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392  structures 5229  species 3  interactions 42734  sequences 122  architectures

Clan: PRTase-like (CL0533)

Summary

PRPP synthetase-associated protein 1 Add an annotation

This superfamily of phosphoribosyl-transferases (PRTases) and phosphoribosyl-pyrophosphate synthetase-like protein families is characterised by a core fold of three layers, a/b/a with a mixed beta-sheet of six strands. In one of the families consists of two domains of this fold.

This clan contains 6 families and the total number of domains in the clan is 42734. The clan was built by P Coggill.

Members

This clan contains the following 6 member families:

Pribosyl_synth Pribosyltran PRTase_1 PRTase_2 PRTase_3 UPRTase

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Pribosyltran (PF00156) 30853 (72.2%) View
Pribosyl_synth (PF14572) 6166 (14.4%) View
UPRTase (PF14681) 5012 (11.7%) View
PRTase_1 (PF11202) 350 (0.8%) View
PRTase_2 (PF15609) 330 (0.8%) View
PRTase_3 (PF15610) 23 (0.1%) View
Total: 6 Total: 42734 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
Pribosyltran Pribosyltran
GATase_2
PuR_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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