# STOCKHOLM 1.0
#=GF ID   Replic_Relax
#=GF AC   PF13814.1
#=GF DE   Replication-relaxation
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:D0L6G0
#=GF GA   25.00 25.00;
#=GF TC   25.00 25.00;
#=GF NC   24.90 24.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11591133
#=GF RT   Complete nucleotide sequence and characterization of pUA140, a
#=GF RT   cryptic plasmid from Streptococcus mutans.
#=GF RA   Zou X, Caufield PW, Li Y, Qi F;
#=GF RL   Plasmid. 2001;46:77-85.
#=GF RN   [2]
#=GF RM   11251827
#=GF RT   Two atypical mobilization proteins are involved in plasmid
#=GF RT   CloDF13 relaxation.
#=GF RA   Nunez B, De La Cruz F;
#=GF RL   Mol Microbiol. 2001;39:1088-1099.
#=GF DR   INTERPRO; IPR025855;
#=GF CC   This family includes proteins which are essential for plasmid
#=GF CC   replication [1] and plasmid DNA relaxation [2].
#=GF SQ   47
#=GS B5J832_9RHOB/40-238  AC B5J832.1
#=GS Q5LU27_SILPO/33-231  AC Q5LU27.1
#=GS A5KRX3_9BACT/16-207  AC A5KRX3.1
#=GS A5KSE9_9BACT/20-208  AC A5KSE9.1
#=GS C3DCG9_BACTU/11-181  AC C3DCG9.1
#=GS C3BDL4_BACMY/14-230  AC C3BDL4.1
#=GS C3DAX8_BACTU/18-228  AC C3DAX8.1
#=GS C3IX13_BACTU/11-221  AC C3IX13.1
#=GS C2RX52_BACCE/14-224  AC C2RX52.1
#=GS A1BZ85_BACCE/27-218  AC A1BZ85.1
#=GS C3ICU8_BACTU/30-220  AC C3ICU8.1
#=GS B3ZY63_BACCE/27-217  AC B3ZY63.1
#=GS E3ICI0_GEOS0/17-227  AC E3ICI0.1
#=GS C6J6Z3_9BACL/10-201  AC C6J6Z3.1
#=GS C7Q8H2_CATAD/62-260  AC C7Q8H2.1
#=GS C9Z8H5_STRSW/21-220  AC C9Z8H5.1
#=GS C0E5J5_9CORY/37-239  AC C0E5J5.1
#=GS D0L6G0_GORB4/81-278  AC D0L6G0.1
#=GS C8X7Q8_NAKMY/2-208   AC C8X7Q8.1
#=GS Q2JEK1_FRASC/26-223  AC Q2JEK1.1
#=GS B6V2L8_BPSP1/34-230  AC B6V2L8.1
#=GS D3FAT2_CONWI/32-222  AC D3FAT2.1
#=GS A4X6D9_SALTO/23-216  AC A4X6D9.1
#=GS A4X414_SALTO/20-220  AC A4X414.1
#=GS D9T7V3_MICAI/26-228  AC D9T7V3.1
#=GS E8S2G0_MICSL/24-209  AC E8S2G0.1
#=GS D9T2Q6_MICAI/29-219  AC D9T2Q6.1
#=GS D9T0Y5_MICAI/1-197   AC D9T0Y5.1
#=GS D3Q517_STANL/29-218  AC D3Q517.1
#=GS C7PYS8_CATAD/28-212  AC C7PYS8.1
#=GS C7Q1Z1_CATAD/20-201  AC C7Q1Z1.1
#=GS A8L962_FRASN/45-232  AC A8L962.1
#=GS Q2JC28_FRASC/45-231  AC Q2JC28.1
#=GS Q2J9G6_FRASC/45-231  AC Q2J9G6.1
#=GS A8L5H0_FRASN/42-230  AC A8L5H0.1
#=GS A8L858_FRASN/43-231  AC A8L858.1
#=GS C7QG98_CATAD/49-242  AC C7QG98.1
#=GS A8L0V2_FRASN/23-211  AC A8L0V2.1
#=GS A8LB37_FRASN/37-222  AC A8LB37.1
#=GS D3FEB7_CONWI/60-249  AC D3FEB7.1
#=GS Q82RH5_STRAW/26-234  AC Q82RH5.1
#=GS E6TVE2_BACCJ/10-186  AC E6TVE2.1
#=GS E8STP8_GEOS2/13-168  AC E8STP8.1
#=GS B0FY00_BACTU/16-172  AC B0FY00.1
#=GS Q81EP7_BACCR/16-174  AC Q81EP7.1
#=GS Q6HJ44_BACHK/16-174  AC Q6HJ44.1
#=GS Q3HKZ6_9CAUD/16-173  AC Q3HKZ6.1
B5J832_9RHOB/40-238             LKHI..ERHGPLSSAYLHALSEDTHRC..KD....TSLRQLQKL.RAGGFL.MLPRQ.....QR.FTE.....HA.DFNPYIYDLTKQA......HTHL............IDLAI..............................AEPT...MRPT......G.HWG.HGADVASVTSAVD.IAA.ATE...G..VR..FIPAH.....EILAIKQA..SL.A......IPIGN..H..K.LIPDQLFALDYGG.......SYRAVMLEVDRGTEPKTSSAVRKSYASSIGLYRQ.MIEQNV......HQK.HYGL........KA.TTL....L
Q5LU27_SILPO/33-231             LKHI..ERHGPQGSHYLYELTRDTHRC..KD....TTLRQMQKL.RAGGYL.SLPHQ.....QR.ATE.....RA.EFNPYIYDLTQKA......EDHL............FDLGI.........D......EP...............T...VRPT......G.HWW.HSYMTSCVTSAID.IAA.LRA...G..VR..FIPAH.....EILA.IKD..VDLA......IPIGR..A..H.LIPDQLFALDYGG.......RYRAFALEVDRGTEPKTSPAKRKSWKRSIEQYRQ.IIEKQR......YKR.HYGL........NT.NLL....V
A5KRX3_9BACT/16-207             LKLL..YRYRFLNRIHIQTLLNHKD........KRRIISWLKDL.RDRQYV.DWHYD.....RT..DF.....IA.KSQPGIYYLSLNG......IRYL............RSLNE.........Y......PNE.........ELRKRYKEPTRTK......A.FIN.HCLLMADCCVALE.AKS.SD........E..LQYVS.....VLPSDYTY..PD.S......EYYFL..N..E.IKPQLFFSKQQGN.......QTTSYLLESFELTLPRYQ......FRKRIKDYIN.FMNEW........ND.TNG..........P.KPI....V
A5KSE9_9BACT/20-208             LELL..YKFRFGSNDLFAQYFGKKDR........SFVYKRLSIL.LEQGLIGKRFDS.....SY.........RL.LGKPAAYYLTPDG......VRSL............QGRRD.........P......KKPKIN....IKAIYKDK...TVSE......Q.FVA.HSLELFAISNKLKTQYG.SDL...L.FFT..KSHMN.....NEKYDY..................F..P..R.PLPDAYIRLKSSD.........KHFFLDVFHDNEPHFV......AKRRARQYIK.YDEDAE......WSV.TET..........D.LPV....I
C3DCG9_BACTU/11-181             VEWV..NLHGFVLAEQVQEFFGLGK.........TVVYRRLKEL.VEQGVL.KRERI.....L.............YDYGNVYWVTKDG......VELC............E.............S......EM............AAGK...KPSV......N.NFV.HDKKLVDLSVQLLKKYE.GSS...W..IT..ARQIK.....SRLVKKAS..EK.D......KFKAL..A..M.RVADGILIVNEKK...........YAVELELSLKNRTR......VKQIISDYAE.RIA..............KG..........Q.YVS....V
C3BDL4_BACMY/14-230             LVNI..YTHLFVDVEYVMMRHYAGYN.......KRSVYNRLRKL.EMANYI.KSEYLP..VPTIRGQQ.....RSNVRPKKVYTLTKKG......VDTV............RDLRG.........D......VR...........WKAKW..SVRAP......H.FVY.HSIMLAHVECAMT.HAS.KKQ...D..AR.ILREWI.....SEVLGTFK..YT.NSR.KKSKKEGA..G..I.IRPDGVAIIGNKRN.VS...ANAILFLEMERSFSTKEV......LIEKITRYNE.FMRQHK.....MEEYVK.HAGI...SYPVG.QCS....L
C3DAX8_BACTU/18-228             LMDI..HTHIYLDFEYIRMKNYPNHKE..KS.....VYARLAKL.EKENYI.KSERH.....PV.ASIRGKRRRS.GNGSNIYTLDKYG......VEMV............RELRG.........E......VH...........WNYKW..SNRVA......T.FVY.HSLMLAHVECAML.EQS.KAD..IP..IG..IKEWI.....NEARGTFQ..YD.K......NK..S..A..V.IRPDGLAVIGLKN...RI.EGNYGLFLEMERTYGTKEV......IEKKLRRYND.FLSREE......SVK.KYDRY.....AGLT.YPIEKWRL
C3IX13_BACTU/11-221             LMDI..HNHIYVDMEYITEKVYPNHKK..KS.....VYYRLNRL.VQEKYL.KNELLPIPVSRN.QVR.....KS.GRPQNVYTLAAKG......VETV............CGLRG.........S......VHW..........KSSWS...QRSA......S.FVY.HSLMLAKIECAMTLISK.REE...R..LE..LKEWI.....NEPRATFQ..Y.........AKGKN..R..V.IRPDGVAVIGLKEA.ID...KNIGVFMEMERSYGSKEV......LEKKIIRYND.FMTQEG......KKA.DYRTHAG.MGYEIP.IWR....L
C2RX52_BACCE/14-224             LMSL..HTHIYLDIEYIHQKVYVDYTK..KS.....VTNRLYKL.EQAGYI.RYEYL.....PVTSPRNQ.KRKF.AKPQRIYTLTPKG......VDMV............RGFRG.........E......VHW..........KASWS...QRAA......S.FVY.HSLMLAKVECAMTLASK.QEE...R..LE..LKEWI.....NEPRATFQ..Y.........TKGRN..R..V.IRPDGVGVIGLKEA.ID...KNIGVFMEMERSYGSKEV......LEKKIIRYND.FMTREE......KRK.EYRAHAG.IAYEVP.IWR....L
A1BZ85_BACCE/27-218             FTFL..YYKRYLTTRQITQLYSAFEGR..DF.SEDSVFTKLNRF.SK..YG.AILTK.....KIDKRD.....DS.ITRRATFSLKDRM......VDYL............QELGR.........I......PA...........GSSKR...RYSS......S.SSL.HTLCSREILVRTLLEVS.KKT...N..TNKILSELD.....IRSYHQKQ.KKT.E......IEDAG..L..L.LIPDEHISYKDKN...........IYIEMDMCKETNAT......LVEKVGKYIE.YAQKN............TK..........N.ITV....V
C3ICU8_BACTU/30-220             FTVL..YYKRALTTRQITQLYSAFEGR..EC....SEASIFTKLDRYSQYG.AMLTK.....RIDKRA.....DS.ITKRALFSLKEKT......IEFL............LEIGR.........I......PK............KSSK...RRYS......R.TTSLHTLCSREVMIRTLLATT.KKT...K..TN..EVLYE.....LDIRSFYQ..KK.N......IKIED..NQLA.LIPDEHISYQDKN...........IHIEMDMCKETNST......LVEKVEKYIE.YAKETN............E..........D.VTV....V
B3ZY63_BACCE/27-217             FTVL..YYKRALTTRQITTLYSAFERR..EC.SE...ASIFTKLDRYSQYG.AILTK.....KIDKRE.....DS.ITKRASFSLKEKA......IEFL............QKIGK.........L......PP............NVSK...KRYS......RVITL.HTLCAREVFVRTL.LAI.TKK...T...F..SNEIL.....NELDIRSY..YL.KNN..MTIQETQ..L..P.LIPDEHISYHNKN...........IYIEMDMCKETNAT......LVGKVGKYVE.YAQKT............DE..........N.VTV....V
E3ICI0_GEOS0/17-227             LAYL..FYYRGMTALQLSQMYYESEEP.FPT.QKSSVHNYLSKL.KKQNLV.ASKK.......LEGNI.....RP.GS...IYYLTTKG......FEVVKEMLNIDAGATEN...GFILLNERNGI.......PTQS......DLPYSLY...QPPK......Q.QIS.HHLLLIDFFIRLR.IHF.SEE.......E..SVDHR.....LSMYCSTP..YT.Y......NN.MD..S..K.IRPDAEIILPNGD..........AYWIEVDRATESHSQ......LMAKFQNYKN.FLSYLK......KNN.LPI..........P.FKG....I
C6J6Z3_9BACL/10-201             LALI..YRYGPMTAKQAAIVLNYRL....PT.....LYAMASQL.NRQGLI.RSIPL.....P...FL.....R...LNHVGYGLTAQG......AKTA............ALLAG.........E......EDG..........FRSKA..WEKLP......M.QLE.HVYGTNAFFVSLI.EHS.LHH...K..GE.GITEWQ.....STREAAEQ..YA.HF....KESGKK..T..MLLRPDGLCTYVLPG...R...GRLVLHVEYDTGSENQWK......LQDKLWLYGR.VLSAA.........W.RSV..........A.AVH....V
C7Q8H2_CATAD/62-260             LASL..NEFRLLSGSQLRRLHCPGGEI..ST.QARKTRAIMRRL.TELGVV.ARAER.....GV.GGI.....RS.GSEGYVFGLSGLG......HAVL............DRDQP.........GA....RRH............RSAI...ESKS......T.FTA.HILACSELMCQLV.EHS.RAG...G..CT..IEELR.....AEPGCWRW..FS.S......QSGGR..R..P.LKPDAYVRLTVDD.......FDLAAFIEIDLATESLPT......IASKCAVYLD.YWRSGA......EQR.VAG..........F.FPR....V
C9Z8H5_STRSW/21-220             LESL..RAHRLLGTAQIRRLHFAEGHATVTA.ASGATMRVLVRL.ESHGLV.ARLTR.....RI.GGV.....RS.GSSGIVWQLASTG......ERLL............RTVHG.........E......KK............RRRY..VEPSP......A.FTA.HTLAVAELAVQLH.EYA.GQG...V..IE..LLNVE.....TEPSCWRS..FV.N......PHGTL..E..W.LKPDLYAVTASGD.......YEDHWFLEADRATEHPTV......VVRKAKTYQR.YAATGA......HQA.RHG..........L.FPA....V
C0E5J5_9CORY/37-239             MDFL..HQHRFATTKHIARLLRPNFAS..ESSAIRQTARLMKHL.ASSSLV.AHLKR.....RI.GGA.....RA.GSTSSIWHLTEAG......QRFIYL........TQTGHTS.........Q......VK............RLRI..AEPSW......A.FLA.HTLAITELRILTE.ETC.RQH...P..IT..ITTIE.....TEPNCWRS..HL.G......HTGQP..K..W.VKPDLALITRAGG...F...HD.HWWCEVDLATECPAR......IHRKTDTYLR.HLYCGT......EQT.KRG..........T.FPV....V
D0L6G0_GORB4/81-278             LRSV..DEHRFMTARQIETLHVASVAA..DA.RGRVTRRILARL.RGLRVL.DTLDR.....RI.GGA.....RA.GSRGFIYHVGVAG......DRLL............TGARR.........G......SS............RLRY...EPTT......R.FVD.HRLAIADAHIALT.VAS.RTG...R..FE..LADGA.....VEPGSWRT..YT.G......IGAAR..R..T.LKPDLFAETASDD...D...HVTAWLIEIDLGSEHIPT......LLTKCREYEA.YRQTGI......EQD.RHG..........G.FPL....V
C8X7Q8_NAKMY/2-208              LTLI..HDHKFLTTRQLQALAFTHHAS..ELSAARTTRRVLQRL.HRERLL.ASLPR.....RV.GGM.....YG.GAENPTWHLAPTG......YRLH............YLASG.........G......ADDE........LPRRIR...EPSE......R.TVK.HCLAVADARIAVE.ETA.RET..GD..VL..VVRIV.....TEPDNWRR..YT.D......SMGTT..E..V.LKPDLELVTRTSD...EHGHYEDRWFLEVDLSTEHPPV......IVRQCQQYEA.YRRTGQ......EQD.RTG..........V.FPL....V
Q2JEK1_FRASC/26-223             LYDV..GKVRVLSGAQLTRLHFHDLTA..TS.RDRTRRGVLARL.AGHDLV.APLDR.....AV.GGA.....RS.GSAGYVYALGVAG......QRAL............PLLHA.........DAVGLPTRA............RRPW...TPGQ......S.FLK.HTLAISELYVQLV.EAE.RAG...R..LT..LTRFA.....AEAGAWWP.............DGAG..G..L.VKPDASACVAFGD.......VEDSWLVEVDRATESPET......LYRKLRRYVD.FAGAG.......QLG.PDG..........V.TPR....V
B6V2L8_BPSP1/34-230             IRLLIDNNRRILRRDQIEVLY.PEFPS..SD....YLNKRLKLL.YDKHVI.DRIYP.....AV.EPG.....KG.SSKQHI.CLDRAG......SILL............GLENY.........S......KPI.........STKNGV...KSLP......L.GWE.HKVKLNDYECLIK.KTV.SEL...G..GK..VLLYQ.....TEKALTF................GD..T..K.IIPDIFFLISCNK.......KGYMYFVEVDLGTEDLPY......VKKKIDSYMK.YYASKAW....IREK.WAGVF.....GSPV.FPR....V
D3FAT2_CONWI/32-222             VVTL..FEQRVLRTDQMAVLFFSSVRR..A.......QDRMLFL.YRHRVV.DRFYP.....A..APR.....GR.GKPQAHWLLDDAG......AHIV............AACLD........VD......RKAL.......HWERRSD...WGAH......R.HLA.HRLGVNGFVTGLV.AATLKAP...G..VG..VARWH.....GPRAVARV..I.........PGGLT..E..K.PIPDAGFQLSTAE...G...RV.ECLLEWDRGTESASV......LSEKLHRYRR....AS.......QDA.RGG..........P.VAN....V
A4X6D9_SALTO/23-216             LGWL..YDHSVLTSFQIAHALFPSLNY.........AQRRLTQL.TELSLL.ERFRP.....F...RL.....QG.GSHPYHYALAHTG......ALVV............AATRG.........D......EPPRRT....ASTTRLHR...IATS......R.NLD.HRLGINQFFTDLA.AHE.RIH...P..TA..RLHHW.....WPGTRLNR..FF.N......PPGTTAYG..M.VQADALGVWSEHG.......QTTVWYLEHDQGTEALGV......LVEKLAGYSN.LVRRG............GP..........A.WPV....L
A4X414_SALTO/20-220             LGWL..YDHGVLTSSQIAQALFPSLDF.........CQRRLRTL.YRLRLV.ARFRP.....Q...RA.....DG.GSYPYHYVIDQLG......AEVV............AASRD.........E......RPPRRD....HAWVERRR...WTST......R.SLS.HRLGVNGFLTDLV.GHA.RTH...P.DTG..LMEWL.....PEVACQRAGTFT.SRQDPGLVRAYQ..P..R.VRPDGYGRWADGG.......VEVPFFVEHDTGAEQLSI......LAGKVDGYRE.LFGTI............GR..........A.WPV....L
D9T7V3_MICAI/26-228             FGWL..YDHGVLTTDQIAAALFPSLDF..TQ.......RRLRRL.TLLRAV.DRFRP.....N...KA.....DG.GSYPYHYVLDQLGYDHVHAQRGL............PRGRR.........D......QA............RRRKQ.SLTSR......P.DLP.HLLGANQVFIDLA.AHA.RTH..PD..TD..LVRWQPASAYHEPGSLYR..AG.GDP.QIIIAGAT..G..F.PRPDGAGVWTEDG.......RSVPFFLEYDTSGENLQV......LIDKVIKYER.LYMMS............TW..........A.WPV....L
E8S2G0_MICSL/24-209             LHLL..DDHHVLTTDQIHQLFFLAR.........RTCQIRLSEL.YGLGLL.DRFRF........ART.....GG.GSQPWHWTLGHNG......HRFQAAAH....ERPEPTARA.........S......RQ............AVQR...VSAS......P.TLT.HLLTVNEFFVRLK.THT.RRH...P.EAR..LDRWW.....SERTTTRQ..F................R..T.ITADGHGIWTAAG.......ASVGFWLEADTGTEPLGR......LTGKLDRYAT.LTRRV............GI..........R.YPV....L
D9T2Q6_MICAI/29-219             LGLL..AEHYLLSTDQITNAFFDTR.........RTAQRRLTIL.HRLDVL.HRFGR.....S...GA.....HG.RYGSLLYTLGPVG......LQLH............PTTYH.........D......PNGLGGKAPRSSLERAKR...IAAS......G.QVN.HLLGVNQFFTDLI.ATA.RHT..PD..AL..LSRWW.....SEQHATTV..Y............AQ..A..G.IRPDGHGVWTVGG.......TSTGFFLEHDNDTENLAR......VVAKLRGYER.LTTFG.............P..........R.YPV....L
D9T0Y5_MICAI/1-197              MRWL..AEHYVLSTDQITTALFPSRR.........SARLRLAQL.HQMEAV.SRFAD..........V.....TT.GSGQYLYTLGPLG......TVVHPTQFNDPNHAGVRAPRT.........S......ID............RTER...IIGS......R.RLP.HLLGTNQLFIDLL.GYA.RTD..EN..AR..LARWW.....SEQHTTAA..FA.AA...SYAAGSG..T..G.VQPDGHGIWHAGG.......RTVGFFLEHDNGTEPLGT......VLRKLRAYEQ.LARYG.............P..........R.YPV....L
D3Q517_STANL/29-218             IDAL..GRYKVLTKAQVARLFFDSES.........SARDRLSTL.VELDVI.TRYRS.................H.NRQAWRYTLAYWG......ACVHAVA......TNPD.AKT.................PTKK.....AVFDQATR...IMHS......A.HRG.HTESTNDFFTRLT.ACC.RHRADEG..WV..VERWL.....SSAESSLF..............FTN..T..K.PRPDGGATIHMDD.......RVLEFWFEHDTGTEPLHV......LADKIDAYDKEYDQPW...........RDN..........F.TPV....L
C7PYS8_CATAD/28-212             LRLL..AEHQVLTIGQLAVALFPDVR.........KCRSRVAVL.RALKLV.ETFRP.....PL...Q.....RG.SSQAHCVATARTL......DLLS............TDADG.........S......RL............RRRS...TYDAAAIALRP.DLG.HLRGVNEVFCQLL.GYA.RQT...P..GA.MLETWR.....SERATARA..L.............G..T..R.LRPDGFGRWRQND.......AKCEFFLEYDTGTEPHAR......LLAKLTGYAD.LAESA.............G..........VSCPV....L
C7Q1Z1_CATAD/20-201             LRLI..AEHRVLTSSQLTTAFFNHPS.........KARLRIGIL.RDAGLI.ETFRP.....P...........G.GRAALHCVATAKA......LKLL............GADRS.........A.....MPPAG.......KAQAATA...AALR......P.DLR.HLRGVNEFFCQLI.AYS.RRT..RG..AA..LEEWR.....SEWSTAAL..F.............P..G..R.VRADGFAHWRVGE.......QWCEFFFEYDTGSEPLHR......LVAKLDGYDD.LMHTA............DT..........C.CPV....L
A8L962_FRASN/45-232             TRML..HEHRVLTTHQIVELGWTGRR.........AANLRLLEL.YRWRVL.DRFQP.....LV.........PA.GLAPMHYILDVAG......AAVL............AHEDGLDPK.KIGYQ......HD............RAKG...IAHS......L.HLA.HRVAVNGMFTRLI.HHA.RQP...GAAGK..LTAWW.....PEERCARH..F.............G..D..I.VRPDAYGRWTTRG...G...ATVEWFLELDYGTEPLHR......VTAKLAAYHQ.LATST............RI..........A.TPI....L
Q2JC28_FRASC/45-231             ARMV..GEHRVLTTHQITRLGWTSQR.........SANIRLLGL.YRWRVL.DRFQP.....LV.........SR.GLAPMHYILDVAG......AAVL............AHEDDLDPK.KIGYQ......HD............RAKG...IAHS......L.HLA.HRVVVNEMFTHLV.HHA.RQP...DSAAR..LTAWW.....SQERCAFA..F.............G..D..I.VRPDAYGRWAERG.......VTLDWFLELDQGTEATRR......LAVKLLDYHK.LATTT............RI..........T.TPV....L
Q2J9G6_FRASC/45-231             TRMI..HEHRVLTTHQIAQLGWTSRR.........AANIRLLEL.YRWRVL.DRFQP.....L....A.....VS.GLAPMHYVLDVAG......AAVLAYE.....DGVDPKKTG........YQ......HD............RAKG...IAHS......L.HLA.HRVAVNEVFTSLV.YHA.RQP...DTAGT..LTAWW.....SQERCAEH..F.............G..D..I.VRPDAYGRWTERG.......AEVEWFLELDYGTEAMRR......LAAKLLDYQQ.LATAT............RI..........T.TPV....L
A8L5H0_FRASN/42-230             ARLL..YEHRVLTTHQLVQVGWPTR.........RTANERLLQL.YRWRVV.DRFQP......L.SPL.....GE.GMPPAHYVCDVAG......AAIL............AAEDGIDL..AATGY......RH...........DRALG...VAYW......P.QLA.HRVAVNGFFTHLI.AHA.RKPN.PP..GT..LTAWW.....SEARTRRA..F.............G..D..I.VRPDAYGRWTSRG.......GDLEWFLELDWATEPYAR......LAAKIDKYGR.LATAT............GI..........T.TPV....L
A8L858_FRASN/43-231             TRLA..HEHRVLTTHQIVEVGWSTQ.........RAANRRLLEL.YRWRVL.DRFQP.....LV..PV.....GQ.GQPPAHYVCDIAG......ASVL............AAEDSIEL..KETGY......RH...........TRAMA...IAHS......L.RLA.HTVAVNGFFTALI.AHA.RRPT.PP..GT..LTAWW.....SETRCQQA..F.............G..D..L.VRPDAYGRWTSAR.......GEIEWFLELDWATEQLNR......LALKIGDYGR.LAAAT............RI..........S.TPV....L
C7QG98_CATAD/49-242             LHAL..REHQVLTGPQIARIAFDGPRI.........ANRRLAILANELRVI.ERFRP.....L..........RAIGSAPEHYVLGAHG......AQVL............AAEAGVTIK.QLGYH......RS............RSLG...VAYS......P.RLA.HTVGVNEVYSHLA.AAS.RIGPDAD..GE..LVSWW.....SELTCFHL..Y.............G..D..L.ARPDAFGRWKAPA..PRGKLRTAEFFLEYDTGSENLER......VVGKLDGYAR.LAAVT............GI..........D.TPV....L
A8L0V2_FRASN/23-211             FAML..HEHRVLTRHQLTRLAFTGD.........RMTRLRLATL.TRLQTV.DRLRP.....YY.GQ......GR.GTGPYHYALGPLG......AAIL............AAERGLSVA.ELGYR......RD............KLHA...WANS......P.RLG.HHLGVNAVFTALV.HAS.RPR..PD..HE.GLTVWW.....SEQRAAAL...............WG..Q..W.IRPDGYGTWQTAR.......RRLDFFVEFDTGSESLSQ......VARKIPGYTR.LAASS............GL..........T.SPV....L
A8LB37_FRASN/37-222             LAML..AEHQILTTRQIALLCFSGD.........RTARARLALL.AELRAV.DRVRP.....LR.GD.........LATPYHYTLGPAG......AQVL............AAQAALPV..SEFYR......RD............RGLS...LIYS......R.LLD.HTVGANGLFVAFA.HAS.RPR...P..ANDGLVLWW.....SEKRAVTM...............WR..Q..W.VRPDGFGAWYHQG.......RRLDFFVEFDTGTEPLTR......VAGKIPGYAK.LAVSS............GM..........V.SPV....L
D3FEB7_CONWI/60-249             VIDC..YEHTTLTTDQLTRLHFRHPN.........TARERLDVL.YRLRML.DRFRP.....EV..RL.....GE.GSAPYHWILDEAG......AHVV............ADELGL......DREQL..RWRH............ATAA..RVAVS......S.KLD.HHVATNEFFVRLA.VEL.RAA...G..GS..LHEWY.....GEKTTSRL..L.............G..G..I.VTPDGYGVLHLPD...R...APLHLLLEVDRGTEPLRR......IREKIDRYSKALPRS..........E.LAS..........V.APL....V
Q82RH5_STRAW/26-234             LAGL..AQHRIATTSQMRRMLRPDGTR..QL.....MSRVLNRL.RSDGFV.DCTVL.........PD.....AN.RTRTNAWYLTQEG......ARLT............RDLPV.........L......RGRP.......PYPISSM...TAAS......L.KTP.HTLAVVRAHLAFA.ADA.RRL...G..HE..HGPWD.....WTPEVSHS..I...........GEG..E..R.IVADAVMYYTVVESEHR...RKLRAFVEVDRSTMSSER......LAVKLIEYAR.LFQYEAQPVGRRRQA...SVGPAWLRWYPV.FPR....V
E6TVE2_BACCJ/10-186             LQSI..ANLRFMNSQQIHTLHGYNGKY..GE...RVTRRKLNEL.EKKKML.KSFQP.....S.............AYEKKIYYLTKTA......AKEL............SHFTG.........I......EG.............IKT...LKKN......D.KSM.HQVMVSEIYIQLQ.KCR..I.......GQ..VKRYK.....VEDKI...................H..E..D.LLVDAFVEYRLRS..TG...KKKLIFVEADRGTESAVI......IEEKFKKYDY.LYRSHK......FQN.MYG..........I.FPD....I
E8STP8_GEOS2/13-168             LYAL..NSLQALSRSQIQHMFDLGSK........RNANRILQGL.REYTHT.KRI.......................GEDVYYLNKAG......AEMV............GGEVT.........V......R......................RN......S.PLE.HIVMRNDIYIFYH.YPH................DWK.....AEAKTRWK............EGGKE..Y..S.VVSDARFTYQGK...........MCFLEVDI.TQKMVE......NKRKIERYAY.LFRFIQ........R.QQL..........G.EPV....L
B0FY00_BACTU/16-172             LSSL..NKLEFASRRQLQAIHALGS........IRNANRILKDL.RQYCHV.TSHN......................REYVYYLNKKG......LALL............GLNPD.........E......RK.....................KK......H.QLE.HILLRNEAWMW................LG..FPDWK.....TEQTIKFR..YQ.N.........EE..K..I.IVPDAYYLVDQVP...........HFVEIDR.LQHMKT......NEEKIQYYSL.IAKL........YKK.QKD..........L.VPN....I
Q81EP7_BACCR/16-174             LTSI..RKLKFATRRHLMAVHDMGGI........RNANRILKDL.S..PYV.NNTVY....................QKEYVYYLNKKG......RELF............D..................................DTEK...IVPN......S.RLA.HSLMRNEAWLYLF.CPD................DWQ.....IEAPIRYK..V.........ND.KK..K..T.IIPDVKFRDEEGT..........LNAVEIDR.TQMMNV......NAEKMSRYRE.FSLYY.......KNK.YNG..........K.IPL....I
Q6HJ44_BACHK/16-174             LATI..RKLQFATRRHLMSVHNMGGI........RNANRILGDL.K..PYV.NKTM..................Q.G.KEYVYYLNKEG......HAMF............GDD..................................GK...VVSR......G.KLA.HALLRNEAWLHLF.CPD................DWQ.....IETDI..R..YI.K......NK.EK..M..K.IVPDVKFRDEENI..........LHAVEVDR.SQKMKV......NEEKIKKYEE.FTQIY.......KQK.HNG..........K.MPV....I
Q3HKZ6_9CAUD/16-173             LATI..RKLQFATRRHLMSIHEMGGI........RNANRILKDL.S......IYTSK.....VV............YNKEHVYYLNQSG......HKLF............G...................................EGK...VVHH......G.KVT.HALLRNEAWLNLY.CPD................DWQ.....VETEIKYI...K.D......N..KK..K..K.IIPDVKFRDEDRI..........LHAVEIDR.TQKMIV......NDEKLKKYEE.LTQIY.......KQK.HNG..........K.VPV....I
#=GC seq_cons                   Lthl..tcHphLoscQltplhhsstt.........tspppLpcL.pphphl.cphp.................ts.uptshhYhLsttG......tchl............st.ts.........t......tt............pttt...hsss......t.pls.HplslschastLh.tts.+pt...s..hp..ltcWh.....sE.psttt..h.............t..p..h.lpPDuhhthptss.......tthtaalEhDpuTEshtp......ltpKlppYtc.hhptt............tt..........s.hPl....l
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