Summary: rRNA processing/ribosome biogenesis
rRNA processing/ribosome biogenesis Provide feedback
Rix1 is a nucleoplasmic particle involved in rRNA processing/ribosome assembly [1,2]. It associates with two other proteins, Ipi1 and Ipi3, to form the RIX1 complex that allows Rea1 - the AAA ATPase - to associate with the 60S ribosomal subunit. More than 170 assembly factors are involved in the construction and maturation of yeast ribosomes, and after these factors have completed their function they need to be released from the pre-ribosomes. Rea1 induces the release of the assembly protein complex in a mechanical fashion . This family is usually associated with NUC202, PF08166.
Nissan TA, Bassler J, Petfalski E, Tollervey D, Hurt E;, EMBO J. 2002;21:5539-5547.: 60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm. PUBMED:12374754 EPMC:12374754
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This tab holds annotation information from the InterPro database.
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Curation and family details
|Seed source:||Staub E|
|Author:||Staub E, Bateman A, Mistry J|
|Number in seed:||37|
|Number in full:||221|
|Average length of the domain:||166.40 aa|
|Average identity of full alignment:||23 %|
|Average coverage of the sequence by the domain:||20.46 %|
|HMM build commands:||
build method: hmmbuild --amino -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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