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1  structure 2542  species 0  interactions 7438  sequences 60  architectures

Clan: Steroid_dh (CL0115)

Summary

Steroid oxidoreductase superfamily Add an annotation

This clan includes several enzymes, including steroid dehydrogenases and isoprenylcysteine carboxyl methyltransferase enzymes. These protein contain a varying number of transmembrane regions.

This clan contains 6 families and the total number of domains in the clan is 7438. The clan was built by A Bateman.

Members

This clan contains the following 6 member families:

DUF1295 ERG4_ERG24 ICMT NnrU PEMT Steroid_dh

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PEMT (PF04191) 2350 (31.6%) View
ICMT (PF04140) 1448 (19.5%) View
Steroid_dh (PF02544) 1178 (15.8%) View
ERG4_ERG24 (PF01222) 987 (13.3%) View
DUF1295 (PF06966) 924 (12.4%) View
NnrU (PF07298) 551 (7.4%) View
Total: 6 Total: 7438 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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