Summary: Transcription factor BRX N-terminal domain
Transcription factor BRX N-terminal domain Provide feedback
The BREVIS RADIX (BRX) domain was characterised as being a transcription factor in plants regulating the extent of cell proliferation and elongation in the growth zone of the root [1,2]. BRX is rate limiting for auxin-responsive gene-expression by mediating cross-talk with the brassino-steroid pathway. BRX has a ubiquitous, although quantitatively variable role in modulating the growth rate in both the root and the shoot . This family features a short region, also alpha-helical, N-terminal to the repeated alpha-helices of family BRX, PF08381 . BRX is expressed in the vasculature and is rate-limiting for transcriptional auxin action .
Mouchel CF, Briggs GC, Hardtke CS;, Genes Dev. 2004;18:700-714.: Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel regulator of cell proliferation and elongation in the root. PUBMED:15031265 EPMC:15031265
Briggs GC, Mouchel CF, Hardtke CS;, Plant Physiol. 2006;140:1306-1316.: Characterization of the plant-specific BREVIS RADIX gene family reveals limited genetic redundancy despite high sequence conservation. PUBMED:16514016 EPMC:16514016
Scacchi E, Salinas P, Gujas B, Santuari L, Krogan N, Ragni L, Berleth T, Hardtke CS;, Proc Natl Acad Sci U S A. 2010;107:22734-22739.: Spatio-temporal sequence of cross-regulatory events in root meristem growth. PUBMED:21149702 EPMC:21149702
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Curation and family details
|Number in seed:||53|
|Number in full:||188|
|Average length of the domain:||38.00 aa|
|Average identity of full alignment:||41 %|
|Average coverage of the sequence by the domain:||4.56 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||1|
|Download:||download the raw HMM for this family|
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