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338  structures 5508  species 9  interactions 42917  sequences 577  architectures

Clan: NTP_transf (CL0260)

Summary

Nucleotidyltransferase superfamily Add an annotation

This clan contains a diverse set of nucleotidyltransferase enzymes.

This clan contains 22 families and the total number of domains in the clan is 42917. The clan was built by A Bateman.

Members

This clan contains the following 22 member families:

Adenyl_cycl_N Adenyl_transf Aminoglyc_resit DNA_pol_B_palm DUF1693 DUF1814 DUF2204 DUF294 DUF925 DZF GlnE GrpB LicD Mab-21 MdcG Mmp37 NTP_transf_2 NTP_transf_5 Nuc-transf PolyA_pol Pox_polyA_pol RelA_SpoT

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
NTP_transf_2 (PF01909) 8895 (20.7%) View
RelA_SpoT (PF04607) 8755 (20.4%) View
PolyA_pol (PF01743) 6516 (15.2%) View
GlnE (PF03710) 4102 (9.6%) View
LicD (PF04991) 2479 (5.8%) View
DUF1814 (PF08843) 2210 (5.1%) View
GrpB (PF04229) 1502 (3.5%) View
DUF294 (PF03445) 1219 (2.8%) View
Adenyl_cycl_N (PF12633) 1003 (2.3%) View
Nuc-transf (PF10127) 840 (2.0%) View
DUF925 (PF06042) 786 (1.8%) View
Mab-21 (PF03281) 746 (1.7%) View
continued
Pfam family Num. domains Alignment
NTP_transf_5 (PF14907) 654 (1.5%) View
DNA_pol_B_palm (PF14792) 629 (1.5%) View
Adenyl_transf (PF04439) 625 (1.5%) View
DZF (PF07528) 544 (1.3%) View
Mmp37 (PF09139) 355 (0.8%) View
MdcG (PF10620) 349 (0.8%) View
DUF1693 (PF07984) 296 (0.7%) View
Aminoglyc_resit (PF10706) 186 (0.4%) View
DUF2204 (PF09970) 161 (0.4%) View
Pox_polyA_pol (PF03296) 65 (0.2%) View
Total: 22 Total: 42917 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 9 interactions for this clan. More...

Interacting families
A B
PolyA_pol PolyA_pol
NTP_transf_2 NTP_transf_2
PAP_RNA-bind
PAP_central
KNTase_C
tRNA_NucTransf2
DNA_pol_lambd_f
RelA_SpoT HD
GrpB GrpB

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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