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193  structures 4892  species 7  interactions 38354  sequences 1986  architectures

Clan: CoA-acyltrans (CL0149)

Summary

CoA-dependent acyltransferase superfamily Add an annotation

All characterised families in this clan are involved in CoA-dependent acyltransferase. All families have a characteristic HXXXD motif.

This clan contains 7 families and the total number of domains in the clan is 38354. The clan was built by RD Finn.

Members

This clan contains the following 7 member families:

2-oxoacid_dh AATase Carn_acyltransf CAT Condensation Transferase WES_acyltransf

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Condensation (PF00668) 20609 (53.7%) View
2-oxoacid_dh (PF00198) 10039 (26.2%) View
Transferase (PF02458) 3130 (8.2%) View
Carn_acyltransf (PF00755) 1813 (4.7%) View
WES_acyltransf (PF03007) 1646 (4.3%) View
CAT (PF00302) 768 (2.0%) View
AATase (PF07247) 349 (0.9%) View
Total: 7 Total: 38354 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 7 interactions for this clan. More...

Interacting families
A B
CAT CAT
NO_synthase
Carn_acyltransf Carn_acyltransf
Condensation PP-binding
Condensation
Transferase Transferase
2-oxoacid_dh 2-oxoacid_dh

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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