Summary: Relaxase/Mobilisation nuclease domain
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Relaxase/Mobilisation nuclease domain Provide feedback
Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalysing .
Meyer R; , J Bacteriol 2000;182:4875-4881.: Identification of the mob genes of plasmid pSC101 and characterization of a hybrid pSC101-R1162 system for conjugal mobilization. PUBMED:10940031 EPMC:10940031
Bravo-Angel AM, Gloeckler V, Hohn B, Tinland B; , J Bacteriol 1999;181:5758-5765.: Bacterial conjugation protein MobA mediates integration of complex DNA structures into plant cells. PUBMED:10482518 EPMC:10482518
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR005094Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalysing trans-esterification [PUBMED:9350859].
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Curation and family details
|Seed source:||Pfam-B_4002 (release 6.6)|
|Author:||Finn RD, Mifsud W, Bateman A|
|Number in seed:||17|
|Number in full:||2990|
|Average length of the domain:||226.00 aa|
|Average identity of full alignment:||16 %|
|Average coverage of the sequence by the domain:||49.85 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||9|
|Download:||download the raw HMM for this family|
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