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104  structures 4781  species 6  interactions 19148  sequences 100  architectures

Clan: FKBP (CL0487)

Summary

FKBP-like superfamily Add an annotation

This superfamily includes the FKBP domain which catalyses the peptidyl-prolyl cis-trans isomerisation reaction. The superfamily also includes the C-terminal domain of GreA and the c-terminal dmoain of 3-mercaptopyruvate sulfurtransferase.

This clan contains 5 families and the total number of domains in the clan is 19148. The clan was built by A Bateman.

Members

This clan contains the following 5 member families:

DUF1930 GreA_GreB Rotamase Rotamase_2 Rotamase_3

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
GreA_GreB (PF01272) 7631 (39.9%) View
Rotamase (PF00639) 5141 (26.8%) View
Rotamase_3 (PF13616) 3691 (19.3%) View
Rotamase_2 (PF13145) 2673 (14.0%) View
DUF1930 (PF09122) 12 (0.1%) View
Total: 5 Total: 19148 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 6 interactions for this clan. More...

Interacting families
A B
GreA_GreB GreA_GreB
GreA_GreB_N
DUF1930 Rhodanese
Rotamase WW
Rotamase
SurA_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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