# STOCKHOLM 1.0
#=GF ID   Endonuc_BglI
#=GF AC   PF14562.1
#=GF DE   Restriction endonuclease BglI
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:O68557
#=GF GA   25.00 25.00;
#=GF TC   25.10 25.30;
#=GF NC   24.80 20.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9736624
#=GF RT   Crystal structure of restriction endonuclease BglI bound to its
#=GF RT   interrupted DNA recognition sequence.
#=GF RA   Newman M, Lunnen K, Wilson G, Greci J, Schildkraut I, Phillips
#=GF RA   SE;
#=GF RL   EMBO J. 1998;17:5466-5476.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF CC   This restriction endonuclease binds DNA as a dimer. BglI
#=GF CC   recognises and cleaves the interrupted DNA sequence GCCNNNNNGGC
#=GF CC   and cleaves between the fourth and fifth unspecified base pair
#=GF CC   to produce 3' overhanging ends [1].
#=GF SQ   3
#=GS T2B1_BACIU/6-297    AC O68557.1
#=GS T2B1_BACIU/6-297    DR PDB; 1DMU A; 6-297;
#=GS C1CZ61_DEIDV/1-276  AC C1CZ61.2
#=GS B4VYL0_9CYAN/6-295  AC B4VYL0.1
T2B1_BACIU/6-297               REKIFMSYNQNKQYLEDNPEIQEKIELYGLNLLNEVISDNEEEIRADYNE.ANFLHPFWMNYPPLDRGKMPKGDQIPWIEVGEKAVGSKLTRLVSQREDITVREIGLPTGPDERYLLTSPTIYSLTNGFTDSIMMFVDIKSVGPRDSDYDLVLSPNQVSGNGD.WAQLEGGIQNNQQTI..QGPRS.SQIFLPTIPPLYILSDGTIAPVVHLFIKPIYAMRSLT.KGDTGQSLYKIKLASVPNGLGLFCNPGYAFDSAYKFLFRPGKDDRTKSLLQKRVRVDLRVLDKIGP.RVMTIDM
#=GR T2B1_BACIU/6-297    SS    HHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHH.HHHTHHHHTTS-----SSS--SS----HHHHHHHTHHHHHHHHHTSTT-EEE----SS--SEEEEEE-HHHHHHTTTS-SEEEEEEEE--B-TTS-TTEEEE-GGG-B---B.--STTS--B---EEE..E-SS-.EEEE---B-SEEE-TT--EEEEEEEEEEEEEEEGGGS.TT---EEEEEEEEEEE--HHHHHTSS-GGG-GGGTTSEEE-S--TTS-TTS--EEEEHHHHTTSSS.-EEEEE-
C1CZ61_DEIDV/1-276             MNDLHQKYMKERASLLSNLDELIEMEQKYMSVMVNIIKEAAEDMHQDFHEFGPELLPFWRNYPPEQRGRAFRNEAIPMLELGEKLVGSHIIKAVCHKLE.NVRFPGLPTGGDIRFM.............TDDAFIHCDIKITGPNEVDNEVVVPPNQVSGDGEHWDAF..GLRNNHWPIHYRGSRGLNFNFQPKLPPLYLAGDKRRV.CLTFYIKAVYSTVEY.....GVHPIRHFEVVCVPNGLLMFSNGVHSYAKA.DGLITSGKDEVTKDSSTRRIRVKLNPLARIANWRAVKMER
B4VYL0_9CYAN/6-295             RQFQYNSYRTARNYFIQNYNQLINLEKYVLEEVFNSVHQNLAEIIANYNE.ASYLYPFWQNYPPEERGRQPIGDQYPWLEVAEHTIGDKLPRLLECNFE..ISDVGLPTGSDLRLVISNYRISQITNDVTNSCWLFLEIKSVGPRDDQDHAVMSHNQISGSGR.WEVFSDGISNDIITA..TGKRA.NHPFYCSLPPIYILSDGLIVPVVIIIVKPVYRMLSLEGNDDGGQPLSRISFASVPNGLLLHEQPHYLMN..FPDLFFPGKDEMKKDPRKRRCRVSFEILSRIDSWRFREIDC
#=GC SS_cons                   HHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHH.HHHTHHHHTTS-----SSS--SS----HHHHHHHTHHHHHHHHHTSTT-EEE----SS--SEEEEEE-HHHHHHTTTS-SEEEEEEEE--B-TTS-TTEEEE-GGG-B---B.--STTS--B---EEE..E-SS-.EEEE---B-SEEE-TT--EEEEEEEEEEEEEEEGGGS.TT---EEEEEEEEEEE--HHHHHTSS-GGG-GGGTTSEEE-S--TTS-TTS--EEEEHHHHTTSSS.-EEEEE-
#=GC seq_cons                  RpclapSYppsRsYLlsNh-pLIclEpYsLsllsNlI+-NtEEI+ADYNE.AsaLaPFWpNYPPE-RGRtP+GDQIPWLEVGEKsVGSKLsRLVsp+hE.sVR-lGLPTGuDlRallos.pI.plTNshTDSsalFlDIKSVGPRDsDs-lVlSPNQVSGsG-.W-sFpsGIpNNphTI..pGsRu.NasFhPoLPPLYILSDGpIVPVVplaIKPVYuMlSLp.psDGGQPLp+IclASVPNGLLLFsNPsYuaspAacsLFpPGKDEhTKDsppRRlRVcLclLuRIusWRshcIDp
//