Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
154  structures 3092  species 11  interactions 7355  sequences 20  architectures

Clan: FumRed-TM (CL0335)

Summary

Fumarate reductase respiratory complex transmembrane subunits Add an annotation

This superfamily constitutes two distinct families: in one family the common fold is contained in a single-chain subunit, in the other it is formed by two chains.

This clan contains 5 families and the total number of domains in the clan is 7355. The clan was built by P Coggill.

Members

This clan contains the following 5 member families:

CybS DUF1691 Fumarate_red_C Fumarate_red_D Sdh_cyt

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Sdh_cyt (PF01127) 5134 (69.8%) View
Fumarate_red_D (PF02313) 816 (11.1%) View
Fumarate_red_C (PF02300) 798 (10.8%) View
CybS (PF05328) 384 (5.2%) View
DUF1691 (PF07950) 223 (3.0%) View
Total: 5 Total: 7355 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There are 11 interactions for this clan. More...

Interacting families
A B
Fumarate_red_D Fer4
Fumarate_red_C
Fumarate_red_D
Sdh_cyt Fer2
FAD_binding_2
Sdh_cyt
Succ_DH_flav_C
Fumarate_red_C Fer4
FAD_binding_2
Fumarate_red_D
Succ_DH_flav_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...