Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
147  structures 4353  species 3  interactions 8980  sequences 130  architectures

Clan: MACRO (CL0223)

Summary

MACRO domain superfamily Add an annotation

This superfamily includes the Macro domain as well as the amino terminal domain from peptidase M17 proteins.

This clan contains 3 families and the total number of domains in the clan is 8980. The clan was built by A Bateman.

Literature references

  1. Karras GI, Kustatscher G, Buhecha HR, Allen MD, Pugieux C, Sait F, Bycroft M, Ladurner AG; , EMBO J 2005;24:1911-1920.: The macro domain is an ADP-ribose binding module. PUBMED:15902274 EPMC:15902274

Members

This clan contains the following 3 member families:

Macro Macro_2 Peptidase_M17_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Macro (PF01661) 5297 (59.0%) View
Peptidase_M17_N (PF02789) 3629 (40.4%) View
Macro_2 (PF14519) 54 (0.6%) View
Total: 3 Total: 8980 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
Macro Macro
Peptidase_M17_N Peptidase_M17
Peptidase_M17_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...