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5  structures 359  species 0  interactions 2519  sequences 40  architectures

Clan: GOLD-like (CL0521)

Summary

Sec14-like superfamily of golgi trafficking Add an annotation

This superfamily is characterised by proteins with a sandwich structure of 8 strands in 2 sheets as a jelly-roll. The structure has similarity to the Nucleoplasmin-like/VP fold. The members are all involved in golgi trafficking.

This clan contains 2 families and the total number of domains in the clan is 2519. The clan was built by P Coggill.

Literature references

  1. Anantharaman V, Aravind L; , Genome Biol 2002;3:research0023.: The GOLD domain, a novel protein module involved in Golgi function and secretion. PUBMED:12049664 EPMC:12049664
  2. Mousley CJ, Tyeryar KR, Vincent-Pope P, Bankaitis VA;, Biochim Biophys Acta. 2007;1771:727-736.: The Sec14-superfamily and the regulatory interface between phospholipid metabolism and membrane trafficking. PUBMED:17512778 EPMC:17512778

Members

This clan contains the following 2 member families:

EMP24_GP25L GOLD_2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
EMP24_GP25L (PF01105) 2288 (90.8%) View
GOLD_2 (PF13897) 231 (9.2%) View
Total: 2 Total: 2519 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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