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77  structures 5888  species 3  interactions 33570  sequences 100  architectures

Clan: EF-G_C (CL0437)

Summary

Transcription elongation factor G C-terminal Add an annotation

This superfamily is characterised by being an alpha-beta 2-Layer Sandwich. It is found in EF2 proteins from both prokaryotes and eukaryotes, as well as in some tetracycline resistance proteins, peptide chain release factors ], and in the C-terminal region of the bacterial hypothetical protein, YigZ.

This clan contains 4 families and the total number of domains in the clan is 33570. The clan was built by P Coggill.

Members

This clan contains the following 4 member families:

DUF1949 EFG_C EFG_II SBDS_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
EFG_C (PF00679) 18629 (55.5%) View
EFG_II (PF14492) 11565 (34.5%) View
DUF1949 (PF09186) 2861 (8.5%) View
SBDS_C (PF09377) 515 (1.5%) View
Total: 4 Total: 33570 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
EFG_C GTP_EFTU
EFG_IV
SBDS_C SBDS

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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