Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
380  structures 5071  species 5  interactions 79539  sequences 348  architectures

Clan: HEXAPEP (CL0536)

Summary

Hexapeptide repeat superfamily Add an annotation

This superfamily is characterised by superhelical turns made up of three short strands duplicated many times; the sequence hexapeptide repeats correspond to individual strands. These hexapeptide repeat regions occur in a range of transferase enzymes.

This clan contains 2 families and the total number of domains in the clan is 79539. The clan was built by P Coggill.

Literature references

  1. Vaara M;, FEMS Microbiol Lett. 1992;76:249-254.: Eight bacterial proteins, including UDP-N-acetylglucosamine acyltransferase (LpxA) and three other transferases of Escherichia coli, consist of a six-residue periodicity theme. PUBMED:1427014 EPMC:1427014

Members

This clan contains the following 2 member families:

Hexapep Hexapep_2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Hexapep (PF00132) 70883 (89.1%) View
Hexapep_2 (PF14602) 8656 (10.9%) View
Total: 2 Total: 79539 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There are 5 interactions for this clan. More...

Interacting families
A B
Hexapep Hexapep
NTP_transferase
IspD
LpxD
SATase_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...