# STOCKHOLM 1.0
#=GF ID   DUF4225
#=GF AC   PF13988.1
#=GF DE   Protein of unknown function (DUF4225)
#=GF AU   Bateman A
#=GF SE   Jackhmmer:B2PH01
#=GF GA   24.10 24.10;
#=GF TC   24.40 24.60;
#=GF NC   23.60 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR025320;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   family of proteins is found in bacteria and eukaryotes. Proteins
#=GF CC   in this family are typically between 182 and 282 amino acids in
#=GF CC   length.
#=GF SQ   24
#=GS Q1IC01_PSEE4/72-217   AC Q1IC01.1
#=GS Q1IAW7_PSEE4/55-200   AC Q1IAW7.1
#=GS D1P2G8_9ENTR/185-334  AC D1P2G8.1
#=GS D4C109_PRORE/97-304   AC D4C109.1
#=GS Q7N2U7_PHOLL/67-252   AC Q7N2U7.1
#=GS B2PH01_ECO57/69-253   AC B2PH01.1
#=GS D3V499_XENBS/4-172    AC D3V499.1
#=GS A7FCF9_YERP3/74-240   AC A7FCF9.1
#=GS C9Y5S8_CROTZ/75-242   AC C9Y5S8.1
#=GS E6WNV6_PANSA/79-247   AC E6WNV6.1
#=GS D4E2Z5_SEROD/75-244   AC D4E2Z5.1
#=GS D4GJC4_PANAM/74-244   AC D4GJC4.1
#=GS C4S408_YERBE/75-244   AC C4S408.1
#=GS Q6D8A6_ERWCT/90-256   AC Q6D8A6.1
#=GS C4SD80_YERMO/75-241   AC C4SD80.1
#=GS B5EWC2_VIBFM/67-238   AC B5EWC2.1
#=GS B7VPJ1_VIBSL/67-238   AC B7VPJ1.1
#=GS Q1IBL6_PSEE4/23-168   AC Q1IBL6.1
#=GS C7BU46_PHOAA/87-249   AC C7BU46.1
#=GS A7FGE6_YERP3/89-264   AC A7FGE6.1
#=GS D0KDQ0_PECWW/84-263   AC D0KDQ0.1
#=GS Q7NAC8_PHOLL/61-230   AC Q7NAC8.1
#=GS D0FP72_ERWPE/64-230   AC D0FP72.1
#=GS Q7N2C9_PHOLL/66-232   AC Q7N2C9.1
Q1IC01_PSEE4/72-217              LIELRNERDRLKAQSERITLQ.................................AIGVVGGTGQIITGAGIC...YGS......LGLLCATLGSPMIAHGGNNIYENARGLYE..GRD..........DVEGPVKKGYREISK.SLGYTEREGTLAYLATDATLSLRALLRPV................................LKADAWRLYK.YYSVDKEMAVKQ.....MSGSAV
Q1IAW7_PSEE4/55-200              LERILAEKKSLYSQASRIFTQ.................................LGGMAGGASQLATGLGNC...IGS......FGSTCAIHGAPLIMHGGNNLYENARGLYE..GRT..........DVVGPVRELYQDAAK.SLGYSERDGNLAYYTADLFLSGRAMWRKV................................PRRDAWRLYR.YMDADKERKIKQ.....LGKGGL
D1P2G8_9ENTR/185-334             SAELKQEEKSLREQAFDLISN.................................GLSILRGIAMTGVGIGLC............STGLGCLIGAPLIAHGVNGIYEGGVGIYQ..GDS..........NIQGPLREGYKATAK.LLGFNESVGNLAYDLIDLGISISGKLKLI........................PKLNEYGNP..NKNLFFKEYVRKDLEYAYKQ.....LSNRLL
D4C109_PRORE/97-304              TEEIKLEYESEKLAYSQLRKASKELYNATRSY...........FGEGWLFYGDKSLDILGGAIQTAVGIFSYRIGKTI......GSHGMKTSGAISMAYGGGRVYQGISDITYELTDG.......EINFRQDPVKFLIEQGTI.ALGGDSITAKKIYYDVDFVNNLYIGFGAFKIIDPKKRTEIRQLPTKTSKGLRKLGFFERYFPDNVGFRIER.WTSENYKRKLAI.....GNKPML
Q7N2U7_PHOLL/67-252              IYAVKDEYEITEKEYQALRRKDYTKYIVTDIF...........EDQGVVKYAKIGGGVVAGIAQTAAGIAVINSGRIV......RSKRVQLMGAVLVAHGGSNFYEAISPIL...YEN..........QKIGLVRKGYRYASH.ALGYGDDVADVAYSSVDLVASLYGTYGVL..............KLKPVKSKNNISGGYSVKP..GTGKLFR.YINSDLARKWQL.....TPKPML
B2PH01_ECO57/69-253              INELKMESETARKEYQLFRQGNYDKYITTDIF...........EEHGLIKYVNLSFDIVASVGQVVGGVGALKFGKVV......HSNRIKGIGVTLVAHGANNFYESLSPLF...FNE..........YDSGPIRELYRVIAK.KMGGDINSADYAYSIVDFSITAYGGYSGM..............KIVP.KYNRLIRPSLGNRP..GTGRLFH.YTSVDFKNKFSL.....KPTPLK
D3V499_XENBS/4-172               IQDLKKEKLYLSQQENIIRNNILEKYAVIEIK...........KELDFFTYVLKGFGIVAGGAQIITGAAMVT..ATS......QTVVGYVAGSALIVNGMSNIEENLNSLLK..KDP..........DYKGYLRRGYEHAFL.FMGSDKKTANLVYGGVDIALSGYGAFRNV........................LK......P..DSWRLFN.YVKDDYVTSYKL.....MSGYAL
A7FCF9_YERP3/74-240              IQNLKSEYDALHYQDRLIRNKNASFYSSIKIIK..........ENERIIGYVITGFNIILGGVQLFTGGLM....MST......MPVLGQMFGVIMVVDGVNTVDKNVSKLL...GDN..........ETEGLVADGFISTAG.FLGVERNSALASYTAISLGANVYSIYGLA........................FR......S..NSWKLFY.TMRSDFVRKVDN.....MSMPKL
C9Y5S8_CROTZ/75-242              IKTLRAENDSLLEQSRALKSGYAKLYAEVKVVK..........EENKIIGYIISGVDVVIGGIAIFGGITM....MAT......MTPMGVIAGAIIIVNGVNTITKAAARTLL..DDK..........KTEGIFADGSMEVAE.FLGFSRQQGLGAYKAVTLVSDVYGMYGLR........................LR......P..EVQRLWY.WTRPDFFRKVSK.....TSRPMM
E6WNV6_PANSA/79-247              IKKLREETENLREQDRLLRMQTAKLIAKVEFIR..........DNNKIVGYVISAVHIVLSGVAMFGGMIM....ISS......MTPIGMLAGATLFIDGVNGISKEVS.HLRYGKES..........HSEGIFADGAMEAAQ.FMGFSPNTGLAFYNAATLSASVYSVFGLA........................RK......P..GAWRLFR.WLPRDYYRKVDT.....MSRPKL
D4E2Z5_SEROD/75-244              IKNLRTETDNLLEQERLLKTKSAQLYAKIEFVR..........ENNKIVGYVISAVNVVLSGVVLFGGFMM....LST......MGPIGMLAGAVLIADGMNGLTKEVLNFNQPAGHK..........PSQGIIADSAMHTAQ.FMGFNPNTGLAFYHGVTLGASVYSIVGLA........................RK......T..GTWRLFR.WLPHDYYRKVST.....MSTPKL
D4GJC4_PANAM/74-244              IQNLKQETQNLKIQDRMLRTGEAVVSSSVQFYH..........DHEKVIGYVIDGIGVVLSGMQIVAGVGLIVGSVTT......GNVIGVVAGSALVMNGVGSGIESIGKLS...GVP..........HPSNPVRDKYEDAAD.FLGFDKRLGLLTYQVVDLTTSYYGLFKLT........................LK......P..EAWRLYK.YLPTDHYRKVQL.....LSKPAL
C4S408_YERBE/75-244              IDNLKMECYHLSRQDSMLSLKQARVYISAKIE...........EHDKVVGYVIDGIAVILGGMQLVAGLGIIAGSIAT......GNVVGTIVGVHLILNGASSSIAAIERLK...GNE..........NATDFMQDAYMGTAE.FFGFERKTGMLAYYTADLTTSFYGVIKLS........................LK......P..DAWRLYK.YIPSDYYRKINS.....MSKPAL
Q6D8A6_ERWCT/90-256              INNIKEECANIEKQGTMLSLEKAKVFITISME...........KRDKEFGYTINAIGVIVGGAQFVSGVGIA...YAA......TGYLGRFIGAHIALNGASSLSESIFHLI...GRE..........DSVGFMKSGYVRTAE.FLGFDKRSGLLAYHSVDLVTSFYGIVKLT........................LK......P..DAWRLFR.YIPSDYYRKINT.....MSRASL
C4SD80_YERMO/75-241              INNIQEECANIERQGTMLSLDRAKVYMTINME...........KYNNEIGYTINAIGVVGGGLQALSGAGLI...VKS......GFVIGKLAGVHLTLSGASTVAEKVYHLL...GQD..........NYVGFMEKGYRITAK.FMGFEPKAGSMAYHAVDMASSLYGVAALS........................LK......P..DIWRLFK.YIPSDYYRNYTK.....MSQGAL
B5EWC2_VIBFM/67-238              VNYVRQERQSLIDQSIEIGKY.................................TIGLVAGVGQVTTGYGLC...MTSSIFSFVGASWCVSTGAPMMLHGGNNIYENSYNITGNITQNWKKKYTGDYGSNNSFLRNGYRAGAK.QLGYSDTEGDLAYGLADIATSFYGLSNSL........................KTSTVSSIPNAKQFKLYS.YYATDYQKGWRT.....MTRGAL
B7VPJ1_VIBSL/67-238              VRLVKQERQSLIDQALELGKY.................................GIGLVAGVGQLSAGYGLC...VTSSIFSIAGASWCSGVGAPMITHGGNNIYENSYNMTGNIVQNWKGEYTGDYGNSNSTLRKGYQKIAA.SVGLSERDGNMAYATVDIATSVYGLKSTL........................KTVPHANVPNAQQFKLFY.YSSRDFSKGWRT.....MSKGAL
Q1IBL6_PSEE4/23-168              LNLIKKEHVELTQQALQYSRL.................................VAGLAAGVLQVAGGVAVC...KLS......AGIACATGGIALVQHGINGIYENGRNIIQ..RRT..........DTVGPLRSGYQEMAK.ALGGKASHGNVAYGVMEIALSVFGLTTLV........................VS......R..SAWRLYR.YVRADMVPAYKK.....MGTILV
C7BU46_PHOAA/87-249              IDLLEEEIKSLKEQDRMISQKNVRQAIVVQKEVIDSPRNS...KRREFDKLIIAGVGFISGGLQIVGGLTV.............TRLSRSGYGGLLLAHGYNNVIENGYYIL...YRE..........DYAGPVRFVYRQVAKETFNMNERDADALYASVDIGISLTGMLTYQ........................LL......P..DHQRLYR.YTC..............YLSSCL
A7FGE6_YERP3/89-264              IKLLDKELSDLRNQDEEMTRERVKQAVIIKASVKKNNDV....KRREIVSLTIAGVGFVTAGLQIVAGVGMV............GSVAGTIPGALLIAHGTNNIIENGYYIL...YRE..........SYTGPLKFLYEGVGA.QFGLSKSDADVMYTAVDIALSINGIMSYK........................LT......E..DAARLYR.YVNADLLWGLKSMGIKNMTTAEI
D0KDQ0_PECWW/84-263              IYSLKQEIATLKRQDQMLAMKQMKQVIIAKPAVTEENRNSGTNDTTQHINLVIAGLGFVSGGLQLVAGAGIA............GTGAGIIPGTLLMAHGFNNVIENGYYLL...YRE..........SYTGPVRFVYRQIGS.QLGLSNKNSDVIYTFVDIGLSINGLFGYR........................LT......E..DAQRLYR.FINADLLWGMKQMGMKLMSKSEF
Q7NAC8_PHOLL/61-230              IEIIQFEIDHLKEQAFCLTANRVKQYAIIEREK..........EKSSYTNLILKQIGFVGGGTQILAGYTVC...KAS......LGLACASFGAPLMAHGYNNVVENGYYLL...YRE..........NINGGVREGYRYVAN.KIGLSDKDADITYATVDLVLSGYGIFRKV........................LK......PREKSWSLFR.NINSDFIRGWRE.....MGVVSL
D0FP72_ERWPE/64-230              YEIIKKETERLRLQEFDIISGKVKQYLAIEKS...........VRDKKANLFLKQIGFVSGGSQVFAGFGVC...AAS......LGVACATYGTPLIVHGMNNTYESGYYLL...YRT..........EKQGYTRQAYREVAQ.KLGYSDNKANLAYASIDIALSGYGMARNV................................PKQDSWRLFN.HINSDFIRGWQE.....MGKVPM
Q7N2C9_PHOLL/66-232              IAILQDEIDNLKRQEFDLLMNDSQIYMIVQKE...........EEDEKTNLTLKRIGFVSGGSQIFAGLGVC...VAS......LGAACAGFGVPLLIQGGNNVYENGYYLL...LRK..........EVSGPVRDVYRDAAK.TLGYSETDGDRVYGYVDLALSGYGMARSV........................VR......P..GTFRLFR.YIKTDYIRGWQV.....MGRIPL
#=GC seq_cons                    Ippl+pEppsLccQsphlpppphp.hh.hph............cppphhthhltulGlVuGGsQlhuGhulh...hso......tsshsthhGusLlscGsNslhEsshtlh...tcp..........shpG.l+cuYcpsAp.hlGhscpsushsYssVDluhShYGhhphh........................lp......P..ssaRLa+.YlssDah+thpp.....MopstL
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