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156  structures 5379  species 9  interactions 23959  sequences 130  architectures

Clan: PFL-like (CL0339)

Summary

PFL-like glycyl radical enzyme superfamily Add an annotation

The N- and C-terminal halves of the structure have similar topologies but in some cases only one is represented by the members here, viz; the C-terminal domain of the R1 subunit of ribonucleotide reductase, and the N-terminal of PFL. The full-length structure is modelled by NRDD.

This clan contains 6 families and the total number of domains in the clan is 23959. The clan was built by P Coggill.

Members

This clan contains the following 6 member families:

DUF3029 DUF711 Gly_radical NRDD PFL Ribonuc_red_lgC

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Ribonuc_red_lgC (PF02867) 8373 (34.9%) View
Gly_radical (PF01228) 5415 (22.6%) View
PFL (PF02901) 4920 (20.5%) View
NRDD (PF13597) 3413 (14.2%) View
DUF711 (PF05167) 1207 (5.0%) View
DUF3029 (PF11230) 631 (2.6%) View
Total: 6 Total: 23959 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 9 interactions for this clan. More...

Interacting families
A B
Gly_radical PFL
DUF711 DUF711
Ribonuc_red_lgC Ribonuc_red_sm
Ribonuc_red_lgN
Ribonuc_red_lgC
ATP-cone
RNR_N
PFL Gly_radical
PFL

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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