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814  structures 6922  species 26  interactions 76571  sequences 1796  architectures

Clan: Peptidase_CA (CL0125)

Summary

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
NLPC_P60 (PF00877) 11783 (15.4%) View
UCH (PF00443) 8903 (11.6%) View
Peptidase_C1 (PF00112) 7017 (9.2%) View
Transglut_core (PF01841) 6914 (9.0%) View
CHAP (PF05257) 5579 (7.3%) View
Peptidase_C39 (PF03412) 3484 (4.6%) View
Peptidase_C48 (PF02902) 3178 (4.2%) View
Peptidase_C2 (PF00648) 2514 (3.3%) View
DUF830 (PF05708) 2265 (3.0%) View
OTU (PF02338) 2248 (2.9%) View
Peptidase_C39_2 (PF13529) 2151 (2.8%) View
Acetyltransf_2 (PF00797) 2001 (2.6%) View
Peptidase_C1_2 (PF03051) 1894 (2.5%) View
Transglut_core2 (PF13369) 1446 (1.9%) View
Peptidase_C12 (PF01088) 1199 (1.6%) View
Peptidase_C6 (PF00851) 1177 (1.5%) View
LRAT (PF04970) 808 (1.1%) View
Peptidase_C93 (PF06035) 779 (1.0%) View
Viral_protease (PF08715) 760 (1.0%) View
Peptidase_C54 (PF03416) 700 (0.9%) View
Rad4 (PF03835) 550 (0.7%) View
Peptidase_C33 (PF05412) 524 (0.7%) View
DUF1287 (PF06940) 504 (0.7%) View
Amidase_6 (PF12671) 491 (0.6%) View
Peptidase_C78 (PF07910) 453 (0.6%) View
Peptidase_C28 (PF05408) 452 (0.6%) View
Peptidase_C65 (PF10275) 450 (0.6%) View
DUF1460 (PF07313) 430 (0.6%) View
Peptidase_C47 (PF05543) 395 (0.5%) View
UCH_1 (PF13423) 393 (0.5%) View
Transpep_BrtH (PF14399) 388 (0.5%) View
continued
Pfam family Num. domains Alignment
EDR1 (PF14381) 364 (0.5%) View
DUF1175 (PF06672) 358 (0.5%) View
Peptidase_C10 (PF01640) 317 (0.4%) View
YopJ (PF03421) 290 (0.4%) View
Transglut_core3 (PF13471) 283 (0.4%) View
Phytochelatin (PF05023) 280 (0.4%) View
Transglut_i_TM (PF14400) 271 (0.4%) View
Peptidase_C9 (PF01707) 257 (0.3%) View
Amidase_5 (PF05382) 235 (0.3%) View
Peptidase_C31 (PF05410) 229 (0.3%) View
Peptidase_C32 (PF05411) 221 (0.3%) View
DUF3335 (PF11814) 210 (0.3%) View
Peptidase_C42 (PF05533) 200 (0.3%) View
Peptidase_C58 (PF03543) 182 (0.2%) View
Guanylate_cyc_2 (PF09778) 169 (0.2%) View
DUF2272 (PF10030) 136 (0.2%) View
Peptidase_C5 (PF00770) 133 (0.2%) View
Peptidase_C23 (PF05379) 125 (0.2%) View
Peptidase_C16 (PF01831) 113 (0.1%) View
Peptidase_C27 (PF05407) 69 (0.1%) View
DUF553 (PF04473) 69 (0.1%) View
Peptidase_C98 (PF15499) 62 (0.1%) View
Peptidase_C7 (PF01830) 61 (0.1%) View
Peptidase_C21 (PF05381) 44 (0.1%) View
Peptidase_C70 (PF12385) 20 (0.0%) View
Peptidase_C8 (PF03569) 18 (0.0%) View
Peptidase_C34 (PF05413) 13 (0.0%) View
Peptidase_C36 (PF05415) 8 (0.0%) View
Peptidase_C71 (PF12386) 4 (0.0%) View
Total: 60 Total: 76571 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

We could not retrieve a family relationship diagram for this clan.

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 26 interactions for this clan. More...

Interacting families
A B
Peptidase_C12 ubiquitin
Peptidase_C12
DUF1460 DUF1460
Peptidase_C2 Peptidase_C2
Calpain_III
Peptidase_C1 Cystatin
Peptidase_C1
Inhibitor_I29
CathepsinC_exc
Inhibitor_I42
CHAP GSP_synth
UCH ubiquitin
UCH
Rad4 BHD_1
Peptidase_C47 Peptidase_C47
Transglut_core Transglut_N
Transglut_C
Transglut_core
Peptidase_C48 ubiquitin
Peptidase_C48
Phytochelatin Phytochelatin
OTU OTU
Peptidase_C54 Atg8
Peptidase_C54
Acetyltransf_2 Acetyltransf_2
Peptidase_C1_2 Peptidase_C1_2

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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