# STOCKHOLM 1.0
#=GF ID   DUF4375
#=GF AC   PF14300.1
#=GF DE   Domain of unknown function (DUF4375)
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:A7VAK3
#=GF GA   25.00 25.00;
#=GF TC   25.20 25.30;
#=GF NC   24.90 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR025402;
#=GF CC   This family of proteins is found in bacteria. Proteins in this
#=GF CC   family are typically between 156 and 204 amino acids in length.
#=GF CC   There is a single completely conserved residue G that may be
#=GF CC   functionally important.
#=GF SQ   41
#=GS B4UC92_ANASK/69-190   AC B4UC92.1
#=GS D5SN65_PLAL2/354-475  AC D5SN65.1
#=GS D2R6H4_PIRSD/372-493  AC D2R6H4.1
#=GS A1AMJ3_PELPD/102-225  AC A1AMJ3.1
#=GS Q67MQ8_SYMTH/193-311  AC Q67MQ8.1
#=GS C3WI31_9FUSO/44-164   AC C3WI31.1
#=GS D2MNA7_9FIRM/215-337  AC D2MNA7.1
#=GS B0UU67_HAES2/219-340  AC B0UU67.1
#=GS C0W1X9_9ACTO/213-335  AC C0W1X9.1
#=GS C4G3D4_ABIDE/376-496  AC C4G3D4.1
#=GS C4FQ05_9FIRM/211-330  AC C4FQ05.1
#=GS D1YMW7_9FIRM/211-330  AC D1YMW7.1
#=GS D4DR71_NEIEG/94-215   AC D4DR71.1
#=GS A5FIX3_FLAJ1/87-202   AC A5FIX3.1
#=GS A1ZW05_9BACT/57-176   AC A1ZW05.1
#=GS D4DQ08_NEIEG/33-156   AC D4DQ08.1
#=GS C6S5G2_NEIML/36-159   AC C6S5G2.1
#=GS C0ELJ3_NEIFL/38-161   AC C0ELJ3.1
#=GS D3A070_NEIMU/36-159   AC D3A070.1
#=GS C0DXG8_EIKCO/27-150   AC C0DXG8.1
#=GS C4GFB9_9NEIS/27-146   AC C4GFB9.1
#=GS C2FX52_9SPHI/41-164   AC C2FX52.1
#=GS D2F007_9BACE/98-220   AC D2F007.1
#=GS C6IR04_9BACE/48-170   AC C6IR04.1
#=GS C6ZAX8_9BACE/43-165   AC C6ZAX8.2
#=GS B5CYF6_9BACE/43-165   AC B5CYF6.1
#=GS C9LGK3_9BACT/61-183   AC C9LGK3.1
#=GS D3IGI0_9BACT/42-164   AC D3IGI0.1
#=GS D3IDY0_9BACT/41-163   AC D3IDY0.1
#=GS D1W2H6_9BACT/41-163   AC D1W2H6.1
#=GS D1VZH6_9BACT/41-163   AC D1VZH6.1
#=GS D1QMD4_9BACT/41-163   AC D1QMD4.1
#=GS D1PVD4_9BACT/41-163   AC D1PVD4.1
#=GS D1PGJ9_9BACT/41-163   AC D1PGJ9.1
#=GS D3HVY7_9BACT/41-163   AC D3HVY7.1
#=GS C9MQK5_9BACT/41-163   AC C9MQK5.1
#=GS D1XYX1_9BACT/41-163   AC D1XYX1.1
#=GS Q72QV3_LEPIC/21-142   AC Q72QV3.1
#=GS A6EN84_9BACT/44-165   AC A6EN84.1
#=GS A4C004_9FLAO/32-152   AC A4C004.1
#=GS A3J5H0_9FLAO/32-154   AC A3J5H0.1
B4UC92_ANASK/69-190              V.GFDELSPSEAALLDVWALEAEVNNGGFDQYFLNASGDRA..RGALAGLELIGAEKAAAITRRALAVFGPR.GPAPSQEAR..QKQMDSWN.PE.....V..EA....TLEALDQEFY..AYPD..PLAELMERHCRAHREAF
D5SN65_PLAL2/354-475             L.GFDDLSSPLKLYLAVRIYDSEVNNGGHTQFFSNSSGGHWM..EALKGLKEMGAHERAKVLEEAIKLFGAS.GPSRNDENR..HKELAKLV.SR.....H..RK....LFESLDDRYY..SCTE..DVNVLLAKFAVQNKQHF
D2R6H4_PIRSD/372-493             A.SEPVLNQQQKLYQLVWDTDSAISDSGIFWYFQSSSGDRW..REALASFETLGLKEHHAILSEAVALFGSD.GPAADLETR..TRQMKARFSEE.....G..TE.....FEALDARYF..ETEE..SLKIHTTNYVLENVDAF
A1AMJ3_PELPD/102-225             E.HIERLSKECRLVYLLWCFDGEIHNGGFDQLFTNSLGNHCL..EILQDLDVIGAKKSYDLLRIALSWFPNS.SPSTNRRERWTQYELFSEQ.QK.....Y.QTD.....MDRLDKEFY..KDED..KLANLICDYVMHHGSAF
Q67MQ8_SYMTH/193-311             A.SLAPFTRGQRLVYALQMYRLEVDNGGHGQFYGNSGG..IVWRDALEGFELLGLRELADNLRASAALLGGD.P.PLDRGER..EALLSELR.PD.....F..A........EITEQFW..KLEAQHDVDGAILAYARAHPEEF
C3WI31_9FUSO/44-164              E.SLKPYTTEQRYLLAMHWLGAEVANGGFQQFLSNSTG..IVWEDAYKGYQAIGSEKLAYLIEELIKIYGRD.I.PFDREER..GNILESFNQEK.....L..EE.....IDAITDLYY..EIEE..PEWRKVTLWVKANSEKF
D2MNA7_9FIRM/215-337             E.SAKSFTLEQRYLLAIIWYFIEVNNGGHHQFFFNSTG..IVWEDTLNGFRLFGMNHFANNFEKVIDYFGGK.I.PLDREER..LKVLKVLE.AENKNAFY..EM.....LEEADDFVY..DYDG..EETE..LDYIQKNPEKF
B0UU67_HAES2/219-340             Q.SAKDFTLEQRYLLAINRYFVEVNNGGHHQFFYNSTG..IVWEDALNGLKHFGMNEFAANFQKVIDYCGGTISFDREERCR.MLEILEENE.EE.....F.YKV.....LDEADDFVY..EYEG..EENELI..YIKNHPKKF
C0W1X9_9ACTO/213-335             N.TAQRFTLEQRYLLAMTWYFAEVNNGGHDQFFYNSAGVV..WQDTLNGFKHFGMFDYAGNFQKVIDYCGGA.I.PFDRQER..FDSLEAIR.KE.....N..EETYLALLDEADDFIF..EYDG..ADD..ELHYIQANPEKF
C4G3D4_ABIDE/376-496             K.SAESLTLEQRYLNAVSWYFMEVNNGGHFQFLDNSTG..IVWEDALNGLRLFEMNELADSFQKVIDLFGGK.I.PFDREER..WNAMEELD.EN.....L..EE....LLDEADKLVY..KVYE..YGGEYEIKYIKAHPEKF
C4FQ05_9FIRM/211-330             E.SAKPFTVEQRYLNAISWYFAEVNNGGHHQFFYNSTG..IVWEDALAGLRLFKMDTLADNLQSVIDYFGGS.I.SFDRAER..WTILQDWE.NE.....E..EL.....FDFLDKKDD..VVYE..YDGIYEDTFVHEHPELF
D1YMW7_9FIRM/211-330             E.SSKGFTLEQRYLNAICWYFAEVNNGGHHQFFYNSTG..IVWEDALAGLQRFKMDELANNFQTVLDYFGGT.V.PFDREER..WKLLQQSE.DN.....P..EF.....FEFLDGKDD..VVYE..YDGIFEDAFVHEHPELF
D4DR71_NEIEG/94-215              A.YLQTLSHARRAVYALYILAGEVDNGGFNQYYYNTGAEAA..AYLPEACELVGAPKYADLVRRANACYERE.KLADRQDGS..LEGFCASY.EN.....N..P......LEAYDDEFY..LLENCQPLDGLLVRFIRENPEAF
A5FIX3_FLAJ1/87-202              D.IVMSWNKSKQAVYKVCLFKGEVNNGGYNQFYNNSGVQYY..KDLPDALNLIGAHKFADLTKRANDTFEKE.YERVTKYQ............EK.....FVDDP.....LEEFDDEFF..DLNKTKNLEKLLVDYIRKHKKEL
A1ZW05_9BACT/57-176              K.KLRGFSPGQQALFTLWHLDSEVTSGGFVQFFWNGYAVYV..PVLSNGLNLIEAKAMEQLITEAYEEYQLQ.QSTFTEYAS..LID.SPLY.AE.....L..EK.....LNQMDFEYF..RLHK..KTIDKMEQYIRKYPEEF
D4DQ08_NEIEG/33-156              D.AGEKLTDEQHTLMAYVFLDSQVQEGGFLQLIATGYGDYIFANPLADSLRRWKIKPTPKILDQVKTLYQRY.GAEIEELAG.QGSGLEDIR.RR.....Y..GI.....FEELDGEYY..EASE..SDIQAVAEYIENEWPKF
C6S5G2_NEIML/36-159              E.SLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQH.GETIETLAD.GGADIESLR.KQ.....F..PD.....FEEWDGAYY..EAAE..QDLPLLAEHIQSNWETF
C0ELJ3_NEIFL/38-161              E.DMSGLNDEQHTLTALCYLDSQVQEGGFVQLIASGYGEYIFGNPVADSLRRWRIKPIPKILDKAKALYEKH.GEAIEKMAD.EQRDFDEIR.KA.....F..PD.....FEELDGDYY..DVAD..EDLETAAAYVQANWDKF
D3A070_NEIMU/36-159              E.EMRCLNDEQHTLTAYCYLDSQVQEGGFVQLIAAGYGEYVFHNPVADSLRRWRIKPTPKILDKAKALYERD.GAKIEEMAG.SGASLDAIR.AE.....F..PD.....FEELDGEYY..EIAD..DDMAAAVAYVLANWEKF
C0DXG8_EIKCO/27-150              R.FIERYSGAQRALLAYLSLDLLMEDDGFVLLIADGRGEHALSHETAEYLRQWGVCDTPNIIDRARALYQQH.GAAIQAAAQ.NGSSIEELR.AQ.....F..PQ.....FDELDADYC..LVSE..DDFCTVCPYIRRHPVEF
C4GFB9_9NEIS/27-146              T.TSPRLSGAQNALLAYLRLDKIAEDEGFAMLIALGYGEELLCDQFAEQLATWGVPVLPDIVLQARGLYREL.GAAIGQHGD..AATVREAF.PQ.....F..AV.....VDEW..YFM..ECEE..IFL.KVYNYVRGHFDEF
C2FX52_9SPHI/41-164              NVILNQLCDDQHTLLIYDALYGQVTNGGFLQLIHNGYGPFVFDPVFIEDLERWSLNATAELLKEANVIYLNH.KDYLEEERD..LREFSALC.KH.....F..KE.....FEPFDDLFY..EMME..DEVSRFRKYIEDHIADF
D2F007_9BACE/98-220              G.TMSLLTGEQHSLLAYQIFRDEVMEGGFCQLIQNGYGGYIFDNPFAKVMRLWGVGDLSKLVYAAKKIYDSH.RDDLERERT..DEEFMAMY.EQ.....Y..EA.....FDELEDEFL..EKEE..EYTALVAGYVDEHLELF
C6IR04_9BACE/48-170              D.TMPLLTGEQHSLLAYQIFRDEIMFGGFCQLIQNGYGGYIFDNPFAKVMRLWGAEEFSKLVYKAKKIYDAN.RKDLEKERT..DDEFMAMY.EQ.....Y..EA.....FDDLEEAYL..DMEE..QVTTLVASYVDNHLELF
C6ZAX8_9BACE/43-165              E.TMPLLNGYQHSLLGYHFLREEINEGGFVQLIQNGFGPYIFDNPFAKAMRQFGAKEFAKLIYSAKKIYDEN.RADLEKDRD..DEEFMAMY.EQ.....Y..EA.....FDELEEQFM..DMEE..SVTARIAEYVDNHIEEF
B5CYF6_9BACE/43-165              D.TMPLLNGYQHTLLGYHFFREEVMEGGFVQLIQNGYGPYIFDNPFAKAMRMFGAKEFSKLIYEAKKIYDAH.REDLEKERT..EEEFMAMY.EQ.....Y..EA.....FDDLEEQYM..EEEE..QITAQIATYVDEHLDSF
C9LGK3_9BACT/61-183              E.AFGLLTPDQITLWGYAILREEVMDGGFVQLIHNGYGPFFFHNPFAKALKLWGVDDLARLLRRVDKQYRRH.RNVLTADCT..EAEFMALF.EQ.....Y..PE.....FDDHDDAFI..EGEE..SYTAQIAAYVDEHLDNF
D3IGI0_9BACT/42-164              E.TMSQLNASQITLLAYRILRDEVMDGGFIQLIHNGYGGFIFLNPFAMMVKQWGITELGRLISKAHSNYKKY.HEEIEKDCT..DEEFMSLF.ER.....L..PI.....FDDFDDTFV..EHEE..EWTAAIAQYIDGHIEEF
D3IDY0_9BACT/41-163              T.NMAELNASQITLLAYYVLREEVMDGGFIQLIHNGYGGFIFLNPFSAMMRRWGLGDLCSLINKCHKSYKKH.REVLEAECS..DEEFMALF.EK.....Y..PE.....FDDFDDKFV..EYEE..YWTTKMAEYVDEHIADF
D1W2H6_9BACT/41-163              D.SMQQLNSDQITLLAYHILHQEVMDGGFVQLIHNGYGPFIFRNPFDKALKSWGIQDLSKMIGKCHKLYRKY.AAELEQDCS..DDEFMALF.EK.....Y..PA.....FDDFDDDFV..ENEE..RWTEDVARYVDEHIGQF
D1VZH6_9BACT/41-163              D.TMSQLNADQITLLAYDILHKEVMDGGFIQLIHNGYGAFIFHNPFDKAVRAWGMIDLFRIMKKCHNLYRKY.GAEIERDCS..EDEFMALF.EK.....Y..PE.....FDDYDNTFV..ENEE..RWTSEIANYVDQHIDKF
D1QMD4_9BACT/41-163              D.NMAELNADQITLLAYHYLHEEVMSGGFVQLIHNGYGAFIYKNPTAKAFREWGIHELYGLIRKSHPLYSKY.HEAIERDCT..DDEFMALF.EQ.....F..AE.....FDDFDDAFI..EYEE..MFTSKIAHYIDEHIENF
D1PVD4_9BACT/41-163              E.NMAELNVDQITLLGYVALREEVMNGGFVQLIHNGYGEFIYKNPFHKAVRNWGMQDLYRMINKSRTLYNRY.HEEIEKDCS..QEEFDALY.EK.....Y..AE.....FDDFDDAFV..EGEE..GFTSQVAHYIDEHIENF
D1PGJ9_9BACT/41-163              E.TMAQLNSDQITLLAWDILHEEMMDGGMVQLIHNGYGAFLWKNPTDKAFKNWGLTELAKLIKKSHFLYKTN.HEEIERDLT..DEEFMALY.EK.....F..PE.....FDDFDDEFV..ENEE..EWTSKVAFYIDDHIDNF
D3HVY7_9BACT/41-163              E.NITQLTSDQITLLAWDILHDEVMDGGFVQLIHNGYGAFIYKNPTAKAFREWGLRDLYKLIDKSRRYYNMY.HDEIEQDCT..DEEFMAMF.ER.....F..AK.....FDDFDDDFV..ENEE..EWSNQIAVYVDDHLSDF
C9MQK5_9BACT/41-163              E.TMSQLNADQITLLGWSYLHQEVMEGGYIQLIYNGYGAFIFKNPFAVAMRNWGLRELYTHIKHAKKYYDKY.HEEIEKEVS..DDDFMALY.EQ.....M..PE.....FDEFDDEFI..VNEE..YWCEMIAAYIDDHIDNF
D1XYX1_9BACT/41-163              E.TMAQLTPDQITLLAWDYLHNEVSFGGYVQLIHNGFGAFIFRNPFAVAMRNWGIRDLYTHVKHAKKYYDKY.HEQIEQDMS..DEDFMALF.EQ.....M..PE.....FDDFDDEFV..VNEE..HWTECVAAYIDDHIEDF
Q72QV3_LEPIC/21-142              K.DFLKQSKEQKVFSTIWSLESEVNNGGFTQYFSNGSAETV..HFLIEALKTIGAEKMAQICSDAIKVAFPK.GLPSDPQKI..SNEASEFP.DG.....V.LEN.....LESIDSKFY..EYPD..NLTELLFDFVSKNSKDF
A6EN84_9BACT/44-165              N.NLSTLNTSQQVVLIIENLEREINNGGFNLFYSNSSGNHA..HITVEYLKKIGADKTAELVEKANLEWPNN.NVPKDRTER..QAILKKIE.HK.....A..DQ....VWEDCGQLFY..KYED..DIPYLLMKFVNANRTDF
A4C004_9FLAO/32-152              D.DFRNLNNCEKTFIYLDVLEHNVTNGGFIQFFFNSSGQFA..HEIFHAYMEIKAEKTIEILTEAIHLFPEI.PVPKNLRIR..QEILMEKD.SN.....I..DL.....WDALDTEFY..KCED..DIIKLTLKFVRENLSQF
A3J5H0_9FLAO/32-154              E.DFSSLTDEEKVFVFIDIFEGAMGEGGFEFFFSSESGNFV..EEIITSYQEIKAIKTAELISNAVKIFPKG.Y.DTNLENR..IAAIEKAD.EN.....T.ISG.....WEDLDELFFTNETEE..DVVTLIVNYIKDNENQF
#=GC seq_cons                    -.shppLss-Q+sLlAhphLcpEVpsGGFsQhhtNuhGtalh.pshhcuh+paGhcchscllpcupplYtpp.t.sl-c-pp..tcph.shh.cp.....a..st.....F--hDcpah..-hEE..phsphlspYlcpHh-pF
//