# STOCKHOLM 1.0
#=GF ID   Pyrid_oxidase_2
#=GF AC   PF13883.1
#=GF DE   Pyridoxamine 5'-phosphate oxidase
#=GF AU   Coggill P
#=GF SE   Jackhmmer:Q8IUH2
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF SQ   37
#=GS CREG2_HUMAN/118-284   AC Q8IUH2.1
#=GS B0R013_DANRE/109-275  AC B0R013.1
#=GS B3RZ50_TRIAD/28-193   AC B3RZ50.1
#=GS Q5KI24_CRYNJ/57-227   AC Q5KI24.1
#=GS B2W6Z7_PYRTR/40-215   AC B2W6Z7.1
#=GS B2AUP2_PODAN/34-234   AC B2AUP2.1
#=GS Q6CJ59_KLULA/39-202   AC Q6CJ59.1
#=GS C5DNB0_LACTC/26-195   AC C5DNB0.1
#=GS C4QX45_PICPG/25-204   AC C4QX45.1
#=GS C5M352_CANTT/28-215   AC C5M352.1
#=GS A5E0K5_LODEL/52-239   AC A5E0K5.1
#=GS A5DBJ2_PICGU/30-211   AC A5DBJ2.1
#=GS Q6BVV4_DEBHA/44-227   AC Q6BVV4.1
#=GS C4XX44_CLAL4/39-222   AC C4XX44.1
#=GS B8BXF8_THAPS/59-226   AC B8BXF8.1
#=GS A9D2A1_9RHIZ/10-162   AC A9D2A1.1
#=GS A6UBW0_SINMW/10-163   AC A6UBW0.1
#=GS B0WKF3_CULQU/49-218   AC B0WKF3.1
#=GS D3TMX0_GLOMM/44-213   AC D3TMX0.1
#=GS Q29A79_DROPS/39-208   AC Q29A79.2
#=GS B4PU76_DROYA/39-208   AC B4PU76.1
#=GS B4N9T3_DROWI/43-212   AC B4N9T3.1
#=GS B4K7L2_DROMO/35-204   AC B4K7L2.1
#=GS C3XSM7_BRAFL/12-180   AC C3XSM7.1
#=GS C1C112_9MAXI/61-228   AC C1C112.1
#=GS B5X4P6_SALSA/27-193   AC B5X4P6.1
#=GS A1L1S1_DANRE/25-192   AC A1L1S1.1
#=GS CREG1_CHICK/21-189    AC Q5ZJ73.1
#=GS CREG1_HUMAN/50-216    AC O75629.1
#=GS CREG1_HUMAN/50-216    DR PDB; 1XHN C; 14-180;
#=GS CREG1_HUMAN/50-216    DR PDB; 1XHN D; 14-180;
#=GS CREG1_HUMAN/50-216    DR PDB; 1XHN A; 14-180;
#=GS CREG1_HUMAN/50-216    DR PDB; 1XHN B; 14-180;
#=GS CREG1_MOUSE/50-216    AC O88668.1
#=GS A9SRZ7_PHYPA/16-179   AC A9SRZ7.1
#=GS A2XE58_ORYSI/40-204   AC A2XE58.1
#=GS Q8RY62_ARATH/37-200   AC Q8RY62.1
#=GS B9RUG5_RICCO/34-198   AC B9RUG5.1
#=GS C6SZN0_SOYBN/28-192   AC C6SZN0.1
#=GS D0P0T5_PHYIT/38-204   AC D0P0T5.1
#=GS A9V467_MONBE/30-197   AC A9V467.1
CREG2_HUMAN/118-284              PG.PRLRAATARSLAHASVWGCLATV..ST......HKK.....IQGLPFGNCLPVSDGPF...N...NSTGIPFFYMTAKDPVVADLMKN.PM..ASLMLPESE..............GEFCRKN.......IVDPEDP........R.CV...QLTLTGQMIAV....S......PEEVEF..A.KQAMFSRHPGMRKWPRQ......YEWFFMKMRIEHIWLQKWYGG...ASSI...SREEYFK
B0R013_DANRE/109-275             PP.HEETARVARYMAHQGDWGFLSTL..ST......LEQ.....IRGLPFGNIFSVSDGPA...D...NSTGVPYFYVTPMDNTVTDLRSF.PF..ASLTFSEAE..............GDFCRKQ.......VYDPEDP........R.CA...RLTLTGKMVEV....E......PEELDF..A.KEAMFSRHPVMKKWPPG......HQWFFMKMVLQQVWLQDWFGG...VSVV...PLEEYFK
B3RZ50_TRIAD/28-193              PP.FMQKVAMARYVVHQTNWSVISTI..SK........P.....FDGIPFGNVESFSDGPI...G...NSSGIPYFYLSPFDFALKDIVQH.PQ..VTATMTLSQ..............TGYCFSK.......HYDPEDP........R.CA...RVTVMGNLVKV....T.....KAKELQF..S.QHALFSRHPAMKSWPKG......HHFAIYKINITAVVALDFFGG...ADII...PAATYFA
Q5KI24_CRYNJ/57-227              ET.LEEAAVNTKKLIEDVTVGTMSSV..FP.....NGTD.....NGGRPFAMMEYHA...P...C...HPPPSLTFLLLPISLSTHNIMAS.SSHYASYSVAMPH..............KDEW............SPMS...........LS...RVAFIGNMTFL....PD...ISKEEKAE..L.EKCYLSYHPDAKYWLPGAS.NSPHSSVWAKLDADDIYYVGGFGD...THYIGHIPIDLYTK
B2W6Z7_PYRTR/40-215              PT.VHESAVQARRIMRLENIGTLSTVFPSTQATERRPSD.....VGGAPIGLMDYF..GDC...E...PETGNPTILAITIATSFKNVDAG.SN..ITLSMRWHP..............QDTK.............WRSP........ASLP...RFSLVGHLEDI....D......ADAVEKVGM.TACYVKKHPDAAWWLPGN...MIHESKWVRLVVEDIYWIGGFGD...RAYIGWIPKEEWFS
B2AUP2_PODAN/34-234              PT.ARESAILARRILTLTPLGTISTIFPST......TSSRNPPGIEGKPHALMEYIS..AC...D..PLAPSNPTLLSLNISSTFRNA.AN.AN..LSLAITWTPPPLPPPSRSFLSHLNPFSSEP.......PVQPQSY........S.AAALPRYSLMGYLEPI....PGADDPKSDVGKL..V.QTCYTNTHPDAKYWLPGN...RIHESHFVRLVVTEIYWVGGFGD...RAYIGWIDAKDWES
Q6CJ59_KLULA/39-202              LT.REYAAEVARGVVKYGDLVHVSTL..KD........G.....KTPVTFPEYYVSSDLCE...G..VNSTGNPILVLMNVSSTLRNYQDN.GK..LSITVEDRR..............PRHHAM.......................S.SP...RANLFGSLKKL....E......TT..KA..L.RDCYGKRHPDAIPWLPGEE.SLVHDGAFYEFEVEDLYYVGGYGF...QAYIGDIDGELYHE
C5DNB0_LACTC/26-195              LD.AHSAARFARRLALKERDAHANTI..DR.......ET.....GDPVSSVEYVVGSDACH...GVTTSQPGNILLLFVNASSTYQNWRDN.SR..FSLTLEKHH..............GRRP...........VPPL..........A.AP...RANFFGELKPV....E......RSD..A..L.DQCFLRKHPDAEHWLPGSKHHDVDDGQWYELDVSRVNFVGGFGKHGFAGEI...SGDEYHN
C4QX45_PICPG/25-204              HD.VKTAASVARTLVHRESLTQLNSI..YQ......SGD.....LEGVPV.SFVEYYT..D...C...FNDGNPLMLLVDISTSQKNIAEG.SP..YSLSIKVGD..............HQLTDK........KVNGKYPGETFKSTAG.SP...RVSITGELHDV....T......EQVSHNISV.TKCFVERHHDSLFWIPGKE..VAHSSKWWKFNVDSVYFVGGFGN...MAYIGKIPLQEYLS
C5M352_CANTT/28-215              PT.EEDGAAVARTLVNRESLANVNTI..KS......IKQ.....SDGTTLHLPVSAVEYYA...D..CDNDGDPYWLVIDIGGPNQNIIKG.SP..FSFTIRVGD..............HPKYDKDVSDEYPGSIDGSVA........G.SP...RVQLTGSLRSIYFDNP......FDPKKL..ALEKCFLQRHPDASAWLPSNY.LSPHKSHWAKLKVDGAYLIGGFGG...RGYIGEIDSELYHS
A5E0K5_LODEL/52-239              PS.KEEGASVARTLVHRESLFSVNTI..HT......FKS.....SHDESEVSVPVSSMEYF..AD..CDGDGDPYWLVIDVGSPNQDIIRG.SP..YSFSIRDGD..............HPSWDDVAEN.YPGKREGSNA........G.SP...RIQLFGKLEFVGFYNP......FDPRKL..ALEKCFLERHPDASLWLPGNV.VSPHKSHWTKLRVESVHIIGGFGD...VAYIGTIDAKSYHE
A5DBJ2_PICGU/30-211              PD.EDEAASIARTLVARESLANINTF..TS..............IPGRTGPIPVSLMEYYA...D..CDNDGDPYWLVVDIGSTNRNIARG.SS..FSWTIRVGD..............HP..RND.......DVDPNYPGAIPSSPAG.SP...RINLVGRLENV....TF...SNPRELIK..L.ERCFVARHPDAKYWLPYNP.ITPHNSHWTKFVVEEIYMVGGFGD...RAYIGTIDSKKYHQ
Q6BVV4_DEBHA/44-227              PS.IEDGARVARTLVFRESLVNVNTF..KT......VKS.....GDDETQLPVSSMEYYAD...C...DGNGDPYWLVVDIGSTFQNIEKG.SD..YSFTIRVGD..............HPFDED.........VDTSYPGSIKHSPAG.SP...RINLRGKLEDV....TF...ENSIEQLR..V.ETCFLKRHPDSETWLPRNK.ISPHKSHWTKLIVDEVYMVGGFGN...LAYIGTIEDDIYHK
C4XX44_CLAL4/39-222              PT.MKDGAIVARSVVQRESLANINTL..ER......VFK.....DNETLYVPVSSMEYYAD...C...DNDGTLYWLVVDIGSTYRNIDSG.SA..FSFTIRAGD..............HP..LND.......HVNPKYPGGIPSSPAG.SP...RVNLKGHLKNV....TF...ANPVDRIA..L.EKCFLSRHPDAKWWLPSNP.ASPHKTHWLKFEVEDIYIIGGFGD...RAYIGPVDADLYYD
B8BXF8_THAPS/59-226              PKIRLNVPEKARTVISVCTSGTLCTA..SH......MDD.....IQGAPFGSFVDYV.......L...DDKGNPVLLMNEMSMHTVNIQKSGPE..GLVTLFAQL..............GGPTSSS.......GVATQGQ........D.VS...RCSVTGTIEKI....ED....TAEDWDA..I.RMRYGIAHTYADQVMDS......PKFHFYRLSPKKIYYVGGFGV..SSEWV...PPEEYSE
A9D2A1_9RHIZ/10-162              DT.DEEARQLARRLVRGARFAAIGVL..EP..............ETGFPFTSRVLTG.......T...DTDGAPVILVSGLSVHTAALLDD.PR..ASLLFGEPG..............KGDPLA.........................HP...RITLRTLAVRV....P.....RDDERHA..ALRARFIARHPKAALYADF......PDFTFFRMVPESASLNGGFGK...AYVL...EASDFLI
A6UBW0_SINMW/10-163              ET.DDEARKLARVLLRSARSAALAVT..EP........G.....SGGFPFVSRVLVG.......I...DIDGTPVILVSRLSTHTQALTAD.RR..ASLLTGEPG..............KGDPLA.........................HP...RLTVQCAAEAV....PR....DGPLHQR..L.RERFLRRHPKSKLYVDF......PDFGFFRLKPLRASLNGGFGR...AYVL...TAEDLAI
B0WKF3_CULQU/49-218              PP.HTEYAKMARYLVHKAEWVSMGSL..ST......VDA.....IKGYPMVNVIAVADSAR...G..EKSTGTLYFYLTMLDYTAQDLSKD.NR..LTVLLSMDQ..............DLYCSKR.......GVDPMEP........T.CA...RIMISGRAVKL....ED....GNEEFNF..G.KDAMFSRHPAAQKWLST......HNFFLCKLEITQIAVLDWYGG...PHYV...TVDEYMK
D3TMX0_GLOMM/44-213              QP.DLNHAKIARTLVNHANWAAVGTI..ST......NRL.....VAGYPMVNVISIDDNDS...K..GVSTGKIHFMLTDLDFTGPDWRYN.NK..ATFLFSNDQ..............HLDCENH.......KEDPMEP........T.CA...RVIISGQVKQMG..RN......DQNYDD..A.LVAFVQRHPAAKNWIKA......HTFYLCELDIKNIFVLDYYGG...PHNV...TADDYYN
Q29A79_DROPS/39-208              EM.ELDHAKIARQLVHRANWAAVGSI..ST......NKI.....VENYPMVNIVSIDDSDA...N..GNSTGKIRFLLTDLDFTGPDWEKN.NK..VTLMFTEEQ..............TLNCKNH.......GKDPMEP........T.CA...RSMISGQVQRF....D......KSDRSYKPA.LDAYIKRHPSANNWIKA......HNFYLCELIIRNIFVLDFYGG...PHQV...TASDYYA
B4PU76_DROYA/39-208              QQ.ELNHAKIARDLVHRANWAAVGSL..ST......NER.....VKGYPMVNIISIDDSDA...N..NRSTGRIRFLLTDLDFTGPDWQAD.NK..VTLMFSDEQ..............TLRCKDG.......GKDPMEP........T.CA...RSMISGQVKKM....D......PSDRSYQPS.LDAYVKRHPAAINWVKA......HNFYLCELEISNIFVLDFYGG...PHKV...SASDYYA
B4N9T3_DROWI/43-212              EL.ELNHAKIARQLVHQANWASVGSI..ST......NKI.....VENYPMVNIVAIDDNDV...H..GNSTGKIRFLLTDLDFTGPDWQKN.NK..VTFTFTDEQ..............TLNCQKA.......GKDPMEP........T.CA...RTMLSGQVKKM....V......EDDASYKPA.LDAFLKRHPAGTNWLKF......HTFYLCELVIKNIFVLDFYGG...PHEV...SASDYYA
B4K7L2_DROMO/35-204              QL.ILNHAKIARQLVHRANWASVGSI..ST......NKI.....VKDYPMVNIISVDDNNL...E..GKSSGVIRFLLTDLDFTGPDWQNN.NK..VTFLFTDEQ..............TLNCKNA.......NKDPMEP........T.CA...RVIISGQVKKL....P......KDEPSYTPA.LNTFIARHPAAVNWIKE......HNFYLCELDIQNIFVLDFYGG...PHQV...NASDYYA
C3XSM7_BRAFL/12-180              PP.HGDYAATARYVVHNNDWGSLASI..ST......HQP.....MKGKPFTNVFSVSDGPV...G...NGTGVPYLFLSPLDVTDQDLQVN.NN..ATLSMSEVM..............SGYCASQ.......KWDAEDP........R.CA...KIILSGKVVNV....P......EAEIDF..A.KNALFTRHPIMEDWFKME....SHKFYFAKMQIEAVFVLDFFGG...GNIV...TPEDYFN
C1C112_9MAXI/61-228              PP.HEKVAKMARYVVHLSDWIAISTI..ST......RSP.....TKGRAFANVLSMSDGPN...K...NSSGVPYFYLTPMEMSVRDLKVD.NN..ASITASLAE..............TNYCARM.......EYDPMDP........L.CA...HVILNGKIVEV....S.....SAEEKKF..A.KRSLFSRHPEMADWPVG......HNWFFAKMNIENILVLDFFGG...AKTV...PVEAYYK
B5X4P6_SALSA/27-193              PP.HEEVARMARFVANQCNWASMATI..ST......HEP.....VQGQPFSNVFSTSDGPV...G...SGTGVPYMYLTTMEISVQDLKVN.PQ..ASLSMSLAQ..............TDFCKNQ.......GYDPQDP........L.CA...HIIFSGSVLEI....N......GTEATF..A.KKALFSRHPEMVDWPTD......HNWFFAKMNITKVWVLDYFGG...VKTV...TPEDYFK
A1L1S1_DANRE/25-192              PP.HEQVARMARFVVSKSDWASVATI..SS......REP.....VRGQPFSNSFSISDGPP...G...ASSGTPYLYLTHLDISVQDLQVN.PQ..VSLSMSLAQ..............SSYCRNH.......GYDPQSP........L.CA...HVILSGSLLQL....N.....DSEEVCV..A.KRALFSRHPQMQDWPSD......HGWFFSKINITQVWVLDYFGG...VKTV...TPDEYYR
CREG1_CHICK/21-189               PP.PEEAARMARFVLHNCDWGALATL..SA......QEG.....LRGRPFANIFSISDGAP...GP.GGGSGVPYLYLTDMEISVQDLEVN.SN..ASLTVSLAQ..............TPYCKKH.......RYDPQNP........L.CA...HIIFCGSIVKV....N......DSEAAL..A.KKALFTRHPEMESWPKD......HNWFYAKFNITNIWVLDYFGG...LKIV...TPEEYYN
CREG1_HUMAN/50-216               PP.REDAARVARFVTHVSDWGALATI..ST......LEA.....VRGRPFADVLSLSDGPP...G...AGSGVPYFYLSPLQLSVSNLQEN.PY..ATLTMTLAQ..............TNFCKKH.......GFDPQSP........L.CV...HIMLSGTVTKV....N......ETEMDI..A.KHSLFIRHPEMKTWPSS......HNWFFAKLNITNIWVLDYFGG...PKIV...TPEEYYN
#=GR CREG1_HUMAN/50-216    SS    --.TT-HHHHHHHHHHH-SEEEEEEE..--......SGG.....GTTSEEEEEEE-BSSST...T...---S--EEEE-TTSHHHHHHHH-.-E..EEEEEEGGG..............SSHHHHH.......T--TTST........T.S-...EEEEEEEEEE-....-......TTTHHH..H.HHHHHHH-GGGGGS-GG......G--EEEEEEEEEEEEE-SSSS...-EEE...-HHHHHH
CREG1_MOUSE/50-216               PP.REDGPRVARFVTHVSDWGSLATI..ST......IKE.....VRGWPFADIISISDGPP...G...EGTGEPYMYLSPLQQAVSDLQEN.PE..ATLTMSLAQ..............TVYCRNH.......GFDPQSP........L.CV...HIMMSGTVTKV....N......KTEEDY..A.RDSLFVRHPEMKHWPSS......HNWFFAKLKISRIWVLDYFGG...PKVV...TPEEYFN
A9SRZ7_PHYPA/16-179              PD.PSDAPATARWLVAQSAWGVLSTI..SI........H.....LEGAPWGNVAAFSDGPV...G...SSGGTPFFYLSRMDPTPNDITLD.SR..CSLTLSEAS..............LGTCGS.........VDPENP........T.CA...RLTLSGKMMEI....T.....DQQELDF..A.ALALFSKHPEMPDWPKW......HKWIFYKLDILNIYLLDNYGG...AKPV...TVSEYYR
A2XE58_ORYSI/40-204              PA.PTEAAATARWLAAQNTWGVLSTI..SS........D.....LSGAPFGNVVSYSDGVP...G...ESHGIPYFYLTTLDPTARDALED.ER..TSFTLSEFP..............LGTCGK.........IDPENP........T.CA...KLTLTGKLKLI....DP....QSSEADL..A.KEALFTKHPEMEGWPKN......HHFQIFKLEIKNIFLIDWFGG...PKPI...SPTEYLE
Q8RY62_ARATH/37-200              PD.RHDYAASARWLVSQNSWGVLSTL..SV........D.....HKGAPFGNVVSFSDGLP...E...KGNGIPYFYLTTLDPTARNALKD.QR..ASLAISESP..............LGTCTR..........DPMNP........T.CS...KLTLTGKLLIL....EG....GSEEAEV..A.KKALFTKHPEMMDWPKD......HDFRFFKLEIIDIFLINWYGG...AKPI...TVDEYLH
B9RUG5_RICCO/34-198              PD.RDNAAATARWLVSQNSWGVLNTI..SM........D.....LGGAPFGNVVSFSDGLP...N...EGSGIPYFYLTTLDPTARNALKD.QR..SSLTISEYP..............IGTCGK.........TDPENP........T.CA...KITLTGKLKLL....EE....NTKEAEF..A.RTALFTRHQEMPGWPKD......HNFQFFKLDIEDIFLINWFGG...PKPL...TLDEYFH
C6SZN0_SOYBN/28-192              PN.PDDAPASARWLVSLNFWGVLNTI..SS........D.....LGGAPFGNVVSYSDGLP...N...ESTGISYFYLTTLDPTARNALQD.DK..ASFTVSEYP..............LGTCGR.........RDPMNP........T.CS...KISLTGKLKLV....DE....KSKEAEF..A.RNALFSKHPEMKDWPED......HNFQVFKLEIENIFLINWFGG...PKPL...TVEQYLH
D0P0T5_PHYIT/38-204              PF.AKLHAKHARMLVHENVWGIMATT..SV........T.....FGSAAFANVVSYSDGVGVAKE...DATGTLFFYLSVDDFTAMDLKAN.PS..ATIALSKAQ..............GG.AKAC.......LMDAEDP........T.CW...RLSMTGRVVPV....N......ENQRNY..A.ERAVFSKHPQMKHWPKH......HDFSFYVMEIEHIVFLDFYGP...AQHI...PVSDYYK
A9V467_MONBE/30-197              PD.YQDKVGVARWLAHQAVEGVLATT..ST........A.....FPGYAFGNTQSFADGTI...K...NSTGHLFFYVSNLDASIQDILVD.PR..CTFTLSEVE..............TNFCKQN.......HYDAEDP........R.CA...RLTFVGTYRNV....T......SAEEPH..A.QAALFDRHPEMKSWNSQG...SFHDFHFTTLEIEHIWLVDMFGG...AADV...DVKQYYA
#=GC SS_cons                     --.TT-HHHHHHHHHHH-SEEEEEEE..--......SGG.....GTTSEEEEEEE-BSSST...T...---S--EEEE-TTSHHHHHHHH-.-E..EEEEEEGGG..............SSHHHHH.......T--TTST........T.S-...EEEEEEEEEE-....-......TTTHHH..H.HHHHHHH-GGGGGS-GG......G--EEEEEEEEEEEEE-SSSS...-EEE...-HHHHHH
#=GC seq_cons                    Ps.tc-sAphARhLVppssausluTl..So.......ps.....hpGhPasslhShuDsss...s...susGsPaahLosls.ospslpps.sp..sSloho.sp..............pshspp.........hDPpsP........s.Cs...RlplsGplppl....s......sp-hph..A.ccshhsRHPchppW.ps......HsaaahKLplpsIallshFGG...sphl...ss--Yap
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