Y..KMVT..HARVFSLKP.KFEI...SH----------KIGLFLS....TL
T4BB_BACCO/4-164.ETSK--------PFVQEF....H.....F..FTGT..KVNICIP...KLDL...NR----------NHLLYIT....TM
Q88AU8_PSESM/192-354.STST--------VFYQPV....P.....F..YTSK..EIQVLR....HHKL...TA----------DSGLILV....AL
O25479_HELPY/241-404.EDGS--------VINKDNTPVVNWASGKI..WVNN..HAHVLQTKN.ELKL....K----------FLYFYLQ....TI
T1SI_HAEIN/195-369.TIGR--------TVIFDG..........ENSYFQD..SNIVWID...NDETLVLNK----------YLYHFY.....KI
Q4HPG5_CAMUP/917-1080..GMQ--------FFYMQK....D.....F..YAGQ..FTKTLYP...KFSG..LNT----------TIAHFFI....TW
O68173_9LACT/224-383.TVGY--------MHLADN....K.....F..NAYQ..RTYVLQ....EFLV....D----------RSFIFSE.IGNKL
O25479_HELPY/13-194.TIGE--------HALLIV....D........SLAN..QQFTFLSKKANCDLALDMK----------FFFYQCF....LL
Q0I2C2_HAES1/12-173.GEPK--------CFYQKY....S.....F..TCSQ..NILVLQN...NEFI...NI----------TNSKFLI....PI
Q1WR64_LACS1/216-380.DTAT--------MFYQPK....A.....Y..FTGD..KIQVFSLNNKYGKL...NE----------NIALYLI....AA
T1SG_MYCPN/114-279.HAGN--------VFYRNE....K.....F..SCSQ..NCGLLEVKN.KNKF....S----------SKFLCFA....LK
T1SI_HAEIN/16-176.SASL--------ENYSIQWAVGK.....F..WANN..HVHVVNGK..EKLN...NR----------FLYHYLT....NM
Q2HWD3_HELPX/11-179.FFGN--------CFYHPY.............LASV..EMKVHVLKLKNHTL...TK----------RIGLFLA....NQ
Q1CRB1_HELPH/11-176.HTRT--------FNIAKN....D.....F..CIAD..NVKVLKPIK.DFSI.....----------RVLLFIN....TM
O34140_KLEPN/2-158.TIGE--------VFYSEE....D.....F..WPLN..TTLYVVDFKGNDPL.....----------FVYYLLQ....TI
T1S1_METJA/17-197.SIGE--------TAINKI....E.....V..ATNQ..AILGIIPKD.NILE...SE----------FLYYILA....KN
T1SX_MYCPN/10-171.SCGY--------VRLADK....D.....Y..FCGQ..SSCTLTVLDPLEID...LK----------FAYYALK....SQ
T1SB_ECOLX/22-192.DFNA--------TIWCSE....P.....A..LLNQ..RVCKIEVQEDKYNK....R----------FFYHALP....GY
T1SH_HAEIN/1-179.GNGR--------YLFVDN....D..LDNY..VVST..KFMVIEP...NANI...VL----------PEFLFLL....LI
O28563_ARCFU/140-319.RTGI--------FLLDGY..........Y..VFAS..YLIRLRPKH.EILH...PH----------FLTFYLI....FS
O54432_9LACT/15-189.IVSH--------VFYVYR....P........ICKM..DTDFMIVYINNESV.....----------MKYLLVK....AT
Y1218_METJA/22-191.NAGE--------IFLGKK....G........ILSS..TMVKLEQ...KNKI...MD----------DLYLFYS....LK
T1S_SALPO/237-404.GSAD--------LAGRFI....E.....Y..KSNG..DIEGFCDHF.IRLRLDSNK----------IMSRFLT....YI
T4BB_BACCO/178-337.SVVE--------NFYHPY....K.....A..VFSD..DVKRLKLK..NYPN...NK----------HVLLFMK....VV
T1SD_ECOLX/213-385.YLCK--------VTIATF....D.....G..MCSA..DMYPINSKIDTHFL.....----------FRWMLTN....TF
Q47280_ECOLX/15-181.GIGD--------IFHYVE...GK.....Y..ALHQ..RAYRIRITT.NAVD...TK----------FLYYFMS....SS
O52274_LACLL/14-189.NVGS--------IAFNDL..........GKTVIVS..SLYVVLKIS.DKLD...NE----------YILQFIK..SIKF
Q50356_MYCPL/215-384.TIGK--------VGILDN....L.....S..WFNQ..QITSIEANN.NYVM...DK----------FLFFLLK....KI
O68169_9LACT/228-396.TFGP--------HIWSGE.............KVIY..HYHIWKVELSKFLD...RN----------FTLQLLE....AD
Q4HPG5_CAMUP/705-862.MFGN--------VFYRDF....E.....Y..KMVT..HARVMCLHP.LFEL...NK----------KTGLYIA....ST
T1SH_HAEIN/266-440.TVGL--------VSMTSK....P.....S..HTNQ..QINSIIP...DDEQ....S----------CEFLYLS....LK
Y1218_METJA/220-404.KIGI--------LKDIDE....P.....A..ILYQ..RVGRFIFKSEKIDK....Q----------FLFYLLM..SEYF
T1SP_ECOLX/220-383.LCGN--------VQRMKG....Q.....F..YATE..HAVVVSVMP.GINI....D----------WAFHMLT....AM
Q1JWR8_DESAC/162-320.SVGW--------AFYQDK....P.....F..FACD..DINVLDP...KEPI...SK----------WALLFVA....TV

PF12950

B5ICQ9_ACIB4/763-920--------------------------GILNSKMVH.FYYANITS------------------TI..RGGYMRFIR-----
A0ZFG2_NODSP/1317-1435--------------------------SILNSSLMK.FYYETSFP------------------TL.......HVQR-----
A8UVR7_9AQUI/309-431--------------------------EFLNSEIIK.RYVKDIF.------------------....REITYHLSI-----
A8YXG9_LACH4/1021-1141--------------------------GILNSKIETLWFLMHFDK------------------FQ..RRLFPQFKV-----
B1QKZ3_CLOBO/563-681--------------------------GILNSQLIS.WYYKKYLI------------------TN..KESTPQLKK-----
Q648L9_9ARCH/754-875--------------------------GLSNSKLIT.WYGDLILP------------------NF.GKDTFPKLNP-----
A1HPY6_9FIRM/461-579--------------------------LLLNSRLMS.FYYHATTL------------------EF..GRPMAQTDI-----
Q1CU50_HELPH/387-501--------------------------ELLNSDLMQ.FIFESLFK------------------TH.......KILR-----
C5CH49_KOSOT/887-1032--------------------------TLLNSKVID.FFLRKLAI------------------ER..RGGFVEQKP-----
Q02YN3_LACLS/1013-1132--------------------------GVINSKLITLWFMMNFDK------------------FQ..RRVFPQFKV-----
A6C2K5_9PLAN/396-510--------------------------QILNSRVMN.WLFQSIFE------------------TH.......KVLR-----
B7A9M4_THEAQ/290-405--------------------------QWLNSEAMQ.KHVRTLY.------------------....RDFVPHLTL-----
D5UBA4_BRAM5/209-336--------------------------GILNSNLIA.FYFRNKFE------------------EAHVSGGYLRFKK-----
Y3402_METJA/955-1077--------------------------GILNSELISYIYIGKSAI------------------AL..KDDFRQTTL-----
Q12U44_METBU/826-966--------------------------GILNSKLMS.FFYANVYA------------------TGSLQGSYSHVYP-----
B9DU79_STRU0/1021-1140--------------------------GILNSRLISLWFFMKFDK------------------FQ..RRLFPQFKV-----
D0LRP5_HALO1/739-867--------------------------ALLNSALMT.EFFRTIEP------------------RR..GRAFAELKI-----
A4CM25_ROBBH/762-881--------------------------ALLNSRLYG.FYFRKYYS------------------EE..DDLFPKIKV-----
B8JFL3_ANAD2/737-854--------------------------GFLNSRLMT.LLFRTANP------------------QK..GKVFPEVRI-----
D6XZV1_BACIE/524-637--------------------------AILNSRVAQ.FYHTYMFS------------------PL.......KVLK-----
B5YJE4_THEYD/332-454--------------------------EYLNSDYVK.RYVKDIY.------------------....REITYHLSI-----
Q24XG1_DESHY/339-452--------------------------AILNSRVIQ.YYYSKCFR------------------SV.......KVLR-----
B0JLC9_MICAN/1017-1136--------------------------GIMNSSLMN.YIYNNKFK------------------ST..KTVFSEIQT-----
C4G3N9_ABIDE/491-604--------------------------GILNSRIVQ.FYFRKMFD------------------SV.......KVLR-----
B3QU01_CHLT3/277-390--------------------------EYLNSEQVQ.VHIKTLY.------------------....RDLIPHLTR-----
C4GI54_9NEIS/774-890--------------------------GVLNSKLAN.FCYYQINP------------------ER..GESLAEVKK-----
A5N0R0_CLOK5/377-495--------------------------GLLNSKLIQ.WYYLNFLI------------------TN..ANSTPQIKK-----
A6GW88_FLAPJ/761-878--------------------------SVLNSKIIK.MYWLSNYS------------------DS..KQLFPKIKG-----
Q3IQE9_NATPD/931-1083--------------------------GLLNSNVLE.FYVKMISP------------------PL..RGGYHRYIT-----
C9L6V5_RUMHA/544-657--------------------------AILNSRIAQ.FIYKKEFN------------------SV.......KILR-----
D5UBA8_BRAM5/218-336--------------------------GILNSKLFY.YLYVNLNN------------------EQ..GRVLPQIKK-----
Q647Q6_9ARCH/759-878--------------------------GLLNSRLLNWYYQKIINP------------------EQ..GEALAQVKR-----
Q72IB2_THET2/280-395--------------------------AYLNGPLAQ.AYYRGLY.------------------....REVVPHLTR-----
C0R107_BRAHW/240-364--------------------------ALLNSKLIN.FYYVKNFT------------------NA..STLTVNISK-----
Q6E3B7_9BACT/299-413--------------------------GWLNSAPVQ.RYMQSLY.------------------....RDFVPHLTL-----
Q9APD5_GEOSE/455-582--------------------------GLLNSSFYS.FLYGIIYK------------------GI.......QISA-----
C2LZV9_STAHO/856-975--------------------------AIINSKVFN.FYHRKNSP------------------KS.NKGIYPKILV-----
A8SWJ6_9FIRM/502-615--------------------------AVLNSRVAQ.YIYEKRYN------------------AV.......KVLR-----
B0VG24_CLOAI/333-455--------------------------AYLNSDYIK.KYVKDTY.------------------....REITYHLSI-----
Q6UQ63_GEOSE/393-512--------------------------GLFNTSIIN.WLFKLTSS------------------NN.......HVNN-----

PF01420

T1S1_METJA/225-407KN......LLENL.......SGGSTFKELSKSMLE..NFKIPLP.......PL.EE......QKQIAKILSSVDK.SIEL
Q38085_9VIRU/6-167IK......KATKC.......KYGYGY.KFSQTRIK..RQKIMLP.......AS.N.......NQPDFQFMERYIK...EK
T1SP_ECOLX/15-201E.......WCRKN.......TTMSSFASVDMDGFK..KFLIPRP.......CPDNPEKSLAIQSEIVRILDKFSALTAEL
O25209_HELPY/1-179YH......KNNFI.......NMGEGTTIKGIYNIALGLFKVKIP.......PTYYE......QQKIARTLSILDQ...KI
Q7P6F9_FUSNV/5-165LD......MH..........KYKYSHSRKYRNSLL..NEILILP.......IN.ND......GIPDWKWIEEYMK...SL
O25519_HELPY/109-276IQ......IMENL.......VFRGSIPALNKADIE..TLTIPIP.......PL.EI......QQEIVKILDQFSALTTDL
T1SX_MYCGE/198-359QK......DIKER.......MKSDDSPFLSLKLAG..EIKVPYV.......KSFQL......QRKAGKIVFLLDQ...KL
O27024_METTH/222-387YL......DLTHY.......VVGSTRKKLNQGIMR..KIKIPLP.......PL.EE......QKRISEILQDVDR.RLEL
Q0I2C2_HAES1/191-347I.......TSQKD.......KYGYGY.KMGTGRLK..RQKIMLP.......VS.D.......GEVNYKYMENFIK...NI
Q9ZJE8_HELPJ/211-381LN......ALKR........PLLSVLVRDIDKTFR..EQKIQLP.......LK.PTAKTQSLDGIDFDFMHTLIN...AL
Q47280_ECOLX/200-383WE......QANKL.......VSGGGQPQFNANALK..QVRVPIPYPSHPQKSL.DE......QGRIVDILDKFDAIAASI
T1SX_MYCGE/10-171QE......RIEAL.......AFGTTIQNIRISDLK..ELEIPFT.......SNKNE......QHAIANTLSVFDE...RL
O27024_METTH/15-193KK......RLQDL.......SGGSTFKELNKKTLE..KIYLPVP.......PL.EE......QKRISEILQDVDG...AI
T1S_SALTY/7-187TK......DFLTNGALNM..SGSVGHKRVTKEFLE..NYGVPVP.......PL.AE......QKVIAEKLDTLLA.QVDS
T1S_SALTY/225-410QD......IINSE.......IKSGAQGKLALARIK..SLPLILP.......PL.QE......QHEIVRRVEQLFAYADTI
T1S1_ECOLX/200-381LR......AAK.........KTGGSVASIDSKKLF..SFKIPVP.......NI.NE......QQRIVEILDKFDTLTNSI
O30379_MYCPL/91-256EK......TFNDM.......AIGSAYGYLKNYNIN..DFEVNLP.......NL.KI......QSAILGIIEPLHK...KI
O68172_9LACT/234-414VRSELFMMQLESV.......LVSGAQPNVSSKEID..SFNFMIP.......ILVQE......QQKIGSFFKQLDD.TIAL
O52274_LACLL/215-398IK......KIRDLAT.....GTSGSMKNISKKSML..DLIINVP.......TL.EE......QQKIGSFFKQLDD.VIAL
T1S1_ECOLX/15-183........TLPSE.......FAEGDHKRQWISNYS..QKKIPIP.......CPDNPEKSLAIQSEIVRILDKFTALTAEL
T1SH_MYCPN/62-225IE......APKFV.......HNLASRPKLSQKVMA..EIELSFP.......PL.EI......QEKIADILFAFEKLCNDL
Q0I2C1_HAES1/15-176I.......LQQKE.......KYRYAY.KFNGDRMA..RQKVMMP.......VD.KL......GNIDFKFMNRYIA...SK
O54432_9LACT/215-394ISNGSQQKEMSKR.......AQGKSVVHLHNSDLK..QVNILYP.......KL.GE......QQKIGSFFKQLDN.TIVL
T1SA_MYCPN/147-310LR......AIKFK.......KQGSATGQLTVAQFK..EYGIHVP.......SL.KK......QKEIAAILDPLYSFFTDL
Y1531_METJA/22-203FK......QKNIFKYIA...KRAVNQSSINQTQLK..HLKIPLP.......PL.EE......QKQIAKILSDFDN....L
T1SD_ECOLX/7-162IK......KITEN.......GRGSTIPYIRKGDIT..DISVALP.......SP.SE......QTLIAEKLDTLLA.QVES
T1SH_METJA/22-201SE......YLKDI.......SGGSTFPELKGSTLK..EVEIPYP.......SP.EE......QQKIATVLSYFDD...LI
O52188_STRTR/21-198TN......ELKRYGEVT...GAGSTFVEVSGKQMS..KMSIMVP.......EL.SE......QQKIGSFFKQLDE.TITL
T1SB_MYCPN/179-342LK......ATKFH.......KQGSGTGQLTMAQFK..EYQVYIP.......SL.KK......QQEIAATLDPLYY.IFAN
Q88AU8_PSESM/13-174LT......LQCVP.......KFGFGY.KLTLHRLD..RQKIMIP.......VLTNADGE...QVVNWSGLTRHGK.....
Q1WR64_LACS1/1-159LS......KHKR........KFSYDN.MCVFTKLE..NETIELP.......IA.DA......GKLDVEFIENYIR...QL
Q17V99_HELAH/11-175FF......GYPK........KFGYEN.MCSWAKIK..NDKVILP.......LK.PTANTKTLDSIDFNFMENFIA...EL
T4BB_BACCO/4-164IE......NATKM........FSYSY.TINSTRLK..SLKILLP.......IK.G.......EEPDWDYMNTYIS...KI
Q88AU8_PSESM/192-354LR......EQMG........KFQWGN.GASLERLK..ATRIMVP.......AMVGADGE...DVVDWDGLSRYGR.....
O25479_HELPY/241-404........DVSY........CVAGTPPKINQENLK..KIAIPIP.......PL.EI......QQEIVKILDQFSILTTDL
T1SI_HAEIN/195-369AK......WGIAE.........GGTIQRLYNDNLK..KVKISIP.......PL.KE......QHRIVSILDKFETLTNSI
Q4HPG5_CAMUP/917-1080LN......KNQKI........FQGVLVRDFEKTFN..KTEILLP.......IL.DS......NNIDFNFIESFIK...AI
O68173_9LACT/224-383PK......KIKQE.......ARTGNIPYIVMDMLT..ELKLSIP.......QNNSE......QQKIGSFFKQLDD.TIAL
O25479_HELPY/13-194GE......WCKNN.......INVSGFASVDMTAFK..KYKFPIP.......PL.EI......QQEIVKILDAFTELNTEL
Q0I2C2_HAES1/12-173IDN.....YLKAK.......GYGYGY.PVGKERVL..RNKLLLP.......VD.EN......NQINWHFMEEYIK...ER
Q1WR64_LACS1/216-380VK......RALV........NFAWGQSSFALEAIS..ELNITLP.......ID.NN......NQLHLDYMENYIR...AI
T1SG_MYCPN/114-279LQ......SKKFV.......NYASAIPVLTIKRIA..EIELSFP.......PL.EI......QEKIADILFAFEKLCNDL
T1SI_HAEIN/16-176........NFIPF.......LAGKERAKLTKAKLQ..QIPIPIP.......PL.SV......QTEIVKILDALTALTSEL
Q2HWD3_HELPX/11-179LN......KCFYG.......QFTYGT.QLSSSKLKHNNFKIQLP.......LK.PTTKTQTPEDIDFDFTEKFIA...EL
Q1CRB1_HELPH/11-176WG......KKII........DKGYAR.HWSLAK....TAKIQLP.......LK.PTAKTQTLEDIDFDFMEKFIA...EL
O34140_KLEPN/2-158........SYADY.......TDKAAVPGVNRNHLH..KAKVKVP.......IYLDI......QQKVAAQLYQLEK.RVTL
T1S1_METJA/17-197KN......YYSKL.......GMQTTQKNLNAQIVK..SFKIPLP.......PL.EE......QKQIAKILTKIDE.GIEI
T1SX_MYCPN/10-171EE......KITSL.......ASGTTIKNIRLSDLK..DLPIPLV.......KSIQD......QRTIAHALSVFDL...RI
T1SB_ECOLX/22-192LS......AINAN.......TSSVTVKHLSSRTLQ..DTLLPLP.......PL.AE......QKIIAEKLDTLLA.QVDS
T1SH_HAEIN/1-179SNETTEYFKMIAE.......SRSGTFPQITFDSVS..SLSLNIP.......DK.ET......QQKILDIITPLDD.KIEL
O28563_ARCFU/140-319QS......RLKQLA......TVAVHQANINATNLK..KFKIPLP.......PL.PE......QQKIAEILSTVDK.KLEL
O54432_9LACT/15-189TK......TLMMT..............TLNTKDIV..KPKLNLP.......SL.EE......QQKIGSFFKQLDA.TIAL
Y1218_METJA/22-191LKES....FLKSQ.......TKGTGIPHVDKKIFE..NIKIPLP.......PL.EE......QKQIAKILSDFDN.LIGT
T1S_SALPO/237-404AN......EGEGRFYLRNSLSTSAGQNTINQTSIK..GLSFLLP.......PL.KE......QAEIVRRVEQLFAYADTI
T4BB_BACCO/178-337I.......LQQKV.......KYAYGY.KFNATRMK..EQIILLP.......TK.AD......GTPDYEFMEQYMM...RM
T1SD_ECOLX/213-385TD......WASNA.......ESRTVLPKINQKDLS..EIPVPTP.......PL.PE......QHEIVRRVEQLFAYADTI
Q47280_ECOLX/15-181FKQ.....YILTK.......SVGATAISIRKPMLE..GFKVPIP.......SPDNPEKSLAIQSEIVRILDTFTALTAEL
O52274_LACLL/14-189IE......EVKRN.......TEGSVREYLFFDNFK..NIKFPYI.......KNLEE......QQKIGSFFKQLDN.TITL
Q50356_MYCPL/215-384SS......KIKFEN......SSGTIFPTIKKKYFE..NFTLEIP.......NL.KT......QSAILGIIEPLHK.KINL
O68169_9LACT/228-396KA......RLLSS.......TNGSTMIHVTKGDME..SKIVSIP.......NI.DE......QKQIGSFFKQLDN.TITL
Q4HPG5_CAMUP/705-862MN......YFKL........LFCFAD.MATWSKIS..NLKLSLP.......VL.N.......EQIAFDYMESYIK...AL
T1SH_HAEIN/266-440QP......SMTKYLKDLA..SGGTATLNLNTSTFS..KIEIITP..........S.......KEIIYIFQKKVVS...IF
Y1218_METJA/220-404KK......ELSKL.......LIGTDQPYIRTPVLL..NIKIPLP.......HL.EE......QKAMAERLKSIDN.LIEI
T1SP_ECOLX/220-383........NLNQY.......ASKSAQPGLAVGKLQ..ELKLFVP.......SI.ER......QIYIAAILDKFDTLTNSI
Q1JWR8_DESAC/162-320L.......KHERT.......RYTYGY.KWTKERMT..MTPIRLP.......AT.DS......GKPDWPYMESYMR...GL

PF12950

B5ICQ9_ACIB4/763-920---QYLEMIPI
A0ZFG2_NODSP/1317-1435---NELAVLPM
A8UVR7_9AQUI/309-431---TQLNVLPM
A8YXG9_LACH4/1021-1141---NELAQFPV
B1QKZ3_CLOBO/563-681---YRLNKIPI
Q648L9_9ARCH/754-875---NDIKQLPI
A1HPY6_9FIRM/461-579---ETLERLPV
Q1CU50_HELPH/387-501---KDLECLPL
C5CH49_KOSOT/887-1032---IYVSKIPV
Q02YN3_LACLS/1013-1132---NELGEFPI
A6C2K5_9PLAN/396-510---ADLGALPI
B7A9M4_THEAQ/290-405---RMLERLPV
D5UBA4_BRAM5/209-336---IYTSLLPI
Y3402_METJA/955-1077---EELRELPI
Q12U44_METBU/826-966---QHVRNFPI
B9DU79_STRU0/1021-1140---NELGDFPI
D0LRP5_HALO1/739-867---KHIGEFPL
A4CM25_ROBBH/762-881---NELKELPV
B8JFL3_ANAD2/737-854---FSLNALPF
D6XZV1_BACIE/524-637---KHIESIPI
B5YJE4_THEYD/332-454---TQLKNLPL
Q24XG1_DESHY/339-452---SSLARLPI
B0JLC9_MICAN/1017-1136---RSISQLPI
C4G3N9_ABIDE/491-604---AHIEKIPI
B3QU01_CHLT3/277-390---LQLAMIPI
C4GI54_9NEIS/774-890---AHVEQLPM
A5N0R0_CLOK5/377-495---FSLDRIPI
A6GW88_FLAPJ/761-878---YQLKQLPI
Q3IQE9_NATPD/931-1083---KYLEPLPV
C9L6V5_RUMHA/544-657---SHIENIPI
D5UBA8_BRAM5/218-336---KHIFNLPI
Q647Q6_9ARCH/759-878---GHIAKLPI
Q72IB2_THET2/280-395---AMLERFPL
C0R107_BRAHW/240-364---TFLEKIPM
Q6E3B7_9BACT/299-413---AMLARVPV
Q9APD5_GEOSE/455-582---GYYHYLPT
C2LZV9_STAHO/856-975---RDIKNLPL
A8SWJ6_9FIRM/502-615---SHIESLPI
B0VG24_CLOAI/333-455---TQLKNLPV
Q6UQ63_GEOSE/393-512---YEIDCFPV

PF01420

T1S1_METJA/225-407KK.QKKEKLQR
Q38085_9VIRU/6-167HF.NLKSRIKE
T1SP_ECOLX/15-201TA.ELTAELSM
O25209_HELPY/1-179ENNHKINELLH
Q7P6F9_FUSNV/5-165SG.SINTQIYD
O25519_HELPY/109-276LA.GIPAEIKA
T1SX_MYCGE/198-359DQYKKELSSLT
O27024_METTH/222-387LT.ERKVKLEN
Q0I2C2_HAES1/191-347EQ.KQIKNILK
Q9ZJE8_HELPJ/211-381MK.QTIQGVVQ
Q47280_ECOLX/200-383TE.GLPREIEL
T1SX_MYCGE/10-171ENLASLIEINR
O27024_METTH/15-193EKVNKEIGVTE
T1S_SALTY/7-187TK.ARLEQIPQ
T1S_SALTY/225-410EK.QVNNALTR
T1S1_ECOLX/200-381TE.GLPREIEL
O30379_MYCPL/91-256NLLKQKKKLLE
O68172_9LACT/234-414HQ.RKLDLLKE
O52274_LACLL/215-398HQ.RKLDLLKE
T1S1_ECOLX/15-183TA...ELNMRK
T1SH_MYCPN/62-225VE.GIPAEIEM
Q0I2C1_HAES1/15-176EMKNLVAILKD
O54432_9LACT/215-394HQ.RKLDFLKE
T1SA_MYCPN/147-310NE.GIPAEIEL
Y1531_METJA/22-203IG.TINKQIEV
T1SD_ECOLX/7-162TK.ARLEQIPQ
T1SH_METJA/22-201ENKKKQNEILE
O52188_STRTR/21-198HQ.RKLDLLKE
T1SB_MYCPN/179-342SNWGIYKEIEL
Q88AU8_PSESM/13-174...RLLNEAKT
Q1WR64_LACS1/1-159EA.DRLQQLEA
Q17V99_HELAH/11-175EQ.CRLAELEA
T4BB_BACCO/4-164LS.NMEKNFDV
Q88AU8_PSESM/192-354...ALRARVEL
O25479_HELPY/241-404LA.GIPAEIKA
T1SI_HAEIN/195-369TE.GLPLAIEQ
Q4HPG5_CAMUP/917-1080QK.ECIKSVVL
O68173_9LACT/224-383HQ.RKLAFVER
O25479_HELPY/13-194NT.ELNTELKA
Q0I2C2_HAES1/12-173EN.KQRNDLKE
Q1WR64_LACS1/216-380EKLTIKDVVEY
T1SG_MYCPN/114-279TE.GIPAEIEL
T1SI_HAEIN/16-176TS.ELTSELTS
Q2HWD3_HELPX/11-179EQ.CRLAELEA
Q1CRB1_HELPH/11-176EQ.CRLAELEA
O34140_KLEPN/2-158GK.QINQTLEQ
T1S1_METJA/17-197IE.KSINKLER
T1SX_MYCPN/10-171EHLNELIEVNR
T1SB_ECOLX/22-192TK.ARLEQIPQ
T1SH_HAEIN/1-179NT.QINQTLEQ
O28563_ARCFU/140-319ER.KRKEKLER
O54432_9LACT/15-189HQ.RKLDLLKE
Y1218_METJA/22-191IN.KQIEVLNK
T1S_SALPO/237-404EK.QVNNALTR
T4BB_BACCO/178-337EN.KVVGRTTE
T1SD_ECOLX/213-385EK.QVNNALAR
Q47280_ECOLX/15-181TA.ELTAELNM
O52274_LACLL/14-189HQ.RKLDLLKE
Q50356_MYCPL/215-384LK.QKKKLLEK
O68169_9LACT/228-396HQ.RKLDLLKE
Q4HPG5_CAMUP/705-862EA.ERLQELEA
T1SH_HAEIN/266-440EK.TLSNSIEN
Y1218_METJA/220-404KR.KEKEQIEK
T1SP_ECOLX/220-383TEVSRVKSSCA
Q1JWR8_DESAC/162-320SYSAAIELVHS

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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