# STOCKHOLM 1.0
#=GF ID   PT-TG
#=GF AC   PF14449.1
#=GF DE   Pre-toxin TG
#=GF AU   Zhang D, Iyer LM, Aravind L, Eberhardt R
#=GF SE   Zhang D, Iyer LM, Aravind L
#=GF GA   23.50 23.50;
#=GF TC   23.50 23.60;
#=GF NC   23.40 23.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21306995
#=GF RT   A novel immunity system for bacterial nucleic acid degrading
#=GF RT   toxins and its recruitment in various eukaryotic and DNA viral
#=GF RT   systems.
#=GF RA   Zhang D, Iyer LM, Aravind L;
#=GF RL   Nucleic Acids Res. 2011;39:4532-4552.
#=GF CC   PT-TG is a conserved region found in many bacterial toxin
#=GF CC   proteins. It could function as a linker that links N-terminal
#=GF CC   secretion-related domain and C-terminal toxin domain. It
#=GF CC   contains a TG motif [1]. 
#=GF SQ   37
#=GS C5D4L3_GEOSW/87-166     AC C5D4L3.1
#=GS YQCG_BACSU/254-329      AC P45942.1
#=GS Q633D6_BACCZ/96-174     AC Q633D6.1
#=GS C3GF60_BACTU/70-148     AC C3GF60.1
#=GS C2YX61_BACCE/122-200    AC C2YX61.1
#=GS C2X396_BACCE/233-311    AC C2X396.1
#=GS A0AFZ4_LISW6/255-330    AC A0AFZ4.1
#=GS D2ENE8_9STRE/80-158     AC D2ENE8.1
#=GS D7UUF6_LISGR/264-335    AC D7UUF6.1
#=GS C8X5D4_DESRD/228-305    AC C8X5D4.1
#=GS C3AW80_BACMY/276-350    AC C3AW80.1
#=GS Q9KAE6_BACHD/24-98      AC Q9KAE6.1
#=GS D3FRB0_BACPE/313-393    AC D3FRB0.1
#=GS D3G073_BACPE/302-372    AC D3G073.1
#=GS F2JRK0_CELLD/1216-1284  AC F2JRK0.1
#=GS C3AFQ9_BACMY/88-168     AC C3AFQ9.1
#=GS C3I390_BACTU/11-91      AC C3I390.1
#=GS A7GMF2_BACCN/102-182    AC A7GMF2.1
#=GS C3AEI4_BACMY/45-125     AC C3AEI4.1
#=GS A1BYS3_BACCE/939-1019   AC A1BYS3.1
#=GS C3GIL3_BACTU/53-134     AC C3GIL3.1
#=GS C3HPW6_BACTU/106-187    AC C3HPW6.1
#=GS Q82CQ1_STRAW/313-385    AC Q82CQ1.1
#=GS B5GTK9_STRCL/294-362    AC B5GTK9.1
#=GS B0LUB6_9ACTO/309-377    AC B0LUB6.1
#=GS D5UI68_CELFN/58-135     AC D5UI68.1
#=GS B7WWR7_COMTE/4319-4403  AC B7WWR7.1
#=GS Q6ML42_BDEBA/272-348    AC Q6ML42.1
#=GS C2TFY3_BACCE/69-146     AC C2TFY3.1
#=GS Q65M71_BACLD/374-449    AC Q65M71.1
#=GS Q65EU5_BACLD/306-381    AC Q65EU5.1
#=GS E5W4J0_9BACI/314-388    AC E5W4J0.1
#=GS YXID_BACSU/327-400      AC P42296.2
#=GS A8FIJ2_BACP2/324-398    AC A8FIJ2.1
#=GS A8FFY0_BACP2/319-393    AC A8FFY0.1
#=GS A5A675_BACLD/36-110     AC A5A675.1
#=GS B4AJF8_BACPU/372-446    AC B4AJF8.1
C5D4L3_GEOSW/87-166                DQTLAENMKEFGL.ELLGWYDLQRLFGEYD.PITGERI.SGWDRLLAGGMLLASF.IPL.IKGIGIAGKVGIKGA....KSARITADVS
YQCG_BACSU/254-329                 YEKSWDAVCNFTG.EVSGYYDYKRAADGVD.PVTGEKL.TAGQRVAAGAMAAAGY.IPI.VGWAGKLAKGG........KAVYSTSKAL
Q633D6_BACCZ/96-174                DRINAKMGMDIVG.ELSGAYDATRAVDGVD.PSTGEKV.GWFDRSVAGVMVVGSM.LQ..VGKLGKIPKVAKAAD....KANEAKKELE
C3GF60_BACTU/70-148                GFDGKKLARDIAG.EVSGEYDVRRAWDGID.PSTGEKL.STWDRIFAGGMAVAGL.TP..VGKIAKVGKGVKMTA....KAAEAANTAK
C2YX61_BACCE/122-200               GESLEKVTRDLVG.ELSGEYDVRRVIEGVD.PDTGEKL.SWWERTGAGVMVFAGL.TP..VGKGIKVVKGAKKVS....NAIDAAATLE
C2X396_BACCE/233-311               TNDLKKAARDLTG.ELSGEYDVRRVMEGVD.PDTGKKL.SWWERTGAGVMVFAGL.TP..VGKGIKLLKGGKKVA....TATKNLLRSD
A0AFZ4_LISW6/255-330               IKSDIKTLLHLGG.EFVLVNDIYRLVNGKD.WLSGEEE....NRAEAAGWLTLSA.LP..VSKLAQIAKELKAGN....RALKGVALSE
D2ENE8_9STRE/80-158                NQENKAKLPTLAA.EFIGWNNGERLVTGKD.PLTGEDANRWAAGAELAVDIASNF.FP..IAKAGKL.RKLEKAL....DAVDAVNDAS
D7UUF6_LISGR/264-335               MEGNTGAIVD....LIDPTQDVLRFFMGRD.PLTDNKL.SKTERGMALL....FL.FP..FAKVGKTFKFAFRGV....EDVERLGKFG
C8X5D4_DESRD/228-305               EQELVARTAELVP.LVGEAMDILAATQGRD..LNGQEL.TTWDRLLRGIMLL....TPEVVGQVGRRYPEALPHL...MKGLQSLAAPE
C3AW80_BACMY/276-350               KRETLALIIDFTP.IIGNIKAGGDVLVGRD.LVRGNKL.TGVDYVLATASIVAGG.EVRAIGKGGVKIK..........NALSEIPTVK
Q9KAE6_BACHD/24-98                 PLQTVSAVLDFLP.FVGNAKAGQEAASGVN.MITEEEL.DEWDRAIAAASVVLGG.....VGKIGGQALKNIL......RGSDDIPDAL
D3FRB0_BACPE/313-393               SREISSAILDFTP.ILGNVKAGYEATHGVD.PITKREL.EDWEQTLMIAAVLGGG.....FVKAGVRGTRGVKSVGFTGKENFNRKEAL
D3G073_BACPE/302-372               SREIGSTVLDFTP.IVGNIKAGVEATRGVD.PITKREL.EDWEKYFAAAGILAGG.....FAKLGSKAV..........KGVKGIDQAN
F2JRK0_CELLD/1216-1284             PGDGLSLVLDLTP.LIGDAKTFIELIEGRD.IITKQEI....NRWLLAGAII....VPRVVSEAIGLFG..........KNADDVAKYI
C3AFQ9_BACMY/88-168                TNELGSMSFDFIP.VIGQIKQGLQLINGKE.YFTDREY.DKNDYVWGTVSTVFGG.APKVIGRVFGKYGELEQKA....KDLGKVSKVT
C3I390_BACTU/11-91                 TTKFMNASLDVWP.IINVPKEIIQLVQGHE.MGEKDKY.KLSDYAIGVASVLTGG.TVKTIGKVVGTVEDIEKKA....KNLERAAKFT
A7GMF2_BACCN/102-182               TNEQISFMLDITP.GVGAIKEGTQMIMGKN.PLTKEQY.GLDDYAWGTLAVVSGG.TSKVVGRVFGKVGDLEKKA....NNLEKAAKNI
C3AEI4_BACMY/45-125                NDGDLSFVLGMTP.IVGTGIEIGQLIKGEN.LVTGQKY.GPEDYEWGTLSVVSGG.TSRVVGKIVGKIGDLEKKG....KAIENATKGT
A1BYS3_BACCE/939-1019              NDGDVSFILGITP.IIGTGKEIGQLIKGED.LVTGQKY.GPDDYAWGTLAVVSGG.TTRVIGKVVGKVGDLEKKG....KALEAAAKNT
C3GIL3_BACTU/53-134                EKSTIKKVWD.GI.VEGTGQAVEDTVEGFKALGKWETWENMGNAALHPIDTLSTM.....YNVLSDSFINDVINGDAESRAKWGSYALT
C3HPW6_BACTU/106-187               QKSDLEKAWD.GL.YDGAGKGVGDAWEGFKALGDGETWSDMWDTVVNYDETLPAM.....WNAFSDSFMNDVWHGDVESGFRWGSYLVT
Q82CQ1_STRAW/313-385               QERRMSMLLNLLP.GIGDGKGVIEAITGTD.LATGEKV.SSTDRVLGSLAVMRWL.......KYGGKLLPEDI......RAARKGDKVP
B5GTK9_STRCL/294-362               QDRRMSLLLGLIP.GIGDGKGVVEAITGKD.LATGEKL.DAYDRATGSLFVLRWI.......KAGGKAL..........KPDDIRKDKS
B0LUB6_9ACTO/309-377               QQRRMGLLLDLLP.GIGDGKGIIEAVTGTD.LATGDEL.TGFDRATGALVVMRWL.......KAGEKAL..........NADDIRNARK
D5UI68_CELFN/58-135                LLAVLSMVLDFVP.GVGTVKGIVEAGTGRD.LLTGQEL.EPWERALGVLPLVGGLAAVAGLSRIGRAGRGA........RMPGEGTRYP
B7WWR7_COMTE/4319-4403             AQELAQLMLELAP.FYGTGESALQLITGKS.SLTGEEA.SRFWAAIGVVPVAGGV.LKKAGEASVSEILKVFKSLHSAEGSINSAVAIE
Q6ML42_BDEBA/272-348               SEVFADLSVGLDP.ITGPLRDVYEAFTGKN.LITGDTL.DSFDRTFAVVGALSFG.....FGSKIGKGLKIFNKI....KNLDFIKAAA
C2TFY3_BACCE/69-146                EKSWWEKGIEGAA.EFIGVNDAIRAVTGKD.PITGKEL.STKERLIAAGWTLLNF.VP..VGKVASLAGKGIKYV.....ASSFGKTIV
Q65M71_BACLD/374-449               PLEPVNDIGDFVAKEIAGGNDAVRVITGRD.PDTGEKV.SNVERAASGT....SL.TP..VGRLLKYGKKGFKLF....KGEEAGKKVA
Q65EU5_BACLD/306-381               EKSDFNKNFDTAM.EFTGVYDAVRAAFGYD.LATGEIVKGNGDRLMAGL....SV.TP..FGKAFKYGKRGFKLF....KGEEAGKKLA
E5W4J0_9BACI/314-388               EVSDLEKYSRIGL.ELLGESDFERAALGYD.PDTYKKL.SLFERFEAAV....NL.TP..PLRIVKWIRKGDKLA....KVSKVDKGAK
YXID_BACSU/327-400                 DENGYVKILETAV.ELTGVYDLFKAATGRD.PVSGEKV.TGKDRVVASI....NS.VP..FAKIAKLEK.LIDIN....KLINNGKKAK
A8FIJ2_BACP2/324-398               TGDQPQNILNTAV.EFTGINDAIRVITGRD.PITGDKV.ANMDRLVSGV....YM.VP..STNIVKVGKYVFKII....KGEKVAKRVE
A8FFY0_BACP2/319-393               DLKQTSNILYTAV.EFTGINDAIRVITGRD.PVTGDKV.ADMDRLVSSL....YM.IP..GAKIAKVGKYVFKIM....KGEKGSKKIV
A5A675_BACLD/36-110                IEKALDWAKDTVG.ELSGGYDGYRAITGVD.PVTGEKL.TVTDRILSGV....SV.IP..ATKVVKVGKYAFKAT....KGAKTAKRVS
B4AJF8_BACPU/372-446               DGEVVSTAENIIL.EYSGIYDGYRAVTGKD.PETSQNI.SRTDQVLSVA....SI.IP..IAKIVKVGKYVFKMD....QGKNAVKRVT
#=GC seq_cons                      pppthshhh-hss..lushp-shcshpGpD..hTG-cl.shh-Rshuul.hh.uh.hs..huKlsphstth.thh....+uhcsstcsp
//