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446  structures 5155  species 3  interactions 45938  sequences 682  architectures

Clan: HD_PDEase (CL0237)

Summary

HD/PDEase superfamily Add an annotation

This clan includes a range of phosphohydrolase enzymes with a common helical fold.

This clan contains 10 families and the total number of domains in the clan is 45938. The clan was built by A Bateman.

Members

This clan contains the following 10 member families:

DUF706 HD HD_2 HD_3 HD_4 HD_5 HDOD PDEase_I TraI_2 tRNA_NucTran2_2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
HD (PF01966) 24448 (53.2%) View
HD_4 (PF13328) 7076 (15.4%) View
HDOD (PF08668) 3180 (6.9%) View
HD_5 (PF13487) 3171 (6.9%) View
PDEase_I (PF00233) 2707 (5.9%) View
HD_3 (PF13023) 2536 (5.5%) View
tRNA_NucTran2_2 (PF13735) 1530 (3.3%) View
TraI_2 (PF07514) 472 (1.0%) View
HD_2 (PF12917) 447 (1.0%) View
DUF706 (PF05153) 371 (0.8%) View
Total: 10 Total: 45938 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
PDEase_I PDEase_I
HD HD
RelA_SpoT

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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