# STOCKHOLM 1.0
#=GF ID   DDE_5
#=GF AC   PF13546.1
#=GF DE   DDE superfamily endonuclease
#=GF AU   Bateman A
#=GF SE   Jackhmmer:C0W963
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CC   This family of proteins are related to Pfam:PF00665 and are
#=GF CC   probably endonucleases of the DDE superfamily. Transposase
#=GF CC   proteins are necessary for efficient DNA transposition. This
#=GF CC   domain is a member of the DDE superfamily, which contain three
#=GF CC   carboxylate residues that are believed to be responsible for
#=GF CC   coordinating metal ions needed for catalysis. The catalytic
#=GF CC   activity of this enzyme involves DNA cleavage at a specific site
#=GF CC   followed by a strand transfer reaction.
#=GF SQ   14
#=GS C6HU64_9BACT/37-317  AC C6HU64.1
#=GS C0CZW6_9CLOT/28-306  AC C0CZW6.1
#=GS Q2NYG4_XANOM/5-292   AC Q2NYG4.1
#=GS Q7TTG5_RHOBA/19-299  AC Q7TTG5.1
#=GS A3ZP63_9PLAN/12-290  AC A3ZP63.1
#=GS D3V8L4_XENBS/11-263  AC D3V8L4.1
#=GS C8XKW3_NAKMY/17-271  AC C8XKW3.1
#=GS B0CD02_ACAM1/13-245  AC B0CD02.1
#=GS B3JL97_9BACE/6-266   AC B3JL97.1
#=GS C9KTM6_9BACE/5-268   AC C9KTM6.1
#=GS Q2JB45_FRASC/8-271   AC Q2JB45.1
#=GS Q4C967_CROWT/9-287   AC Q4C967.1
#=GS B9LG31_CHLSY/19-296  AC B9LG31.1
#=GS C0W963_9FIRM/10-284  AC C0W963.1
C6HU64_9BACT/37-317             SLVQLHNGYQNI....LGDA..RLSRLGQAYLAGLCSNIERKSVEPIALALLEAPGRVR....SLQQFISSYDWDEAAMFARYRSQVAETLVAGADPARSMLTLDSSEQVKS.....GKESAGVARQYCGRLG..KVENCQSGVFVGYVSGKG.QRLLDAQLYLP.KKWIEDDDY...AERREKTGIPKDQVFKTKPQIAGEMIRDLDRSGLFPAAW..IGCDATFG.MDRKFLAELPEGR..SYLASVRSNLHVLTSAPQWKVPKRHASRGKAPSKLRLTE....TPMTVSGLA......KTFSFTPMILKDGAKGP
C0CZW6_9CLOT/28-306             CLEPYLHQYDCA....FTSQ..KQSKHFANFVRGLLSPLDRKSIEPIALH.LAGEKSVR....PMQQFFTRAPLKEDDILDTYQQLLAAQL....NHTGSMLSVDDTSFVKK.....GTHSIGVKRQYCGRPG..KRENCQVGVFLSYAGDSG.YGLVDYELYIP.QEWFQDSH....QDLRTRCQLPEQRRFLTKNQIAQNLLNHAFETGRFQAQW..IGCDAAYG.CDHAFLDGLKLPGEVWYFAATNAKEQVFLEQPQICNPEPGKN.RGRPKKHPIWTI...QPVSVKSIA....EDPAAPWEQVTLAEGSKGP
Q2NYG4_XANOM/5-292              TLEVRFEQYREVVAAALSHA..DRKQPAHWYLKGLLLPGGRKSVELMAA..RVHPQNVRSAHQSMHHLVADADWSDQALLAAVAAQVLPPL..SRKSAACHWIVDDTGFSKK.....GVHSVGVARQYCDRLG..KTDNCQVAVSLSIANEHG.SLPVGYRLYLP.EQWTQD......TVRRKKAGVPDQVVFQTKTALAMDQIDSALSTG.IAAGV..VLADAAYG.TETHWRDQLSERG.LLYMVGVRSNTKVWWGSHQPAPMPPASPKGGRPRTRPMRDSAH.APISVHEVA...QSLPARTYRQVSWRQGSDAT
Q7TTG5_RHOBA/19-299             RLNAYLARFGDC....FRRS..DTRAHLTTYVRGQLSDLDAKSVEPIA...LQAGTPVR....TLQEFIAQHRWDEDGLRRRLIHIVRDEH....VNKNTVAIIDETSDVKK.....GDKTPGVQRQWCGKVG..KQENCIVTVHLAAANEDF.HCMVDGELFLP.ESWSND......RERCAAAGIPDEMVYRPKWQIALELLDRSKEEG.IEYPW..LTADEGYG.GKPGFLEALADRD.QKFVLEVPRTFSVWEKHPEVTEQPYRKGGRGRGRKTPRVKSGESSPRSVETVFWHGEAMKAKRWKRYRVKDGEKGP
A3ZP63_9PLAN/12-290             ELTRYLNRFADC....FSRK..DTRAHLPVYVEGQLSDLPRKSAEPIA...LAAGVPVR....TLQEFLSQLRWDEDALRTRLQTMVAAEH....ASSHSIGIIDETSDVKK.....GIKTPGVQRQWCGCAG..KTENCIVTVHLAYAANDF.HCLLDGELFLP.ESWAED......RARCQEAGIPDEMTYRSKWEIALEQYDRAIANG.IAFEW..LTFDEGYG.SKGPFLRALSERR.QKYVAEVPVTMTGWLTPPKVTSRRSQR..TGRPARIPRLTKNSPRPQRIDELLNDHPKLRDQAWKKYRIKDGEKGP
D3V8L4_XENBS/11-263             ELLSLHTRLAPL....FHHH..APQQRSLAYLRGLLSDVERKNGWQLAE..WIGERTPD....GVQHLLERAHWDVDIARDILRDYVTEHL....GDEHGVLIVDETGFIKK.....GTHSAGVQRQYSGTAG..RVENSQTGVFLCYAGQGG.HAFIDRALYLP.RQWTDD......RPRCEAAGIPDAVPFATKPQLARQMLERAFEAG.VLCRW..VTADAIYG.QDRRLRCWLESRY.QPFVLAIPKNEPLWWQGP..........................TFVRADKIV...DNLTPQRWETHSAGWGAKGE
C8XKW3_NAKMY/17-271             GLEDLLARMTPI....FYRT..ESRRHAEQYLRGLLSPLQRKNGWTIAE..HVGESEPK....ALQRFLNISPWDVEQLLVLNRDYVMGHL....ASPEAILVADPTGFAKK.....GKKSVGVQRQYSGTLG..RIDNCQIATFLAYVTPGRDRVLIDRRLYLPEKSWLAD......PARCAEAGVTADTVFRTRPEQVIEMIKVARAAD.VPFAW..FTADEEFG.QNPGLREYLENTG.ISYVMAIPKNTTFTDHTG...........RSRP...............VSEIP...LSLKPTAWQRRACGIGAKGY
B0CD02_ACAM1/13-245             FVDEYCQLFAEL....FSQV..RSNEAFKHLHLGMINDIKRKSLPAIAR..AVGLENHQ....SLHHFLSESPWVASHLSDKSLDIILKIL....DGRRLILLIDETGDCKK.....GKSTDYVKRQYIGNVG..KKENGIVAVTAYGLFQGM.ILPLSFEVYKP.............RER.....LKEGDEYLSKPQIAAGMIRQLQGMG.FCFEL..VLADSLYGAAQTNFVNVLEELK.LPYILAIRSNHAVWLPAE......................................QAVFAEPWQSFE.RTFSNGT
B3JL97_9BACE/6-266              LLMQYQSECRNALES.VVNISKSFQKVFMDAMKLFMAIPNRVNFLQMGRYGCFSEQ.......TYRNNFENDDFDWFSFNEAIIREHL.......KGGRKAIAVDPSFIPKS.....GSKTPWIGYFWSGCAGEYKRGLEITGIGVIDVDN.H.ECMTLGSVQTPDNATLE.......SYGKNLVDWYSSYLISIQEHLKRISGT..............VVCDAFFS..KATFIKPLCENG.FHVISRFRNDAVLFYPTLENRTGK.....RGRPKLYDGKIDFENLDITRC......TEYKVNKGKLYGLKAYSKAL
C9KTM6_9BACE/5-268              ALDQYEEIVTDALKSCSAKLCKSFETAFIQLMILYMVLPRKINFTQMGRYSDSSEQ.......RFQQLFER.EFDWMQFNLFLMRQRFG......ESVRKAIAIDASYISKS.....GKKIPYIGKFWSGCASAMKRGLEILGIGIIDIDS.R.NCMMLCAEQTPDKAYMEKQ.....GEDYNLVDWYLDVLRKYKDKLLGITHH..............VVADARFS..KAKFVNEACLLG.FHVISRLRDDAALWYSHDGVRTGK.....RGRPRIKGEKIDFEKLDLQCCEI......LDIEGGRAYSVKAYSKGF
Q2JB45_FRASC/8-271              AVQQFTPQF.......YGCLTRRADALFELTDAVLCADGPVRDLVGLSP.....AAEHRRGHGALYGAINHGRVEISRLRRALAGLPLPRA....ADGRIVLGVDVSPWLRP......DAATSPGRLFCHTYGRGKGNAQMIPGW.........PYSFVAALEPGRTSWTAPLDAVRLGPDDDLTTVTAAQVRDVVGRLAAVGHHTAGDPNIL......VVFDAGYDVTRLAFLLAGLP...VDLVGRLRSDRVFRLPVLPRPPKA.....SGRPPRHGPE.....LPLADPASL....PTPTVTTTTETRRYGTAVA
Q4C967_CROWT/9-287              SVEEFLVWRSNL....FQEL.KARKETIIELLEALSSNQQAHSVVKLSLNPLF.RRDYNSLYRGIQEFLPTQTDPNYEQRIETLFSAVSRTIPPTSKHYNLFGIDTTPCPRR......FAETLADKTFIHYPNPIKGNKPINIGHCYSV.....ICALPDQIDTEKVPWAVPLSGERVPSKHKGVNQGNQQ............LKKIWQSSLFSDKLSVLVADSDYS..QKDFIGEQVKHEDVVTITRVRSDRVFYRQFIRDQNQAKT...SGHPRWYGDK.....FDLKDDQTWTEPDEVHHVPFTTKKGRQLTVTI
B9LG31_CHLSY/19-296             TLMQIITAHRPA....FRQE..RTFRRAVALLVGELFAFARHTVTQVLLALGMHDTDGT....AFYRLFSRSRFDEATLTACLCRETLKRC...SKHDPYVIGIDSTQIPRSSLTLPGTSWLHALRTAVVTRGIHRAQRFVHCAWLPPRVKGF.TRAIPLR.FLP...........AFPPKAAPADVPSANEWEGGLACIRWVRQQLTAAG.RAAQWVVVLADGACA.TVGMWRGV..PAQ.VALIVRTARNRCRSLLPPPPTG.......RGRPRRYGKRAPQPASWLTKQELFR..RKRVLVRGRRIAMRYQVHGP
C0W963_9FIRM/10-284             TVNRLLTTFSSL....FPSATRRTRHLLAWLLIAQLALESAPSVRCLFRQFLSKQTDAS..LNSYYRALGNGLVTDASIRQALALQALAIVPEALRQEPILLSVDDTSIAKW.....GKHFDGVGILYDHAKHDGKSYFN............G.HAFVSLTMSVP..VLHETAGKQQIRYIAVPIGYVMSNGEASKLTLACQLLDEVMPI..LEKRQVILLFDSWYA.KRELLAHALSYPN.LNVTCNARHDTAMFELPDSTAGR......RGRPPKYG.......KRLMLDEIANDLTNYLCRMDNYFVAHRLVKTR
#=GC seq_cons                   sLpphhspassh....Fspt..cpppthhthltGhlushpR+ol.tluh..hhutpssp....uhpchlspsca-tsplpttltp.shsph....sssptllslDsTshsKp.....Gp+osuVtRpasGshG..Ktpss.sslalh.sspth.pshlstplalP.ptWhps......t.+pphsslsss.hapsK.plAtthlcphhtsu.h.hth..lssDutYu.tcttFlptLpptt.hthlsplpsspshahtsst.ts.......pGRPthhs.h.....hslpssplh....phhspsapphsh+ttsKG.
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