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0  structures 303  species 0  interactions 446  sequences 11  architectures

Clan: APCOP-app_sub (CL0545)

Summary

Clathrin (AP) and COPI appendage platform subdomain Add an annotation

This superfamily is characterised by subdomains from the clathrin and coatomer appendages. The superfamily possesses a single protein/protein interaction site that in yeast binds to the ARFGAP Glo3p, and in mammalian gamma-COP binds to a Glo3p orthologue, ARFGAP2 [1].

This clan contains 2 families and the total number of domains in the clan is 446. The clan was built by P Coggill.

Literature references

  1. Watson PJ, Frigerio G, Collins BM, Duden R, Owen DJ; , Traffic. 2004;5:79-88.: Gamma-COP appendage domain - structure and function. PUBMED:14690497 EPMC:14690497

Members

This clan contains the following 2 member families:

AP4E_app_platf Coatomer_b_Cpla

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Coatomer_b_Cpla (PF14806) 371 (83.2%) View
AP4E_app_platf (PF14807) 75 (16.8%) View
Total: 2 Total: 446 Clan alignment
 

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Family relationships

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Species distribution

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