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10  structures 5252  species 1  interaction 48799  sequences 163  architectures

Clan: CPA_AT (CL0064)

Summary

CPA/AT transporter superfamily Add an annotation

This Clan contains transporter proteins that belong to the CPA superfamily and AT superfamily according to TCDB [1].

This clan contains 13 families and the total number of domains in the clan is 48799. The clan was built by A Bateman.

Literature references

  1. Chang AB, Lin R, Keith Studley W, Tran CV, Saier MH Jr; , Mol Membr Biol 2004;21:171-181.: Phylogeny as a guide to structure and function of membrane transport proteins. PUBMED:15204625 EPMC:15204625

Members

This clan contains the following 13 member families:

Asp-Al_Ex Cons_hypoth698 DUF340 DUF4137 DUF819 DUF897 Glt_symporter KdgT Mem_trans Na_H_antiport_1 Na_H_Exchanger OAD_beta SBF

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Na_H_Exchanger (PF00999) 17250 (35.3%) View
Mem_trans (PF03547) 9093 (18.6%) View
SBF (PF01758) 4441 (9.1%) View
Asp-Al_Ex (PF06826) 4439 (9.1%) View
Cons_hypoth698 (PF03601) 3130 (6.4%) View
Na_H_antiport_1 (PF06965) 2392 (4.9%) View
Glt_symporter (PF03616) 1846 (3.8%) View
DUF4137 (PF13593) 1645 (3.4%) View
OAD_beta (PF03977) 1424 (2.9%) View
DUF340 (PF03956) 1369 (2.8%) View
KdgT (PF03812) 900 (1.8%) View
DUF819 (PF05684) 548 (1.1%) View
DUF897 (PF05982) 322 (0.7%) View
Total: 13 Total: 48799 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There is 1 interaction for this clan. More...

Interacting families
A B
Na_H_antiport_1 Na_H_antiport_1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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