# STOCKHOLM 1.0
#=GF ID   Dehydratase_hem
#=GF AC   PF13816.1
#=GF DE   Haem-containing dehydratase
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:Q76K71
#=GF GA   25.00 25.00;
#=GF TC   25.90 25.40;
#=GF NC   24.80 24.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16233624
#=GF RT   Aldoxime dehydratase co-existing with nitrile hydratase and
#=GF RT   amidase in the iron-type nitrile hydratase-producer Rhodococcus
#=GF RT   sp. N-771.
#=GF RA   Kato Y, Yoshida S, Xie SX, Asano Y;
#=GF RL   J Biosci Bioeng. 2004;97:250-259.
#=GF RN   [2]
#=GF RM   10651646
#=GF RT   Novel heme-containing lyase, phenylacetaldoxime dehydratase from
#=GF RT   Bacillus sp. strain OxB-1: purification, characterization, and
#=GF RT   molecular cloning of the gene.
#=GF RA   Kato Y, Nakamura K, Sakiyama H, Mayhew SG, Asano Y;
#=GF RL   Biochemistry. 2000;39:800-809.
#=GF RN   [3]
#=GF RM   19740758
#=GF RT   X-ray crystal structure of michaelis complex of aldoxime
#=GF RT   dehydratase.
#=GF RA   Sawai H, Sugimoto H, Kato Y, Asano Y, Shiro Y, Aono S;
#=GF RL   J Biol Chem. 2009;284:32089-32096.
#=GF DR   INTERPRO; IPR025702;
#=GF CC   This family includes aldoxime dehydratase, EC:4.99.1.5. This is
#=GF CC   a haem-containing enzyme, which catalyses the dehydration of
#=GF CC   aldoximes to their corresponding nitrile [1]. It also includes
#=GF CC   phenylacetaldoxime dehydratase, EC:4.99.1.7. This
#=GF CC   haem-containing enzyme catalyses the dehydration of
#=GF CC   Z-phenylacetaldoxime to phenylacetonitrile [2]. The enzyme forms
#=GF CC   an elliptic beta barrel, composed of eight beta-strands, flanked
#=GF CC   by alpha-helices [3].
#=GF SQ   33
#=GS C7ZFH7_NECH7/15-326   AC C7ZFH7.1
#=GS Q2WG72_GIBZA/14-329   AC Q2WG72.1
#=GS Q0CF39_ASPTN/14-333   AC Q0CF39.1
#=GS Q5B890_EMENI/325-643  AC Q5B890.1
#=GS B8NMG3_ASPFN/16-332   AC B8NMG3.1
#=GS B1KM99_SHEWM/29-326   AC B1KM99.1
#=GS A1R5Y5_ARTAT/54-350   AC A1R5Y5.1
#=GS A5EKU7_BRASB/43-335   AC A5EKU7.1
#=GS A5V4Y9_SPHWW/43-337   AC A5V4Y9.1
#=GS C5CKL2_VARPS/43-346   AC C5CKL2.1
#=GS C0ZVD3_RHOE4/60-360   AC C0ZVD3.1
#=GS Q6FBU3_ACIAD/43-342   AC Q6FBU3.1
#=GS C3KC36_PSEFS/43-343   AC C3KC36.1
#=GS Q1BN36_BURCA/43-343   AC Q1BN36.1
#=GS F0QD95_ACIAP/43-343   AC F0QD95.1
#=GS Q4VYU2_RHIRD/43-343   AC Q4VYU2.1
#=GS Q500U2_PSEU2/43-341   AC Q500U2.1
#=GS B2WMJ9_PYRTR/6-318    AC B2WMJ9.1
#=GS D4DHU0_TRIVH/55-363   AC D4DHU0.1
#=GS C5FDU1_ARTOC/81-390   AC C5FDU1.1
#=GS C5G803_AJEDR/44-352   AC C5G803.1
#=GS C1H9S7_PARBA/44-352   AC C1H9S7.1
#=GS C9STN6_VERA1/45-354   AC C9STN6.1
#=GS A7IFL4_XANP2/39-340   AC A7IFL4.1
#=GS Q0U2P3_PHANO/36-345   AC Q0U2P3.2
#=GS C7Z148_NECH7/36-347   AC C7Z148.1
#=GS C9SXX8_VERA1/36-349   AC C9SXX8.1
#=GS Q0C7P1_ASPTN/35-346   AC Q0C7P1.1
#=GS B8NPL1_ASPFN/36-350   AC B8NPL1.1
#=GS A1CY61_NEOFI/6-331    AC A1CY61.1
#=GS A1CFW9_ASPCL/35-358   AC A1CFW9.1
#=GS C6WDR0_ACTMD/39-337   AC C6WDR0.1
#=GS OXD_BACSX/28-329      AC P82604.2
C7ZFH7_NECH7/15-326              YGIYGIQYQGQSP..........SGRQLDLIQKFDELISGQAHL.....DRITVPGNDGFATQIWLSYWW.PDSHTGWWSKPAVKDFWDNLP....EDAGMWREVLTVSPSRVQNACTA.ELKNGLNGLGN..MEPFSDKIGYWGCIRHRIPDANLD.....DKLASSLEEMPSRVPETSDIRPGRTLVTD..FPDNICFLVEGQDHTRMSTREKDLWFEEFDELVTGWMEHLGKDTTANGLFDVRMGHVSDCGTFKDTGPIN..........LNHNRKIEMFYWMDISKFERVGRVHRGHVKLRKRWMETYGPGGEMGDGVGKINLWEETSIMKGSDIVAEYVGCREGTGF
Q2WG72_GIBZA/14-329              VSVFGCQYHSEAP..........SVEKTELIGRFDKLIDSAAIHVEHL.EQN......DVPSKIWMSYWESPQKFKQWWEKDDTASFWASLP....DDAGFWRETFSLPATRAMYEGTG.KDAYGFGHCGS..LIPLTTKTGYWGAYRSRMTPDF.....EGDTFSSPIPTYADQSVPADKIRPGRVRITD..FPDNLCMVVEGQHYADMGEREREYWNENFDGLTKQWVTNVVTAGHEQGMVIARACHGFAGEKKLGATNGPVN...GIFPGLDYVHQAQILIWQDISKMEHIGRYDQTHVKLRRDFMKAYGPGGEM..EGGDLLLWVDLGILKKDEIDAEYVGCYESTGF
Q0CF39_ASPTN/14-333              LAVFGCQYHGLQP..........NASKSALASEFNDLIQEASVPVEVMEHDD..FELEDCRSKVWMGYWKTPEDYRAWWCSPKVAAFWSKLP....DNAGFWRESLRFAHSRVLFETNQ.KAPNGFAHVGS..FEPLVEKTGYWGSYRDRLEDATELDKLSTPIQPPVLPPRKSTK....NIRLGRVSMEN..FPDNLCCVVEGQDYSAMGSVEHDYWMENFHNLTTEWLTTALKAPIEDGVVSARLCHDPQSGSMDKAPAVPFFNAA.....LNAKRKLQLLYFLDLSCMERIGRKYKSHVQLRRKFMQAYGPKGDM..EGGDLLLWVDLGVLKADDISAEYIGCHEGTGF
Q5B890_EMENI/325-643             LAVFGIQRLEANN..........A...NLLIDAFNAVFTTNVPIIEHL.EQD.....DPTPTRLWLTYWPSRAVFETWWNSGPVSSFWSSLP....DDAGVYREIMTVPPGRTQHGTNATERVNGMANLGI..FEDISEKSGYWGCYYDRMADVTRERRNDIRSAASKTPSQSSSALTGEKILRGRVNLNAGYLPDNIAFVVEGQDHSSISSEERSHWFEHFDAAVTRWIINLVAAGPEHGVLNARLCYEPVCGTYRDADGAPSA........LNYNRKIQLFYFQDMESMERIGRENKGHVNLRREFMASYAPDGPMGRLPGKLCLWVEASILKSKEIEAEYVGCVKGTGL
B8NMG3_ASPFN/16-332              YTLFGVQQPDDVQ..........SPATENLIRTFSHLITGANCHLDQV.TQDGIVSPGIGKTRIWIATWKSIADFEAWWESDSVIKFWSSLP....PDAGMWREFVKVPYGRSQYKATQNRQDGQGVHFAH....KPTEKNGYWGWIRDSIRELSKENRMDSPLLVPPIPERKASLKEKT...LGRVTFNG..FPDNLCFNLERQDLSEMTGAERGVWFDQFDQAACKWMDDLAHAAPEAGILTSRMCYDERLGTYKEGDSEF..........HKYNRKVELFYFMDLRSMERAGRSNKGHVALRNNILKTYGPGGIMS.ECGKVALWVQTNILKAPEIDAEYVGCVPGTGS
B1KM99_SHEWM/29-326              CGLFAIQGQHSAPL........DDWAKKA.........FTGEFSPKLL.EQGMFTDKAGITNYLYIAYWFASD.YKTWWQQSAANSWWASPL.LDEGDISVWREVFTMPHQRFETLHSSENA.HGAARLSP.SLEGPMMEHGYSGAARDRIPCSSSQDIKN.......DNSIWEHLQVNVENKSNRIKLS..PP.KNMCVIRSGQDWTHCEEDEKEYYLTNVHTVLKKGMDYLSNNPVKTHCASMRFITKTDG....NWCS............V..EQTFGLGYGNDIYAFENWAKSHPTHIAIFDRFMGMV.EKYN...VDLKLQLWHEVTLIPEQDCEFEYINCHGQTGL
A1R5Y5_ARTAT/54-350              CAFLGVQSRAPLSH........EAKVASAGMWEL....CANEDGPMSR.EHAVHTDEQGFDNQVIIAYWDDVDAYGRWFKKHRDALIGAGLE.P..SDYGRWIEAVTPEARGFETLYSSNTFPEGAARMATGGFTGEIQEHGYWGSMRDRLPIAQTDALEP.........VGDPVV....PRNPGIVRVE..PH.DNLAVIRSGQDWSLCDDAERASYFSHVEPQLKAGMDFLTTEGASIGCYANRYMTSSDG....N.GN............V.LEQSFGLSFWHSLEDMERWAESHPTHVAIFRSAMTFL.QA.N...AGARLRLSHEVAVVSRDQQYYEYNNCHAGTGM
A5EKU7_BRASB/43-335              MAYFGVQYRAE............TPAAASTADFMVL..VSRADGPSHW.DLAHYVDQAGFANDVFVAYWDDVVRFDSWFEPARAA..WTGPG...AEGGGRFIEVLRPAVERYETLFSSLGRPEGIAVIAE.GMSGEVLEHAYWGGMRDRIPLSQTSEMRS.........LGKPTLVQDGP....RLRVI..AQ.DNLCMIRSGQDWSDTDAAERRMYLDDVEPVLREGMDFLRDQGLSIGCYANRYMRLRGA....D.GA............L.TEKSYGQSWWQSLSALERWAESHPTHVRIFGAAMKYL.SSLG...PAARLRLYHEVTVAAADEQFFEYRGCHAKTGM
A5V4Y9_SPHWW/43-337              MASYGVQGRES.GD........VAAALAHVRALR....ATLDADVRHV.DLARYVDEAGYDTLVLQPYWTDPEAFRRWEARADVAALLAAET.....GLGHFREILTPTVERLETLYSTEDEMEGLGRALE.RRSPPVQEHAYWGSARDRFPIAQTDALEP.........AGQLGFAADG...AGRVTVR..GH.DNIAIIRSGQDWGPTGGEERRLYLAEIEPVLRAGMDFLRDRGGECGCYLNRYMRIVDM....D.GA............P.QEKSFGWSYWRSLGDMENWSEAHPSHLAIFGTFMRIV.QQLN...FDLKLRLWHEVYVVTPDQQLYDYRNCHPDTGF
C5CKL2_VARPS/43-346              MGYFGVQSRGA.GM........QGRACAALMKIAAG..FALPDGPGHH.DFAHHVDAAGCDNMVAIAYWNDPAAHARWCTAPEVDAWWRSDE.RLADGLGYFREIVAPRAEHFETMFNTPDRLEGVGVVMG.GVSGELQEHGYWGSMRDRIPLSQTDAMAP.........SGTRAVIAGAPAPGQRVRIA..GH.ENIAMIRSGQEWADTTGQERALYLGEMEPVLREGMDFLRDQGLHIGCYSNRYMQHLDA....K.GA............P.LEKSFGLSFWHSLADMERWAESHPTHVAIFGSFMRYV.QALN...FQLQLRVYHEVSVLKADEQSYEYINCHAGSGL
C0ZVD3_RHOE4/60-360              MGYLGVQFRGE.DQ........RSAALQSMRDIVAG..FDLPDGPAHH.DLTHHVDNQGYENLIVVGYWKDVSSQHRWSTSAPVASWWESED.RLSDGLGFFREIVAPRAEQFETLYAFQDDLPGVGAVMD.GVSGEINEHGYWGSMRERFPISQTDWMQA.........SGELRVVAGDPAAGGRVVVR..GH.DNIALIRSGQDWADAEADERSLYLDEILPTLQSGMDFLRDNGPAVGCYSNRFVRNIDI....D.GN............F.LDLSYNIGHWASLDQLERWSESHPTHLRIFTTFFRVA.EGLS......KLRLYHEVSVFDAADQLYEYINCHPGTGM
Q6FBU3_ACIAD/43-342              MAYFGVQFKSE..Q........KAIALKAMQHIVQS..FSLDNGPQNH.DITHHTDNQGYENYIVVGYWRDPGAYCRWFRSTEVSHWWDSDE.RLNDGIGYFREIVIPRADQFETLYAFKEDLPGVGAVMD.DISDDIQEHGYWGSARERFPISQTDRMLA.........NGELHIISGDPEKGGRVLVQ..GH.DNITLIRSGQDWVNADEKERELYFNEMLPSLQAGMDFLRDEGQALGCYSNRFVRNVDI....D.GN............L.LDIAYDIGYWRSLDKLERWAESHPTHLRIFTTFFKVV.TGLQ......NLRLYHEVSVSDAKNQVFEYINCHPQTGM
C3KC36_PSEFS/43-343              MAYLGVQYRGD.AQ........REPALQAMRHIVGS..FSLADGPQTY.DLTHHTDSSGFDNLIVVGYWKDPAAHCRWLRSPQVNDWWSSPD.RLGEGLGYFREITAPRTEQFETLYAFQENLPGVGAVMD.TTSGEIEEHGYWGSMRDRFPISQTDWMKP.........TSELQVIAGDPAQGGRVLVL..GH.DNLTLIRSGQDWADAEAEERSLYLDEILPTLQDGMDFLRDNGQPLGCYSNRFVRNIDL....D.GN............F.LDLSYNIGHWRSVEKLERWAESHPTHLRIFVTFFRVA.AGLK......KLRLYHEVSVSDAKSQVFEYISCHPQTGM
Q1BN36_BURCA/43-343              MGYFGVQYSGA.DK........RAAALAALRRIVAD..FGMQDGPNNF.DLTQHTDDQGYENLIAVGYWRDPAAYARWIASPALVEWWASDA.RLADGIGYFREIVAPRAEQFETLYAFTSDFPGVGAIMD.GVSGEIEEHGYWGSMRDRFPISQTDWMNA.........NGELRIVDGDPARGGRVVVL..AH.DNIALIRSGQDWRAAESDERRLYLEEIEPTLRSGMEFLRDNGKEVGCYSNRYVRSIDL....D.GN............L.LDESYNIGHWRSLDRLERWAESHPTHLRIFVTFFRVV.TGLS......KLRLYHEVSVFDAKHQVYEYVNCHPRTGL
F0QD95_ACIAP/43-343              MAYFGIQYQGE.AQ........KPRALAVLREWVAA..FGAPDGPLRH.DLTHHIDAQGYDNLIAVGYWRDPEAHRRWMQAPAQAGWWNAPE.RLQEGLGYFREVSAPRAEQFETLYAFQDALPGVGGVME.STSGDIQEHGYWGSMRDRFPASQVDRMQA.........RGTLLIAEGDPAHGGRVVVR..GH.DNIALIRSGQDWMEAEAEERRLYLEDIEPTLHAGMDFLRDQGAAVGCYSNRYVHNIDL....D.GR............R.LDQSYNIGHWRSVDLLERWAESHPTHLRIFGTFFKVA.AGLS......KLRLYHEVSVSDAASQHFEYIQCHPATGM
Q4VYU2_RHIRD/43-343              MGYFGIQYYGE.EK........KPEALAALRHIVSD..FSGVDGPMEY.DLTHHRDAQGYDNLIAVGYWRDPEAQQRWQSAPAVSGWWNSDD.RLAENIGYFREIVAPRAEQFETLYAFQDQFPGVGAVMD.GVSDEVEEHGYWGSMRDRFAASQTDWMSA.........TGNLEVISGDPRKGGRVVVR..GH.DNIALIRSGQDWADADGDERKLYLDEIEPTLRAGMDFLRDNGKGVGCYSNRYVQYIDL....D.GN............F.LEKSYNIGHWRSLDLLERWAESHPTHLRIFVTFFRVA.AGLS......KLRLYHEVSVFDARNQLFEYINCHPQTGM
Q500U2_PSEU2/43-341              MAYFGVQ.....SL........HPVGLPELAAITAW..FDSDSGPRYW.DSACCVDADGFHTCIAIAYWHDVDAFNRWRNSSGFLRWWQDPA.RETGPLGWFLEVVCPSTERFETLFSAPDVPEGVTHLAT.HMSEPIQEHAYWGSSRDRIPFAQTDALAG.........SSNPS..SADVLRAGRVRMS..GR.DNLCLIRSGQDWSSTTGQERDLYLNDIQPVLQTGMTFLRDEGATVGCLSCRFMQALDN....ESGE............P.LEKSFGLAWFDDLSNLERWAKTHPTHVAIFGGFMQYV.QTLN...FQVQLRLYHEIAVIPREAQYFEYLNCHPGSGL
B2WMJ9_PYRTR/6-318               MAIMGAQHACTIGA........DSAGISTIKEFVRD..APESLRPSFW.EVTSVVDKKGAYNVAVVAYWPSTNLHRDWQEKSGFNVWWQSSD.REKDGYGWFQEVLSPTVDRFETVFSNSEHPEGAANMQE.KISGEMEEHGYWGSMRDRLAAAQDDELKGTKWVDSGNAGNASHANGGS...SKRTRIA..GK.RNLCVIRSGQDWSDTLPEEHKLYLETIHPVLVKGMNFLRDEGRQTGCYAMNLWDVVDS....KSHE............VNQDRTFGLGYFDDLASLEDWSKSHQTHVNIFGGFLMYA.KKLN...NVLSLRLFHEIYVLEQDQQFFEYIGCHEESGM
D4DHU0_TRIVH/55-363              MAIIGAQYASAAGN........DGAAISKILEFVKSP.TDTEVRPSFW.ELASVTDANGSYNIAILAYWPSQETYESWNKVSNFRSWWEGLD.TENQQHGWFLEVFSPTTDGFETVASDEKVLEGAACMRE.KASGPILEHVYWGSMRDRMPICQTDAVPG........DTTSSAAQQISSTLRRRVQVP..GR.QNLVVIRSGQDWSNTPPEEHKLYIDTMQPPLIEGMTFLRDQGREIGCHSCRLMDIVDN....DTFE............VAKDRTFGLAYWDSLGSLEKWSREHPTHLNIFGTFLKYA.KRLD...NNVSLRLFHEVLVLKPEQQFFEYVGCHEKTGM
C5FDU1_ARTOC/81-390              MAIIGAQYSSAAEN........DGVAMSKVLEFMKNP.SDATAQPSFR.ELVSVTDPNGSYNIAVIAYWPCRESYERWSVASTFTDWWEGLV.VEDEHHGWFLEVFSPTIDRFETIISGNEVPEGIAHMRE.RVSGPLREHVYWGSMRDRLPISQTDAITG.......ESINEAVHQVGGNTLQRRVRVP..GK.HNLAIIRSGQDWSNTRPEERKLYIETIHPALVMGMDFLRDKGRDIGCYSCRLMDVVDT....DTFK............ADKDRTFGLAYFDDLGSLEKWSKEHQTHTAIFVGFLQYA.KKLE...NNISLRLFHEVLVLKPEQQFFEYLGCHEKTGM
C5G803_AJEDR/44-352              MAVVGAQYSTPTDE........DGLAMSTVSGFINNP.TAAGKKPSFW.ELASVTDNRGAYNIAVLAYWPDKGSYTEWATTSGFQTWWDTLD.PETQRHGWFLEVFSPTIDRFETVFSDNEVPEGAAHMRE.SVSGPLREHVYWGSMRDRLPIAQTDELVG........ESGNTANKPTNSVLRRRIRVG..GK.QNFAVIRSGQDWSNTRPEERKLYVETMHPVLTKGMDFLRDHGEDVGCYSCRFMDIVDP....VSHK............ADKERTFGLAFFDDLSSLEGWSKSHQTHINIFGGFLKYA.KSLD...NNISLRLFHEVLVLKPEQQLFEYLGCHENSGM
C1H9S7_PARBA/44-352              MAVIGAQYAASPEE........DGSAMSTLLGFIKDS.PSVEQKPSFW.ELASVTDTNGAYNIAVISYWPNKESYTEWGAASGFQNWWETLN.PEEQNHGWFLEVFFPTIDRFETVFSDTNVIEGVAHMRE.SVSGPIKEHVYWGSMRDRLPAGQTDALVG........ENGRTARKTTNSPLRRRIRVS..GM.KNLAIIRSGQDWSKTNPEERKLYLETMHPVLIKGMNFLRDQGDEVGCYSCRFMDIIDN....VSYK............ADKDRTFGLAFFDDLSSLEGWSKKHQTHLDIFGGFLKYA.KSLN...NIISLRLFHEVLVLKPEQQLFEYIGCHENSGM
C9STN6_VERA1/45-354              LAVVGAQYPSASRN........DGNAIKAVSSFIDL..SSPRSRPGFH.EVAAVTDNQGHFNIAVLLYWKSKANYDEWLATSGFGRWWDELT.PGTDQHGWFLEVFYPTIDRFETVIT.TEVPQGAANLRE.TMSGPIQEHVYWGSMRDRFPISQTDALVG....ETSHIHPRNETPAPPSATGRRV.VP..GK.KNLVVIRSGQDWSVAAPEERQLYLDTMHTVLVKGMDFLRDQGDQVGCFSCRFMEIVDP....VTQT............GGTDQTFGLAYFDSLASLEKWSKEHRTHLEIFAGFSKYA.KKLG...DSMSLRLFHEVLVLEPEQQRFEYIDCHEGTGM
A7IFL4_XANP2/39-340              CAYFGLQGQDLAWD...........EQKAFFDRLQT..SFGTDGPVAH.EIMRMHDETGAVNAILVAYWLDATAHARWERNSPFMAWFRDPA.RLEGTRGVWRETMHVPYDRHETIYSTPSYVIGLARTPG.ATRVPITTNGYFGAMRDRMPVSAIDTLES.........PLGAMPPRRAPDSHGRRLTA..AFPLNLISIRSGQYWEGAGNEQTADYIDNLQPKLMRGMAHLSSHPEQTGTLTLRIMTNLDA......EG............RPRAETSVHGYFLSMAHLEEWSRSHETHLDIYRHAIAMN.RLYK...EKREVFTWHEVFALLPG.AHAEYANCHGGTGL
Q0U2P3_PHANO/36-345              TAYIGVQQHIDDNE....AANSAAQAIQQVKKWLV.....QDDGPATHESFTVIEDDSTKDVAVWVCYWNDLEKHKSSMEKLSLSSIHSSLSSP...SIGLWRETFTSSVSRLETNYSGLDYLPGLARLPR.ADTVEHTLSAYWGAARDRIPDSAHDLFPR.........AAESPPSTTVTSGRGKH.LLGTNH.ANLVHIRSGQYWENCSQMEADAYEQKLEPTLRSGLQYLQQNPADTGAIALRYMQNADLPY..DPNA............RQKKESCGAGFFANLEDLERWAHTHQSHLKIYRGALAHY.KEFG...DLRKFRTWHEVSVIGESDATFEYVNCDLDPGV
C7Z148_NECH7/36-347              TAYIGIQKHSNDQA....TSDAQKEATSAIQAWLK.....GHHGPSAFESFTVIDGSDVEETSIWVSYWLEESKYKLSIEKLSLPSIYSSLSTPGRASIGIWREAFTTEVPRLETNYSGLDYLPGLARLPG.TSFPEHEFSAYWGAARDRIPSSAYDLFPQ.........SADTVPPTTVPRGIGQY.LTGTNA.ENIAHIRSGQFWENCGQEEADAYDSKLEPTLRSGLEYLWENSPDTGALGLRYLRNHDIDSPDE...............RLRKETCGAGFFTSLETLENWAKSHRSHLAIYRGAMAHY.KAFG...DRRKMRTWHEVSVLRGGDAKFEYLNCVPKTGV
C9SXX8_VERA1/36-349              TAYIGVQRHAADEP....CLRADAQIASAIRAWLE.....AGHGPAVFEAFAMIDGAEATDTSVWVCYWQDADKYDAALQALALPALFSRLETRDRESIGLWRECFATALPRLETNYSGLDYLPGLARLPG.TTTPEHDRSAYWGAARDRIPDAAHDLFPK.......PTDPVSLPPDSAVRGRGQH.LVGTNP.QNLAHIRSGQFWENCGQQEADAYERRLEPTLHEGLRYLMEHPHETEAMSVRYLRNEGDAAASG...............RPRKESCGAAFFGNLDSLERWAKTHPSHLAIYRGALSHY.KAFG...DLRRLRTWHEVSVLHEGDAQFEYINCAPATGH
Q0C7P1_ASPTN/35-346              TAYIGIQQHDDSAA....GQDAFRTAADVVREFVKS..MSCQDQSRVTETFRFLDGDDCKNAIIHVCYWEDARSYEEDLSRLRPMDIYTRVQ..RAPGIGIWCERFTTPISRLETNYSGIDYLPGLAQLSQ.GQPTEHTLTAYWGAARDRIPSSGHDAFPR.......DHPESATYPPQIPRGLGQR.LFGCNPYDNLVHIRSGQYWQRCDAAEAEAYETMLEPTLKTGLKYLWDTRDESGAIGLRFLRNEWGA...................EEAKETCAAGFFRNLDDLEQWAKQHPSHIAIFKGALKHA.RVFG...ENRKMRTWHEVSILKRGEAHFEYVNCQPHTGV
B8NPL1_ASPFN/36-350              TTYIGVQRHHG.......LDIGLTKCLAAIERWLA...TDQDNAPAAVERFRVIDGDDTPDSLVFACYWDTESKYENGIKGLNLTQLYQKLDKSIQPTVGLWCERFVSHVSRLETNYSGTDYLPGLARLPG.TKTVAHSYSAYWGAARDRIPDSAFELFEQ....DE..NPTATAIPDAMSTSLGKH.LTGTNF.HNVVHIRTGQFWNNCDEDEKRSYEDKLEPTLREGLSYLWQNPAETGSMGLRYLSNIPTSS..PEWS............GQSNESCVTGFFRSLADLETWAKKHPSHLAIYTGAIRHA.KTFG...DRRKFRTWHEVSVLRRGDAHFEYLNCLPGTGM
A1CY61_NEOFI/6-331               TAYVGVQRRGAQTD.EGLLTESVNAAVESIQRWIV...ENPSTAPASIEQFQVLDGDDVPNSTVWVCYWNEASKYEDSIRRLSLVNIHQKLNAPHRESVGLWCERFTSHLSRVETNYSGLDYLPGLARLPG.VSTVEHTLTAYWGAARDRIPASATDRFAQ....NEGLEKTQLAPETASPRKTNDYHVVGTNP.DNLVHIRSGQFWANCAEDETKAYEETLEPTLRAGLAYLWDNPQKSGAMGLRYLYNRPPSSGVLEKT............RETKESCVAGFFRNLADLEHWAKSHPSHLAIYTGAIKHA.KKFG...DQRKFRTWHEVSVLRHGEAHFEYVNCKDRTGV
A1CFW9_ASPCL/35-358              TAYIGVQDRESCANGQPIHNKAYQDAVEAIQTWIT...ADPSIAASSVEQFEVLDGDDTPGSTVWACYWDDAAKYEASLQRLNLVAPFEQLDSTNRQSIGLWCERFTTRLSRLETNYSGSDYLPGLARLPG.VSCLEHTLATYWGSARDRIPDSATELFER....EE.VDDHALKAR.SSPVSLKHY.VVGTNP.ENIVHIRSGQFWANCNDDETKAYKETLEPALRAGLKYLWEHPVQTGASGLRYLANRPGPAQSANTA............QDSRETCVAGFFRTLSDLENWAKSHPSHLAIYTGAVRHA.KKFG...EQSWFRAWHEIAILKRGEAQFEYVNCVIEANQ
C6WDR0_ACTMD/39-337              VARFGVQTDDS............AAGVKAIARVLEL..AAGESGPALV.ERVSDDDSE.....MAVCYWPDPEAHRAWWASGPVRDWWASL..PVDGPIGHWHETSVTPVEQFETLYS.AEFAAGPSRFAG...TGPTNLHDYDNSTLDRMPATAHRDLRQ.....ERAEEPTTDLPPGESPRGRRVRLAEPSP.SGLCWIRTAQEWSIAPDDQLASYRDGVEPAYRTAIAHLQDNPHDTGCLSARLVGNLDA....NGAR............A..AGAEAVVWWRGIGDLLRWAHDHKTHQDILNGFWEHVIAKFG...PGTRVRLWHEVHVLPEGALTAEYVNCHPGTGL
OXD_BACSX/28-329                 FAQIGIQSKSL............DHAAEHLGMMKKS..FDLRTGPKHV.DRALHQGADGYQDSIFLAYWDEPETFKSWVADPEVQKWWSGKKIDENSPIGYWSEVTTIPIDHFETLHSGENYDNGVSHFVP...IKHTEVHEYWGAMRDRMPVSASSDLES.......PLGLQLPEPIVRESFGKRLKVT..AP.DNICLIRTAQNWSKCGSGERETYIGLVEPTLIKANTFLRENASETGCISSKLVYEQTH....D.GE............I.VDKSCVIGYYLSMGHLERWTHDHPTHKAIYGTFYEML.KRHD...FKTELALWHEVSVLQSKDIELIYVNCHPSTGF
#=GC seq_cons                    hAhhGlQhpus.st.........stAhssltphlpt..hssssuPpth.-hsthsDssGhpshlhluYWp-sssacpWhpssshssaWsuhs...tpshGhapElhsssscRaETlaSsp-hh.Gluplhs.shos.hpcHuYWGuhRDRhPhopsDthts.........sspsth.sssstttGRlhls..sh.-NlshIRSGQDWussss-E+chYh-pl-PsLppGMcaLp-putcsGChosRahpshDs....c.ss............h.hccohsluaacsLssLE+Wu+oH.THlsIassFhchs.pshs....thcLRLaHEVuVLcsspthFEYlsCHssTGh
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