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1  structure 316  species 0  interactions 1604  sequences 23  architectures

Clan: GCP (CL0540)

Summary

Gamma-tubulin complex superfamily Add an annotation

This superfamily carries families of proteins all derived via gene-duplication events that act together in the gamma-tubulin complex. This complex is required for microtubule nucleation at the centrosome.

This clan contains 2 families and the total number of domains in the clan is 1604. The clan was built by P Coggill.

Literature references

  1. Murphy SM, Preble AM, Patel UK, O'Connell KL, Dias DP, Moritz M, Agard D, Stults JT, Stearns T;, Mol Biol Cell. 2001;12:3340-3352.: GCP5 and GCP6: two new members of the human gamma-tubulin complex. PUBMED:11694571 EPMC:11694571

Members

This clan contains the following 2 member families:

GCP5-Mod21 Spc97_Spc98

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Spc97_Spc98 (PF04130) 1599 (99.7%) View
GCP5-Mod21 (PF14609) 5 (0.3%) View
Total: 2 Total: 1604 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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