# STOCKHOLM 1.0
#=GF ID   CP_ATPgrasp_2
#=GF AC   PF14403.1
#=GF DE   Circularly permuted ATP-grasp type 2 
#=GF AU   Iyer LM, Abhiman S, Burroughs AM, Aravind L
#=GF SE   Manual
#=GF GA   191.00 191.00;
#=GF TC   195.90 195.60;
#=GF NC   187.90 187.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   20023723
#=GF RT   Amidoligases with ATP-grasp, glutamine synthetase-like and
#=GF RT   acetyltransferase-like domains: synthesis of novel metabolites
#=GF RT   and peptide modifications of proteins.
#=GF RA   Iyer LM, Abhiman S, Maxwell Burroughs A, Aravind L;
#=GF RL   Mol Biosyst. 2009;5:1636-1660.
#=GF DR   INTERPRO; IPR025841;
#=GF CC   Circularly permuted ATP-grasp prototyped by Roseiflexus
#=GF CC   RoseRS_2616  that is associated in gene neighborhoods with a
#=GF CC   GCS2-like COOH-NH2  ligase, alpha/beta hydrolase fold peptidase,
#=GF CC   GAT-II -like	amidohydrolase, and M20 peptidase. Members of this
#=GF CC   family are  predicted to be involved in the biosynthesis of
#=GF CC   small peptides [1].
#=GF SQ   6
#=GS Q02DC9_SOLUE/4-448  AC Q02DC9.1
#=GS A5UWI9_ROSS1/2-461  AC A5UWI9.1
#=GS A9WAS2_CHLAA/3-460  AC A9WAS2.1
#=GS B8GC89_CHLAD/3-460  AC B8GC89.1
#=GS A8M4T7_SALAI/1-452  AC A8M4T7.1
#=GS A8MKZ9_ALKOO/3-442  AC A8MKZ9.1
Q02DC9_SOLUE/4-448             LDDAVAR.YNKLL.ETGPFKDLAWAEALHERMESGKLSAGGRLVCPFL.............RPNFISRRQYESLVKTGESLISAIDRMEQMVLTTP....SLLARLELLPAEKMLASIDPGYQALE.VAARLDSHLVNGH..LHFVQYNADSPTGA.AYADALADLFWDIPPVKEFRKKYTLARLGSRKHLLSALLKSYKQFGGSK.KPNIA.IVEFRPQYSAAQSEYELFRDFFR.......DEGYMVEIVSPEQLEY.RNGVLRK...........GSFEINLVYRRLGVQEFLIRFD...LTHPLVQAYRDRAVCVVNSFRSELAHKKAMFGLLTDESVTSKFPAVERKAIRDHVPWTRLVSAAKTTHNDQTIDLPEFILQNREKLALKPNDDYSDQHTYFGWEMDTAGWERAIKQAMRS.PYVVQERVEPVKSIFP..LMSYGHLEFREMQVDVHPHAYL..GKVQGCSSWLS...MGKTGFSS..AAGIVPTFILDS
A5UWI9_ROSS1/2-461             LETAIAD.YHAAL.QDEAIARATW.EALTVGQRECNLFFGDRPLATVM.............RPRFLTRPQYDLLRRGVGLVVAALQRLGDALLADP....ALRARIALTPQEEALLVRDPGYPYHS.AHSRMDTFLTLDGASLRFVEYNGESPAAI.AYEDVLAELFLSLPAMQQFTRTYAVTPLPARQRLLDTLLDAWAHSGGSG.SPRIA.IVDWSG..LPTHSEFMLFQRYFY.......DHGIEAVICTPDDLAY.RDGRLIATRFQAVEPTAAPAFPIDLVYKRVLTSELLTHYGATALDHPLVRAYADGAICMVNSFRAKLLHKKAIFALLTDESLHDLFTPDERAAIHAHVPWTRLVRPGMTTYQGAAIDLLTFAHAERERLVLKPNDEYGGKGVVIGWETSPDEWARALAEALRT.PSIVQERVTIAYEEYP..AMVDGAVQIGRRLVDSDPFVFG..GEVHGCLCRLS...TVTLLNVTAGGGSTTPVFLVER
A9WAS2_CHLAA/3-460             LAQAIAD.YHALL..EPTLAVESW.QRLTAEMRARRLYFGERPLATVL.............RPRLITASQYELLRRGTQQVAEAARAIVAAALDSSEAGQAVREVLMLTPLEERLIEMHPGYLEPS.AHSRMDTFLTVDGSSLQFVEYNAESPAAI.AYEDLLAQAFLAMPVMQEFAKRYPILPLPARQYLLRTLLDCWRAAGSPGHEPQVA.IVDWHG..VPTATEFEMFRQYFV.......EHGLPAVICAPQDLSF.RDGQLLA......PTPDGGEMPVTIVFKRVLTSEFLTHYGEEALSHPLVQAYAAGACVIVNSFRAKLLHKKSLFALLSDERFHDPLSADQRAAVAAHVPWTRVVRPGTTTYQGEQIDLLSFARANRERLLLKPNDEYGGKGITIGWEVSADEWDAALQAALSS.PFVVQERVTIAYEPYP..ALIDGKVVIGERLVDSDPFLFG..TEVNGCLCRLS...TVTLLNVTAGGGSTVPVFIIDE
B8GC89_CHLAD/3-460             LVQAIAD.YHALL..DPKLAAASW.QCLTEEMRARRLYFGERPLATVL.............RPRLMTMTQYELLRHGTKQVAEAARLIVAAALADDEVGRAVREVLMLTPLEERLIAMHPGYLEPS.AHSRMDTFLTVDGSSLQFVEYNAESPAAI.AYEDLLAQAFLAMPVMQEFIKRYPLLPLPARQYMLRTLLNCWRTAGSPGHEPRVA.IVDWYG..VPTATEFEMFRQYFS.......EHGLPTVICSPHDLVF.RDGQLIA......KTADGGEMPVTIVFKRVLTSEFLSHYGDDALSHPLVQAYAAGACVIVNSFRAKLLHKKSLFALLSDERFHEPLSAEQRSAVAAHVPWTRVVRPGQTTYQGETIDLLAFARANRERLVLKPNDEYGGKGITIGWEVSADAWDAALQAALET.PFVVQERVTIAYEPYP..AFVDGQVVIADRLVDSDPYLFG..TTVHSCLCRLS...TVTLLNVTAGGGSTVPVFVIED
A8M4T7_SALAI/1-452             MTDVDYK.WPSAA........QAW.LDLPADLRADMVSAGVESWREIFDGRASYNQQWRLARPPVMDRTSLRVLNSVCDRLAQLVFEACRRRARTA..G.ELRQLLGMPAGQNRLLDEDEPLTDALLAAFRPDVLLSDGV..PRVVEYNIDSSLGGALDADTTVRRFVEVYRRRGLTDGVRMEPAPSA...VDTRFVAIRSGLNLTAGARVALLIDFEAE.YPGLEDPERFYRKLAPVVDSAAAAGLDLVVAPVAEATQDTEGRLVV...........RGAPVDALFRLFVPNRVSPSP....GVDALEAAVRAGTVPMWVSAAAWLIGNKQVFAWLWADADEL..PAADRDLIHRYVPQTWLFTP..........ELVERAVAEQHDLVVKPSAGSAGVDVLIGRETDAEVWREALGRFAERGGFILQRHVRADNVPVEFVHIETGETVTEEVPYSIAPYLFG..RQPAGACVRIGFPGSAGVLNLA..RGVLISGLLVTD
A8MKZ9_ALKOO/3-442             TTKELYDVYEDIVRKNEGVFLQDH.RAILKKVEESPAKYKGSPVEFLY.............QPMLLSDEDFKRFQDLTDMLLVILNKVIQQYLEEP....TFRSYFGFSPLLEKLILKDPGYKINI.PMGRFDIFYHLDGT.FQFCELNADGSSGM.VEARELQKIIGESFAVTELKKKYSLKDFEVFNSWAEALLANYREFSKTEEKPQIA.IIDWFD..GQPPSEFMEFQKTFE.......AFGCKTIITSPSELTY.RDQKLYH...........GDFRIDCIYRRAVTWEIIEHQD...QVQDFINAYLDGNVCVVGPLRSQVIHNKIVFAILHDEEKTAFLNKEERAFVKKHIPYTREFYA.......ADKELVNFAIENKDTLVLKPMDRYASKGVCIGADFTKEEWAQIIENIAEE.EYILQELCKIPRLPMAMVKENKVDF....IENNYLIGLFMYNEKLQGLYTRTG...TKNIIGSIV.ECYTAPNFVVSE
#=GC seq_cons                  LspAlAD.YculL..s.slthtuW.psLstchRuspLhaGsRPlsslh.............RPpllocsQY-lLp+sscplspAlpclspthLsss....ulRphLtLoPhEE+LlshDPGYhtsp.AtuRhDoFLolDGs.LpFVEYNA-SPuuh.AYtDhLAchFlshPshpEFpK+YsltPLPuRphhLcTLLssaRpuGusstcPplA.IVDWpu..sPstoEFEhFpcaFt.......-aGl.sVIsoPp-Lsa.RDGpLls...........GshPlslVa+RllTsEhLsHas...LsHPLVpAYtsGAlslVNSFRAcLlHKKulFALLoDEphcs.hsA--RuAl+sHVPWTRlVpPu.TTapstsIDLlsFAhANRE+LVLKPND-YuGKGlsIGWEsos-tWcpALppAhco.PalVQERVpIshpPaP..thscGcl.ht-h.VDscPaLFG..scVpGChsRLS...TsslLNlos.uGuTlPsFll--
//