# STOCKHOLM 1.0
#=GF ID   NST1
#=GF AC   PF13945.1
#=GF DE   Salt tolerance down-regulator
#=GF AU   Wood V, Coggill P
#=GF SE   Jackhmmer:Q09863
#=GF GA   20.00 20.00;
#=GF TC   20.60 21.70;
#=GF NC   19.70 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11816027
#=GF RT   Involvement of Nst1p/YNL091w and Msl1p, a U2B'' splicing factor,
#=GF RT   in Saccharomyces cerevisiae salt tolerance.
#=GF RA   Goossens A, Forment J, Serrano R;
#=GF RL   Yeast. 2002;19:193-202.
#=GF DR   INTERPRO; IPR025279;
#=GF CC   NST1 is a family of proteins that seem to be involved, directly
#=GF CC   or indirectly, in the salt sensitivity of some cellular
#=GF CC   functions in yeast. It does this without affecting sodium
#=GF CC   accumulation. It negatively affects salt-tolerance through an
#=GF CC   interaction with the splicing factor Msl1p. This interaction
#=GF CC   stresses the importance of efficient RNA processing under salt
#=GF CC   stress conditions [1].
#=GF SQ   7
#=GS NST1_COCIM/120-303    AC Q1E1H4.1
#=GS C1G113_PARBD/166-347  AC C1G113.1
#=GS A6QRV2_AJECN/167-345  AC A6QRV2.1
#=GS NST1_EMENI/91-273     AC Q5B3C8.1
#=GS D3AYA3_POLPA/105-290  AC D3AYA3.1
#=GS NST1_SCHPO/153-345    AC Q09863.1
#=GS B6JVK9_SCHJY/147-313  AC B6JVK9.1
NST1_COCIM/120-303               TDDETHYSTQGQRGL.QHDKN...GVLHQSQEPSKRKGKKKKNRK.SRSQSHQAEGSST...SMSTPSASL.ARP.VTLP.PLSSS....AYRSAHKVTKDR.IWNTSTHEERERIKEFWLQLGEEERRSLVKVEKEAVLRKMKEQQKHSCSCTVCGRKRTAIEEELEVLYDAYYEELEQYANHKQGSFENGAPIGAPPR
C1G113_PARBD/166-347             TDDEGHIYAQPHSQSHSDKFN...MVQHSDLSMNKSKKK..KGKR.HRSTSHLADGSST...SLPTPSASA.ARPAQPPPLSN.....AALRSAHK.ISKDR.IWNTSTQEERENIKEFWLQLGEEERRSLVKVEKEAVLRKMKEQQKHSCSCTVCGRKRTAIEEELEVLYDAYYEELEQYANHSQNSFENGGPIV.PPR
A6QRV2_AJECN/167-345             TDDDGHLYAQRHSQTHPDRRS...MDQHSEASGSKSKKKKSKKHR.STGSSTSVSTQRT.....STTRPA..APPPPPLS.......NAALRSAHK.ISKDR.IWNTSTQEERENIKEFWLQLGEEERRSLVKVEKEAVLRKMKEQQKHSCSCTVCGRKRTAIEEELEVLYDAYYEELEQYANHSQSSFENGGPIV.PPR
NST1_EMENI/91-273                YDDKSEKVLNGHGHN.TQELP...HPSEHDPQGTTSRKSKKKRGK.KGRNGSQASS..T...PMSTPSISLSNAPRPPLSSHFGSQ......SSSKLLKERS.IWNTSTQEERENIKTFWLELGEEERRQLVKVEKDAVLKKMKEQQKHSCSCTVCGRKRTAIEEELEVLYDAYYDELEQYANNTQGSFERGPAILPPPG
D3AYA3_POLPA/105-290             QQQQSNENSIEQQQQQQQQFDVDHSNIVNNSNIEKKKKKKKKRSS.ATSPSINNNVDSNN.NNQQ.........QQQQIKQSPPFAAQQQQQQSVK.SKEKK.MNTGSQEVDKQLLREFWISLTEDERRELVRLEKESLLKKMKDQQKHTCSCSVCGRRRVVIEEELEMLYDSYYEKLKYYEKM.NDKVSYLIDLKDSQQ
NST1_SCHPO/153-345               LEDATSSNMSPNSVQNNMNLN...TVALGSSTSSKRKKKKKKKSK.ANSASLNVDDQRDFEQVYSTDVAIT.YRNGQALSYYNGSVRQASMNNNVNNNKSKD.IWSSSNTEEREQIREFWLSLSESERRSLVKVEKEAVLQKMKEQQKYSCSCSVCGRKRLAIEEELEVLYDAYYEELEQYANI.QRNLANTESVNASDE
B6JVK9_SCHJY/147-313             LDDG......PAGSQ....LT...T......SSTKKKKKKKKKSKGAQKEGYGASD...SYEVPSHRQPI...HN..QLAYPSRNT.....SNALINWKPKDKIWSTSSTEERERIREFWLSLTEDERRSLVKVEKEAVLQKMKEQQRYSCSCSVCGRKRMAIEDELEVLYDAYYEELEQYANI.QRNKAAAAAAGVAMG
#=GC seq_cons                    hDDpsp..hpspupp.ppphs...ts.hps.ssoKpKKKKKK+p+.upusShpssspps...s.STsps....ts..sLs...........psuh+.hpccc.IWsTSopEEREpI+EFWLpLuE-ERRSLVKVEKEAVL+KMKEQQKHSCSCoVCGRKRsAIEEELEVLYDAYYEELEQYANh.Qsshpsusslssssp
//